Compound containing pyrazole ring and bicyclic heteroaryl group, pharmaceutical composition thereof and use thereof

HK40138689APending Publication Date: 2026-10-09CHIA TAI TIANQING PHARMA GRP CO LTD
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Patent Information

Application Number
HK62026126761
Authority / Receiving Office
HK · HK
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-12-09
Filing Date
2026-07-28
Publication Date
2026-10-09
Estimated Expiration
2044-12-11
Patent Text Reader

Abstract

The invention belongs to the field of medicinal chemistry, and relates to a compound containing pyrazole ring and bicyclic heteroaryl, and the structure is shown as a formula (I). The invention also relates to a preparation method of the compound, a pharmaceutical composition containing the compound and application of the compound in treatment of related diseases (such as cancer or immune diseases).
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Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202480074854.6 (22) Application Date 2024.12.12 (66) Domestic Priority Data 202311716882.7 2023.12.13 CN 202411548739.6 2024.11.01 CN 202411799022.9 2024.12.09 CN (85) PCT International Application Entering National Phase Date 2026.05.26 (86) PCT International Application Application Data PCT / CN2024 / 138866 2024.12.12 (87) PCT International Application Publication Data WO2025 / 124496 ZH 2025.06.19 (71) Applicant: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Address: No. 369, Yuzhou South Road, Lianyungang City, Jiangsu Province, 222062, China (72) Inventors: Liu Fei, Feng Taotao, Meng Qingyi, Xu Hongjiang, Shi Wei, Bi Cheng (51) Int.Cl. C07D 403 / 12 (2006.01) A61K 31 / 41 (2006.01) A61P 35 / 00 (2006.01) (54) Invention Title: Compounds Containing Pyrazole Ring and Bicyclic Heteroaryl Group, Pharmaceutical Compositions Thereof and Uses (57) Abstract: This disclosure belongs to the field of medicinal chemistry and relates to compounds containing pyrazole ring and bicyclic heteroaryl group, with the structure shown in formula (I). This application also relates to methods for preparing said compounds, pharmaceutical compositions containing said compounds, and their use in treating related diseases (e.g., cancer or immune diseases). CN 122341599 A 2026.07.03 CN 1 22 34 15 99 A