CO-CULTURES OF IMMUNE CELL ORGANOIDS
DK3729084T3Active Publication Date: 2026-07-06KONINK NEDERLANDSE AKADE VAN WETENSCHAPPEN +1
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Patent Information
- Application Number
- DK2018830837T
- Authority / Receiving Office
- DK · DK
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2018-12-21
- Filing Date
- 2018-12-21
- Publication Date
- 2026-07-06
- Estimated Expiration
- 2038-12-21
AI Technical Summary
Technical Problem
Current in vitro models for investigating and treating cancer and immune diseases lack the representation of multiple cell types, particularly the interaction between cancer organoids and immune cells, limiting their accuracy and effectiveness in replicating patient physiology.
Method used
Development of tumouroid co-cultures comprising immune cells and tumour epithelial cells, prepared using specific culture media with IL-2, to replicate patient-specific interactions and test candidate agents or therapies for efficacy and safety.
Benefits of technology
The method enables high-throughput screening of candidate agents for treating cancer and immune diseases by accurately mimicking patient-specific immune responses, enhancing the accuracy and efficiency of treatment regimens.
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