Composition including nipa palm extract and fucoidan extract for reducing skin swelling
Patent Information
- Application Number
- HK62026126974
- Authority / Receiving Office
- HK · HK
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-08-25
- Filing Date
- 2026-08-03
- Publication Date
- 2026-10-09
- Estimated Expiration
- 2044-06-12
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Abstract
Description
(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202480050456.0 (22) Application Date 2024.06.13 (30) Priority Data 10-2023-0112273 2023.08.25 KR (85) PCT International Application Entering National Phase Date 2026.01.30 (86) PCT International Application Application Data PCT / KR2024 / 008144 2024.06.13 (87) PCT International Application Publication Data WO2025 / 048157 KO 2025.03.06 (71) Applicant: Kolmar Holdings Co., Ltd. Address: Sejong City, South Korea (72) Inventors: Park Byung-cheol, Kim Seul-gi, Kim Yoo-ah, Choi Hyung, Yoon Sang-hyun, Moon Byung-seok (74) Patent Agency: Chengdu Fandian Intellectual Property Agency Co., Ltd. 51258 Patent Attorney: Song Dongying (51) Int.Cl. A23L 33 / 105 (2006.01) A23L 33 / 125 (2006.01) A61K 8 / 9794 (2006.01) A61K 8 / 73 (2006.01) A61K 8 / 02 (2006.01) A61Q 19 / 00 (2006.01) A61Q 90 / 00 (2006.01) (54) Invention Title: Composition for Improving Skin Swelling Containing Water Coconut Extract and Fucoidan Extract (57) Abstract: This invention relates to a composition for improving skin swelling containing water coconut extract and fucoidan extract. Specifically, the composition has excellent effects in relieving swelling, improving hydration, improving elasticity, and improving firmness in more than one aspect. Claims 1 page Description 11 pages Drawings 8 pages CN 121620301 A 2026.03.06 CN 1 21 62 03 01 A 1. A composition for improving skin swelling, characterized in that it contains water coconut extract and fucoidan extract. 2. The composition for improving skin swelling according to claim 1, characterized in that the water coconut extract is extracted with hot water or ethanol. 3. The composition for improving skin swelling according to claim 1, characterized in that the fucoidan extract is extracted with hot water. 4. The composition for improving skin swelling according to claim 1, characterized in that the water coconut extract and fucoidan extract are in the form of dried powder. 5. The composition for improving skin swelling according to claim 1, characterized in that the composition comprises the water coconut extract and fucoidan extract in a weight ratio of 1:0.5 to 2.6. The composition for improving skin swelling according to claim 1, characterized in that the composition comprises the water coconut extract and fucoidan extract in a 1:1 weight ratio. 7. The composition for improving skin swelling according to claim 1, characterized in that the water coconut extract and fucoidan extract comprise 40 to 70% by weight of the total weight of the composition. 8. The composition for improving skin swelling according to claim 1, characterized in that the composition has excellent effects in relieving swelling, improving moisturizing, improving elasticity, and improving firmness in one or more aspects. 9. A food composition, characterized in that it comprises the composition according to claims 1 to 8. 10. A cosmetic material composition, characterized in that it comprises the composition according to claims 1 to 8. Claims 1 / 1 Page 2 CN 121620301 A Composition for Improving Skin Swelling Containing Water Coconut Extract and Fucoidan Extract Technical Field
[0001] This invention relates to a composition for improving skin swelling containing water coconut extract and fucoidan extract, specifically, to a composition that has excellent effects in relieving swelling by containing water coconut extract and fucoidan extract as active ingredients. Background Art
[0002] Skin swelling is a phenomenon caused by excessive accumulation of water or salt in the skin, which reduces the skin's elasticity and moisturizing ability, becoming a cause of skin wrinkles and aging. When skin swelling worsens, cracking or reduced skin elasticity and luster can occur, increasing wrinkles.
