Tumor electric field therapy system and electrode patch thereof

Abstract

The invention provides a tumor electric field treatment system and an electrode patch thereof, the electrode patch is provided with an electrode array, and the electrode array comprises a plurality of electrode units arranged at intervals and a plurality of connecting parts located between the electrode units and connecting two adjacent electrode units. The electrode units are arranged in at least three rows and three columns, every two adjacent electrode units in at least two rows and each column are connected through a connecting part, and every two adjacent electrode units in at least two columns and each column are connected through a connecting part; every two adjacent electrode units in each column are arranged in a disconnected mode, and the electrode units arranged in the disconnected mode are all located on the periphery of the electrode array so that the relative positions of the two adjacent electrode units arranged in the disconnected mode can be freely adjusted in the column direction. At least part of the peripheral electrode units in the electrode patch of the tumor electric field treatment system are arranged in the disconnected mode in the column direction, so that the relative positions of the peripheral electrode units in the column direction can be freely adjusted when the electrode patch is pasted, and the electrode patch is prevented from generating wrinkles.

Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202410748951.0 (22) Application Date 2024.06.11 (71) Applicant Jiangsu Hailai Xinchuang Medical Technology Co., Ltd. Address 214174, 7th Floor, Building 7, No. 1699, Huishan Avenue, Huishan Economic Development Zone, Wuxi City, Jiangsu Province (72) Inventors Chen Sheng, Hui Jiajie, Yu Jing (74) Patent Agency Beijing Bosijia Intellectual Property Agency Co., Ltd. 11415 Patent Attorney Wang Jian (51) Int.Cl. A61N 1 / 36 (2006.01) A61N 1 / 04 (2006.01) (54) Invention Title: Tumor Electric Field Therapy System and Electrode Patch Thereof (57) Abstract: This application provides a tumor electric field therapy system and its electrode patch. The electrode patch has an electrode array, which includes a plurality of electrode units arranged at intervals and a plurality of connecting portions located between the electrode units and connecting adjacent electrode units. The electrode units are arranged in at least three rows and three columns. In at least two rows, adjacent electrode units are connected by a connecting portion, and in at least two columns, adjacent electrode units are connected by a connecting portion. In at least two columns, adjacent electrode units are disconnected from each other, and the disconnected electrode units are located on the periphery of the electrode array so that the relative positions of the disconnected adjacent electrode units in the column direction can be freely adjusted. In the electrode patch of the tumor electric field therapy system of this application, at least some of the peripheral electrode units are disconnected in the column direction, so that the relative positions of the peripheral electrode units in the column direction can be freely adjusted when the electrode patch is applied, avoiding wrinkles in the electrode patch. Claims 2 pages, Description 15 pages, Drawings 12 pages, CN 121102722 A 2025.12.12 CN 1 21 10 27 22 A 1. An electrode patch having an electrode array for applying an alternating current signal, the electrode array comprising a plurality of spaced-apart electrode units and a plurality of connecting portions located between the electrode units and connecting adjacent electrode units, characterized in that the electrode units are arranged in at least three rows and three columns, at least two rows are connected to adjacent electrode units by a connecting portion, at least two columns are connected to adjacent electrode units by a connecting portion; at least two columns are disconnected from adjacent electrode units and the disconnected electrode units are located on the periphery of the electrode array so that the relative positions of the disconnected adjacent electrode units in the column direction can be freely adjusted. 2. The electrode patch according to claim 1, characterized in that: the electrode units are distributed in a region of four rows and six columns, and the electrode units disconnected in the column direction are located in the first column and the sixth column respectively.3. The electrode patch according to claim 2, characterized in that: the electrode units arranged in a column-disconnected manner are respectively located in the second column and the fifth column, each electrode unit connected to adjacent two electrode units in each column by a connecting portion is located in the third column and the fourth column, and each adjacent two electrode units in each row are connected by a connecting portion. 4. The electrode patch according to claim 2, characterized in that: each adjacent two electrode units in each of the four middle columns are connected by a connecting portion, and each electrode unit connected to adjacent two electrode units in each row by a connecting portion is located in the first row and the fourth row. 5. The electrode patch according to claim 4, characterized in that: each adjacent two electrode units located in the four middle columns and the second row are arranged in a disconnected manner in the row direction. 6. The electrode patch according to claim 5, characterized in that: each adjacent two electrode units located in the four middle columns and the third row are arranged in a disconnected manner in the row direction. 7. The electrode patch according to any one of claims 3 to 6, characterized in that: the electrode array comprises 20 electrode units, the 20 electrode units are arranged in a manner where 4 are arranged in each of the first and fourth rows and are aligned in the column direction, and 6 are arranged in each of the second and third rows and are aligned in the column direction; the 4 electrode units in each of the first and fourth rows are respectively located in the middle four columns. 8. The electrode patch according to claim 1, characterized in that: a plurality of electrode units are divided into a plurality of electrode unit groups in pairs, the plurality of electrode unit groups are divided into an outer electrode unit group located around the electrode array and a central electrode unit group surrounded by the outer electrode unit groups, the central electrode unit group being located in the middle of the electrode array. 9. The electrode patch according to claim 8, characterized in that: each electrode unit group comprises two adjacent electrode units and a connecting portion connecting the two adjacent electrode units, the electrode array having a dielectric layer laid with respect to the electrode unit group. 10. The electrode patch according to claim 9, wherein the dielectric layer is disposed in a discontinuous manner between each of the electrode unit groups. 11. The electrode patch according to claim 9, wherein the electrode array further comprises an alloy layer laid with respect to the electrode unit groups, the alloy layer being disposed on the corresponding dielectric layer. 12. The electrode patch according to claim 9, wherein each electrode unit in each of the electrode unit groups comprises a main body, a conductive sheet disposed on the main body, and an insulating layer disposed on the main body and allowing the conductive sheet to be exposed, the portion of the conductive sheet exposed in the insulating layer being in direct contact with the dielectric layer for conduction. 13. The electrode patch according to claim 12, wherein each of the electrode unit groups connects two adjacent claims 1 / 2 page 2.CN 121102722 A The connecting portion of the electrode unit includes a connecting strip connected to the corresponding main body, AC lines spaced apart on the connecting strip, and an insulating strip on the connecting strip that allows the AC lines to be exposed. The dielectric layer of the AC lines directly contacts and conducts electricity, and electrically connects the conductive sheets of two adjacent electrode units in each electrode unit group located on their respective main bodies. 14. The electrode patch according to claim 12, characterized in that: the connecting portion connecting two adjacent electrode units in two adjacent electrode unit groups includes a connecting strip connected to the corresponding main body, AC lines spaced apart on the connecting strip, a grounding wire on the connecting strip located between the spaced AC lines, and an insulating layer on the connecting strip that covers the AC lines and the grounding wire. 15. The electrode patch according to claim 12, characterized in that: the connecting portion connecting two adjacent electrode units in two adjacent electrode unit groups includes a connecting strip connected to the corresponding main body, AC lines spaced apart on the connecting strip, and an insulating strip on the connecting strip that covers the AC lines. 16. The electrode patch according to any one of claims 9 to 15, characterized in that: the dielectric layer is made of a polymer having a dielectric constant of not less than 20. 17. The electrode patch according to claim 8, characterized in that: the electrode array further includes a plurality of temperature sensors respectively disposed on a corresponding electrode unit of a corresponding peripheral electrode unit group. 18. The electrode patch according to claim 17, characterized in that: each of the temperature sensors is disposed on an electrode unit in a corresponding peripheral electrode unit group near the center of the electrode array. 19. The electrode patch according to claim 8, characterized in that: at least some adjacent peripheral electrode unit groups have a variable spacing in the column direction. 20. A tumor electric field therapy system, characterized in that: it includes the electrode patch according to any one of claims 1 to 19. Claims 2 / 2 Page 3 CN 121102722 A Tumor Electric Field Therapy System and Electrode Patch Technical Field

[0001] This application relates to a tumor electric field therapy system and its electrode patch. Background Art

[0002] Intermediate frequency alternating electric field therapy has been proven to be an effective method for tumor treatment, capable of interfering with the mitotic process of cancer cells and inducing apoptosis of cancer cells, and can be used to treat tumors. Tumor electric field therapy systems typically include an electric field generator, an adapter, and multiple pairs of electrode patches. The electric field generator generates an alternating electric signal, which is transmitted to the electrode patches via the adapter. The electrode patches are applied in pairs to the surfaces of opposite sides of the patient's skin, and an alternating current signal is applied between each pair of electrode patches to non-invasively apply a tumor treatment electric field to the target area.

[0003] Chinese Invention Patent Application Publication No. 114099958 discloses an electrode patch, which includesThe electrode array includes a flexible circuit board and twenty electrode units spaced apart on the flexible circuit board. Adjacent electrode units are connected to each other via connecting parts. When the electrode patch is applied to the patient's abdomen or waist, the adjacent electrode units may be restrained and pulled by each other through the connecting parts as the patient moves, potentially leading to wrinkling of the electrode array edges, electrode units detaching from the body, or even the entire electrode patch falling off.

[0004] Therefore, improvements are needed to the existing tumor electric field therapy system and its electrode patch. Summary of the Invention

[0005] This application provides a tumor electric field therapy system and its electrode patch, in which at least some of the peripheral electrode units can be freely adjusted in relative position along the column direction during application.

[0006] Specifically, this application is achieved through the following technical solution: an electrode patch having an electrode array for applying an alternating current signal, the electrode array including a plurality of electrode units arranged at intervals and a plurality of connecting portions located between the electrode units and connecting adjacent electrode units, the electrode units being arranged in at least three rows and three columns, with adjacent electrode units in at least two rows connected by a connecting portion, and adjacent electrode units in at least two columns connected by a connecting portion; adjacent electrode units in at least two columns are disconnected from each other and the disconnected electrode units are located on the periphery of the electrode array so that the relative positions of the disconnected adjacent electrode units in the column direction can be freely adjusted.

[0007] Further, the electrode units are distributed in a region of four rows and six columns, and the electrode units arranged in a disconnected column direction are located in the first column and the sixth column, respectively.

