COMBINATION OF SAMBILOTO EXTRACT, BLACK CUMIN AND PROPOLIS AS AN IMMUNOMODULATOR FOR TB

Abstract

COMBINATION OF SAMBILOTO EXTRACT, BLACK CUMIN AND PROPOLIS AS AN IMMUNOMODULATOR FOR TB This invention concerns a combination formula of extracts from sambiloto extract, black cumin and propolis with a concentration of 450 mg / kgBW (1:1:1) that can stimulate the immune system in mice infected with Mycobacterium tuberculosis intraperitoneally. The purpose of this invention is to overcome pre-existing problems, especially tuberculosis caused by Mycobacterium tuberculosis bacterial infection.. where the combination of sambiloto extract, black cumin and propolis as an immunomodulator of TB disease. This invention is supported by various examinations including examination of white blood cells, interleukin 6, interleukin 10, and histopathology of lung tissue in mice infected with M. tuberculosis bacteria.