Automated synthesis platform and control method thereof

Abstract

This invention discloses an automated synthesis platform and its control method. The automated synthesis platform includes a base, a reactant addition module, a dispensing module, a reaction module, a characterization module, a storage module, and a mechanical transport arm. The base is equipped with reactant addition stations, sample dispensing stations, reaction stations, characterization stations, and storage stations. The reactant addition module includes a support structure and a pipetting addition structure. The support structure supports the raw material bottles and reaction bottles, while the pipetting addition structure is located above the support structure for aspirating and adding raw materials. The dispensing module adds raw materials to the raw material bottles. The reaction module stirs and heats the reactants in the reaction bottles. The characterization module measures the products. The storage module is located at the storage station to store raw material bottles or reaction bottles. The mechanical transport arm is located on the base and between multiple stations to transport reaction bottles. This configuration improves synthesis throughput and parallel processing capabilities while also providing high scalability.

Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202610659049.0 (22) Application Date 2026.05.13 (71) Applicant Hong Kong Quantum Artificial Intelligence Laboratory Limited Address Room 909-10, 912-13, 915, 1305, 17W Building, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong, China (72) Inventors Ye Junxian, Zhao Ying, Zhu Jianfeng, Liu Jie, Cui Haozhe, Chen Guanhua (74) Patent Agency Shenzhen Century Hengcheng Intellectual Property Agency 44287 Patent Attorney Zhan Shicheng (51) Int.Cl. B01J 19 / 18 (2006.01) B01J 4 / 00 (2006.01) B01J 19 / 00 (2006.01) (54) Invention Title: Automated Synthesis Platform and Control Method Thereof (57) Abstract: This invention discloses an automated synthesis platform and its control method. The automated synthesis platform includes a base, a reactant addition module, a dispensing module, a reaction module, a characterization module, a storage module, and a mechanical transfer arm. The base is equipped with reactant addition stations, sample dispensing stations, reaction stations, characterization stations, and storage stations. The reactant addition module includes a support structure and a pipetting addition structure. The support structure supports the raw material bottle and the reaction bottle. The pipetting addition structure is located above the support structure and is used to absorb and add raw materials. The dispensing module is used to add raw materials into the raw material bottle. The reaction module is used to stir and heat the reactants in the reaction bottle. The characterization module is used to measure the product. The storage module is set at the storage station and is used to store the raw material bottle or the reaction bottle. The mechanical transfer arm is located on the base and between multiple stations to transfer the reaction bottle. This configuration improves the synthesis throughput and parallel processing capability, and also has high scalability. Claims (3 pages), Description (13 pages), Drawings (5 pages), CN 122558404 A, 2026.08.14, CN 1 22 55 84 04 A. 1. An automated synthesis platform, characterized in that it comprises: a base, the base having spaced-apart reactant addition stations, sample dispensing stations, reaction stations, characterization stations, and storage stations; a reactant addition module, including a support structure and a pipetting addition structure, the support structure being disposed on the base corresponding to the reactant addition stations and used to support multiple raw material bottles and multiple reaction bottles, the pipetting addition structure being spaced above the support structure and movable in at least a first horizontal direction and a second horizontal direction, the pipetting addition structure being used to add raw materials from the multiple raw material bottles to the reaction bottles according to an experimental formulation; and a dispensing module, disposed on the base corresponding to the sample dispensing station, the dispensing module being connected to multiple raw material tanks for dispensing raw materials into the multiple raw material bottles;A reaction module, located on the base corresponding to the reaction station, is used to carry the reaction flask for stirring and heating the reactants in the reaction flask; a characterization module, located on the base corresponding to the characterization station, is used to sequentially hold multiple reaction flasks and measure the products in the reaction flasks; a storage module, located on the base corresponding to the storage station, has multiple storage positions, each of which is used to store one of the raw material bottles or one of the reaction flasks; and a mechanical transfer arm, located on the base and between the multiple stations, the mechanical transfer arm being at least partially movable to the multiple stations to transfer the reaction flasks between the multiple stations. 2. The automated synthesis platform as claimed in claim 1, wherein the pipetting and adding structure comprises: a displacement platform, including a base, a first movable part, and a second movable part, the base being disposed on the base and avoiding the supporting structure, the first movable part being movably disposed on the base along a first horizontal direction and located above the supporting structure, and the second movable part being movably disposed on the first movable part along a second horizontal direction; and a pipette, disposed on the second movable part to move synchronously with the second movable part, the pipette being used to aspirate the raw material in the raw material bottle and add the raw material to the reaction flask. 3. The automated synthesis platform as claimed in claim 2, wherein the reactant adding module further comprises a pipette tip replacement rack, the pipette tip replacement rack being spaced apart from the supporting structure and used to carry multiple pipette tips; the pipette comprising a body and a locking part, the body being disposed on the second movable part, the locking part being disposed on the body, and having a locked state for locking the pipette tip to the body, and an unlocked state for unlocking the pipette tip. 4. The automated synthesis platform as claimed in claim 3, wherein the reactant addition module further includes a waste basket, the waste basket being disposed between the pipette tip replacement rack and the supporting structure, and located below the pipette, the upper end of the waste basket being open to receive the pipette tip removed from the pipette. 5. The automated synthesis platform as claimed in claim 1, wherein the reaction module includes: a reaction seat having a plurality of spaced-apart reaction positions for supporting reaction flasks; and a plurality of reaction processing units, each of the reaction processing units corresponding to a plurality of reaction positions disposed on the reaction seat, and each reaction processing unit being independently operable, each reaction processing unit including a stirring element and a heating element, the stirring element being used to stir the reactants in the reaction flask, and the heating element being used to regulate the temperature of the reaction system in the reaction flask. 6. The automated synthesis platform as claimed in claim 1, wherein the base further includes a sealing station; Claims 1 / 3 pages 2 CN122558404 A The automated synthesis platform further includes a sealing module disposed on the base corresponding to the sealing station. The sealing module includes: a fixing structure disposed on the base, the fixing structure being used to fix the reaction flask and restrict the rotation of the reaction flask along an axis extending vertically; and a cap feeding structure disposed at intervals from the fixing structure, including a receiving part and a pushing part. The receiving part is disposed on the base and forms a receiving cavity, the receiving cavity being used to hold the cap. One end of the receiving part is connected to the receiving cavity to form a feeding position. The pushing part is disposed in the receiving cavity and is disposed away from the feeding position. At least part of the pushing part is movable in the direction toward the feeding position to push the cap to the feeding position. 7. The automated synthesis platform as claimed in claim 6, wherein the fixed structure comprises a plurality of movable blocks, all of which are disposed on the base and are at least partially movably arranged toward or away from each other, the plurality of movable blocks are used to jointly clamp the reaction flask, and each movable block is further provided with a flexible abutment portion for contacting the reaction flask. 8. The automated synthesis platform as claimed in claim 1, wherein the automated synthesis platform further comprises a control device, the control device being electrically connected to the reactant addition module, the dispensing module, the reaction module, the characterization module, and the mechanical transfer arm, the control device comprising a memory, a processor, and a control program for the automated synthesis platform stored in the memory and executable on the processor, the control program for the automated synthesis platform being configured to implement the steps of a control method for the automated synthesis platform. 9. A control method for an automated synthesis platform, characterized in that, based on the automated synthesis platform as described in any one of claims 1 to 8, the control method for the automated synthesis platform includes: controlling a dispensing module to dispense different raw materials into multiple raw material bottles; controlling a reactant adding module to add the raw materials from the multiple raw material bottles to a reaction flask according to multiple preset experimental formulas; controlling a mechanical transfer arm to transfer the reaction flask to a reaction module, while simultaneously controlling the reaction module to regulate the reaction process within the reaction flask under preset reaction conditions; controlling the mechanical transfer arm to transfer the reaction flask to a characterization module, while simultaneously controlling the characterization module to measure the physicochemical properties of the product within the reaction flask; and controlling the mechanical transfer arm to transfer the reaction flask to a storage position of a storage module. 10. The control method for the automated synthesis platform as described in claim 9, characterized in that, the base further has a sealing station; the automated synthesis platform further includes a sealing module disposed on the base corresponding to the sealing station, the sealing module comprising: a fixing structure disposed on the base, the fixing structure being used to fix the reaction flask and restrict the rotation of the reaction flask along an axis extending vertically; and,A bottle cap feeding structure, spaced apart from the fixed structure, includes a receiving part and a pushing part. The receiving part is located on the base and forms a receiving cavity for holding bottle caps. One end of the receiving part is connected to the receiving cavity to form a feeding position. The pushing part is located in the receiving cavity and is located away from the feeding position. At least part of the pushing part is movable in the direction toward the feeding position to push the bottle cap to the feeding position. Before the step of controlling the mechanical transfer arm to transfer the reaction bottle to the reaction module and controlling the reaction module to regulate the reaction process in the reaction bottle with preset reaction conditions, the structure further includes: controlling the mechanical transfer arm to transfer the reaction bottle to the sealing module; controlling the fixed structure to fix the reaction bottle and controlling the mechanical transfer arm to pick up the bottle cap at the feeding position; controlling the mechanical transfer arm to install the bottle cap onto the mouth of the reaction bottle. Claims 3 / 3 Page 4 CN 122558404 A Automated Synthesis Platform and Control Method Technical Field