[0008] Further, the electrode units arranged in a column-disconnected manner are also located in the second and fifth columns, and the electrode units connected to adjacent electrode units in each column by a connecting part are located in the third and fourth columns, respectively. Adjacent electrode units in each row are connected by a connecting part.

[0009] Further, adjacent electrode units in each of the four middle columns are connected by a connecting part, and the electrode units connected to adjacent electrode units in each row by a connecting part are located in the first and fourth rows, respectively.

[0010] Further, adjacent electrode units located in the four middle columns and in the second row are arranged in a disconnected manner in the row direction. Specification 1 / 15 page 4 CN 121102722 A

[0011] Further, adjacent electrode units located in the four middle columns and in the third row are arranged in a disconnected manner in the row direction.

[0012] Further, the electrode array includes 20 electrode units, wherein the 20 electrode units are arranged in a column-aligned manner with 4 units in each of the first and fourth rows, and 6 units in each of the second and third rows.Arrangement: The four electrode units in each of the first and fourth rows are located in the middle four columns.

[0013] Further, the electrode units are divided into several electrode unit groups in pairs, and the electrode unit groups are divided into peripheral electrode unit groups located around the electrode array and central electrode unit groups surrounded by the peripheral electrode unit groups, with the central electrode unit group located in the middle of the electrode array.

[0014] Further, each electrode unit group includes two adjacent electrode units and a connecting portion connecting the two adjacent electrode units, and the electrode array has a dielectric layer laid with respect to the electrode unit groups.

[0015] Further, the dielectric layer is disposed in a discontinuous manner between each electrode unit group.

[0016] Further, the electrode array also includes an alloy layer laid with respect to the electrode unit groups, and the alloy layer is disposed on the corresponding dielectric layer.

[0017] Further, each electrode unit in each electrode unit group includes a main body, a conductive sheet disposed on the main body, and an insulating layer disposed on the main body that allows the conductive sheet to be exposed. The portion of the conductive sheet exposed on the insulating layer is in direct contact with the dielectric layer and is electrically connected.

[0018] Further, the connecting portion connecting two adjacent electrode units in each electrode unit group includes a connecting strip connected to the corresponding main body, an AC line spaced apart on the connecting strip, and an insulating strip disposed on the connecting strip that allows the AC line to be exposed. The AC line is in direct contact with the dielectric layer and electrically connects the conductive sheets of the two adjacent electrode units in each electrode unit group located on their respective main bodies.

[0019] Further, the connecting portion connecting two adjacent electrode units in two adjacent electrode unit groups includes a connecting strip connected to the corresponding main body, an AC line spaced apart on the connecting strip, a grounding wire disposed on the connecting strip and located between the spaced AC lines, and an insulating layer disposed on the connecting strip and covering the AC line and the grounding wire.

[0020] Further, the connecting portion connecting two adjacent electrode units in two adjacent electrode unit groups includes a connecting strip connected to the corresponding main body, an AC line spaced apart on the connecting strip, and an insulating strip on the connecting strip covering the AC line.

[0021] Further, the dielectric layer is made of a polymer and has a dielectric constant of not less than 20.

[0022] Further, the electrode array also includes a plurality of temperature sensors respectively disposed on a corresponding electrode unit of a corresponding peripheral electrode unit group.

[0023] Further, each temperature sensor is disposed on an electrode unit in a corresponding peripheral electrode unit group near the center of the electrode array.

[0024] Further, at least some adjacent peripheral electrode unit groups have a variable spacing in the column direction.

[0025] This application also provides another technical solution: a tumor electric field therapy system, which includes the aforementioned electrode patch.

[0026] In the tumor electric field therapy system and its electrode patch of this application, at least some of the peripheral electrode units are arranged in a disconnected manner in the column direction, so that the relative positions of the peripheral electrode units in the column direction can be freely adjusted when the electrode patch is applied, avoiding wrinkles and edge lifting of the electrode patch.

[0027] It should be understood that the above general description and the following detailed description are exemplary and explanatory only, and do not limit this application.

[0028] FIG1 is a framework diagram of a tumor electric field therapy system according to one embodiment of the present application;

[0029] FIG2 is a plan view of an electrode patch according to one embodiment of the present application;

[0030] FIG3 is a plan view of a first embodiment of the electrode array of the electrode patch in FIG2;

[0031] FIG4 is similar to FIG3, except that dashed lines are added to indicate each electrode unit group;

[0032] FIG5 is a wiring diagram of the grounding wire of the electrode array in FIG3, wherein the insulating layer, dielectric layer, and alloy layer are removed, and the AC line is not shown;

[0033] FIG6 is a wiring diagram of the temperature measuring wire of the electrode array in FIG3, wherein the covering film is removed;

[0034] FIG7 is a wiring diagram of the AC line of the electrode array in FIG3, wherein the insulating layer, dielectric layer, and alloy layer are removed, and the grounding wire is not shown;

[0035] FIG8 is another plan view of the electrode array shown in FIG3, wherein the dielectric layer and alloy layer are removed;

[0036] FIG9 is a partial enlarged view of point A in FIG8;

[0037] FIG10 is a cross-sectional view taken along the B-B direction of FIG3;

[0038] FIG11 is a cross-sectional view taken along the C-C direction of FIG3;

[0039] FIG12 is a cross-sectional view taken along the D-D direction of FIG3;

[0040] FIG13 is a cross-sectional view taken along the E-E direction of FIG3;

[0041] FIG14 is a plan view of a second embodiment of the electrode array according to the present application;

[0042] FIG15 is another plan view of the electrode array shown in FIG14, wherein the dielectric layer and alloy layer are removed;

[0043] FIG16 is a wiring diagram of the AC line and ground line of the electrode array shown in FIG14, wherein the dielectric layer, alloy layer, and temperature sensor are removed, and the conductive traces under the insulating layer are shown as dashed lines;

[0044] FIG17 is a wiring diagram of the temperature measuring line of the electrode array shown in FIG14, wherein the covering film is removed.

[0045] Explanation of reference numerals:

[0046] Tumor electric field therapy system 100, electric field generator 10, adapter 20, electrode patch 30, backing 31, ventilation hole311, Notch 312, Electrode arrays 32, 32', Temperature sensor 321, 321', Ground terminal 3211, Signal terminal 3212, Lead wire 3213, Connecting part 322, 322', Meridional connecting part 3221, 3221', First meridional connecting part 3221A, Second meridional connecting part 3221B, Third warp connector 3221C, weft connectors 3222, 3222', first weft connectors 3222A, 3222A', second weft connectors 3222B, 3222B', third weft connector 3222C, wiring parts 323, 323', gold fingers 3231, 3231', first open space 301, second open space 302, third open space 303, fourth open space 304, fifth open space 305, sixth open space 306, open spaces 307, 308, 309, substrate 325, 325', main body 3250, 3250', connecting strip 3251. 3251', Grounding wire 3252, 3252', Temperature measuring wire 3253, 3253', AC wire 3254, 3254', First wiring trough 3256, Reinforcing plate 326, Adhesive piece 33, Main adhesive part 331, Connecting strip 332, Notch 333, Electrode unit 320, 320', C1-C20, C1'-C20', Conductive sheet 342, 342', Opening 3421, Sealant 343, Grounding pad 344, 344', Signal pad 345, 345', Insulating layer 346, 346', First insulating layer 3461, Second insulating layer 3462, Insulating strip 3463, Inner insulating strip 3464, Outer insulating strip 3465, Dielectric layer 347, Alloy layer 348, 348', Covering film 349, Heat dissipation hole 340. Detailed Description of Embodiments

[0047] Exemplary embodiments will now be described in detail, examples of which are illustrated in the accompanying drawings. When the following description refers to the specification page 3 / 15, 6 CN 121102722 A and the accompanying drawings, unless otherwise indicated, the same numbers in different drawings represent the same or similar elements. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with this application. Rather, they are merely examples of apparatuses, systems, devices, and methods consistent with some aspects of this application.

[0048] First Embodiment:

[0049] Referring to FIG1, a tumor electric field therapy system 100 includes an electric field generator 10, an adapter 20, and a plurality of paired electrode patches 30. The adapter 20 electrically connects the electric field generator 10 to each electrode patch 30. The electric field generator 10 generates an alternating current signal sufficient for treatment, and the adapter 20 receives the alternating current signal output from the electric field generator 10 and transmits the alternating current signal to the electrode patches 30. Electrode patches 30 are attached to the patient's body surface corresponding to the tumor area, and alternating current signals are applied to the patient's tumor area to perform tumor electric field therapy.

[0050] Referring to Figures 2 and 3, the electrode patch 30 includes a backing 31, an electrode array 32 attached to the front of the backing 31, and multiple adhesive pieces 33 attached to the front of the electrode array 32. The front of the backing 31, the electrode array 32, and the adhesive pieces 33 all face the patient's skin. The electrode array 32 includes twenty electrode units 320 spaced apart and eight temperature sensors 321 selectively disposed on eight of the electrode units 320. The electrode units 320 apply an alternating current signal to the patient, and the temperature sensors 321 can provide feedback on the temperature of the corresponding electrode unit 320 at the point of application to the body surface, preventing heat generated on the electrode units 320 during the application of the alternating current signal from causing burns to the patient's skin. The adhesive patch 33 is sheet-shaped and covers each electrode unit 320. During use, it is attached to the patient's tumor-corresponding body surface. The adhesive patch 33 is a conductive hydrogel, which can enhance the comfort of the electrode unit 320 to the patient's body surface. At the same time, it can also serve as a conductive medium to allow the alternating current signal passing through the electrode unit 320 to be applied to the patient's tumor site.

[0051] The electrode array 32 includes a connecting portion 322 connecting two adjacent electrode units 320 and a wiring portion 323 extending outward from one of the connecting portions 322. The wiring portion 323 is soldered to or detachably connected to a wire (not shown). The wire (not shown) is used to electrically connect the electrode patch 30 to the adapter 20 to receive the alternating current signal from the electric field generator 10 and transmit the detection signal of each temperature sensor 321 to the electric field generator 10. The wiring section 323 is provided with a plurality of gold fingers 3231, which are respectively arranged on the front and back sides of the wiring section 323 to reduce the width of the wiring section 323. A reasonable spacing is provided between each gold finger 3231 to avoid short circuits or signal coupling problems caused by adjacent gold fingers 3231 being too close.

