Unlock instant, AI-driven research and patent intelligence for your innovation.

Medicine composition for treating myasthenia gravis and prepn. method therefor

A technology of composition and medicine, which is applied in the field of pharmaceutical composition and its preparation, Chinese patent medicine for treating myasthenia gravis and its preparation, which can solve problems such as cumbersomeness, influence on the development of finished medicine and improvement of dosage forms, and influence on curative effect, etc.

Active Publication Date: 2007-01-31
合肥铨键中医药研究合伙企业(有限合伙)
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the recurrent attacks of MG and the persistent non-healing, long-term medication is required, and the traditional Chinese medicine decoction is cumbersome and inconvenient, making it difficult to take the medicine quickly and in a timely manner, which affects the effectiveness of the curative effect; in addition, the specific classification of MG has not been standardized and standardized. The clinical observation of prescriptions often lacks comparability and repeatability, and the addition and subtraction of prescriptions according to the syndrome has seriously affected the development of patented medicines and the improvement of dosage forms.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicine composition for treating myasthenia gravis and prepn. method therefor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] [Example 1] Preparation of granules

[0064] Weigh each raw material (unit: g) according to the following weight:

[0065] Polygonum multiflorum 400, Tortoise shell 400, Ginseng 300, Rhodiola rosea 400, Curcuma 300, Atractylodes macrocephala 300, Polygala 100;

[0066] Pre-treatment of raw materials: processing Polygonum multiflorum into Radix Polygoni Multiflori; processing ginseng into raw sun-dried ginseng; The processing method of above-mentioned raw material is with reference to the method recorded in " Dictionary of Chinese Medicine " (Shanghai Science and Technology Press);

[0067] Sun-dried ginseng, Shouwu and Rhodiola were extracted three times under reflux with 60% ethanol, adding 6 times the weight of ethanol each time, and extracted for 1.5 hours; 50°C~60°C), extract 1 for later use; Atractylodes Rhizoma Atractylodes Rhizome and Curcuma officinalis add water 5 times, steam distillation method extracts volatile oil for 6 hours, collects volatile oil, and i...

Embodiment 2

[0069] [Example 2] Preparation of granules

[0070] Weigh each raw material (unit: g) according to the following weight:

[0071] Polygonum multiflorum 200, Tortoise shell 200, Ginseng 150, Rhodiola rosea 200, Curcuma 200, Atractylodes macrocephala 200, Polygala 100;

[0072] Pre-treatment of raw materials: processing Polygonum multiflorum into Radix Polygoni Multiflori; processing ginseng into raw sun-dried ginseng; The processing method of above-mentioned raw material is with reference to the method recorded in " Dictionary of Chinese Medicine " (Shanghai Science and Technology Press);

[0073] Sun-dried ginseng, Shouwu and Rhodiola were extracted three times under reflux with 60% ethanol, adding 6 times the weight of ethanol each time, and extracted for 1.5 hours; 50°C~60°C), extract 1 for later use; Atractylodes Rhizoma Atractylodes Rhizome and Curcuma officinalis add water 5 times, steam distillation method extracts volatile oil for 6 hours, collects volatile oil, and i...

Embodiment 3

[0075] [Example 3] Preparation of granules

[0076] Weigh each raw material (unit: g) according to the following weight:

[0077] Polygonum multiflorum 600, Tortoise shell 600, Ginseng 600, Rhodiola rosea 800, Curcuma 600, Atractylodes macrocephala 500, Polygala 300;

[0078] Pre-treatment of raw materials: processing Polygonum multiflorum into Radix Polygoni Multiflori; processing ginseng into raw sun-dried ginseng; The processing method of above-mentioned raw material is with reference to the method recorded in " Dictionary of Chinese Medicine " (Shanghai Science and Technology Press);

[0079] Sun-dried ginseng, Shouwu and Rhodiola were extracted three times under reflux with 60% ethanol, adding 6 times the weight of ethanol each time, and extracted for 1.5 hours; 50°C~60°C), extract 1 for later use; Atractylodes Rhizoma Atractylodes Rhizome and Curcuma officinalis add water 5 times, steam distillation method extracts volatile oil for 6 hours, collects volatile oil, and i...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A Chinese medicine in the form of pill, capsule, tablet, powder, particle, or oral liquid for treating myasthenia gravis is prepared from 7 Chinese-medicinal materials including fleece flower root, tortoise plastron, ginseng, rhodiola root, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a Chinese patent medicine for treating myasthenia gravis mainly prepared from Chinese herbal medicines as raw materials and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Myasthenia Gravis (MG) is an autoimmune disease that affects the acetylcholine receptors at the neuromuscular junction, and can affect multiple muscle groups throughout the body. Its main features are progressive muscle contraction weakness and fatigue, which can be recovered after rest. Most patients show ptosis and diplopia in the early stage. The clinical incidence rate of myasthenia gravis is 80-200 cases per one million people, and the incidence rate is related to gender and age. Myasthenia in 15% of patients only involves extraocular or eyelid muscles, and about 85% of patients develop generalized myasthen...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P21/04A61K35/56A61K35/586
Inventor 卜绿萍兰金初
Owner 合肥铨键中医药研究合伙企业(有限合伙)