[0001] This invention relates to the field of intelligent automation technology, and particularly to an automated synthesis platform and its control method. Background Art

[0002] In recent years, with the rapid development of new energy technologies, the research and development needs of new battery materials (such as solid electrolyte materials, liquid electrolyte materials, positive electrode active materials, etc.) have become increasingly urgent. Traditional material synthesis and characterization processes are highly dependent on manual operation, covering multiple links such as accurate weighing and sequential addition of reactants, precise control of the reaction environment (such as temperature, atmosphere, pressure), reaction process monitoring, product post-processing, material characterization (such as XRD, SEM, electrochemical testing), and data acquisition and analysis.

[0003] These steps are not only time-consuming and labor-intensive, but also suffer from poor experimental repeatability and batch-to-batch consistency due to individual differences in operators, which seriously restricts the efficiency and quality of material research and development.

[0004] Therefore, to address the above challenges, laboratory automation and intelligence have become an important development trend in the field of materials science. However, existing automated platforms have insufficient synthesis throughput and limited parallel synthesis capabilities. Most are customized for specific types of chemical reactions or specific material systems, and their hardware architecture and software control logic are highly coupled with the target reaction, making it impossible to simultaneously accommodate multiple synthesis schemes. Summary of the Invention

[0005] The main objective of this invention is to propose an automated synthesis platform and its control method, aiming to improve the problems of insufficient synthesis throughput, limited parallel synthesis capabilities, and inability to simultaneously accommodate multiple synthesis schemes in existing automated platforms.

[0006] To achieve the above objective, the automated synthesis platform proposed in this invention includes: a base, wherein the base has reactant addition stations, sample dispensing stations, reaction stations, characterization stations, and storage stations arranged at intervals;A reactant addition module includes a support structure and a pipetting addition structure. The support structure is located on the base corresponding to the reactant addition station and supports multiple raw material bottles and multiple reaction bottles. The pipetting addition structure is spaced above the support structure and is movable at least in a first horizontal direction and a second horizontal direction. The pipetting addition structure is used to add raw materials from the multiple raw material bottles to the reaction bottles according to the experimental formula. A dispensing module is located on the base corresponding to the sample dispensing station. The dispensing module is connected to multiple raw material tanks to dispense raw materials into the multiple raw material bottles. A reaction module is located on the base corresponding to the reaction station. The reaction module supports the reaction bottles and is used to stir and heat the reactants in the reaction bottles. A characterization module is located on the base corresponding to the characterization station. The characterization module is used to sequentially hold multiple reaction bottles and measure the products in the reaction bottles. A storage module, corresponding to the storage station, is disposed on the base. The storage module has multiple storage positions, each of which is used to store one of the raw material bottles or one of the reaction bottles; and a mechanical transfer arm, disposed on the base and located between the multiple stations. The mechanical transfer arm is at least partially movable to the multiple stations to transfer the reaction bottles between the multiple stations. Specification 1 / 13 pages 5 CN 122558404 A

[0007] In one embodiment, the pipetting and adding structure includes: a displacement platform, including a base, a first movable part, and a second movable part. The base is disposed on the base and is arranged to avoid the support structure. The first movable part is movably disposed on the base along a first horizontal direction and is located above the support structure. The second movable part is movably disposed on the first movable part along a second horizontal direction; and a pipette, disposed on the second movable part to move synchronously with the second movable part. The pipette is used to draw raw materials from the raw material bottle and add the raw materials to the reaction bottle.

[0008] In one embodiment, the reactant addition module further includes a pipette tip replacement rack, which is spaced apart from the support structure and is used to carry multiple pipette tips; the pipette includes a main body and a locking part, the main body is disposed on the second movable part, the locking part is disposed on the main body, and has a locked state for locking the pipette tip to the main body, and an unlocked state for unlocking the pipette tip.

[0009] In one embodiment, the reactant addition module further includes a waste bin, which is spaced apart from the pipette tip replacement rack and the support structure, and is located below the pipette; the upper end of the waste bin is open to receive the pipette tip removed from the pipette.

[0010] In one embodiment, the reaction module includes: a reaction seat, which has multiple spaced reaction positions for carrying reaction bottles;In addition, there are multiple reaction processing units, each of which is located on the reaction seat and corresponds to a plurality of reaction positions. Each reaction processing unit is configured to operate independently. Each reaction processing unit includes a stirring element and a heating element. The stirring element is used to stir the reactants in the reaction flask, and the heating element is used to regulate the temperature of the reaction system in the reaction flask.

[0011] In one embodiment, the base also has a sealing station; the automated synthesis platform further includes a sealing module disposed on the base corresponding to the sealing station, the sealing module including: a fixing structure disposed on the base, the fixing structure being used to fix the reaction bottle and restrict the reaction bottle from rotating along an axis extending vertically; and a bottle cap feeding structure disposed at intervals from the fixing structure, including a receiving part and a pushing part, the receiving part being disposed on the base and forming a receiving cavity, the receiving cavity being used to hold the bottle cap, one end of the receiving part being connected to the receiving cavity to form a feeding position, the pushing part being disposed in the receiving cavity and disposed away from the feeding position, the pushing part being at least partially movable in the direction toward the feeding position to push the bottle cap to the feeding position.

[0012] In one embodiment, the fixing structure includes a plurality of movable blocks, all of which are disposed on the base and are at least partially movably arranged in a direction toward or away from each other. The plurality of movable blocks are used to jointly clamp the reaction flask, and each movable block is also provided with a flexible abutment portion for contacting the reaction flask.

[0013] In one embodiment, the automated synthesis platform further includes a control device, which is electrically connected to the reactant addition module, the dispensing module, the reaction module, the characterization module, and the mechanical transfer arm. The control device includes a memory, a processor, and a control program for the automated synthesis platform stored in the memory and executable on the processor. The control program for the automated synthesis platform is configured to implement the steps of a control method for the automated synthesis platform.

[0014] The present invention also proposes a control method for an automated synthesis platform. Based on the above-mentioned automated synthesis platform, the control method of the automated synthesis platform described in this specification (page 2 / 13, CN 122558404 A) includes: controlling the dispensing module to add different raw materials into multiple raw material bottles; controlling the reactant adding module to add the raw materials from the multiple raw material bottles to the reaction flask according to multiple preset experimental formulas; controlling the mechanical transfer arm to transfer the reaction flask to the reaction module, while controlling the reaction module to regulate the reaction process in the reaction flask under preset reaction conditions; controlling the mechanical transfer arm to transfer the reaction flask to the characterization module, while controlling the characterization module to measure the physicochemical properties of the products in the reaction flask; and controlling the mechanical transfer arm to transfer the reaction flask to the storage position of the storage module.