[0052] The twenty electrode units 320 are arranged in an array of approximately four rows and six columns. The first and fourth rows each have four electrode units 320, and the second and third rows each have six electrode units 320. The six electrode units 320 in each of the second and third rows correspond one-to-one and are arranged in approximately six columns. The four electrode units 320 in each of the first and fourth rows are located in the middle four columns. From left to right, the four electrode units 320 in the first row are defined as C1, C2, C3, and C4; the six electrode units 320 in the second row are defined as C5, C6, C7, C8, C9, and C10; the six electrode units 320 in the third row are defined as C11, C12, C13, C14, C15, and C16; and the four electrode units 320 in the fourth row are defined as C17, C18, C19, and C20. The multiple electrode units 320 located in the same row are not distributed in a straight line, but rather roughly in an arc shape. The electrodes located in the first and second rows...The units 320 are all distributed on the arcs that curve upwards at both ends. The electrode units 320 in the third and fourth rows are all distributed on the arcs that curve downwards at both ends. Specifically, the arcs of the electrode units 320 in the first and fourth rows are arcs with a radius of about 193 mm and an arc length of about 95 mm to 105 mm, with the arc length preferably being 101 mm; the arcs of the electrode units 320 in the second and third rows are arcs with a radius of about 363 mm and an arc length of about 155 mm to 165 mm, with the arc length preferably being 160 mm. This shape design makes the electrode array 32 more suitable for application to the waist, which can improve the adhesion of the electrode patch 30 and avoid wrinkling during application.

[0053] Referring to Figure 4, two adjacent electrode units 320 in each row form an electrode unit group. These twenty electrode units form an electrode unit group. The electrode unit 320 forms a total of 10 electrode unit groups, namely: a first electrode unit group formed by two electrode units C1 and C2 located in the first row and the connecting portion 322 between them; a second electrode unit group formed by two electrode units C3 and C4 located in the first row and the connecting portion 322 between them; a third electrode unit group formed by two electrode units C5 and C6 located in the second row and the connecting portion 322 between them; a fourth electrode unit group formed by two electrode units C7 and C8 located in the second row and the connecting portion 322 between them; and a fifth electrode unit group formed by two electrode units C9 and C10 located in the second row and the connecting portion 322 between them. The fifth electrode unit group, the sixth electrode unit group formed by the two electrode units C11 and C12 in the third row and the connecting part 322 between them, the seventh electrode unit group formed by the two electrode units C13 and C14 in the third row and the connecting part 322 between them, the eighth electrode unit group formed by the two electrode units C15 and C16 in the third row and the connecting part 322 between them, the ninth electrode unit group formed by the two electrode units C17 and C18 in the fourth row and the connecting part 322 between them, and the tenth electrode unit group formed by the two electrode units C19 and C20 in the fourth row and the connecting part 322 between them.

[0054] As shown in FIG2, there are ten adhesive pieces 33 in total, which are respectively attached to each electrode unit group. The shape of the adhesive patch 33 is roughly the same as that of the electrode unit group, but its size is slightly larger than that of the electrode unit group. The adhesive patch 33 is roughly dumbbell-shaped and includes two main adhesive portions 331 and a connecting strip 332 connecting the two main adhesive portions 331. The main adhesive portions 331 cover the corresponding electrode units 320 in the corresponding electrode unit group, and the connecting strip 332 covers the connecting portion 322 in the electrode unit group. The positions of the two electrode units 320 in the electrode unit group are basically fixed relative to each other during the application of the electrode patch 30.No significant relative displacement occurs, so the adhesive patch 33 can be reliably fixed to the corresponding electrode unit group without slippage. Specifically, since only the adjacent electrode units 320 in the third and fourth columns have a radial connection 3221, while the adjacent electrode units 320 in the first, second, fifth, and sixth columns are disconnected and do not have any radial connection 3221, the electrode units 320 (C1, C4, C5, C10, C11, C16, C17, C20) located at the left and right ends (i.e., the periphery) in each row have a certain degree of freedom in the radial direction (i.e., the column direction). During application, the position can be adjusted appropriately according to the patient's needs, preventing the electrode units 320 around the electrode array 32 from lifting up and affecting the application of the electrode patch 30. In addition, a notch 333 is formed between the two main adhesive parts 331 and the connecting strip 332. The notch 333 reduces the area of ​​the adhesive part 33, thereby increasing the breathability of the electrode patch 30.

[0055] The electrode patch 30 is applied with its front side facing the patient. The part of the backing 31 not covered by the electrode array 32 and the adhesive part 33 is applied to the patient's body surface. The backing 31 is usually made of breathable materials such as textiles, non-woven fabrics, and microporous membranes. The shape of the backing 31 is roughly similar to the overall outer contour of the electrode array 32, but the area of ​​the backing 31 is larger than the area of ​​the overall outer contour of the electrode array 32. Several ventilation holes 311 for heat dissipation, perspiration, and breathability are provided on the backing 31. In this embodiment, the backing 31 has three ventilation holes 311 between the electrode units 320 in the first row and the electrode units 320 in the second row; and three ventilation holes 311 are also provided between the electrode units 320 in the third row and the electrode units 320 in the fourth row, so as to facilitate heat dissipation and perspiration on the patient's body surface where the electrode patch 30 is applied. The edge of the backing 31 is also provided with a notch 312 to avoid the connection part 323, so as to avoid the heat shrink sleeve (not shown) that is sleeved at the junction of the connection part 323 and the wire (not shown) after welding or electrical connection, so as to make the electrode patch 30 applied more smoothly.

[0056] The electrode array 32 will be described below from the perspective of the spatial arrangement of the electrode units 320.

[0057] Referring to Figures 3 and 4, the electrode array 32 includes several connecting portions 322, including the aforementioned longitudinal connecting portions 3221 extending along the longitude direction (i.e., column-up) and latitudinal connecting portions 3222 extending along the latitude direction (i.e., row-up). Any two adjacent electrode units 320 located in the third column are connected by a longitudinal connecting portion 3221, and any two adjacent electrode units 320 located in the fourth column are also connected by a longitudinal connecting portion 3221. Adjacent electrode units 320 located in other columns are disconnected, meaning no longitudinal connecting portion 3221 is provided. Specifically, in columns other than the third and fourth columns...The electrode units 320 in the other columns of the four columns are free in the longitude direction and have a certain range of free movement. Any two adjacent electrode units 320 located on page 5 / 15 of the specification, row 8 CN 121102722 A, are connected by a latitudinal connecting part 3222, wherein the wiring part 323 extends outward from the latitudinal connecting part 3222 located in the middle of the fourth row. Since adjacent electrode units 320 in the first, second, fifth, and sixth columns are disconnected and spaced apart, and adjacent electrode units 320 in the third and fourth columns are also spaced apart but connected by a warp connection 3221, these twenty electrode units 320 form several open spaces 301, 302, 303, 304, 305, and 306 on the periphery. Specifically, the first open space 301 is formed by electrode units C1, C2, C5, C6, and C7, and the warp connection 3221 and weft connection 3222 between these five electrode units 320; the second open space 302 is formed by electrode units C3, C4, C8, C9, and C10, and the warp connection 3221 and weft connection 3222 between these five electrode units 320; and the third open space 302 is formed by electrode unit C5, C6, C7, C8, C9, C10 ... The third open space 303 is formed by C6, C7, C11, C12, C13 and the warp connection 3221 and the weft connection 3222 located between the five electrode units 320. The fourth open space 304 is formed by electrode units C8, C9, C10, C14, C15, C16 and the warp connection 3221 and the weft connection 3222 located between the five electrode units 320. The fifth open space 305 is formed by electrode units C11, C12, C13, C17, C18 and the warp connection 3221 and the weft connection 3222 located between the five electrode units 320. The sixth open space 306 is formed by electrode units C14, C15, C16, C19, C20 and the warp connection 3221 and the weft connection 3222 located between the five electrode units 320. Each open space 301, 302, 303, 304, 305, and 306 is connected to the external space in the direction of the electrode array 32's application surface. The electrode units C2, C3, C7, C8, C13, C14, C18, and C19 on each of the second and third columns of the electrode array 32 are also arranged at intervals, so that the open spaces 307, 308, and 309 in the middle are formed by the four electrode units 320 located in adjacent rows and adjacent columns, and the latitudinal connecting parts 3222 and the longitudinal connecting parts 3221 located between adjacent electrode units 320.

[0058] The plurality of radial connecting portions 3221 include a first radial connecting portion 3221A connecting two adjacent electrode units 320 in the first and second rows, a second radial connecting portion 3221B connecting two adjacent electrode units 320 in the second and third rows, and a third radial connecting portion 3221C connecting two adjacent electrode units 320 in the third and fourth rows. The lengths of the first radial connecting portion 3221A and the third radial connecting portion 3221C are equal, but both are longer than the length of the second radial connecting portion 3221B. The plurality of latitudinal connecting portions 3222 include a plurality of first latitudinal connecting portions 3222A, a plurality of second latitudinal connecting portions 3222B, and a plurality of third latitudinal connecting portions 3222C. The first latitudinal connecting portions 3222A connect two electrode units 320 within each electrode unit group. The second latitudinal connecting portions 3222B are connecting portions 322 between adjacent electrode units C2 and C3 in the first electrode unit group and the second electrode unit group, and between adjacent electrode units C18 and C19 in the ninth electrode unit group and the tenth electrode unit group. The third latitudinal connecting portions 3222C are connecting portions 322 between adjacent electrode units C6 and C7 in the third electrode unit group and the fourth electrode unit group, between adjacent electrode units C8 and C9 in the fourth electrode unit group and the fifth electrode unit group, between adjacent electrode units C12 and C13 in the sixth electrode unit group and the seventh electrode unit group, and between adjacent electrode units C14 and C15 in the seventh electrode unit group and the eighth electrode unit group. The lengths of the first latitudinal connecting portion 3222A and the second latitudinal connecting portion 3222B are equal, but both are longer than the length of the third latitudinal connecting portion 3222C.

