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Sheep lamb increasing essence

A technology of goat and androstenedione, which is applied in the fields of peptide/protein components, diseases, antibody medical components, etc., can solve the problems of high price of human serum albumin, high production cost, and economical uneconomical, etc., and achieve shortening of genetic breeding process, increase the lambing rate, and the effect of simple and easy operation

Inactive Publication Date: 2006-05-31
王利智
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

Its disadvantage is that human serum albumin and DEAE dextran are expensive, the production cost is high, and it is not economically cost-effective and does not suit the national conditions.

Method used

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Experimental program
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Embodiment Construction

[0021] A kind of goat lambsin, the chemical structure of its compound is androstenedione-17-carboxymethyloxime-bovine serum albumin. Use mineral oil to emulsify the adjuvant and antigen to form a two-phase emulsion of oil-in-water-in-water. The adjuvant ingredients are No. 25 white oil, Span 85 (sorbitan trioleate), and Tween 80 (polyethylene sorbitan monooleate).

[0022] Firstly, after freeze-drying the synthesized androstenedione-17-carboxymethyloxime-bovine serum albumin, the antigen aqueous solution is prepared according to production requirements; and then an emulsifier (adjuvant) is used. The emulsifier is to mix No. 25 white oil, Span 85 and Tween 80 in a ratio of 1:0.1:0.25, mix and stir in the colloid mill, and then slowly add the prepared antigen aqueous solution to the colloid mill. 1 part of emulsifier, 2 parts of antigen solution. The speed of the colloid mill is 5000 rpm.

[0023] The test method for the success or failure of emulsification:

[0024] ① Injec...

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Abstract

The invention discloses a hormone immune preparation for promoting fecundity of sheep and goats synthesized by using androstenedione-17-carboxymethyloxime-bovine serum albumin, which has a specific effect on promoting the production of twin lambs in sheep and goats. The preparation has no toxic and side effects, low cost, high ovulation rate, remarkable double lambing rate, etc., and is comparable to similar foreign products. Its application and popularization will definitely have a great impetus to the implementation of animal husbandry structure adjustment and the development of my country's breeding industry.

Description

technical field [0001] The invention relates to the reproduction of female animals, which is a preparation for promoting the fecundity of ewes by immunizing with steroid hormones. Background technique [0002] The Australian Commonwealth Science and Industry Organization (CSIRO) developed and produced a twin seedling called "Fecundin" in the early 1980s (1982-1983) (see reference 1, In Gordon, 1983, Control and manipulation of reprkduction in sheep .In: Controlled Breeding in FarmAnimals.pergamon press.Oxford.2, Linday, D.R.at al.1980 influence of behavior onreproduction.In:9th International congress on Animal Reproduction and ArtificialInsemination.1:83-92.3, Van Benlun, 1987, abroad Introduction of New Veterinary Drugs (5), Foreign Animal Husbandry Science and Technology 4: 58). Its chemical composition is androstenedione-7α-carboxyethyl sulfide-human serum albumin, and the adjuvant is 5% diethylaminoethyl-dextran saline solution. According to literature ① In Gordon, 198...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/38A61K39/39A61K9/107A61P15/08
Inventor 王利智张银定王益慧
Owner 王利智