[0003] It is understood that this skin swelling phenomenon is caused by various reasons, such as lack of water, excessive salt intake, stress, increased reactive oxygen species, lack of sleep, allergic reactions, hormonal imbalances, etc.
[0004] Although various products, such as functional foods or cosmetics, have been launched on the market to improve skin swelling, most of them are not very effective, or cause skin irritation due to physical pressure or chemical ingredients.
[0005] On the other hand, as people's demand for products using natural substances that are non-irritating and do not cause problems is increasing, a large amount of research is being conducted to explore natural materials and improve their efficacy. In addition, in recent years, active research has been conducted on mixtures of two or more natural extracts, utilizing the functions of various natural extracts. However, when extracts are mixed, problems such as precipitation, unstable dosage forms, and decreased user experience may occur, and the desired efficacy may not be fully achieved.
[0006] Therefore, the inventors have conducted continuous research to develop compositions that improve skin swelling by utilizing complexes of natural extracts. The results confirm that compositions with excellent effects in relieving skin swelling, improving hydration, improving elasticity, and improving firmness can be prepared by including water coconut extract and fucoidan extract as active ingredients, thus completing the present invention.
[0007] Summary of the Invention Problem to be Solved The object of the present invention is to provide a composition that, by including water coconut extract and fucoidan extract as active ingredients, has excellent effects in relieving skin swelling, improving hydration, improving elasticity, and improving firmness.
[0008] The technical problem of the present invention is not limited to the above-mentioned technical problems. Other technical problems not mentioned can be clearly understood by those skilled in the art from the following description.
[0009] Means for Solving the Problem According to embodiments of the present invention, a composition for improving skin swelling is provided, comprising water coconut extract and fucoidan extract.
[0010] Effects of the Invention The composition according to the present invention is characterized by having excellent effects in relieving skin swelling, improving skin hydration, improving skin elasticity, and improving skin firmness. Instruction Manual 1 / 11 Page 3 CN 121620301 A Description of Drawings
[0011] To more fully understand the drawings referenced in the detailed description of the invention, a brief description of each drawing will be provided below.
[0012] FIG1 is a graph showing the antioxidant effect (radical scavenging ability) of the examples and comparative examples.
[0013] FIG2 is a graph showing the reduction of swelling in both cheeks, both lower legs, and both ankles before and two weeks after administration in the placebo control group, E-001 group, and E-002 group.
[0014] FIG3 is a photograph showing the results of FIG2.
[0015] FIG4 is a graph showing the improvement of internal skin hydration in both cheeks and both backs of hands before and two weeks after administration in the placebo control group, E-001 group, and E-002 group. Figure 5 shows the improvement in skin elasticity of both cheeks, both backs of hands, and both calves before and two weeks after administration in the placebo-controlled group, the E-001 group, and the E-002 group. Figure 6 shows the improvement in skin firmness of both cheeks, both backs of hands, and both calves before and two weeks after administration in the placebo-controlled group, the E-001 group, and the E-002 group.
[0016] Figure 7 is a photograph showing the results of Figure 6. Detailed Description
[0017] According to an embodiment of the present invention, a composition for improving skin swelling comprising water coconut extract and fucoidan extract is provided.
[0018] Furthermore, the water coconut extract may be extracted with hot water or with ethanol.
[0019] Furthermore, the fucoidan extract may be extracted with hot water.
[0020] Furthermore, the coconut water extract and the fucoidan extract may be in the form of dried powder.
[0021] Furthermore, the coconut water extract and the fucoidan extract may be contained in a weight ratio of 1:0.5 to 2.
[0022] Furthermore, the coconut water extract and the fucoidan extract may be contained in a weight ratio of 1:1.
[0023] Furthermore, based on the total weight of the composition, 40 to 70% by weight of the coconut water extract and the fucoidan extract may be contained.
[0024] Furthermore, the composition may have excellent effects in relieving swelling, improving moisturizing, improving elasticity, and improving firmness in more than one aspect.
[0025] Furthermore, a food composition comprising the composition is provided.
