Preparation method for kras g12d intermediate

HK40138635APending Publication Date: 2026-10-09SHANGHAI SENHUI MEDICINE CO LTD +2

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Patent Information

Application Number: HK62026126300
Authority / Receiving Office: HK · HK
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2023-07-13
Filing Date: 2026-07-17
Publication Date: 2026-10-09
Estimated Expiration: 2044-07-11

Application Information

Patent Timeline

13 Jul 2023

Priority

17 Jul 2026

Application

HK62026126300

09 Oct 2026

Publication

HK40138635A

IPC: C07C41/24; A61P35/00

Inventors: JIANG, WEI; GAO, JUNFENG

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Abstract

The invention relates to a preparation method of a KRAS G12D intermediate. Specifically, the method for preparing the compound as shown in the formula (V-1) is simple in preparation process route, and the cost can be remarkably reduced.

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Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202480040122.5 (22) Application Date 2024.07.12 (66) Domestic Priority Data 202310855917.9 2023.07.13 CN (85) PCT International Application Entering National Phase Date 2025.12.16 (86) PCT International Application Application Data PCT / CN2024 / 105153 2024.07.12 (87) PCT International Application Publication Data WO2025 / 011634 ZH 2025.01.16 (71) Applicant Shanghai Senhui Pharmaceutical Co., Ltd. Address 201203 4th Floor, Building 14, No. 3728 Jinke Road, Shanghai Pudong New Area Free Trade Zone Applicant: Shanghai Shengdi Pharmaceutical Co., Ltd. Jiangsu Hengrui Medicine Co., Ltd. (72) Inventors: Jiang Wei, Gao Junfeng, Zhou Yinan, Jiang Jun, Huang Jian (74) Patent Agency: Beijing Gecheng Intellectual Property Agency Co., Ltd. 11314 Patent Attorney: Cheng Wei (51) Int.Cl. C07C 41 / 24 (2006.01) A61P 35 / 00 (2006.01) (54) Invention Name: Method for Preparing KRAS G12D Intermediate (57) Abstract: A method for preparing KRAS G12D intermediate. Specifically, a method for preparing the compound shown in formula (V-1), the preparation process route is simple and can significantly reduce costs. CN 121399088 A 2026.01.23 CN 1 21 39 90 88 A