Methods for characterizing and purifying the vegf receptor fusion protein

CO20260010393A2Pending Publication Date: 2026-07-31REGENERON PHARMACEUTICALS INC
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Patent Information

Application Number
CO20260010393
Authority / Receiving Office
CO · CO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-12-19
Filing Date
2026-07-17
Publication Date
2026-07-31
Patent Text Reader

Abstract

Anti-VEGF proteins, including the VEGF receptor fusion protein aflibercept, can be produced to have a low level of an aspartic protease (e.g., a low level of cathepsin D), such as less than 1 ppm of aspartic protease.
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