[0015] In one embodiment, the base also has a sealing station; the automated synthesis platform further includes a sealing module disposed on the base corresponding to the sealing station, the sealing module including: a fixing structure disposed on the base, the fixing structure being used to fix the reaction bottle and restrict the reaction bottle from rotating along an axis extending vertically; and a bottle cap feeding structure disposed at intervals from the fixing structure, including a receiving part and a pushing part, the receiving part being disposed on the base and forming a receiving cavity, the receiving cavity being used to hold the bottle cap, one end of the receiving part being connected to the receiving cavity to form a feeding position, the pushing part being disposed in the receiving cavity and disposed away from the feeding position, the pushing part being at least partially movable in the direction toward the feeding position to push the bottle cap to the feeding position; before the step of controlling the mechanical transfer arm to transfer the reaction bottle to the reaction module and simultaneously controlling the reaction module to regulate the reaction process in the reaction bottle with preset reaction conditions, the platform further includes: controlling the mechanical transfer arm to transfer the reaction bottle to the sealing module; The control fixing structure fixes the reaction flask, and at the same time controls the mechanical transfer arm to pick up the bottle cap at the loading position; the control mechanical transfer arm installs the bottle cap to the mouth of the reaction flask.

[0016] In the technical solution of the present invention, before the automated synthesis platform starts the raw material synthesis work, multiple raw material bottles are stored in multiple storage positions of the storage module, or directly on the support structure; when the raw material synthesis work starts, firstly, the dispensing module adds the raw materials in multiple raw material tanks to multiple raw material bottles, so that multiple raw material bottles contain multiple different raw materials. At this time, if multiple raw material bottles are stored in multiple storage positions of the storage module, before adding reactants, the mechanical transfer arm will first transfer multiple raw material bottles to the support structure in sequence. When multiple raw material bottles and multiple reaction flasks are stored on the support structure, the pipetting and adding structure moves along the first horizontal direction and the second horizontal direction, so as to add different raw materials in multiple raw material bottles in different amounts and contents according to multiple different experimental formulas. The reactants are added to the reaction flasks, thus creating multiple different reaction systems within the flasks. After the reactants are added, the mechanical transfer arm moves to transfer the multiple reaction flasks from the reactant addition station to the reaction station. At this time, the reaction module can provide the required temperature and stirring conditions for the reaction system in each reaction flask according to different experimental formulations, so as to simultaneously complete the parallel synthesis of multiple different reaction systems and fully improve the synthesis throughput of the platform. After the reaction is completed, the mechanical transfer arm then transfers the multiple reaction flasks from the reaction station to the characterization station and stores them in the characterization module. The characterization module can characterize the products after the chemical reaction in the reaction flasks.The system performs automated characterization tests and data acquisition on the products, and measures the specified physicochemical properties of the products in the reaction flasks according to different experimental formulations. After characterization, the mechanical transfer arm can transfer multiple reaction flasks to the storage module described on page 3 / 13 of the specification (CN 122558404 A), and place them in multiple storage positions for storage, which can be retrieved later when needed. With this configuration, the automated synthesis platform, through its modular layout of multiple independent workstations, can simultaneously support the parallel synthesis and characterization of multiple different reaction systems. Each workstation can operate independently without interference, effectively improving synthesis throughput and parallel processing capabilities, adapting to various different synthesis schemes, and possessing high scalability. It eliminates the need for customized modifications for specific reactions, solving the problem of high coupling between existing platform hardware and target reactions, effectively improving the efficiency of materials research and development, and ensuring the repeatability and consistency of different batches of experiments.

[0017] Brief Description of the Drawings: In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.

[0018] Figure 1 is a structural schematic diagram of an embodiment of the automated synthesis platform provided by the present invention; Figure 2 is a structural schematic diagram of the automated synthesis platform in Figure 1 (another direction); Figure 3 is a flowchart of a first embodiment of the control method of the automated synthesis platform provided by the present invention; Figure 4 is a flowchart of a second embodiment of the control method of the automated synthesis platform provided by the present invention; Figure 5 is a schematic diagram of the device structure of the hardware operating environment involved in the control method of the automated synthesis platform in the embodiments of the present invention.

[0019] Explanation of reference numerals in the accompanying drawings: 100, automated synthesis platform; 1, base; 2, reactant addition module; 21, support structure; 22, pipetting addition structure; 221, base; 222, first movable part; 223, second movable part; 224, pipette; 23, pipette tip replacement rack; 3, dispensing module; 4, reaction module; 41, reaction seat; 42, reaction processing part; 5, characterization module; 6, storage module; 7, mechanical transfer arm; 8, sealing module; 81, fixing structure; 811, movable block; 82, bottle cap feeding structure.

[0020] The realization of the purpose, functional characteristics and advantages of the present invention will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Description of Embodiments

[0021] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.All other embodiments obtained by those skilled in the art without creative effort in accordance with the embodiments of the present invention are within the scope of protection of the present invention.

[0022] It should be noted that if the embodiments of the present invention involve directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative positional relationship and movement of the components in a specific posture. If the specific posture changes, the directional indications will also change accordingly.

[0023] In addition, if the embodiments of the present invention involve descriptions such as "first" and "second", the descriptions such as "first" and "second" are only for descriptive purposes and cannot be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Thus, features defined with "first" and "second" can explicitly or implicitly include at least one of the features. In addition, if "and / or" or "and / or" appears throughout the text, its meaning includes three parallel solutions. Taking "A and / or B" as an example, it includes solution A, solution B, or a solution that satisfies both A and B. In addition, the technical solutions of various embodiments can be combined with each other, but it must be based on the ability of those skilled in the art to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be considered that such combination of technical solutions does not exist and is not within the scope of protection claimed by the present invention.

[0024] The present invention proposes an automated synthesis platform, which aims to improve the problems of insufficient synthesis throughput, limited parallel synthesis capability, and inability to simultaneously accommodate multiple synthesis schemes of existing automated platforms.

[0025] Please refer to Figures 1 and 2. In one embodiment of the present invention, the automated synthesis platform 100 includes a base 1, a reactant addition module 2, a dispensing module 3, a reaction module 4, a characterization module 5, a storage module 6, and a mechanical transfer arm 7. The base 1 has reactant addition stations, sample dispensing stations, reaction stations, characterization stations, and storage stations arranged at intervals. The reactant addition module 2 includes a support structure 21 and a pipetting addition structure 22. The support structure 21 is located on the base 1 corresponding to the reactant addition station and is used to support multiple raw materials. The base 1 contains a sample feeding module 3 and multiple reaction flasks. The sample feeding structure 22 is spaced above the supporting structure 21 and is movable at least in the first and second horizontal directions. The sample feeding structure 22 is used to add raw materials from multiple sample bottles to the reaction flasks according to the experimental formula. The sample feeding module 3 is located on the base 1, corresponding to the sample feeding station. The sample feeding module 3 is connected to multiple raw material tanks to add raw materials to multiple sample bottles. The reaction module 4 is located on the base 1, corresponding to the reaction station. The reaction module 4 is used for...The base 1 is used to support the reaction flasks for stirring and heating the reactants in the reaction flasks. The characterization module 5 is located on the base 1 corresponding to the characterization station. The characterization module 5 is used to sequentially hold multiple reaction flasks and measure the products in the reaction flasks. The storage module 6 is located on the base 1 corresponding to the storage station. The storage module 6 has multiple storage positions, each of which is used to store one of the raw material bottles or one of the reaction flasks. The mechanical transfer arm 7 is located on the base 1 and is situated between the multiple stations. The mechanical transfer arm 7 is at least partially movable to the multiple stations to transfer the reaction flasks between the multiple stations.

