Menin-mll interaction inhibitor and preparation method therefor, and application

A Menin-MLL interaction inhibitor addresses the lack of effective treatments for diseases mediated by this interaction by offering a targeted therapeutic solution for tumors and diabetes.

HK40135697APending Publication Date: 2026-07-31BEYOND THERAPEUTICS CO LTD
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Patent Information

Application Number
HK62026123598
Authority / Receiving Office
HK · HK
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-09-27
Filing Date
2026-05-19
Publication Date
2026-07-31

AI Technical Summary

Technical Problem

Current treatments for diseases mediated by Menin-MLL interaction, such as tumors and diabetes, lack effective inhibitors targeting this interaction.

Method used

Development of a Menin-MLL interaction inhibitor compound.

Benefits of technology

The compound effectively targets and inhibits the Menin-MLL interaction, providing a potential therapeutic approach for diseases like tumors and diabetes.

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Abstract

The invention discloses a Menin-MLL interaction inhibitor as well as a preparation method and application of the Menin-MLL interaction inhibitor. The compound is expected to be used for treating Menin-MLL interaction mediated diseases such as tumors and diabetes mellitus.
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Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202480060440.8 (22) Application Date 2024.09.23 (66) Domestic Priority Data 202311262366.1 2023.09.27 CN (85) PCT International Application Entering National Phase Date 2026.03.23 (86) PCT International Application Application Data PCT / CN2024 / 120409 2024.09.23 (87) PCT International Application Publication Data WO2025 / 067111 ZH 2025.04.03 (71) Applicant Suzhou Biyang Pharmaceutical Technology Co., Ltd. Address 215127 Unit E814, 5th Floor, Lecheng Plaza, Phase II, Biomedical Industrial Park, Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone, Suzhou City, Jiangsu Province (72) Inventors: Hu Qiyue, Hu Weimin, Liu Suxing (74) Patent Agency: Beijing Linke Intellectual Property Agency (Special General Partnership) 11690 Patent Attorneys: Wang Lihong, Zhang Dan (51) Int.Cl. C07D 487 / 04 (2006.01) C07D 471 / 04 (2006.01) A61K 31 / 537 (2006.01) A61K 31 / 519 (2006.01) A61P 35 / 00 (2006.01) A61P 3 / 10 (2006.01) A61P 37 / 02 (2006.01) (54) Invention Title: A Menin-MLL Interaction Inhibitor, Its Preparation Method and Application (57) Abstract: This invention discloses a Menin-MLL interaction inhibitor, its preparation method and application. The compound is expected to be used in the treatment of diseases mediated by Menin-MLL interaction, such as tumors and diabetes. CN 121969626 A 2026.05.01 CN 1 21 96 96 26 A