Anti-csp antibody variants

Anti-cyclosporine antibodies are developed to address the lack of effective CSP-targeting antibodies in malaria treatments, providing therapeutic options for malaria prevention and treatment.

HK40134683APending Publication Date: 2026-07-10ATRECA INC

Patent Information

Authority / Receiving Office
HK · HK
Patent Type
Applications
Current Assignee / Owner
ATRECA INC
Filing Date
2026-04-16
Publication Date
2026-07-10

AI Technical Summary

Technical Problem

Current treatments for malaria lack effective antibodies targeting cyclosporine (CSP), which are essential for treating or preventing the disease.

Method used

Development of anti-cyclosporine (CSP) antibodies and compositions comprising these antibodies for therapeutic use against malaria, along with methods for selecting and producing such antibodies.

Benefits of technology

Provides antibodies that effectively target CSP, offering potential treatments and prevention strategies for malaria.

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Abstract

The present disclosure provides anti-circumsporozoite (CSP) antibodies, compositions comprising such antibodies. Also disclosed are methods of producing the disclosed antibodies and methods of treating or preventing malaria using the same. Also disclosed are methods of selecting an antibody as an anti-malaria therapeutic antibody.
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