[0026] Furthermore, a cosmetic material composition comprising the composition is provided.
[0027] Specific Embodiments Unless otherwise defined, all technical and scientific terms used in this specification have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. Generally, the nomenclature used in this specification is well-known and commonly used in the technical field. When describing embodiments of the present invention, detailed descriptions of related well-known configurations or functions will be omitted if they would obscure the understanding of the embodiments of the present invention. Furthermore, embodiments of the present invention will be described below; however, the technical concept of the present invention is not limited thereto, and various modifications and implementations can be made by those skilled in the art.
[0028] In this specification, when a part is described as "including" a certain constituent element, unless there is a particularly contrary statement, it means that other constituent elements may also be included, rather than excluding other constituent elements. The term "and / or" includes a combination of multiple related listed items or any one of multiple related listed items. Specification 2 / 11 pages 4 CN 121620301 A
[0029] According to an embodiment of the present invention, a composition for improving skin swelling is provided, comprising Nypa fruticans extract and fucoidan extract.
[0030] Nypa fruticans is the only species of the subfamily Nypa Cocosinae, a monotypic subfamily of the palm family, and is distributed in South Asia, Southeast Asia and Oceania. Water coconut, the young shoot of the coconut tree, is rich in polyphenols, thus possessing antioxidant, blood circulation-promoting, anti-inflammatory, and anti-cancer effects. Furthermore, it is rich in vitamin E and saponins, which help treat cardiovascular diseases, cataracts, and arthritis, and also relieve constipation, eliminate toxins, and alleviate hangovers.
[0031] Fucoidan is a sulfated high-molecular-weight polysaccharide with a viscous structure, present in trace amounts in brown algae such as wakame and kelp. It is a component that protects seaweed from the effects of seawater flow or external stimuli, acting as a protective film to defend against microorganisms in the ocean.
[0032] In this invention, "extract" refers to a substance obtained by extracting components from a natural substance. It is a broad concept, including both components dissolved in a solvent extracted from a natural substance using water or organic solvents, and components obtained by extracting only specific components from a natural substance. Extracts may include all extracts, fractionation products, their dilutions, concentrates, or dried products obtained in the steps of extraction, fractionation, or refining.
[0033] In this invention, the extraction methods for extracts may use extraction methods commonly used in the art, such as hot water extraction, ethanol extraction, maceration extraction, cold maceration extraction, reflux extraction, supercritical fluid extraction, subcritical water extraction, solvent extraction, pressing, high-temperature extraction, high-pressure extraction, or ultrasonic extraction. Specifically, hot water extraction or ethanol extraction can be used, but is not limited thereto.
[0034] According to the embodiments, the solvent used for the extract can be water, ethanol, or a mixture thereof, specifically, purified water, ethanol, or alcohol. However, it is not limited thereto, and various solvents suitable in the art can be used alone or in combination. For example, the following can be used as extraction solvents: water (or distilled water); lower alcohols with 1 to 4 carbon atoms such as methanol, ethanol, propanol, and butanol; polyols such as propylene glycol, butanediol, hexanediol, methylpropanediol, glycerol, butanediol, propylene glycol, pentanediol, and dipropylene glycol; and hydrocarbon solvents such as methyl acetate, ethyl acetate, acetone, benzene, hexane, diethyl ether, and dichloromethane; or mixtures thereof.
[0035] In the embodiments, the water coconut extract can be extracted with hot water or ethanol.
[0036] In the embodiments, the fucoidan extract can be extracted with hot water.
[0037] Hot water extraction involves extracting the active ingredient using hot water at 60 to 140°C. Since pure water is used as the extraction medium, its advantage is that it avoids problems caused by the toxicity of the organic solvents used during extraction.
[0038] According to an embodiment, the extract can be a liquid dosage form or a dry powder. In this case, the drying method can be not only freeze-drying, but also various methods commonly used in this technical field, such as vacuum drying, hot air drying, and spray drying.