[0059] Among the ten electrode unit groups of the electrode patch 30, the fourth electrode unit group and the seventh electrode unit group are located at the center of the electrode array 32 and are defined as the central electrode unit group; the other eight electrode unit groups are arranged around the periphery of the central electrode unit group and are defined as the peripheral electrode unit groups. The electrical properties and heating conditions of the two electrode units 320 in each electrode unit group are consistent, so the temperature changes are also basically consistent, and the specific reasons will be explained in detail later. In order to comprehensively detect the temperature of each electrode unit 320 in the electrode patch 30, the eight temperature sensors 321 of the electrode patch 30 are respectively arranged in the eight peripheral electrode unit groups. Specifically, the temperature sensors 321 distributed in the corresponding peripheral electrode unit groups are all arranged on an electrode unit 320 closer to the center of the electrode array 32 in each electrode unit group, so that each temperature sensor 321 is closer to the central electrode unit group, that is, the temperature sensors 321 are arranged around the fourth electrode unit group and the seventh electrode unit group. Because they are connected to the fourth electrode unit group...The lengths of the third latitudinal connecting portions 3222C on each of the electrode units C7, C8, C13, and C14 in the seventh electrode unit group are relatively short. Therefore, the temperature at electrode unit C7 is close to the temperature at electrode unit C6, the temperature at electrode unit C8 is close to the temperature at electrode unit C9, the temperature at electrode unit C13 is close to the temperature at electrode unit C12, and the temperature at electrode unit C14 is close to the temperature at electrode unit C15. Thus, by placing these eight temperature sensors 321 on electrode units C2, C3, C6, C9, C12, C15, C18, and C19 respectively, the temperature of each peripheral electrode unit group can be directly monitored. The temperature at the fourth electrode unit group can be referenced to the temperature of the third or fifth electrode unit group, and the temperature at the seventh electrode unit group can be referenced to the temperature of the sixth or eighth electrode unit group. With this reasonable arrangement, only eight temperature sensors 321 are needed to monitor the temperature of all twenty electrode units 320, improving temperature detection efficiency and reducing wiring complexity. It is understood that the central electrode unit group can also be replaced by a single central electrode unit, and the temperature of the central electrode unit can be referenced to the temperature of the peripheral electrode unit group next to it.

[0060] The electrode array 32 will be described below from the perspective of the manufacturing process of the electrode array 32. Referring to FIG5, the electrode array 32 includes a flexible substrate 325 arranged in a sheet shape. The substrate 325 serves as a supporting base plate and is integrally disposed in each electrode unit 320, each connecting part 322, and the wiring part 323. Each electrode unit 320, each connecting part 322, and the wiring part 323 are further provided with other structures on the front and / or bottom surfaces of the substrate 325, which will be described in detail later. The thickness of the substrate 325 is 0.1mm-0.3mm, and its material is polyimide or polyester film, which has the characteristics of light weight, thin thickness, bendability, and high flexibility. For ease of description, the portion of the substrate 325 corresponding to each electrode unit 320 is defined as the main body 3250, and the portion of the substrate 325 corresponding to each connecting portion 322 and wiring portion 323 is defined as the connecting strip 3251. Each main body 3250 and each connecting strip 3251 are different parts of the entire substrate 325. The main body 3250 is arranged in a circular sheet shape. The electrode unit 320 has a conductive sheet 342 on the main body 3250. The conductive sheet 342 is arranged in a ring shape with a through hole 3421 at its center. The thickness of the conductive sheet 342 is 10μm to 50μm. The conductive sheet 342 is concentrically arranged with the main body 3250, and the outer contour of the conductive sheet 342 is smaller than the outer contour of the main body 3250.

[0061] Referring to FIG11, the opening 3421 of the conductive sheet 342 exposes the front side of the corresponding main body 3250. The temperature sensor 321 is placed in the opening 3421 of the conductive sheet 342 of the corresponding electrode unit 320 and fixed to the main body 3250. The electrode unit 320The temperature sensor 321 is further encapsulated within the opening 3421 of the conductive sheet 342 using sealant 343. The temperature sensor 321 can be a thermistor with a negative temperature coefficient. The sealant 343 can be a curing agent with a low coefficient of expansion, low water absorption, and low flowability to prevent overflow during application and ensure it doesn't affect the surface smoothness of the conductive sheet 342. The sealant 343 can be a curing sealant with low flowability and biocompatibility, and is cured at high temperature or with light of a specific wavelength. The cured sealant 343 exhibits excellent shock resistance and resistance to electrical corrosion; modified epoxy resin is preferred as its material.

[0062] The main body 3250 of the electrode unit 320 has grounding pads 344 and signal pads 345 spaced apart within the openings 3421 of the conductive sheet 342. The bottom surface of the temperature sensor 321 has a grounding terminal 3211, and the top surface of the temperature sensor 321 has a signal terminal 3212. The grounding terminal 3211 is soldered to the corresponding grounding pad 344, and the signal terminal 3212 is electrically connected to the corresponding signal pad 345 through a lead 3213. Optionally, the electrode unit 320 has a reinforcing plate 326 on the back of the main body 3250 at the position corresponding to the temperature sensor 321. The reinforcing plate 326 can support the main body 3250, making it convenient for the temperature sensor 321 to be mounted on the main body 3250 using a surface mount process. The reinforcing plate 326 is preferably polyimide, with a thickness not exceeding 100 μm and a projected area not less than the projected area of ​​the temperature sensor 321. The reinforcing plate 326 is not mandatory; the structure can also be reinforced by appropriately increasing the thickness of the main body 3250 (i.e., the substrate 325).

[0063] Referring to Figures 5 to 7, the electrode array 32 has several conductive traces (unlabeled) arranged on the substrate 325. The conductive traces (unlabeled) include a grounding wire 3252 for transmitting grounding signals, eight temperature measuring wires 3253 for transmitting DC signals, and several AC lines 3254 for transmitting AC signals. The grounding wire 3252 is used to electrically connect to all grounding pads 344, and the several temperature measuring wires 3253 are electrically connected to each signal pad 345 respectively. Several AC lines 3254 are electrically connected to each conductive piece 342 of each electrode unit 320 to transmit AC signals to each electrode unit 320. The aforementioned wiring portion 323 has a total of eleven gold fingers 3231. One gold finger 3231 is connected to the grounding wire 3252; eight gold fingers 3231 are respectively connected to several temperature measuring wires 3253; one gold finger 3231 is connected to the AC line 3254; and the remaining gold finger 3231 is connected to the shielding layer (not shown) of the conductor (not shown) and grounded for electromagnetic shielding and to prevent signal interference.

[0064] Figure 5 shows only a schematic diagram of the grounding wire 3252's wiring on the substrate 325. The grounding wire 3252 is mainly distributed on the front side of the substrate 325. After being led out from a gold finger 3231 on the wiring part 323, the grounding wire 3252 is divided into multiple branches and extends along the corresponding longitudinal connection part 3221 and latitudinal connection part 3222, and is electrically connected to the grounding pads 344 located at the centers of the eight electrode units C2, C3, C6, C9, C12, C15, C18, and C19 on the substrate 325. The gold finger 3231 that conducts the grounding wire 3252 is also electrically connected to the gold finger 3231 that is electrically connected to the shielding layer (not shown), and both are located on the front side of the wiring part 323. Specifically, the grounding wire 3252 is led out from a gold finger 3231 of the wiring part 323 and extends along the wiring part 323 to the second latitudinal connection part 3222B between the two electrode units C18 and C19 in the third and fourth columns of the fourth row. Then, it branches along the left and right sides of the second latitudinal connection part 3222B to form a left branch and a right branch. The left branch extends to the center of electrode unit C18 and connects to the ground pad 344 of electrode unit C18. It then extends upward along the third column of electrode units 320, passing sequentially through the center of electrode unit C13 in the third row of the third column, the center of electrode unit C7 in the second row of the third column, and finally to the center of electrode unit C2 in the first row of the third column, where it connects to the ground pad 344 of electrode unit C2. The left branch also further branches to the left from the center of electrode unit C13 in the third row of the third column, extending to the center of electrode unit C12 in the second row of the third column and connecting to the ground pad 344 of electrode unit C12. The left branch also further branches to the left from the center of electrode unit C7 in the third row of the second column, extending to the center of electrode unit C6 in the second row of the second column and connecting to the ground pad 344 of electrode unit C6. The right branch extends to the center of electrode unit C19 and connects to the ground pad 344 of electrode unit C19. It then extends upwards along the column direction of the fourth column of electrode units 320, passing sequentially at the center of electrode unit C14 in the third row of the fourth column, and the center of electrode unit C8 in the second row of the fourth column, before reaching the center of electrode unit C3 in the first row of the fourth column and connecting to the ground pad 344 of electrode unit C3. The right branch further branches to the right from the center of electrode unit C14 in the fourth column of the third row, extending to the center of electrode unit C15 in the fifth column of the third row and connecting to the ground pad 344 of electrode unit C15. Similarly, the right branch further branches to the right from the center of electrode unit C8 in the fourth column of the second row, extending to the center of electrode unit C9 in the fifth column of the second row and connecting to the ground pad 344 of electrode unit C9. Using the above wiring method...In this configuration, the grounding wire 3252 led out from the wiring part 323 allows the grounding pads 344 of each temperature sensor 321 located on the eight electrode units C2, C3, C6, C9, C12, C15, C18, and C19 to be connected, simplifying the wiring.

