Compositions and methods for the inhibition of ras
CO20260008639A2Pending Publication Date: 2026-08-31LEIDOS BIOMEDICAL RESEARCH INC +2
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Patent Information
- Application Number
- CO20260008639
- Authority / Receiving Office
- CO · CO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-11-27
- Filing Date
- 2026-06-11
- Publication Date
- 2026-08-31
Abstract
This document provides compounds, or salts, esters, tautomers, prodrugs, zwitterionic forms or stereoisomers thereof, as well as pharmaceutical compositions comprising them. It also provides methods of using these for the modulation (e.g., inhibition) of KRAS (e.g., KRAS having a Q61H, G12D, G12V, G12C, G12S, G12A, G12R or G13D mutation or wild-type KRAS, including amplified wild-type KRAS) and for the treatment of diseases or disorders, such as cancers, in subjects requiring them.
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