[0026] In the technical solution of this invention, before the automated synthesis platform 100 begins raw material synthesis, multiple raw material bottles are stored in multiple storage positions of the storage module 6, or directly on the support structure 21. When the raw material synthesis begins, the dispensing module 3 first adds the raw materials from the multiple raw material tanks to the multiple raw material bottles, so that the multiple raw material bottles contain multiple different raw materials. If the multiple raw material bottles are stored in multiple storage positions of the storage module 6, before adding reactants, the mechanical transfer arm 7 will sequentially transfer the multiple raw material bottles to the support structure 21. When both the multiple raw material bottles and the multiple reaction flasks are stored on the support structure 21, the pipetting and adding structure 22 moves along a first horizontal direction and a second horizontal direction to add different raw materials from the multiple raw material bottles to the reaction flasks in different amounts and concentrations according to multiple different experimental formulations, thereby allowing the multiple reaction flasks to... The automated synthesis platform 100 contains multiple different reaction systems. After the reactants are added, the mechanical transfer arm 7 moves to transfer multiple reaction flasks from the reactant addition station to the reaction station. At this time, the reaction module 4 can provide the required temperature and stirring conditions for the reaction system in each reaction flask according to different experimental formulations, so as to simultaneously complete the parallel synthesis of multiple different reaction systems and fully improve the synthesis throughput of the platform. After the reaction is completed, the mechanical transfer arm 7 transfers multiple reaction flasks from the reaction station to the characterization station and stores them in the characterization module 5. The characterization module 5 can automatically characterize and test the products after the chemical reaction in the reaction flasks and collect data, and perform specified physicochemical property measurements on the products in the reaction flasks according to different experimental formulations. After characterization is completed, the mechanical transfer arm 7 can transfer multiple reaction flasks to the storage station and place them in multiple storage positions for storage, so as to be retrieved later when needed. With this configuration, the automated synthesis platform 100, through the modular layout of multiple independent stations,It can simultaneously support the parallel synthesis and characterization of multiple different reaction systems. Each station can operate independently without interference, which effectively improves the synthesis throughput and parallel processing capability, and can adapt to a variety of different synthesis schemes. It has high scalability and does not require customized modification for the specific reaction specified on page 5 / 13 of the specification (CN 122558404 A). It solves the problem of high coupling between the existing platform hardware and the target reaction, effectively improves the efficiency of material research and development, and ensures the repeatability and consistency of different batches of experiments.

[0027] Furthermore, in this embodiment, each module is an independent functional unit, which can be flexibly configured, replaced, or expanded according to the synthesis requirements of different battery material systems. For example, when facing different types of battery material synthesis requirements, new process requirements can be quickly adapted by replacing or adding the reaction module 4, adjusting the type of characterization instrument in the characterization module 5, etc., without redesigning and building the entire platform, which greatly reduces the development and maintenance costs of the platform.

[0028] It is understood that the present invention is not limited to the specific storage location of the multiple raw material bottles before the start of the raw material synthesis work. The multiple raw material bottles can be stored in the storage module 6 or in the supporting structure 21. In actual setting, the selection can be made according to the needs.

[0029] It should be noted that after the raw material synthesis work is completed, the mechanical transfer arm 7 transfers the multiple reaction bottles to the multiple storage positions of the storage module 6. At this time, each storage position corresponds to one reaction bottle. The storage position and the reaction bottle correspond one-to-one, which facilitates the precise positioning, tracking and management of different products.

[0030] It should be further noted that, in order to further facilitate the intuitive understanding of the one-to-one correspondence between the storage position and the reaction bottle, in a further embodiment of the present invention, the storage position is provided with an identification part, and the reaction bottle is provided with a corresponding part. The identification part and the corresponding part correspond to each other, and the information of the reaction bottle stored in the corresponding storage position can be quickly identified through the identification part, avoiding confusion between different reaction bottles and further ensuring the traceability of experimental data.

[0031] The marking part and the corresponding part can be set in various different forms. In this invention, the marking part and the corresponding part can be set in the form of visual identification such as numbering or identification pattern, or in the form of electronic identification such as electronic position information and reaction bottle information. Of course, other forms can also be set. In actual setting, they can be selected according to the requirements.

[0032] In addition, when the pipetting and adding structure 22 performs the reaction addition work, the pipetting and adding structure 22 first needs to pick up the raw materials in the raw material bottle, and then add the picked-up raw materials to the target reaction bottle according to the experimental formula. In order to ensure that the pipetting and adding structure 22 can perform the picking and adding actions smoothly, in one embodiment of this inventionIn this example, the pipetting and adding structure 22 includes a displacement platform and a pipette 224. The displacement platform includes a base 221, a first movable part 222, and a second movable part 223. The base 221 is disposed on the base 1 and is arranged to avoid the support structure 21. The first movable part 222 is movably disposed on the base 221 along a first horizontal direction and is located above the support structure 21. The second movable part 223 is movably disposed on the first movable part 222 along a second horizontal direction. The pipette 224 is disposed on the second movable part 223 and moves synchronously with the second movable part 223. The pipette 224 is used to aspirate the raw material in the raw material bottle and add the raw material to the reaction bottle. This configuration ensures the stability of the pipette addition structure 22 in picking up and adding liquids. The base 221 provides a base for the pipette 224 to move, and the first movable part 222 and the second movable part 223 allow the pipette 224 to move freely within the horizontal area above the support structure 21, accurately reaching any of the raw material bottles or reaction bottles to complete the aspiration and dispensing operations. This high positioning accuracy and good movement stability ensure the precise addition of different amounts of raw materials, thereby guaranteeing that the proportions of multiple reaction systems meet the experimental formula requirements and improving the reliability of experimental results.

[0033] It should be noted that the present invention does not limit the specific structural form of the first movable part 222 and the second movable part 223. In one embodiment of the present invention, the first movable part 222 can be a first slide rail extending along the second horizontal direction, the second movable part 223 is slidably disposed on the first slide rail, and the base 221 is correspondingly provided with a slide groove extending along the first horizontal direction. The first slide rail is slidably disposed on the slide groove so that the first slide rail as a whole can move along the first horizontal direction, thereby driving the second movable part 223 and the pipette 224 to move along the first horizontal direction. The second movable part 223 slides along the first slide rail to drive the pipette 224 to move along the second horizontal direction. The structure is simple, the movement stability is good, and the processing and manufacturing difficulty is low.

[0034] In another embodiment of the present invention, the first movable part 222 may be configured as a first linear motor module extending in a first horizontal direction, and the second movable part 223 may be configured as a second linear motor module extending in a second horizontal direction. The stator of the first linear motor module is connected to the base 221, and the mover is connected to the stator of the second linear motor module. The mover of the second linear motor module is connected to the pipette 224, thereby achieving high-precision drive in two horizontal directions without the need for additional transmission structures. This results in faster movement response, higher positioning accuracy, and further improvement in the accuracy of pipetting.Accuracy and work efficiency.

[0035] Of course, in other embodiments, the first movable part 222 and the second movable part 223 can also be configured in other structural forms, as long as they can drive the pipette 224 to move in the first horizontal direction and the second horizontal direction. The present invention does not make specific limitations here.

[0036] It is also understood that in the present invention, the specific structural forms of the first movable part 222 and the second movable part 223 can not only be the same, but also different. For example, one of the first movable part 222 and the second movable part 223 can be configured as a slide rail slider structure, and the other can be configured as a linear drive motor module. In actual configuration, it can also be selected according to the requirements.

[0037] However, when using the pipette 224 to aspirate and add raw materials, the pipette 224 will inevitably aspirate various different raw materials. In this case, if the pipette 224 directly aspirates different types of raw materials, it will not only easily lead to cross-contamination between different raw materials, affecting the accuracy of the subsequent reaction system ratio, and thus interfering with the accuracy of the final experimental results, but may also cause different raw materials to react directly in the pipette 224, or even damage the pipette 224 itself, significantly reducing the service life of the equipment. Because, in one embodiment of the present invention, the reactant addition module 2 further includes a pipette tip replacement rack 23, which is spaced apart from the support structure 21 and is used to support multiple pipette tips. The pipette 224 includes a main body and a locking part. The main body is located on the second movable part 223, and the locking part is located on the main body, and has a locking state that locks the pipette tip to the main body, and an unlocking state that unlocks the pipette tip.