[0065] Figure 6 shows a schematic diagram of the wiring of the temperature measuring wire 3253 on the substrate 325. The eight temperature measuring wires 3253 are distributed on the reverse side of the substrate 325. The eight temperature measuring wires 3253 are independent of each other and are led out from a corresponding gold finger 3231 on the wiring part 323. Each temperature sensing wire 3253 is led out from a corresponding gold finger 3231 of the wiring section 323 and extends sequentially along the column-row-column or column-row-column-row direction, passing through the corresponding electrode unit 320 and the corresponding connection section 322, respectively, to the center of one of the eight electrode units C2, C3, C6, C9, C12, C15, C18, and C19 where the temperature sensors 321 are installed. It then passes through the corresponding conductive via (not shown) of the through substrate 325 and is electrically connected to the corresponding signal pad 345 on the front side of the substrate 325. The overall distribution of the temperature sensing wires 3253 is basically similar to that of the ground wires 3252, and will not be described further. The eight gold fingers 3231 of the temperature sensing wires 3253 are located on both sides of the wiring section 323.

[0066] Figure 7 is a schematic diagram of the wiring of AC line 3254 on substrate 325. AC line 3254 is distributed on the front side of substrate 325, and the gold finger 3231 of AC line 3254 is located on the front side of connector 323. AC line 3254 is led out from one gold finger 3231 on connector 323 and divided into multiple segments. In this embodiment, each connector 322 is provided with a segment of AC line 3254 to electrically connect the conductive sheet 342 of two adjacent electrode units 320. Each AC line 3254 is interconnected through the conductive sheet 342 of each electrode unit 320. AC line 3254 is electrically connected to all conductive sheets 342 to transmit AC signal to all conductive sheets 342.

[0067] Referring to Figures 5 and 7, on the front side of the substrate 325, AC lines 3254 are arranged on each connection portion 322, and ground lines 3252 are arranged on some connection portions 322 and some main body portions 3250. Each main body portion 3250 is provided with a corresponding conductive sheet 342, and some main body portions 3250 are also provided with grounding pads 344 and signal pads 345. AC lines 3254, ground lines 3252 located on the front side of the substrate 325, conductive sheets 342, grounding pads 344 and signal pads 345 are located on the same layer, together constituting the conductive layer (unlabeled) located on the front side of the substrate 325.

[0068] Referring to Figures 8 and 9, after the conductive layer (unlabeled) is set, the electrode array 32 is on the substrate 325 and the conductive layer.An insulating layer 346 is laid on the substrate 325, partially covering the main body 3250 and the connecting part 322, and completely covering the wiring part 323, forming a solder mask layer on the substrate 325. The insulating layer 346 is laid on the front side of the substrate 325 using COB (Chip On Board) technology, and its thickness is 10μm to 50μm. The electrode array 32 also includes conductive sheets 342 without insulating layer 346 and dielectric layers 347 on the corresponding AC lines 3254 within the electrode unit groups, which are laid on the insulating layer 346 in units of electrode units. The insulating layer 346 also serves as a heat insulation layer, reducing the heat transfer from the conductive sheets 342 and the corresponding AC lines 3254 to the dielectric layer 347 laid on the insulating layer 346. Figure 8 shows a schematic diagram of the electrode array 32 after the insulating layer 346 is laid.

[0069] Specifically, the insulating layer 346 partially covers the main body 3250 and the first latitudinal connecting portion 3222A, and completely covers the AC line 3254 and grounding line 3252 located on the connecting strip 3251 of the second latitudinal connecting portion 3222B, the third latitudinal connecting portion 3222C, and the wiring portion 323. The insulating layer 346 on the main body 3250 is generally hub-shaped, including a circular first insulating layer 3461 at the center, an annular second insulating layer 3462 on the outer ring, and an insulating strip 3463 radially connecting the first insulating layer 3461 and the second insulating layer 3462. For the main body 3250 with ground pad 344 and signal pad 345, the first insulating layer 3461 needs to expose the ground pad 344 and signal pad 345 to accommodate the temperature sensor 321. Therefore, a portion of the first insulating layer 3461 has through holes (unlabeled) corresponding to the ground pad 344 and signal pad 345. The outer contour of the second insulating layer 3462 is the same as the outer contour of the main body 3250. The inner contour of the second insulating layer 3462 is slightly smaller than the outer contour of the conductive sheet 342, and the outer contour of the first insulating layer 3461 is slightly larger than the outer contour of the opening 3421 of the conductive sheet 342. The first insulating layer 3461 located at the center and the second insulating layer 3462 located on the outer ring are separated by four insulating strips 3463 to create four fan-shaped hollow areas (unlabeled) to expose the conductive sheet 342 located below the insulating layer 346, so that the conductive sheet 342 can directly contact and conduct with the dielectric layer 347 laid on it.

[0070] The insulating layer 346 on the first latitudinal connecting portion 3222A in each electrode unit group also partially covers its connecting strip 3251 to expose the corresponding AC wire 3254, and so that the connecting strip 3251 arranged on the first latitudinal connecting portion 3222A is exposed.The AC line 3254 can directly contact and conduct with the dielectric layer 347 laid on it. The insulating layer 346 on the first latitudinal connection portion 3222A within each electrode unit group includes an inner insulating strip 3464 located between the two AC lines 3254 and an outer insulating strip 3465 located outside the two AC lines 3254. The inner insulating strip 3464 is connected to the corresponding parts of the second insulating layer 3462 and the insulating tape 3463 located at its two ends, respectively. The two ends of the outer insulating strip 3465 are connected to the corresponding parts of the corresponding second insulating layer 3462 located on both sides of the insulating tape 3463 located at its two ends. The insulating layer 346 on the second latitudinal connection portion 3222B and the third latitudinal connection portion 3222C located between the various electrode unit groups is provided on the corresponding second latitudinal connection portion 3222B and the third latitudinal connection portion 3222C in such a way that it completely covers the grounding wire 3252 and the AC wire 3254 on the corresponding connection portion 322. Therefore, in Figure 8, some of the grounding wire 3252 and the AC wire 3254 are shown as dashed lines. The electrode unit 320 has a plurality of through heat dissipation holes 340 evenly provided on its outer periphery. The heat dissipation holes 340 are provided on the electrode unit 320, avoiding the connection between the electrode unit 320 and the corresponding connection portion 322. These heat dissipation holes 340 are arranged around the outside of the conductive sheet 342 and penetrate the substrate 325 and the insulating layer 346. The heat dissipation holes 340 are used for heat dissipation of the electrode unit 320.

[0071] Returning to Figure 3, the electrode array 32 in Figure 3 is in the state after the dielectric layer 347 is laid. The dielectric layer 347 is laid separately for each electrode unit group, that is, the dielectric layers 347 between each electrode unit group are disconnected. The dielectric layer 347 covers the insulating layer 346 of each electrode unit group, as well as the conductive sheet 342 and AC line 3254 that are not covered by the insulating layer 346. The dielectric layer 347 can completely cover the conductive sheet 342 to prevent the conductive sheet 342 from directly contacting the human body and generating direct current conduction, which would affect human safety. The edge of the dielectric layer 347 does not exceed the outer contour of the substrate 325 so that the dielectric layer 347 can be fully supported by the substrate 325. The dielectric layer 347 is a polymer dielectric layer with high dielectric constant and low dielectric loss, which is made of a thin film material with non-fixed crystal orientation, high flexibility and high toughness. In this embodiment, the dielectric layer 347 is made of a polymer with a dielectric constant of not less than 20 and a dielectric strength of not less than 40V / μm to prevent the dielectric layer 347 from being broken down under normal applied voltage. The polymer is a polymer with relaxor ferroelectric behavior, and can be a vinylidene fluoride polymer, such as P(VDF-TrFE-CTFE), P(VDF-TrFE-CFE), or P(VDF-TrFE-CFE-CTFE), or a polyamide composite material, such as piperazine-biuret.Copolymers such as polyamides are used. The dielectric layer 347 can be formed on the surfaces of the conductive sheet 342, the corresponding AC line 3254, and the corresponding portions of the insulating layer 346 by vapor deposition, sputtering, or ion plating vapor deposition. It can also be formed on the surfaces of the conductive sheet 342, the corresponding AC line 3254, and the corresponding portions of the insulating layer 346 by printing, spraying, or casting. The thickness of the dielectric layer 347 is 3μm-10μm. A corresponding dielectric layer 347 is also formed on the inner wall of the heat dissipation hole 340 to facilitate heat dissipation.

[0072] The dielectric layer 347 provided on the substrate 325 is divided into multiple spaced sub-regions because it is laid in the manner of electrode unit groups. The dielectric layer 347 in each sub-region is laid in a fully covered manner on the conductive sheet 342 of the main body portion 3250 of the two electrode units 320 located in the same electrode unit group and on the AC line 3254 on the connecting strip 3251 of the first latitudinal connecting portion 3222A located in the electrode unit group. The dielectric layer 347 within a single sub-region is laid out in a shape consistent with the outer contour of a single electrode unit group, directly covering the conductive sheets 342 of the two electrode units 320 within the corresponding electrode unit group and the AC line 3254 on the first latitudinal connection portion 3222A. The dielectric layer 347 in different sub-regions covers different electrode unit groups, and the dielectric layers 347 in different sub-regions are spaced apart. That is, the dielectric layer 347 is not provided on the second latitudinal connection portion 3222B, the third latitudinal connection portion 3222C, all the longitudinal connection portions 3221, and the wiring portion 323. The dielectric layer 347 simultaneously covers and conducts the conductive sheets 342 of the two electrode units 320 within the corresponding electrode unit group and the AC line 3254 between them, so that the two electrode units 320 within each electrode unit group can simultaneously apply AC signals. With this arrangement, the twenty electrode units 320 can be divided into ten groups of two, and the electrical performance parameters of each electrode unit group are the same, and AC signals can be transmitted in parallel. When performing electrical testing on the electrode patch 30, testing can be performed on a per-electrode-unit-group basis, improving testing efficiency.

