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Actacid composition

A composition and antacid technology, applied in the direction of drug combination, digestive system, electrical components, etc., can solve the problems of increasing the dosage, not being very satisfied, and reducing compliance

Inactive Publication Date: 2006-04-19
KOWA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in order to achieve sufficient acid control effect, the dosage must be increased
As a result, problems such as reduced compliance and restrictions on other drug ingredients, such formulations are not very satisfactory

Method used

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  • Actacid composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Take 33 mg of magnesium hydroxide (magnesium hydroxide: manufactured by Tomita Pharmaceutical Co., Ltd.), 300 mg of sodium bicarbonate (sodium bicarbonate: manufactured by Asahi Glass), and 400 mg of precipitated calcium carbonate (precipitated calcium carbonate: manufactured by Bihoku Fen Chemical Industry Co., Ltd.), and mix them uniformly in a mortar. An antacid composition is obtained.

Embodiment 2

[0037]Take 33 mg of magnesium hydroxide, 200 mg of sodium bicarbonate and 500 mg of precipitated calcium carbonate, and mix them uniformly with a mortar to obtain an antacid composition.

Embodiment 3

[0039] Take 67 mg of magnesium hydroxide, 300 mg of sodium bicarbonate and 500 mg of precipitated calcium carbonate, and mix them uniformly with a mortar to obtain an antacid composition.

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PUM

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Abstract

An actacid composition containing no aluminum, which comprises magnesium hydroxide, sodium hydrogencarbonate and calcium carbonate and exhibits a maximum reaching pH in the modified Fuchs method of 5 to 7. The actacid composition combines the fast-acting property and the persistence with respect to its deacidification action and does not cause the rebounding secretion of an acid and further does not contain aluminum.

Description

technical field [0001] The present invention relates to an antacid composition which has quick-acting and sustained acid neutralizing effect, does not cause rebound acid secretion, and does not contain aluminum. Background technique [0002] Gastrointestinal drugs are generally used to relieve hyperacidity, heartburn, stomach discomfort, bloating, indigestion, gastric heavyness, chest tightness, belching, nausea, vomiting, excessive drinking, stomach pain and other symptoms. Most gastrointestinal medicines in the world contain antacids that neutralize the gastric acid secreted into the stomach and inhibit the activation of pepsin. [0003] Gastrointestinal drugs containing antacids are not only expected to neutralize gastric acid immediately after administration and relieve symptoms quickly, but are also expected to have the effect of continuously neutralizing gastric acid secreted immediately after. In addition, it is also an important element not to cause rebound acid sec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/10A61K33/00A61K33/08A61P1/04H04R1/02A61K45/06H03G5/00H03G5/02H03G5/22H04R3/00H04R3/04H04R29/00
CPCA61K33/00A61K45/06H03G5/025A61K33/08H03G5/005A61K33/10H03G5/22A61P1/04A61P1/08A61K2300/00
Inventor 久我宏彰狩野祐一郎玉田亮宏川島弘行
Owner KOWA CO LTD
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