Fusion proteins comprising acid alpha-glucosidase enzymes and methods thereof

CO20260010351A2Pending Publication Date: 2026-10-08DENALI THERAPEUTICS INC
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Patent Information

Application Number
CO20260010351
Authority / Receiving Office
CO · CO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-12-19
Filing Date
2026-07-17
Publication Date
2026-10-08
Patent Text Reader

Abstract

Proteins that can be transported across the blood-brain barrier (BBB) ​​and comprise an acid alpha-glucosidase (GAA)-Fc enzyme fusion polypeptide are provided. Certain modalities also provide methods for using such proteins to treat Pompe disease.
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