[0073] The temperatures of the two electrode units 320 within the electrode unit group are basically the same because the AC lines 3254 of the two conductive sheets 342 connecting the two electrode units 320 are directly covered by the dielectric layer 347, allowing the two electrode units 320 to quickly transfer heat to each other, making their temperatures and changes basically the same. Therefore, the temperature measured by the temperature sensor 321 on one of the electrode units 320 in the same electrode unit group can represent the temperatures of the two electrode units 320 in the entire electrode unit group. When performing electrical testing on the electrode unit 320, testing can be performed on a per-electrode-unit-group basis, which reduces the number of test data acquisitions and improves testing efficiency compared to existing electrode units. At the same time, the temperature of the electrode unit group is basically the same.The AC line 3254 on the first latitudinal connection portion 3222A is directly in contact with the dielectric layer 347, which is equivalent to increasing the contact area between the conductive sheet 342 and the dielectric layer 347 of the electrode unit group, thereby increasing the capacitance of the entire electrode unit group. Since the contact area between the conductive sheet 342, AC line 3254 and dielectric layer 347 of the ten electrode unit groups of the electrode array 32 is equal, the capacitance of each electrode unit group is equal, making the heating of the ten electrode unit groups tend to be consistent. Therefore, when performing tumor treatment for a long time through the electrode patch 30, it is easier to uniformly adjust the AC signal applied to the electrode patch 30 based on the temperature detected by the temperature sensor 321, avoiding low-temperature burns to the patient's body surface caused by inconsistent heating of each electrode unit 320 or severe heating of a certain electrode unit 320.

[0074] Referring to FIG10, an alloy layer 348 is further laid on the dielectric layer 347. Alloy layer 348 covers only the dielectric layer 347, and adhesive component 33 is attached to alloy layer 348. Alloy layer 348 serves as an auxiliary layer to increase the conductivity between dielectric layer 347 and adhesive component 33. The size of alloy layer 348 is slightly smaller than that of dielectric layer 347. Alloy layer 348 covers the inner wall of heat dissipation hole 340, which can improve the heat dissipation performance of electrode unit 320. Alloy layer 348 can be made of one or more of zinc-aluminum alloy, zinc-copper alloy, silver-titanium, or graphite. Alloy layer 348 can be deposited on the surface of dielectric layer 347 using vapor deposition. The thickness of alloy layer 348 is 3-10 nm. Alloy layer 348 is optional and not required. Electrode array 32 also includes a cover film 349 integrally deposited on the back side of substrate 325. As shown in Figure 6, the eight temperature sensing lines 3253 disposed on the back of the substrate 325 are all laid on the back of the substrate 325 through a cover film 349. These temperature sensing lines 3253 penetrate the substrate 325 and are electrically connected to the corresponding signal pads 345 on the front of the main body 3250 of the substrate 325. The front of the wiring portion 323 is covered by an insulating layer 346, and the back of the wiring portion 323 is covered by a cover film 349. The insulating layer 346 and the cover film 349 are provided with corresponding windows (not labeled) at the locations of each gold finger 3231 of the wiring portion 323 to expose each gold finger 3231, so that the gold fingers 3231 can be soldered to the corresponding lines in the wires (not shown).

[0075] Figure 10 is a cross-sectional schematic diagram of an electrode unit 320 without a temperature sensor 321. The electrode unit 320 includes a main body 3250, a conductive sheet 342 disposed on the front side of the main body 3250, a first insulating layer 3461 covering the conductive sheet 342 and the main body 3250, a second insulating layer 3462 and an insulating strip 3463, and an insulating strip covering the first insulating layer 3461, the second insulating layer 3462 and the insulating strip 3463.The first insulating layer 3461 includes the edge band 3463, a portion of the dielectric layer 347 exposed on the conductive sheet 342 in the cutout area (unlabeled), an alloy layer 348 covering the portion of the dielectric layer 347, and a cover film 349 covering the back of the main body 3250. Since the main body 3250 does not have a ground pad 344 and a signal pad 345, the first insulating layer 3461 directly covers the corresponding portions of the main body 3250 and the opening 3421 of the conductive sheet 342.

[0076] FIG11 is a cross-sectional schematic diagram of an electrode unit 320 provided with a temperature sensor 321. The electrode unit 320 includes a main body 3250, a conductive sheet 342 disposed on the front side of the main body 3250, a grounding pad 344 and a signal pad 345 disposed on the front side of the main body 3250 and located in the opening 3421 of the conductive sheet 342, a first insulating layer 3461 covering the conductive sheet 342 and corresponding parts of the main body 3250, a second insulating layer 3462 and an insulating tape 3463, a temperature sensor 321 electrically connected to the grounding pad 344 and the signal pad 345 and sealed by a sealant 343, a dielectric layer 347 covering the first insulating layer 3461, the second insulating layer 3462, the insulating tape 3463 and the sealant 343, and an alloy layer 348 covering the dielectric layer 347 located on the main body 3250. The components include the upper part of the main body 3250, the grounding wire 3252 on the front side of the main body 3250, the temperature measuring wire 3253 on the back side of the main body 3250 (not shown in Figure 11 due to its cross-sectional position, please refer to Figures 5 and 7), the cover film 349 on the back side of the main body 3250 covering the temperature measuring wire 3253, and the reinforcing plate 326 below the cover film 349 corresponding to the temperature sensor 321. Note that the first insulating layer 3461 covers the front side of the main body 3250 within the opening 3421 of the conductive sheet 342, but exposes the grounding pad 344 and the signal pad 345 for soldering the temperature sensor 321. The first insulating layer 3461 between the grounding pad 344 and the signal pad 345 prevents short circuits between them. Part of the conductive sheet 342 also exposes the corresponding part of the insulating layer 346 on the main body 3250 through the hollow area (not labeled) so that the conductive sheet 342 can make contact with the dielectric layer 347 to conduct electricity. The sealant 343 is applied after the insulating layer 346 is laid.

[0077] Figure 12 shows a cross-sectional view of the first latitudinal connection 3222A located between the two electrode units C9 and C10. The first latitudinal connection 3222A includes a connecting strip 3251, two AC lines 3254 arranged at intervals on the front side of the connecting strip 3251, an inner insulating strip 3464 and an outer insulating strip 3465 covering the connecting strip 3251 in such a way that the AC lines 3254 are exposed, and a dielectric layer 347 covering the connection strip 3251.The portion covering the inner insulating strip 3464, the outer insulating strip 3465, and the AC line 3254, the portion of the alloy layer 348 covering the dielectric layer 347 on the connecting strip 3251, and the portion of the cover film 349 located on the back of the connecting strip 3251, the AC line 3254 and the corresponding portion of the dielectric layer 347 are in contact and conductive.

[0078] FIG13 shows a cross-sectional view of a radial connection portion 3221, which includes a connecting strip 3251, a grounding wire 3252 located on the front of the connecting strip 3251, and two AC lines 3254 located on both sides of the grounding wire 3252 and spaced apart, the inner insulating strip 3464 and the outer insulating strip 3465 covering the connecting strip 3251, the grounding wire 3252 and the two AC lines 3254, the temperature measuring wire 3253 located on the back of the connecting strip 3251, and the portion of the cover film 349 covering the back of the connecting strip 3251 and the temperature measuring wire 3253.

[0079] Referring to Figure 9, the dashed lines in Figure 9 show a schematic diagram of the grounding wire 3252 and AC wire 3254 partially covered by the insulating layer 346. The front of the partial connection portion 322 is simultaneously provided with the grounding wire 3252 and two AC wires 3254. The two AC wires 3254 are spaced apart, and a first wiring groove 3256 is formed between them to avoid interference between the AC wire 3254 and the grounding wire 3252. Referring to Figure 13, a temperature measuring wire 3253 is also provided on the back of the connection portion 322 where the grounding wire 3252 is located. The temperature measuring wire 3253 is located directly below the first wiring groove 3256 and coincides with the projection plane of the grounding wire 3252 on the horizontal plane, while avoiding the projection plane of the AC wire 3254 on the horizontal plane as much as possible. In this embodiment, the temperature sensing line 3253 is entirely located within the projection area of ​​the first wiring groove 3256, and its layout avoids the projection of the AC line 3254, thus preventing the electric field formed by the AC line 3254 from coupling to the temperature sensing line 3253 that transmits DC signals. Since the AC line 3254 and the temperature sensing line 3253 would couple the AC electric field used for tumor treatment to the temperature sensing line 3253 that transmits DC signals when they overlap in the horizontal plane, excessive coupling energy would require a stronger buffer circuit on the adapter 20, making the circuit design of the adapter 20 more complex, increasing the circuit board size of the adapter 20, and increasing costs. Therefore, when wiring on the substrate 325 of the electrode array 32, it is necessary to minimize the overlap rate of the projected areas of the AC line 3254 and the temperature sensing line 3253 in the horizontal plane. In this embodiment, the overlap rate of the projected areas of the AC line 3254 and the temperature sensing line 3253 in the horizontal plane is less than 10%. This problem does not exist if the projected areas of the grounding wire 3252 and the temperature measuring wire 3253 on the horizontal plane overlap. This overlap enhances anti-interference capabilities and reduces interference to the AC signal transmitted through the AC line 3254.

[0080] The front of the main body 3250 of the temperature sensor 321 is provided with a conductive sheet 342 and a grounding wire 3252. The conductive sheet 342 has a second wiring groove (unlabeled) to avoid interference between the grounding wire 3252 and the temperature measuring wire 3253 on the back of the main body 3250. The temperature measuring wire 3253 is located directly below the second wiring groove (unlabeled) and within the projected area of ​​the second wiring groove (unlabeled) to avoid mutual interference between the signals transmitted through the temperature measuring wire 3253 and the conductive sheet 342. The corresponding insulating tape 3463 is laid on the second wiring groove (unlabeled) to press the corresponding grounding wire 3252 onto the front of the main body 3250. It also provides some support for the arrangement of the temperature measuring wire 3253 on the back of the main body 3250, thereby improving the product yield of the electrode array 32.

[0081] In each peripheral electrode unit group, the electrode unit 320 furthest from the center of the electrode patch 30 is not provided with a temperature sensor 321, and its conductive sheet 342 is not provided with a second wiring groove (unlabeled) for the grounding wire 3252 to pass through. Its conductive sheet 342 is arranged in a circular shape with a central opening.

[0082] This application also provides other embodiments of the electrode array 32. The main difference between the multiple embodiments is the layout of the electrode units 320, the connecting part 322, the wiring part 323 and the conductive traces (unlabeled) of the electrode array 32. These will be described in detail below.