[0038] In this embodiment, after the pipette 224 completes one raw material aspiration and addition operation, when the pipette 224 needs to aspirate different types of raw materials, the locking part can switch from the locked state to the unlocked state, unlocking and removing the pipette tip contaminated with the residual liquid of the previous raw material. Then, the first movable part 222 and the second movable part 223 will drive the pipette 224 to move along the first horizontal direction and the second horizontal direction to the pipette tip replacement holder 23, selecting a new clean pipette tip. At this time, the locking part switches from the unlocked state to the locked state again, so that the pipette 224 can lock and fix the new pipette tip to the main body through the locking part, and then the next raw material aspiration and addition operation can be performed. The entire process does not require manual replacement of pipette tips, which avoids cross-contamination between different raw materials, ensures the purity and proportioning accuracy of the reaction system, and also prevents the pipette 224 from being contaminated and corroded by raw materials. This effectively extends the service life of the pipette 224 and also ensures the accuracy of the final experimental results.

[0039] Of course, the present invention does not limit the specific structural form of the locking part. In one embodiment of the present invention, the locking part can lock the main body and the pipetting chamber by means of mechanical locking. For example, the locking part includes an elastic clamp. The elastic clamp contracts and hugs the tail end of the pipetting tip. When the elastic clamp contracts, the pipetting tip can be fixed on the main body. When the elastic clamp opens, the pipetting tip can be released to achieve quick replacement. The structure is simple, the locking is stable, and the operation is highly reliable.

[0040] In another embodiment of the present invention, the locking part can also fix the pipette tip by means of air pressure adsorption. For example, the locking part includes a vacuum generator, which is used to evacuate the inside of the main body to form a negative pressure. The negative pressure is used to adsorb and fix the pipette tip at the lower end of the main body. When it needs to be replaced, air is simply introduced into the inside of the main body to break the negative pressure, and the old pipette tip can be removed. The operation is simpler and the control is more convenient. The corresponding locking structure can be selected according to the actual use needs.

[0041] In another embodiment of the present invention, the locking part can also fix the pipette tip by electromagnetic adsorption. For example, the locking part includes a correspondingly provided magnetic part and a metal part. The magnetic part and the metal part are respectively provided on the main body and the pipette tip. When the magnetic part is energized and generates magnetism, it can adsorb and fix the metal part on the pipette tip. After the power is turned off, the magnetism disappears and the pipette tip can be released. The structure is simple and the response is fast, which can realize a quick replacement operation.

[0042] It is understood that in other embodiments of the present invention, in addition to the above-mentioned structural forms, the locking part can also be set to other structural forms. Those skilled in the art can choose according to actual needs. The present invention does not make specific limitations here.

[0043] It is also understood that the present invention does not limit the specific number of pipettes 224. In the present invention, multiple pipettes 224 can be provided, or only one can be provided. In actual setting, it can be selected according to needs.

[0044] When multiple pipettes 224 are provided, the multiple pipettes 224 can be configured to simultaneously perform the aspiration and addition of raw materials, or the multiple pipettes 224 can be configured to be independently controlled.

[0045] Further, when the locking part switches from the locked state to the unlocked state to remove the old pipette tip, since the pipette 224 is in a suspended state, the old pipette tip will fall directly off the pipette 224. To avoid the old pipette tip falling directly onto the base 1 and contaminating the base 1, or causing the raw materials inside the old pipette tip to splash due to a fall collision, in a further embodiment of the present invention, the reactant is added...Module 2 also includes a waste basket, which is disposed between the pipette tip replacement holder 23 and the support structure 21 and is located below the pipette 224. The upper end of the waste basket is open to receive the pipette tips removed from the pipette 224. With this configuration, before the locking part switches from the locked state to the unlocked state to allow the pipette 224 to remove the old pipette tip, the first movable part 222 and the second movable part 223 actuate to drive the pipette 224 to move along the first horizontal direction and the second horizontal direction to above the waste bin. At this time, the locking part switches from the locked state to the unlocked state again. After the locking part unlocks and removes the old pipette tip, the old tip will fall directly into the open waste bin below for collection. This prevents it from bumping against the base 1 and from causing residual raw materials to splash and contaminate the equipment. This ensures the cleanliness of the operating environment of the automated synthesis platform 100, reduces the frequency of cleaning and maintenance, and further improves the automation level of the platform operation, eliminating the need for manual cleaning of discarded pipette tips in real time.

[0046] Furthermore, since the supporting structure 21 carries multiple reaction flasks, after the liquid addition structure 22 completes the reaction addition work, each of the multiple reaction flasks contains a raw material mixture to be reacted. At this time, in order to improve the working efficiency of the automated synthesis platform 100 and reduce the waiting time, in one embodiment of the present invention, the reaction module 4 includes a reaction seat 41 and multiple reaction processing units 42. The reaction seat 41 has multiple reaction positions arranged at intervals. The reaction positions are used to carry the reaction flasks. The multiple reaction processing units 42 are respectively arranged on the reaction seat 41 corresponding to the multiple reaction positions. Each reaction processing unit 42 is set to work independently. Each reaction processing unit 42 includes a stirring element and a heating element. The stirring element is used to stir the reactants in the reaction flask, and the heating element is used to regulate the temperature of the reaction system in the reaction flask. With this configuration, each reaction position can independently control the temperature and stir the corresponding reaction flask with the cooperation of the corresponding reaction processing unit 42. The reactions do not interfere with each other, ensuring that different reaction systems react under their respective suitable temperature and stirring conditions. It also allows different reaction flasks to complete their reactions independently for different durations, eliminating the need to wait for all reactions to complete before proceeding to the next step. After each reaction flask completes its corresponding pipetting and adding work, the mechanical transfer arm 7 can directly transfer the reaction flask to the corresponding reaction position in the reaction module 4 to begin the reaction. This significantly improves the parallel processing efficiency of the automated synthesis platform 100 and further compresses the overall experimental cycle.

[0047] Furthermore, the present invention does not limit the specific structural form of the reaction processing unit 42. For example, the stirring element can be configured in various forms. In the present invention, the stirring element can be configured as a magnetic stirring element, a mechanical stirring element, or other forms.

[0048] Similarly, the heating element can also be configured in various forms. In the present invention, the heating element can be configured as an infrared heating element, an electric heating wire heating element, or a water bath temperature control element, etc., as long as it can stably regulate the temperature of the reaction system in the corresponding reaction flask. In actual settings, it can be adapted and selected according to the reaction requirements.

[0049] Further, in order to avoid the temperature difference between two adjacent reaction sites from affecting each other's temperature, in a further embodiment of the present invention, the reaction seat 41 is also provided with a plurality of heat insulation parts. Each heat insulation part is provided between two adjacent reaction sites to isolate the heat transfer between two adjacent reaction sites. In this way, the heat of the low-temperature reaction site can be avoided from being affected by the heat of the high-temperature reaction site, and the heat of the high-temperature reaction site can also be avoided from being lost too quickly. This further improves the temperature regulation accuracy of each reaction site on the reaction system, ensures that the reaction can be carried out stably under the preset temperature conditions, and improves the accuracy of the experimental results.

[0050] The present invention does not limit the specific structural form of the multiple reaction sites. In one embodiment of the present invention, the reaction sites can be distributed on the upper end surface of the reaction seat 41 to ensure the supporting ability of the reaction sites for the reaction bottle. In another embodiment of the present invention, the upper end surface of the reaction seat 41 is provided with multiple grooves at intervals, and each groove forms a reaction site. In this way, not only can the supporting ability for the reaction bottle be guaranteed, but the grooves can also further limit the position of the reaction bottle to ensure the accuracy of the storage position of the reaction bottle and limit the tilt angle of the reaction bottle to prevent the reaction bottle from tipping over and causing the raw materials stored inside to leak.

