Compound lentinan preparation and its preparing method
The technology of lentinan and compound recipe is applied in the field of compound lentinan preparation and its preparation, which can solve the problems of high import price and the like, and achieve the effects of synergistic treatment, enhancing immunity and inhibiting the growth of tumor cells.
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Embodiment 1
[0023] Take 2 grams of lentinan for injection, put it into a container and dissolve it with 700 ml of 0.6 mol / L sodium hydroxide aqueous solution at room temperature. After dissolving, add 400ml of common 20% mannitol injection, stir evenly, add 0.05 grams of sodium cantharidate, adjust the pH of the solution to 9 with 1mol / L citric acid solution after dissolving, filter, concentrate under reduced pressure to 1000ml, sterile filter, Sterilize, measure the content, subpackage, 1ml / bottle, cool and dry, and seal to obtain compound lentinan freeze-dried powder injection.
Embodiment 2
[0025] Take 2 grams of lentinan for injection, put it into a container and dissolve it at room temperature with 600 ml of 0.8mol / L sodium hydroxide aqueous solution, add 400 ml of ordinary 20% mannitol injection and 1.6 grams of dextran after dissolving, stir well, add sodium cantharidate 0.05 gram, after dissolving, use 1mol / L citric acid solution to adjust the pH of the solution to 9, filter, concentrate under reduced pressure to 1000ml, sterile filter, sterilize, measure the content, subpackage, 1ml / bottle, cool and dry, seal to obtain compound shiitake mushrooms Polysaccharide freeze-dried powder injection.
Embodiment 3
[0027] Take 2 grams of lentinan for injection, put it into a container and dissolve it with 500 ml of 0.8 mol / L sodium hydroxide aqueous solution at room temperature. After dissolving, add 100ml of 10% hydroxypropyl-β-cyclodextrin aqueous solution, stir well, add 0.05 g of sodium cantharidinate, adjust the pH of the solution to 9 with 1mol / L citric acid solution after dissolving, filter, add water for injection to 1000ml , aseptically filtered, sterilized, measured, subpackaged, 1ml / bottle, cooled and dried, and sealed to obtain compound lentinan freeze-dried powder for injection.
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