Methods for treating skin conditions
一种视黄醇、组合物的技术，应用在治疗和改善皮肤症状领域，能够解决致畸等问题
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Embodiment 1
[0045] Example 1 Preparation of Naturally Derived Products Containing STI
[0046] According to analytical tests, soy milk and soy milk are rich in soybean trypsin inhibitors.
[0047]To prepare soymilk, soybeans are first soaked in deionized or purified water for several hours, and after they are fully hydrated, they are milled and a small amount of water is added. Smooth the soy milk if desired. To prepare soy milk, add more water and do the same steps (milling process allows soy milk to drain). After collection, the soy milk is filtered to remove the residue of the bean skin.
[0048] Soymilk, soymilk and soy paste (miso) were prepared as containing natural derivatives of STIs that lighten the skin.
Embodiment 2
[0049] Example 2 Nursing preparations containing soy milk
[0050] In preparing soy milk, applicants have found that soy milk, which has a very good emollient effect, is suitable for skin care agents. Because water is the main ingredient in any oil-in-water emulsion, and in many other skin care formulations, we hypothesized that soy milk could serve as a substitute for deionized water in these formulations. However, we foresee that this type of dosage form will be physically unstable due to the immiscibility of oil and water in soy milk. Applicants were surprised to find that this soy milk was physically stable in place of water. Formulations using soy milk should contain from about 1% to 99% soy milk, more preferably from about 80% to 95% soy milk. Such and similar formulations preferably contain from about 0% to 5% (more preferably, from about 0.1% to 2%) of a viscosity aid, about 20% of one or more lubricants and / or from about 0.1% to 10% (more preferably about 3% to 5%)...
Embodiment 3
[0054] Example 3 Oil-in-water skin care preparation
[0055] In Table B are two specific examples of oil-in-water skin care formulations. Column 3 of Table B describes a formulation comprising an STI, wherein the STI may be replaced by any naturally derived serine protease inhibitor, or any natural derivative or ingredient containing a serine protease inhibitor. The therapeutic component of the composition may be replaced by a serine protease inhibitor or a PAR-2 inhibitor having a high therapeutic index, whether the active ingredient is obtained synthetically or naturally. In these formulations, the recommended content ranges of the ingredients are listed in Table B. The deionized water in the preparation can be replaced by soybean milk.
[0056] Mutually
[0057] To prepare this formulation, the lipid phase components were combined and mixed at 85°C, then cooled to 60°C. In a separate container, slowly add Carbomer to the water or soy milk. After mixing for ...
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