[0039] According to an embodiment, the extract can be prepared or processed by various methods such as vacuum distillation or concentration.
[0040] The composition of the present invention includes both coconut palm extract and fucoidan extract, and the composition has the effect of improving skin swelling, specifically, it has one or more effects of relieving swelling, improving moisturizing, improving elasticity, and improving firmness. When coconut palm extract and fucoidan extract are used in combination, superior effects can be obtained compared to using coconut palm extract alone or using fucoidan extract alone.
[0041] The composition of the present invention may contain coconut palm extract and fucoidan extract in a weight ratio of 1:0.5 to 2. When coconut palm extract and fucoidan extract are contained in the above mixing ratio, excellent effects can be achieved in relieving swelling, improving moisturizing, improving elasticity, or improving firmness.
[0042] In an embodiment, coconut palm extract and fucoidan extract may be mixed in a weight ratio of 1:1. In this case, the effects of relieving swelling, improving moisturizing, improving elasticity, or improving firmness can be maximized. However, this is not a limitation. Instructions 3 / 11 Page 5 CN 121620301 A
[0043] In an embodiment, the composition may contain 40 to 70% by weight of the water coconut extract and fucoidan extract based on the total weight of the composition. When the water coconut extract and fucoidan extract are contained in the said amounts, excellent skin swelling improvement effects can be observed. However, it is not limited thereto.
[0044] In an embodiment, the composition may have excellent effects in one or more aspects of relieving swelling, improving moisturizing, improving elasticity, and improving firmness. Specifically, the composition of the present invention can relieve skin swelling by inhibiting factors that cause skin swelling by improving the moisturizing properties of the skin and increasing elasticity and firmness.
[0045] In an embodiment, a food composition containing the composition is provided.
[0046] In this specification, "food" means food made and processed using raw materials or ingredients that have functional benefits to the human body, meaning that in addition to providing nutrition, it is processed to effectively exert the body's regulatory functions and has high medical and therapeutic effects. It may be used in combination with terms well known in the art such as functional foods. For example, it can be prepared as a health functional food, a health supplement food, a food for special nutritional supplementation, a functional beverage, etc., or the composition according to the present invention can be added to natural foods, processed foods, etc. The food can be prepared as powder, granules, tablets, capsules, syrups or beverages, etc., and there are no restrictions on the form in which the food can take, and it can include all foods in the general sense.
[0047] For example, it can be beverages and various drinks, fruits and their processed foods (canned fruits, jams, etc.), fish, meat and their processed foods (ham, bacon, etc.), bread and noodles, biscuits and snacks, dairy products (butter, cheese, etc.), etc., and can include all functional foods in the general sense.In addition, it may include food used as animal feed.
[0048] The food composition according to the invention may be prepared by further including food additives and other suitable auxiliary ingredients that are generally permitted in the art. For example, it may also contain flavoring agents, natural carbohydrates, sweeteners, vitamins, electrolytes, coloring agents, pectic acid, alginic acid, organic acids, protective colloid thickeners, pH adjusters, stabilizers, preservatives, glycerin, alcohols, carbonation agents, etc.
[0049] For example, as flavoring agents, natural flavoring agents containing semaphore, stevia extract, etc. or synthetic flavoring agents containing saccharin, aspartame, etc. may be used; natural carbohydrates may include: monosaccharides such as glucose and fructose; disaccharides such as maltose and sucrose; polysaccharides such as dextrin and cyclodextrin; sugar alcohols such as xylitol, sorbitol, and erythritol; as sweeteners, natural sweeteners such as semaphore and stevia extract or synthetic sweeteners such as saccharin and aspartame may be used. Preferably, the food additives and other auxiliary ingredients are added in very small amounts to achieve the desired effect. When expressed numerically, a very small amount can refer to a range of approximately 0.0005% by weight to about 0.5% by weight based on the total weight of the product composition. The mixing amount of the ingredients can be readily selected by those skilled in the art without impairing the purpose and effect of the invention.