[0083] Second embodiment:

[0084] Referring to FIG14, a plan view of the electrode array 32' of the electrode patch according to the second embodiment of this application is shown. In this embodiment, the electrode array 32' also includes a plurality of spaced-apart electrode units 320', a plurality of temperature sensors 321', a plurality of connecting portions 322' and wiring portions 323'. The temperature sensors 321' are selectively disposed on some of the electrode units 320'. The connecting portions 322' connect two adjacent electrode units 320'. The wiring portions 323' are mounted between two connecting portions 322' and are soldered to or detachably connected to a wire (not shown).

[0085] The electrode array 32 has a total of twenty electrode units 320', which are arranged in a four-row, six-column array. The first and fourth rows each have four electrode units 320', and the second and third rows each have six electrode units 320'. The six electrode units 320' in each of the second and third rows are arranged in a one-to-one correspondence, forming six columns. The four electrode units 320' in each of the first and fourth rows are located in the middle four columns. From left to right, the four electrode units 320' in the first row are defined as electrode units C1', C2', C3', and C4'; the six electrode units 320' in the second row are defined as electrode units C5', C6', C7', C8', C9', and C10'; and the six electrode units 320' in the third row are defined as electrode units C11' and C12'.C13', C14', C15', C16', and the four electrode units 320' in the fourth row are electrode units C17', C18', C19', and C20'.

[0086] The electrode array 32' also includes a number of connecting portions 322' extending along the longitude direction (i.e., column upward) and a latitudinal connecting portion 3222' extending along the latitude direction (i.e., similar to row upward), but in each row, some adjacent two electrode units 320' are connected by a latitudinal connecting portion 3222', and the wiring portion 323' is arranged in a "T" shape between the two longitude connecting portions 32221'.

[0087] Unlike the electrode array 32 shown in FIG2, the electrode units 320' in this embodiment are arranged in a straight line in both the row and column directions. Adjacent electrode units 320' in each of the second to fifth columns are connected by corresponding longitudinal connecting parts 3221'. Adjacent electrode units 320' in the four middle columns of the second row are disconnected in the row direction, that is, there is no corresponding latitudinal connecting part 3222' between adjacent electrode units 320' in the four middle columns of the row; adjacent electrode units 320' in the four middle columns of the third row are also disconnected in the row direction, that is, there is no corresponding latitudinal connecting part 3222' between adjacent electrode units 320' in the four middle columns of the third row. The aforementioned "T"-shaped connector 323' is provided between the radial connection portion 3221' connecting the two electrode units 320' located in the second row and third column and the third row and third column and the radial connection portion 3221' connecting the two electrode units 320' located in the second row and fourth column and the third row and fourth column.

[0088] The composition of the electrode unit group in this embodiment is also different from that in the first embodiment. Specifically, in this embodiment, the electrode unit group consists of a first electrode unit group formed by two electrode units C1' and C2' located in the first row and the latitudinal connection portion 3222' between them; a second electrode unit group formed by two electrode units C3' and C4' located in the first row and the latitudinal connection portion 3222' between them; a third electrode unit group formed by two electrode units C5' and C6' located in the second row and the latitudinal connection portion 3222' between them; a fourth electrode unit group formed by two electrode units C7' and C13' located in the third column and the longitudinal connection portion 3221' between them; a fifth electrode unit group formed by two electrode units C8' and C14' located in the fourth column and the longitudinal connection portion 3221' between them; a sixth electrode unit group formed by two electrode units C9' and C10' located in the second row and the latitudinal connection portion 3222' between them; and a third electrode unit group formed by two electrode units C11' and C12' located in the third row and the latitudinal connection portion 3222' between them.The seventh electrode unit group formed by the connecting portion 3222', the eighth electrode unit group formed by the two electrode units C15' and C16' located in the third row and the latitudinal connecting portion 3222' between them, the ninth electrode unit group formed by the two electrode units C17' and C18' located in the fourth row and the latitudinal connecting portion 3222' between them, and the tenth electrode unit group formed by the two electrode units C19' and C20' located in the fourth row and the latitudinal connecting portion 3222' between them.

[0089] Among the ten electrode unit groups of the electrode array 32', the fourth electrode unit group and the fifth electrode unit group are located at the center of the electrode array 32' and are defined as the central electrode unit group; the other eight electrode unit groups surround the periphery of the central electrode unit group and are defined as the peripheral electrode unit group. The aforementioned latitudinal connecting portions 3222' include several first latitudinal connecting portions 3222A' connecting two electrode units 320' within each electrode unit group, and several second latitudinal connecting portions 3222B' connecting two adjacent electrode units 320' in two adjacent peripheral electrode unit groups (page 13 / 15 of specification, CN 121102722 A). The two electrode units 320' within each electrode unit group have the same electrical properties and the same heat generation, so their temperatures are also basically the same. The specific reasons have been explained in detail in the first embodiment and will not be repeated here.

[0090] Referring to Figures 14 to 17, the layer structure of the electrode array 32' in this embodiment is the same as that of the electrode array 32 in the first embodiment. It also includes a substrate 325' having several main body portions 3250' and several connecting strips 3251'. The electrode unit 320' also has a conductive sheet 342' with a through hole (not shown) at the center on the main body portion 3250'. Some of the electrode units 320' have grounding pads 344' and signal pads 345' for electrical connection with temperature sensor 321' in the opening (not shown) of the conductive sheet 342'. The electrode array 32' has several conductive traces (not labeled) arranged on the substrate 325'. The conductive traces (not labeled) include grounding wires 3252' for transmitting grounding signals, eight temperature measuring wires 3253' for transmitting DC signals, and several AC lines 3254' for transmitting AC signals. The aforementioned wiring section 323' is provided with eleven gold fingers 3231', one of which is connected to the grounding wire 3252'; one of which is connected to the AC line 3254'; one of which is connected to the shielding layer (not shown) of the conductor (not shown) and grounded for electromagnetic shielding and to prevent signal interference; the remaining eight gold fingers 3231' are respectively connected to the temperature measuring wire 3253'.

[0091] The electrode array 32' of this embodiment also includes partially covering the main body 3250' and the connecting section 322', and completely coveringThe electrode array 32' is provided on the substrate 325' in the form of a wiring portion 323'. An insulating layer 346' is disposed on the insulating layer 346' in units of electrode unit groups, and a dielectric layer (not shown) is disposed on the conductive sheet 342' (not covered by the insulating layer 346') and the corresponding AC line 3254' located within the electrode unit groups. An alloy layer 348' is disposed on the dielectric layer (not shown) in units of electrode unit groups, and a cover film (not shown) is disposed entirely on the back side of the substrate 325'. For the specific layer structure of the electrode array 32' in this embodiment, please refer to the relevant description of the electrode array 32 in the first embodiment, which will not be repeated here.

[0092] Referring to Figures 16 and 17, the arrangement of the conductive traces (unlabeled) of the electrode array 32' on the substrate 325' in this embodiment differs from the arrangement of the conductive traces (unlabeled) of the electrode array 32 on the substrate 325 in the first embodiment in that: the grounding wire 3252' is mainly distributed on the front side of the substrate 325'. The grounding wire 3252' is led out from a gold finger 3231' on the wiring part 323' and then divided into multiple branches. After extending along the corresponding longitudinal connection part 3221' and latitudinal connection part 3222', it is arranged on the substrate 325' in an electrically connected manner with each grounding pad 344' located at the center of the eight electrode units C2', C3', C6', C9', C12', C15', C18', C19'.

[0093] Specifically, the grounding wire 3252' adopts a double-sided wiring design. After being led out from the corresponding gold finger 3231' on the front of the connector 323', it passes through the corresponding connecting strip 3251' to its back side. After avoiding the AC line 3254' located on the connector 323' of the electrode array 32', it passes through the corresponding connecting strip 3251' to its front side again, and then splits into left and right branches respectively.

[0094] The left branch extends to the left to reach the meridional connector 3221' located in the fourth electrode unit group, passes through the connecting strip 3251' of the meridional connector 3221' to its back side, and avoids the AC line 3254' located on the meridional connector 3221'. Then, the connecting strip 3251' passes through the radial connection portion 3221' again to its front side, and then splits into two branches, one on the upper left and one on the lower left, respectively, along the radial connection portion 3221'. The upper left branch extends upward along the column direction of the third column of electrode units 320', passes through the center of the electrode unit C7' located in the second row and third column, and connects with the grounding pad 344' of the electrode unit C2' located in the first row and third column. Then, it extends to the left along the row direction of the first row of electrode units 320', passes through the center of the electrode unit C1' located in the first row and second column, and then extends downward along the column direction of the second column of electrode units 320' to the center of the electrode unit C6' located in the second row and second column, and connects with the grounding pad 344' of the electrode unit C6'. The lower left branch extends along the third column of electrode units...Unit 320' extends downward in the column direction, and after passing the center of electrode unit C13' located in the third row and third column, it connects with the ground pad 344' of electrode unit C18' located in the third row and third column. Then, it extends to the left along the row direction of electrode unit 320', and after passing the center of electrode unit C17' located in the second column of the fourth row, it extends upward along the column direction of electrode unit 320' to the center of electrode unit C12' located in the second column of the third row, and connects with the ground pad 344' of electrode unit C12'.