[0051] It should be further explained that in this invention, different reaction systems have different reaction conditions. Regardless of the reaction system, it is necessary to prevent the reactants from evaporating and to prevent interference from the external environment to ensure the accuracy of the reaction. Therefore, in a further embodiment of this invention, the base 1 also has a sealing station. The automated synthesis platform 100 further includes a sealing module 8 corresponding to the sealing station located on the base 1. The sealing module 8 includes a fixing structure 81 and a bottle cap feeding structure 82. The fixing structure 81 is located on the base 1 and is used to fix the reaction bottle and restrict the rotation of the reaction bottle along the vertically extending axis. The bottle cap feeding structure 82 is provided at intervals from the fixing structure 81 and includes a receiving part and a pushing part. The receiving part is located on the base 1 and forms a receiving cavity. The receiving cavity is used to hold the bottle cap. One end of the receiving part is connected to the receiving cavity to form a feeding position. The pushing part...The part is disposed in the receiving cavity and is located away from the feeding position. The pushing part is at least partially movable in the direction toward the feeding position so as to push the bottle cap to the feeding position.

[0052] In this embodiment, after the liquid addition structure 22 completes the reaction addition, the mechanical transfer arm 7 needs to transfer the reaction bottle to the sealing position. At this time, the fixing structure 81 can fix the reaction bottle at the sealing position and restrict the rotation of the reaction bottle. At this time, the mechanical transfer arm 7 moves to the feeding position of the receiving part to pick up the bottle cap at the feeding position, and then moves the bottle cap to align with the bottle mouth of the reaction bottle, presses down the bottle cap, and tightens the seal at the bottle mouth of the reaction bottle. After the reaction bottle is sealed, the mechanical transfer arm 7 transfers the sealed reaction bottle to the reaction position of the reaction module 4 as described on page 9 / 13 of the corresponding instruction manual 13 CN 122558404 A for reaction. The entire process does not require manual opening and sealing, which avoids contamination introduced by manual operation, prevents the volatilization of reactants during the reaction process, and isolates external impurities from interfering with the reaction system, further improving the degree of automation and the accuracy of experimental results.

[0053] Furthermore, after the mechanical transfer arm 7 picks up the bottle cap at the loading position, the pushing unit operates. The pushing unit can drive the new bottle cap stored in the receiving cavity to move towards the loading position, so that the new bottle cap is placed at the loading position. In this way, by continuously pushing the bottle cap to the loading position by the pushing unit, it can be ensured that the mechanical transfer arm 7 can pick up the bottle cap at the loading position every time, without the need for frequent manual replenishment, further reducing the frequency of manual intervention and improving the continuous operation capability of the platform.

[0054] It is understood that the pushing unit can be set in a variety of different structural forms. For example, the pushing unit can be set as a lead screw assembly, a cylinder assembly, or other structures. In actual settings, it can be selected according to the requirements.

[0055] Similarly, the fixing structure 81 can also be configured in various different structural forms. In one embodiment of the present invention, the fixing structure 81 includes a plurality of movable blocks 811, all of which are disposed on the base 1 and are at least partially movably arranged toward or away from each other. The plurality of movable blocks 811 are used to jointly clamp the reaction bottle. Each movable block 811 is also provided with a flexible abutment portion, which is used to contact the reaction bottle. With this configuration, the plurality of movable blocks 811 move synchronously toward each other, thus clamping and fixing the reaction bottle from multiple directions. At the same time, the flexible abutment portion can increase friction and improve clamping stability, and can also prevent the rigid structure from directly contacting and damaging the reaction bottle body, ensuring the integrity of the reaction bottle structure. The clamping operation is simple and reliable, and the positioning is accurate.High precision.

[0056] Of course, the number of the movable blocks 811 can be selected as two, three, four or other numbers according to the needs, and the present invention does not impose any restrictions.

[0057] It should be noted that when the movable blocks 811 are set to two, the two movable blocks 811 can be arranged in an arc shape in the direction facing each other. In this way, the two arc-shaped movable blocks 811 can better fit the body of the reaction bottle, increase the contact area, adapt to the body of the reaction bottle, improve the clamping stability, avoid the reaction bottle from rotating and slipping during the process of tightening the cap, ensure that the sealing operation can be completed smoothly, and have good structural adaptability.

[0058] In another embodiment of the present invention, the fixing structure 81 can also be configured as an elastic ring, which is arranged vertically upwards and downwards, and the inner diameter of the elastic ring gradually decreases from top to bottom. In this way, when the mechanical transfer arm 7 inserts the reaction bottle into the elastic ring from top to bottom, the elastic ring can tighten against the bottle body through its own elastic contraction. The elastic contraction force of the elastic ring can hold the reaction bottle body tightly, which can also achieve fixed positioning and anti-rotation. The structure is simpler, and the inclined inner wall can adapt to reaction bottles of different diameters. The structure is simpler, and there is no need to drive multiple structural actions, which reduces the structural complexity and control difficulty, lowers the cost, and makes it more convenient to use.

[0059] In other embodiments of the present invention, the fixing structure 81 can also be configured as other structural forms, which can be selected according to the requirements in actual settings.

[0060] The present invention also proposes a control method for an automated platform. This automated platform is based on an automated synthesis platform 100. The specific structure of this automated platform is as described in the above embodiments. Since the control method of this automated platform adopts all the technical solutions of all the above embodiments, it has at least all the beneficial effects brought about by the technical solutions of the above embodiments, which will not be described in detail here. Please refer to Figure 3. In the first embodiment of the present invention, the control method of the automated synthesis platform includes: S10, controlling the dispensing module 3 to add different raw materials to multiple raw material bottles; In this step, the dispensing module 3 can add different raw materials to different raw material bottles to ensure the variety and quantity of raw materials as described on pages 10 / 13 of the specification, CN 122558404 A, so that multiple raw material bottles can meet the raw material requirements of the reaction system corresponding to different experimental formulations.

[0061] S20. The reactant addition module 2 adds raw materials from multiple raw material bottles to a reaction flask according to multiple preset experimental formulas. In this step, the multiple preset experimental formulas are all different. When the reactant addition module 2 adds raw materials to the multiple reaction flasks, the type and ratio of raw materials in each reaction flask correspond to a preset experimental formula.The reaction system formed in each of the multiple reaction flasks is different, so that multiple parallel experiments can be carried out simultaneously.

[0062] S30: Control the mechanical transfer arm 7 to transfer the reaction flask to the reaction module 4, and control the reaction module 4 to regulate the reaction process in the reaction flask with preset reaction conditions; It can be understood that different reaction systems have different preset reaction conditions. By controlling the reaction module 4 to regulate the reaction process of multiple reaction flasks independently, the multiple reaction systems do not interfere with each other, and experiments under different conditions can be carried out simultaneously and in parallel, effectively improving experimental efficiency.

[0063] S40. Control the mechanical transfer arm 7 to transfer the reaction bottle to the characterization module 5, and simultaneously control the characterization module 5 to measure the physicochemical properties of the products in the reaction bottle; The characterization module 5 can perform automated characterization tests and data acquisition on the products after the chemical reaction is completed, and perform specified physicochemical property measurements (such as optical properties, electrochemical properties, etc.) on the products in different reaction bottles, and automatically transmit the measurement data to the host computer control system for recording and storage, so as to ensure the integrity and traceability of the data, without the need for manual recording of measurement results, which reduces the probability of errors in manual recording and further improves the automation level of the entire experimental process.

[0064] At the same time, all experimental data are centrally stored, which facilitates subsequent batch processing and analysis of data, quickly screens out reaction conditions that meet the requirements, and provides structured experimental data support for subsequent data-driven material performance prediction and optimization, improving the management efficiency and utilization value of experimental data.