[0050] In an embodiment, a cosmetic material composition comprising the composition is provided. In this invention, "skin" refers to tissue covering the surface of an animal body and is a broad concept, including not only tissue covering the face or body but also the scalp.
[0051] According to an embodiment, when the composition of the present invention is used as a cosmetic material composition, it can be prepared into various products that are effective in improving swelling, improving skin hydration, increasing skin elasticity, and improving skin firmness.
[0052] According to an embodiment, the composition of the present invention can be prepared into functional cosmetics such as nourishing creams, essences, ampoules, or basic cosmetics such as lotions and creams. In addition, it can be made into soap, detergent, facial cleansing cream, cleansing water, etc., or into makeup products such as lipstick, lip balm, mascara, blush, shading powder, highlighter, makeup base, foundation, pressed powder, concealer, and concealer cream (skin instruction manual 4 / 11 page 6 CN 121620301 A cover).In addition, it can be prepared into products that are applied to the skin, such as facial masks and hydrogel slimming patches, or into products that are sprayed onto the skin, such as mists and aerosols.
[0053] According to embodiments, the cosmetic material composition of the present invention can be provided in dosage forms commonly prepared in the art. For example, it can be provided in dosage forms such as solutions, emulsions obtained by dispersing an oil phase in an aqueous phase, emulsions obtained by dispersing an aqueous phase in an oil phase, suspensions, emulsions, solids, gels, oils, powders, pastes, or foam aerosols.
[0054] According to embodiments, other ingredients commonly used in the art may also be included without impairing the effects of the present invention, such as thickeners, pH adjusters, isotonic agents, surfactants, stabilizers, preservatives, antiseptics, ultraviolet absorbers, bactericides, humectants, retardants, antioxidants, organic pigments, inorganic pigments, fragrances, vitamins, etc. The mixing amounts of the components can be readily selected by those skilled in the art without impairing the purpose and effects of the invention.
[0055] Hereinafter, examples and experimental examples will be provided to illustrate the invention in more detail, but the invention is not limited thereto.
[0056] Preparation of the hot water extract of coconut water: For each gram (g) of coconut water, add ten times its volume of distilled water and extract by boiling water at 95±2°C for 6 hours. Remove the solids from the extract obtained by boiling water extraction and concentrate under reduced pressure. After concentration, mix with dextrin at a ratio of 7:3 and spray dry to obtain the hot water extract of coconut water.
[0057] Preparation of the ethanol extract of coconut water: For each gram (g) of coconut water, add ten times its volume of 50% ethanol and set the extraction temperature to 70°C. In the first extraction, extract for 4 hours at ten times (v / w) of the solvent ratio of the sample, and in the second extraction, extract for 2 hours at ten times (v / w) of the solvent ratio of the sample. After extraction, the extract to which solids have been removed is concentrated using a vacuum concentrator, and then freeze-dried to obtain a water-coconut ethanol extract.
[0058] Preparation of fucoidan hot water extract: Dried wakame seaweed is extracted with purified water, and after solid-liquid separation, the extract is concentrated to prepare a first concentrate. After removing alginic acid from the concentrate, a second concentration is performed. Then, ethanol is added and impregnated according to the detailed polysaccharide separation process, and the precipitate is refined. After refining, it is dissolved in water and freeze-dried to prepare a fucoidan hot water extract.
[0059] Experimental Example 1: Antioxidant Activity Assay (DPPH Radical Scavenging Assay) Compositions containing only the prepared hot water extract of coconut water, ethanol extract of coconut water, or hot water extract of fucoidan were used as Preparation Examples 1 to 3, and compositions mixed according to the ratios in Table 1 below were used as Preparation Examples 4 to 9. On the other hand, Vitamin C was used as Comparative Example 1.