[0095] The right branch extends to the right to reach the meridional connection 3221' located in the fifth electrode unit group, and then passes through the connecting strip 3251' of the meridional connection 3221' to its back side, and avoids the AC line 3254' located on the meridional connection 3221'. Then, the connecting strip 3251' passes through the radial connection portion 3221' again to its front side, and then splits into two branches, one to the upper right and one to the lower right, respectively, along the radial connection portion 3221'. The upper right branch extends upward along the column direction of the fourth column electrode unit 320', passes through the center of the electrode unit C8' located in the fourth column of the second row, and connects with the grounding pad 344' of the electrode unit C3' located in the fourth column of the first row. Then, it extends to the right along the row direction of the first row electrode unit 320', passes through the center of the electrode unit C4' located in the fifth column of the first row, and then extends along the fifth column electrode unit... The 320' column extends downward to the center of electrode unit C9' located in the second row and fifth column and is connected to the ground pad 344' of electrode unit C9'; the lower right branch extends downward along the column direction of the fourth column electrode unit 320', passes the center of electrode unit C14' located in the third row and fourth column and is connected to the ground pad 344' of electrode unit C19' located in the fourth row and fifth column, then extends to the right along the row direction of the fourth row electrode unit 320', passes the center of electrode unit 320' located in the fourth row and fifth column, and then extends upward along the column direction of the fifth column electrode unit 320' to the center of electrode unit C15' located in the third row and fifth column and is connected to the ground pad 344' of electrode unit C15'. Figure 17 shows a schematic diagram of the wiring of the temperature sensing wires 3253' on the substrate 325'. The eight temperature sensing wires 3253' are distributed on the reverse side of the substrate 325'. The eight temperature sensing wires 3253' are independent of each other and are led out from a corresponding gold finger 3231' on the wiring part 323'. Each temperature sensing wire 3253' extends from the wiring part 323' and passes through the corresponding electrode unit 320' and the corresponding connection part 322' in the column-row-column direction to the eight electrode units where the temperature sensors 321' are installed.The electrode array 320', which corresponds to one of the electrode units 320' in C2', C6', C18', C12', C3', C9', C19', and C15', passes through the corresponding conductive via (not shown) of the corresponding main body 3250' and is electrically connected to the corresponding signal pad 345' on the front side of the main body 3250'. The overall distribution of the temperature measuring line 3253' is basically similar to that of the grounding line 3252'.

[0096] Referring again to Figures 14 and 15, the electrode array 32' in this embodiment does not have the third latitudinal connection portion 3222C connecting the peripheral electrode unit group and the central electrode unit group as in the electrode array 32 in the first embodiment. In this embodiment, the insulating layer 346' of the electrode array 32' partially covers the main body 3250', the conductive sheet 342', the first latitudinal connecting portion 3222A', and the connecting strip 3251' of the corresponding longitudinal connecting portions 3221' in the fourth and fifth electrode unit groups. It also completely covers the AC line 3254' and grounding line 3252' on the connecting strip 3251' of the second latitudinal connecting portion 3222B', the remaining longitudinal connecting portions 3221', and the connecting portion 323'. The insulating layer 346' on the first latitudinal connecting portion 3222A' and the longitudinal connecting portion 3221' in each electrode unit group exposes the corresponding AC line 3254', allowing the AC line 3254' to directly contact and conduct with the dielectric layer (not shown) laid on it.

[0097] It should be noted that for other related descriptions of the electrode array 32' in the second embodiment, please refer to the relevant descriptions of the electrode array 32 in the first embodiment, which will not be repeated here.

[0098] The above are merely preferred embodiments of this application and are not intended to limit this application. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the scope of protection of this application. Instruction manual, page 15 / 15, 18 CN 121102722 A, Figure 1, Figure 2; Instruction manual drawing, page 1 / 12, 19 CN 121102722 A, Figure 3; Instruction manual drawing, page 2 / 12, 20 CN 121102722 A, Figure 4; Instruction manual drawing, page 3 / 12, 21 CN 121102722 A, Figure 5; Instruction manual drawing, page 4 / 12, 22 CN 121102722 A, Figure 6; Instruction manual drawing, page 5 / 12, 23 CN 121102722 A, Figure 7; Instruction manual drawing, page 6 / 12, 24 CN 121102722 A, Figure 8; Instruction manual drawing, page 7 / 12, 25 CN121102722 A FIGS. 9 and 10, Sheet 8 / 12 of the drawings of the specification, 26 CN 121102722 A FIGS. 11 and 12, Sheet 9 / 12 of the drawings of the specification, 27 CN 121102722 A FIGS. 13 and 14, Sheet 10 / 12 of the drawings of the specification, 28 CN 121102722 A FIG. 15, Sheet 11 / 12 of the drawings of the specification, 29 CN 121102722 A FIGS. 16 and 17, Sheet 12 / 12 of the drawings of the specification, 30 CN 121102722 A {JSHL-26029-HKSPT / 02514747v1} Abstract The invention provides a tumor electric field therapy system and electrode patch thereof. The electrode patch is provided with an electrode array, and the electrode array comprises a plurality of electrode units arranged at intervals and a plurality of connecting parts located between the electrode units and connecting two adjacent electrode units. The electrode units are arranged in at least three rows and three columns, the adjacent electrode units in each row of at least two rows are connected through one connecting part, and the adjacent electrode units in each two column of at least two columns are connected through one connecting part; two adjacent electrode units in each column of at least two columns are arranged in adisconnected mode, and the electrode units arranged in the disconnected mode are all located on a periphery of the electrode array, so that the relative positions of the two adjacent electrode units arranged in the disconnected mode can be freely adjusted in the column direction. At least some of the peripheral electrode units in the electrode patch of the tumor electric field therapy system of the present invention are arranged in the disconnected mode in the column direction, so that the relative positions of the peripheral electrode units in the column direction can be freely adjusted when the electrode patch is pasted, and the electrode patch is prevented from generating wrinkles.

Claims

1. An electrode patch having an electrode array for applying an alternating current signal, the electrode array comprising a plurality of electrode units arranged at intervals and a plurality of connecting portions located between the electrode units and connecting adjacent electrode units, characterized in that, The electrode units are arranged in at least three rows and three columns. In at least two rows, two adjacent electrode units are connected by a connecting part. In at least two columns, two adjacent electrode units are connected by a connecting part. In at least two columns, two adjacent electrode units are disconnected from each other. The disconnected electrode units are located on the periphery of the electrode array so that the relative positions of the disconnected adjacent electrode units in the column direction can be freely adjusted.

2. The electrode patch according to claim 1, characterized in that: The electrode units are distributed in a region of four rows and six columns, and the electrode units arranged in a column-disconnected manner are located in the first column and the sixth column, respectively.

3. The electrode patch according to claim 2, characterized in that: The electrode units arranged in a column-disconnected manner are located in the second and fifth columns respectively. Each column is connected to two adjacent electrode units through a connecting part. The electrode units are located in the third and fourth columns respectively. Each row is connected to two adjacent electrode units through a connecting part.

4. The electrode patch according to claim 2, characterized in that: In the middle four columns, each pair of adjacent electrode units is connected by a connecting part, and in each row, each electrode unit connected by a connecting part is located in the first row and the fourth row respectively.

5. The electrode patch according to claim 4, characterized in that: The two adjacent electrode units located in the middle four columns and in the second row are arranged in a disconnected manner in the row direction.

6. The electrode patch according to claim 5, characterized in that: The two adjacent electrode units located in the middle four columns and the third row are arranged in a disconnected manner in the row direction.

7. The electrode patch according to any one of claims 3 to 6, characterized in that: The electrode array includes 20 electrode units, which are arranged in a manner where there are 4 electrode units in each of the first and fourth rows and they are aligned in the column direction, and 6 electrode units in each of the second and third rows and they are aligned in the column direction; the 4 electrode units in each of the first and fourth rows are located in the middle four columns.

8. The electrode patch according to claim 1, characterized in that: The electrode units are divided into several electrode unit groups according to their pairwise groups. The several electrode unit groups are further divided into peripheral electrode unit groups located around the electrode array and central electrode unit groups surrounded by the peripheral electrode unit groups, with the central electrode unit group located in the middle of the electrode array.

9. The electrode patch according to claim 8, characterized in that: Each of the electrode unit groups includes two adjacent electrode units and a connection portion connecting the two adjacent electrode units, and the electrode array has a dielectric layer laid out with respect to the electrode unit groups.

10. The electrode patch according to claim 9, characterized in that: The dielectric layer is disposed in a discontinuous manner between each of the electrode unit groups.

11. The electrode patch according to claim 9, characterized in that: The electrode array further includes an alloy layer laid on the electrode unit group, the alloy layer being disposed on the corresponding dielectric layer.

12. The electrode patch according to claim 9, characterized in that: Each electrode unit in each electrode unit group includes a main body, a conductive sheet disposed on the main body, and an insulating layer disposed on the main body that allows the conductive sheet to be exposed. The portion of the conductive sheet exposed in the insulating layer is in direct contact with the dielectric layer and is electrically connected.

13. The electrode patch according to claim 12, characterized in that: The connection portion connecting two adjacent electrode units within each electrode unit group includes a connecting strip connected to the corresponding main body, an AC line spaced apart on the connecting strip, and an insulating strip on the connecting strip that allows the AC line to be exposed. The AC line is in direct contact with the dielectric layer and electrically connects the conductive sheets of two adjacent electrode units in each electrode unit group located on their respective main bodies.

14. The electrode patch according to claim 12, characterized in that: The connecting portion connecting two adjacent electrode units in two adjacent electrode unit groups includes a connecting strip connected to the corresponding main body, AC lines spaced apart on the connecting strip, a grounding wire on the connecting strip and located between the spaced AC lines, and an insulating layer on the connecting strip covering the AC lines and the grounding wire.

15. The electrode patch according to claim 12, characterized in that: The connecting portion connecting two adjacent electrode units in two adjacent electrode unit groups includes a connecting strip connected to the corresponding main body, an AC line spaced on the connecting strip, and an insulating strip on the connecting strip that covers the AC line.

16. The electrode patch according to any one of claims 9 to 15, characterized in that: The dielectric layer is made of a polymer and has a dielectric constant of not less than 20.

17. The electrode patch according to claim 8, characterized in that: The electrode array also includes several temperature sensors respectively disposed on a corresponding electrode unit of the corresponding peripheral electrode unit group.

18. The electrode patch according to claim 17, characterized in that: Each of the temperature sensors is located on an electrode unit in the corresponding peripheral electrode unit group, near the center of the electrode array.

19. The electrode patch according to claim 8, characterized in that: At least some of the adjacent peripheral electrode unit groups have variable spacing in the column direction.

20. A tumor electric field therapy system, characterized in that: Includes the electrode patch as described in any one of claims 1-19.

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