一种吸收比率 / 荧光淬灭双模式一氧化氮荧光探针及其制备方法和应用
By developing a dual-mode nitric oxide fluorescent probe with absorption ratio and fluorescence quenching, the problems of complex sample pretreatment, poor anti-interference ability and low spatiotemporal resolution in NO detection in existing technologies have been solved, and high-sensitivity self-calibrated quantitative detection in complex environments has been achieved.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- ZHENGZHOU NORMAL UNIV
- Filing Date
- 2026-06-03
- Publication Date
- 2026-07-17
AI Technical Summary
Existing NO detection methods suffer from problems such as complex sample pretreatment, poor anti-interference ability, and low spatiotemporal resolution in real-world environments or biological samples. Traditional single-mode fluorescent probes are difficult to achieve accurate quantification in complex systems.
A dual-mode nitric oxide fluorescent probe based on absorption ratio and fluorescence quenching was developed. By utilizing the ratio of the two absorption peaks in the UV-Vis absorption spectrum and the fluorescence quenching characteristics in the fluorescence emission spectrum, self-calibrated quantitative detection can be achieved.
It achieves highly sensitive and interference-resistant quantitative detection of NO in complex environmental matrices, suitable for rapid on-site screening and precise laboratory quantification, and reduces preparation costs.
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Figure CN122404356A_ABST
Abstract
Citation Information
Patent Citations
Nitric oxide fluorescent probe as well as preparation method and use method thereof
CN119874566A