[0060] Table 1 Specification 5 / 11 pages 7 CN 121620301 A
[0061] To detect the antioxidant activity of the preparation examples and comparative examples, the DPPH radical scavenging ability was determined. After dissolving DPPH powder in ethanol to prepare a 0.5 mM DPPH solution, 100 μL of the preparation example and the comparative example were added to each of the 96-well plates. 100 μL of 99% ethanol was added to the DPPH non-reaction zone, and 100 μL of 0.5 mM DPPH was added to the DPPH reaction zone. The absorbance was detected at 540 nm.
[0062] Figure 1 is a graph showing the antioxidant effects (free radical scavenging capacity) of the preparation examples and comparative examples. By observing Figure 1, the antioxidant effect was confirmed in all preparation examples. In particular, preparation examples 4 to 9, which mixed the extracts, showed excellent antioxidant effects compared to preparation examples 1 to 3, which contained only coconut water extract or fucoidan extract. Furthermore, preparation examples 5 and 8, which mixed coconut water extract and fucoidan extract in a 1:1 ratio, had even better antioxidant effects compared to the other preparation examples.
[0063] Experimental Example 2: Skin Swelling Test Clinical trials were conducted using preparation examples 5 and 8, which showed the best antioxidant effects.
[0064] Adult men and women aged 20 to 60 years (final effective number of participants: 61, mean age: 43.541 years, 6 males and 55 females) were randomly assigned to a placebo control group and an experimental group, and a skin swelling test was performed. Both the experimental group and the placebo control group took 1000 mg of tablets twice daily (morning and evening) prepared according to the ingredients in Table 2 below for two weeks.
[0065] The E-001 group refers to the experimental group that took a composition of a 1:1 mixture of water coconut hot water extract and fucoidan hot water extract (Preparation Example 5), and the E-002 group refers to the experimental group that took a composition of a 1:1 mixture of water coconut ethanol extract and fucoidan hot water extract (Preparation Example 8). The placebo control group took placebo tablets of the same shape as the experimental group. Unlike the water coconut ethanol extract, the water coconut hot water extract had dextrin added during the spray drying process. Therefore, Preparation Example 5 contained 35.7143% by weight of water coconut extract based on the total weight of the composition, such that the mixing ratio of the active ingredients was 1:1, as in Preparation Example 8.
[0066] Table 2 Instruction Manual 6 / 11 pages 8 CN 121620301 A
[0067] The degree of improvement in swelling was detected in the test subjects before and after administration.
[0068] Specifically, using Antera 3D CS (Miravex, Ireland) as a 3D skin imaging device, images were taken of both eyelids, both cheeks, and both backs of hands of the placebo control group, E-001 administration group, and E-002 administration group before and after administration. Based on the saved images (Elevation-Custom mode), skin volume (mm³) values within a specific range were analyzed and detected. The smaller the value, the more effective the treatment in improving swelling.
[0069] Regarding skin swelling of the lower legs, ankles, and dorsum of the feet, the Vectra XT / Vectra ectra H2 (Canfield Imaging Systems, Canfield, USA), which can detect skin volume by 3D imaging, was used to take pictures of both lower legs, both ankles, and both dorsum of the feet before and after administration. The volume (cc) values were analyzed and detected based on the saved images. The smaller the value, the more effective it is in relieving swelling.
[0070] The detection results are shown in Table 3 below.
[0071] Table 3 Instruction manual 7 / 11 pages 9 CN 121620301 A
[0072] Based on the data, Figure 2 shows the improvement results of skin swelling of both cheeks, both lower legs, and both ankles before and two weeks after administration in the placebo control group, E-001 group, and E-002 group. In addition, to visually confirm the swelling reduction effect, images taken before and after administration are shown in Figure 3. Specifically, in Figure 3(a), part (a) is a photograph of the left eyelid before and after administration, part (b) is a photograph of the left cheek before and after administration, part (c) is a photograph of the back of the left hand before and after administration, and in Figure 3(b), part (d) is a photograph of the lower leg before and after administration, and part (e) is a photograph of the ankle and instep before and after administration.