[0065] S50. Control the mechanical transfer arm 7 to transfer the reaction bottle to the storage position of the storage module 6.

[0066] At this time, the reaction flasks that have completed the reaction and measurement can be stored in the storage module 6 and retrieved when needed later. The entire process requires no manual intervention, which can effectively avoid the product being contaminated by human error after the experiment. It also facilitates the subsequent review and secondary characterization of the product, further improving the standardization of the experimental process.

[0067] In addition, centralized storage also facilitates the unified batch processing of waste products, further reducing the workload of manual maintenance.

[0068] In the technical solution of this embodiment, when starting the raw material synthesis operation, firstly, the dispensing module 3 injects the raw materials from the multiple raw material tanks into the multiple raw material bottles, so that the multiple raw material bottles contain a variety of different raw materials. Then, the pipetting and adding structure 22 adds the different raw materials from the multiple raw material bottles into the reaction flasks according to the multiple different preset experimental formulas, according to the different amounts and contents, so that the multiple reaction flasks form a variety of different reaction systems. After the reactants are added, the mechanical transfer arm 7 operates to transfer the multiple reaction flasks.The reaction flasks are transferred from the reactant addition station to the reaction station. At this point, the reaction module 4 provides the required temperature and stirring conditions to each reaction flask according to different preset reaction conditions, thereby simultaneously achieving the parallel synthesis of multiple different reaction systems and greatly improving the platform's synthesis throughput. After the reaction is complete, the mechanical transfer arm 7 transfers multiple reaction flasks from the reaction station to the characterization station and places them in the characterization module 5. The characterization module 5 can automatically characterize and test the products after the chemical reaction in the reaction flasks and collect data. It also measures the specific physicochemical properties of the products in the reaction flasks according to different experimental formulations. After characterization, the mechanical transfer arm 7 transfers multiple reaction flasks to the storage module 6 and places them in multiple storage positions for storage; they can be retrieved later when needed. With this setup, the automated synthesis platform 100, through its modular layout of multiple independent workstations, can simultaneously support the parallel synthesis and characterization of multiple different reaction systems. Each workstation can operate independently without interfering with each other, which not only effectively improves the synthesis throughput and parallel processing capability, but also adapts to a variety of different synthesis schemes, possesses high scalability, and does not require customized modifications for specific reactions. This solves the problem of high coupling between existing platform hardware and target reactions, effectively improving the efficiency of material research and development.

[0069] Please refer to Figure 4. In the second embodiment of the present invention, before step S30, the method further includes: S21, controlling the mechanical transfer arm 7 to transfer the reaction flask to the sealing module 8; It should be noted that, in order to prevent the volatilization of reactants and interference from the external environment on the reaction, the reaction flask needs to be sealed before the reaction.

[0070] S22. The control fixing structure 81 fixes the reaction bottle, and at the same time controls the mechanical transfer arm 7 to pick up the bottle cap at the loading position; the fixing structure 81 can fix and restrict the rotation of the reaction bottle along the axial direction, so that the mechanical transfer arm 7 can align the bottle cap with the bottle mouth and tighten it, avoiding the reaction bottle rotating during the capping process and causing sealing failure.

[0071] S23. Control the mechanical transfer arm 7 to install the bottle cap to the bottle mouth of the reaction bottle.

[0072] After the mechanical transfer arm 7 aligns the bottle cap with the bottle mouth of the reaction bottle, it presses down and tightens it, thus completing the sealing operation of the reaction bottle.

[0073] In the technical solution of this embodiment, after the reactants are added, the sealing module 8 automatically completes the sealing of the reaction bottle, and then sends it into the reaction module 4 for reaction. The entire process does not require manual intervention in the sealing operation, which avoids the contamination of impurities introduced by manual contact with the reaction bottle, and also effectively prevents volatile reactants from escaping during the reaction process, thus ensuringThis ensures the safety of the experimenters and isolates the reaction system from the influence of external air, water vapor, and other impurities, further improving the stability of the reaction and the accuracy of the experimental results. It also further enhances the automation of the entire synthesis process, reducing manual intervention and allowing the automated synthesis platform to operate continuously and stably for extended periods, thus improving experimental efficiency.

[0074] Furthermore, in this invention, the automated synthesis platform 100 also includes a control device. The control device is electrically connected to the reactant addition module 2, the dispensing module 3, the reaction module 4, the characterization module 5, and the mechanical transfer arm 7. The control device includes a memory, a processor, and a control program for the automated synthesis platform 100 stored in the memory and executable on the processor. The control program for the automated synthesis platform 100 is configured to implement the steps of the control method for the automated synthesis platform described above.

[0075] Referring now to FIG5, a schematic diagram of a control device suitable for implementing embodiments of this application is shown. The control device in this application embodiment may include, but is not limited to, mobile terminals such as mobile phones, laptops, digital broadcast receivers, PDAs (Personal Digital Assistants), PADs (Portable Application Description), PMPs (Portable Media Players), vehicle terminals (e.g., vehicle navigation terminals), and fixed terminals such as digital TVs and desktop computers. The control device shown in the figure is merely an example and should not impose any limitations on the function and scope of use of the embodiments of this application.

[0076] As shown in FIG5, the control device may include a processing device 1001 (e.g., a central processing unit, a graphics processing unit, etc.), which can perform various appropriate actions and processes according to a program stored in a read-only memory (ROM) 1002 or a program loaded from a storage device 1003 into a random access memory (RAM) 1004. The RAM 1004 also stores various programs and data required for the operation of the control device. The processing device 1001, ROM 1002, and RAM 1004 are interconnected via a bus 1005. The input / output (I / O) interface 1006 is also connected to line A on page 12 / 13 of the general specification (CN 122558404). Typically, the following systems can be connected to the I / O interface 1006: input devices 1007, such as touchscreens, touchpads, keyboards, mice, image sensors, microphones, accelerometers, gyroscopes, etc.; and liquid crystal displays (LCDs).Output devices 1008 including displays, speakers, vibrators, etc.; storage devices 1003 including, for example, magnetic tapes, hard disks, etc.; and communication devices 1009. Communication devices 1009 can allow the control device to communicate wirelessly or wiredly with other devices to exchange data. Although control devices with various systems are shown in the figures, it should be understood that it is not required to implement or have all of the systems shown. More or fewer systems may be implemented or have instead.

[0077] In particular, according to the embodiments disclosed in this application, the processes described above with reference to the flowcharts can be implemented as computer software programs. For example, embodiments disclosed in this application include a computer program product comprising a computer program carried on a computer-readable medium, the computer program containing program code for performing the methods shown in the flowcharts. In such embodiments, the computer program can be downloaded and installed from a network via a communication device, or installed from storage device 1003, or installed from ROM 1002. When the computer program is executed by processing device 1001, the functions defined above in the methods of the embodiments disclosed in this application are performed.

[0078] The control device provided in this application, employing the control method of the automated synthesis platform in the above embodiments, can solve the technical problems of insufficient synthesis throughput, limited parallel synthesis capability, and inability to simultaneously accommodate multiple synthesis schemes in existing automated platforms. Compared with the prior art, the beneficial effects of the control device provided in this application are the same as those of the control method of the automated synthesis platform provided in the above embodiments, and other technical features in the control device are the same as those disclosed in the method of the previous embodiment, and will not be repeated here.

[0079] It should be understood that the various parts disclosed in this application can be implemented using hardware, software, firmware, or combinations thereof. In the description of the above embodiments, specific features, structures, materials, or characteristics can be combined in any suitable manner in one or more embodiments or examples.

[0080] The above descriptions are merely specific embodiments of this application, but the protection scope of this application is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this application should be included within the protection scope of this application. Therefore, the protection scope of this application should be determined by the protection scope of the claims.

