Extractive of traditional Chinese medicine, its prepns., preparing method and application thereof

A technology of traditional Chinese medicine preparations and extraction methods, applied in the directions of drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve the problems of poor dosage forms, biased in promoting blood circulation, loss of active ingredients, etc., and achieve significant curative effects, improve blood circulation, and improve blood supply.

Inactive Publication Date: 2007-01-31
祝国光
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the above clinical prescriptions and Chinese patent medicines all have certain deficiencies, such as invigorating qi, invigorating yang, invigorating blood, or poor dosage forms, and have not been fully promoted clinically.
[0004] And in the prior art, angelica, chuanxiong and safflower mostly extract their active ingre

Method used

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  • Extractive of traditional Chinese medicine, its prepns., preparing method and application thereof
  • Extractive of traditional Chinese medicine, its prepns., preparing method and application thereof
  • Extractive of traditional Chinese medicine, its prepns., preparing method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0139] Example 1 Active ingredient preparation example

[0140] Weigh 600g of Angelica sinensis and 400g of Ligusticum chuanxiong in the extraction kettle, adjust the extraction temperature to 35℃, pressure to 30Mpa, CO 2 The flow rate is 30kg / h, the entrainer is 3% acetone, the separation tank 1: the temperature is 45°, the pressure is 10Mpa, the separation tank 2: the temperature is 40℃, the pressure is 5Mpa, after 3 hours of extraction, a total of 56g of extracts are collected from the separation tanks 1 and 2 .

Example Embodiment

[0141] Example 2 Active ingredient preparation example

[0142] Weigh 460g of Angelica sinensis and 540g of Ligusticum chuanxiong in the extraction kettle, adjust the extraction temperature to 30℃, pressure to 40Mpa, CO 2 The flow rate is 20kg / h, the entrainer is 4% acetone, the separation vessel 1: the temperature is 45°, the pressure is 10Mpa, the separation vessel 2: the temperature is 40°C, the pressure is 5Mpa, and the total extract is collected from the separation vessel 1 and 2 after extraction for 1.5 hours. 52g.

Example Embodiment

[0143] Example 3 Active ingredient preparation example

[0144] Weigh 480g of Angelica sinensis and 520g of Ligusticum chuanxiong in the extraction kettle, adjust the extraction temperature to 40℃, pressure to 35Mpa, CO 2 The flow rate is 25kg / h, the entrainer is 2% acetone, the separation tank 1: the temperature is 45°, the pressure is 10Mpa, the separation tank 2: the temperature is 40℃, the pressure is 5Mpa, and the total extracts are collected from the separation tanks 1 and 2 after extraction for 2.5 hours. 52g.

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Abstract

A Chinese-medicinal extract is prepared from Chinese angelica root, Chuan-xiong rhizome and optional safflower through extracting by supercritical CO2 fluid. A Chinese medicine in the form of capsule, tablet, dripping pill, or particle for treating cardiovascular and cerebrovascular diseases contains said extract and optional borneol.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular, it is an extract extracted from angelica, chuanxiong or angelica, chuanxiong and safflower in proportion, a preparation containing the extract and a preparation method thereof. Background technique [0002] According to my country's epidemiological survey, the incidence and mortality of cardiovascular and cerebrovascular diseases have been on the rise in the past 50 years, whether in rural areas or cities. In the 1950s and 1960s, cardiovascular disease and cerebrovascular disease ranked fifth and sixth respectively among the causes of death in my country, and rose to second and third respectively after 1970. Cardiovascular and cerebrovascular diseases accounted for the first of all causes of death. The percentage of people who died of cardiovascular and cerebrovascular diseases in the total death population in my country has risen from 1...

Claims

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Application Information

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IPC IPC(8): A61K36/232A61K36/286A61K9/48A61K47/44A61P9/10
Inventor 祝国光
Owner 祝国光
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