[0073] Referring to Table 3, Figures 2 and 3, there was no statistically significant difference in the placebo control group compared with before administration, while there was a statistically significant difference in the E-001 and E-002 administration groups compared with before administration, showing a significant reduction. That is, it can be confirmed that there is a statistically significant difference between the E-001 and E-002 administration groups compared with the placebo control group. Furthermore, the photographs confirmed that there was no change in the placebo control group, while the swelling was significantly reduced in both the E-001 and E-002 groups before and after administration.
[0074] Therefore, it can be seen that the composition of the present invention is effective in improving swelling of the entire skin, including the eyelids, cheeks, backs of hands, lower legs, ankles, and dorsum of feet.
[0075] Experimental Example 3: Detection of Intradermal Moisture Content The subjects of Experimental Example 2 were used as subjects to detect the intradermal moisture content.
[0076] Regarding the intradermal moisture content, a skin moisture meter (MoistureMeter D Compact, Delfin Technologies Ltd, Finland) was used to detect the moisture content of both eyelids, both cheeks, both backs of hands, both lower legs, both ankles, and both dorsum of feet before and after administration in the placebo control group, the E-001 group, and the E-002 group. The parameter is the tissue dielectric constant (TDC) value, and the unit is %, and the detected value is proportional to the moisture content.
[0077] The detection results are shown in Table 4 below.
[0078] Table 4, Specification 8 / 11 pages, 10 CN 121620301 A
[0079] Based on the data, Figure 4 shows the results of the detection of the water content inside the skin of both cheeks and both backs of the hands before and two weeks after administration in the placebo control group, the E-001 group, and the E-002 group.
[0080] Referring to Table 4 and Figure 4, there was no statistically significant difference in the placebo control group compared with before administration two weeks after administration, while there was a statistically significant difference in the E-001 group and the E-002 group compared with before administration two weeks after administration, showing a significant reduction. That is, it can be confirmed that there is a statistically significant difference between the E-001 group and the E-002 group compared with the placebo control group.
[0081] Therefore, it can be seen that the composition of the present invention is effective in improving swelling by reducing the water content inside the skin that causes swelling.
[0082] Experiment 4: Skin Elasticity Test The subjects of Experiment 2 were used as subjects to test skin elasticity.
[0083] Regarding the skin elasticity test of the eyelids, cheeks, and backs of the hands, a skin elasticity tester (Cutometer MPA580, Courage+Khazaka electronic GmbH, Germany) was used to test the elasticity of both eyelids, both cheeks, and both backs of the hands before and after administration in the placebo control group, the E-001 group, and the E-002 group. The test was performed three times, and the average value was used as the skin elasticity evaluation data. The R² value, which represents the skin's re-deformation capacity, is the overall elasticity. The closer this value is to 1, the greater the elasticity, and the measured value is directly proportional to the skin elasticity.
[0084] Regarding the detection of skin elasticity of the calves, ankles, and dorsum of the feet, the elasticity of both sides of the calves, ankles, and dorsum of the feet was detected using a Ballistometer BLS780 (DIA STRON, UK) before and after administration to the placebo control group, the E-001 group, and the E-002 group. The tests were performed three times, and the average value was used as the skin elasticity evaluation data. The detection parameter was CoR, and the detection value was directly proportional to skin elasticity.
[0085] The test results are shown in Table 5 below. Figure 5 is a graph showing the improvement in skin elasticity of both sides of the cheeks, backs of both hands, and calves before and two weeks after administration to the placebo control group, the E-001 group, and the E-002 group.
[0086] Table 5 Specification 9 / 11 pages 11 CN 121620301 A
[0087] Referring to Table 5 and Figure 5, for the placebo control group, there was no statistically significant difference after two weeks of use compared to before use, while for the E-001 and E-002 groups, there was a statistically significant difference after two weeks of use compared to before use, showing a significant increase. That is, it can be confirmed that there is a statistically significant difference between the E-001 and E-002 groups compared to the placebo control group.