[0081] The above description is merely an exemplary embodiment of the present invention and does not limit the patent scope of the present invention. Any equivalent structural transformations made using the contents of the specification and drawings of the present invention under the technical concept of the present invention, or direct / indirect applications in other related technical fields, are included within the patent protection scope of the present invention. Specification 13 / 13 pages 17 CN 122558404 A Figure 1 Specification Drawings 1 / 5 pages 18 CN 122558404 A Figure 2 Specification Drawings 2 / 5 pages 19CN 122558404 A Figure 3 Drawings of Description Page 3 / 5 20 CN 122558404 A Figure 4 Drawings of Description Page 4 / 5 21 CN 122558404 A Figure 5 Drawings of Description Page 5 / 5 22 CN 122558404 A Abstract The present application discloses an automated synthesis platform and a control method thereof. The automated synthesis platform comprises a base, a reactant addition module, an injection module, a reaction module, a characterization module, a storage module, and a mechanical transfer arm. The base is correspondingly provided with a reactant addition station, a sample injection station, a reaction station, a characterization station, and a storage station. The reactant addition module comprises a carrying structure and a pipetting addition structure. The carrying structure is configured to accommodate raw material bottles and reaction bottles, and the pipetting addition structure is arranged above the carrying structure for aspirating and adding raw materials. The injection module is configured to inject raw materials into the raw material bottles. Thereaction module is used for stirring and heating the reactants in the reaction bottles. The characterization module is used for measuring the products. The storage module corresponds to the storage station for storing the raw material bottles or reaction bottles. The mechanical transfer arm is disposed on the base and located among the plurality of stations for transferring the reaction bottles. With such an arrangement, both the synthesis throughput and parallel processing capability are improved, while high expandability is also achieved.

Claims

1. An automated synthesis platform, characterized in that, include: The base has reactant addition stations, sample dispensing stations, reaction stations, characterization stations, and storage stations arranged at intervals. The reactant addition module includes a support structure and a pipetting addition structure. The support structure is located on the base corresponding to the reactant addition station and is used to support multiple raw material bottles and multiple reaction bottles. The pipetting addition structure is spaced above the support structure and is movable in at least a first horizontal direction and a second horizontal direction. The pipetting addition structure is used to add raw materials from multiple raw material bottles into the reaction bottle according to the experimental formula. A dispensing module is located on the base corresponding to the sample dispensing station. The dispensing module is connected to multiple raw material tanks to dispense raw materials into multiple raw material bottles. A reaction module is disposed on the base corresponding to the reaction station. The reaction module is used to support the reaction bottle and to stir and heat the reactants in the reaction bottle. A characterization module is located on the base corresponding to the characterization station. The characterization module is used to sequentially hold multiple reaction flasks and measure the products in the reaction flasks. A storage module is disposed on the base corresponding to the storage station. The storage module has multiple storage positions, each of which is used to store one of the raw material bottles or one of the reaction bottles. as well as, A mechanical transfer arm is provided on the base and located between multiple workstations. The mechanical transfer arm is at least partially movable to multiple workstations to transfer the reaction flasks between the multiple workstations.

2. The automated synthesis platform as described in claim 1, characterized in that, The pipetting addition structure includes: A displacement platform includes a base, a first movable part, and a second movable part. The base is disposed on the pedestal and avoids the supporting structure. The first movable part is movably disposed on the base along a first horizontal direction and is located above the supporting structure. The second movable part is movably disposed on the first movable part along a second horizontal direction. A pipette is located in the second movable part and moves synchronously with the second movable part. The pipette is used to draw the raw material from the raw material bottle and add the raw material to the reaction bottle.

3. The automated synthesis platform as described in claim 2, characterized in that, The reactant addition module also includes a pipette tip replacement holder, which is spaced apart from the support structure and is used to support multiple pipette tips; The pipette includes a main body and a locking part. The main body is disposed on the second movable part, and the locking part is disposed on the main body. It has a locked state that locks the pipette tip to the main body, and an unlocked state that unlocks the pipette tip.

4. The automated synthesis platform as described in claim 3, characterized in that, The reactant addition module also includes a waste basket, which is disposed between the pipette tip replacement holder and the support structure and is located below the pipette. The upper end of the waste basket is open to receive the pipette tips removed from the pipette.

5. The automated synthesis platform as described in claim 1, characterized in that, The reaction module includes: A reaction stand having a plurality of spaced-apart reaction positions for holding a reaction flask; and, Multiple reaction processing units are provided, each corresponding to a reaction position on the reaction seat, and each reaction processing unit is configured to operate independently. Each reaction processing unit includes a stirring element and a heating element. The stirring element is used to stir the reactants in the reaction flask, and the heating element is used to regulate the temperature of the reaction system in the reaction flask.

6. The automated synthesis platform as described in claim 1, characterized in that, The base also has a sealing station; The automated synthesis platform further includes a sealing module disposed on the base corresponding to the sealing station, the sealing module comprising: A fixing structure is provided on the base, the fixing structure being used to fix the reaction flask and restrict the rotation of the reaction flask along an axis extending vertically; and, A bottle cap feeding structure, spaced apart from the fixed structure, includes a receiving part and a pushing part. The receiving part is located on the base and forms a receiving cavity for holding bottle caps. One end of the receiving part is connected to the receiving cavity to form a feeding position. The pushing part is located in the receiving cavity and is located away from the feeding position. At least part of the pushing part is movable in the direction toward the feeding position to push the bottle cap to the feeding position.

7. The automated synthesis platform as described in claim 6, characterized in that, The fixing structure includes multiple movable blocks, all of which are disposed on the base and are at least partially movably arranged in a direction toward or away from each other. The multiple movable blocks are used to jointly clamp the reaction bottle, and each movable block is also provided with a flexible abutment part for contacting the reaction bottle.

8. The automated synthesis platform as described in claim 1, characterized in that, The automated synthesis platform also includes a control device, which is electrically connected to the reactant addition module, the dispensing module, the reaction module, the characterization module, and the mechanical transfer arm. The control device includes a memory, a processor, and a control program for the automated synthesis platform stored in the memory and executable on the processor. The control program for the automated synthesis platform is configured to implement the steps of the control method for the automated synthesis platform.

9. A control method for an automated synthesis platform, characterized in that, Based on the automated synthesis platform as described in any one of claims 1 to 8, the control method of the automated synthesis platform includes: The control module dispenses different raw materials into multiple raw material bottles; The reactant addition module adds raw materials from multiple raw material bottles to the reaction flask according to multiple preset experimental formulas; The mechanical transfer arm is controlled to transfer the reaction flask to the reaction module, and the reaction module is controlled to regulate the reaction process in the reaction flask according to preset reaction conditions. The mechanical transfer arm is controlled to transfer the reaction flask to the characterization module, and the characterization module is controlled to measure the physicochemical properties of the products in the reaction flask. The mechanical transfer arm is controlled to transfer the reaction flask to the storage location of the storage module.

10. The control method for the automated synthesis platform as described in claim 9, characterized in that, The base also has a sealing station; The automated synthesis platform further includes a sealing module disposed on the base corresponding to the sealing station, the sealing module comprising: A fixing structure is provided on the base, the fixing structure being used to fix the reaction flask and restrict the rotation of the reaction flask along an axis extending vertically; and, A bottle cap feeding structure, spaced apart from the fixed structure, includes a receiving part and a pushing part. The receiving part is located on the base and forms a receiving cavity for holding bottle caps. One end of the receiving part is connected to the receiving cavity to form a feeding position. The pushing part is located in the receiving cavity and is located away from the feeding position. At least part of the pushing part is movable in the direction toward the feeding position to push the bottle cap to the feeding position. Before the step of controlling the mechanical transfer arm to transfer the reaction flask to the reaction module and simultaneously controlling the reaction module to regulate the reaction process within the reaction flask under preset reaction conditions, the method further includes: The mechanical transfer arm is controlled to transfer the reaction flask to the sealing module; The control and fixing structure fixes the reaction flask, while the mechanical transfer arm picks up the bottle cap at the loading position. The mechanical transfer arm is controlled to install the bottle cap onto the mouth of the reaction flask.

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