[0088] Therefore, it can be seen that the composition of the present invention is effective in improving skin elasticity.
[0089] Experimental Example 5: Detection of Skin Tightness The skin tightness of the subjects in Experimental Example 2 was detected.
[0090] Regarding the detection of skin firmness, a skin scanner (DUB-USB, TPM taberna pro medicum, Germany) was used to detect images of the subjects' cheeks, backs of hands, calves, and feet before and after administration, and the skin firmness was analyzed. The parameter is density, expressed as a percentage, and the detected value is directly proportional to the skin firmness.
[0091] The detection results are shown in Table 6 below. Figure 6 is a graph showing the improvement in skin firmness of the placebo control group, E-001 group, and E-002 group before and two weeks after administration. Figure 7 shows photographs of the detection results. (a) is a photograph of the left cheek before and after administration, and (b) is a photograph of the right calf before and after administration.
[0092] Table 6 Specification 10 / 11 pages 12 CN 121620301 A
[0093] Referring to Table 6, Figure 6 and Figure 7, for the placebo control group, there was no statistically significant difference after two weeks of use compared to before use, while the E-001 and E-002 groups showed statistically significant differences after two weeks of use compared to before use, indicating a significant increase. That is, it can be confirmed that, compared to the placebo control group, the E-001 and E-002 groups showed statistically significant differences after two weeks of use compared to before use. In addition, it can also be confirmed from the photographs that there was no change in the placebo control group, while the E-001 and E-002 groups showed significant improvement in skin firmness before and after use.
[0094] Therefore, it can be seen that the composition of the present invention is effective in improving skin firmness.
[0095] The specific parts of the present invention have been described above in detail. It will be clear to those skilled in the art that these specific techniques are merely preferred embodiments and are not intended to limit the scope of the present invention. Therefore, the essential scope of the present invention should be defined by the appended claims and their equivalents. Instruction manual 11 / 11 page 13 CN 121620301 A Figure 1 Instruction manual Figure 1 / 8 page 14 CN 121620301 A Figure 2 Instruction manual Figure 2 / 8 page 15 CN 121620301 A Figure 3a Instruction manual Figure 3 / 8 page 16 CN 121620301 A Figure 3b Instruction manual Figure 4 / 8 page 17 CN 121620301 A Figure 4 Instruction manual Figure 5 / 8 page 18 CN 121620301 A Figure 5 Instruction manual Figure 6 / 8 page 19 CN 121620301 A Figure 6 Instruction manual Figure 7 / 8 page 20 CN 121620301 A Figure 7 Instruction manual Figure 8 / 8 page 21 CN 121620301 A.
Claims
1. A composition for improving skin swelling, characterized in that, it comprises a water coconut extract and a fucoidan extract.
2. The composition for improving skin swelling according to claim 1, characterized in that, the water coconut extract is extracted with hot water or ethanol.
3. The composition for improving skin swelling according to claim 1, characterized in that, the fucoidan extract is extracted with hot water.
4. The composition for improving skin swelling according to claim 1, characterized in that, the water coconut extract and the fucoidan extract are in a dried powder form.
5. The composition for improving skin swelling according to claim 1, characterized in that, the water coconut extract and the fucoidan extract are contained in the composition in a weight ratio of 1:0.5 to 2.
6. The composition for improving skin swelling according to claim 1, characterized in that, the water coconut extract and the fucoidan extract are contained in the composition in a weight ratio of 1:
1.
7. The composition for improving skin swelling according to claim 1, characterized in that, the water coconut extract and the fucoidan extract are contained in the composition in a weight ratio of 40 to 70% based on the total weight of the composition.
8. The composition for improving skin swelling according to claim 1, characterized in that, the composition has an excellent effect in one or more of the aspects of alleviating swelling, improving moisturization, improving elasticity, and improving firmness.
9. A food composition, characterized in that, it comprises the composition according to claims 1 to 8.
10. A cosmetic material composition, characterized in that, it comprises the composition according to claims 1 to 8.