Microbiocidal derivatives

Abstract

82138 FF 53 ABSTRACT MICROBIOCIDAL DERIVATIVES Compounds of the formula (I)5 R 8 R 1 R 7 R 6 R 5 R 4 R 3 R 2 N O N A F N S O (I) wherein the substituents are as defined in claim 1, useful as pesticides, and especially fungicides.

Description

The present invention relates to microbiocidal thiazole derivatives, e.g., as active ingredients,which have microbiocidal activity, in particular fungicidal activity. The invention also relates to thepreparation of these thiazole derivatives, to agrochemical compositions which comprise at least one ofthe thiazole derivatives and to uses of the thiazole derivatives or compositions thereof in agriculture orhorticulture for controlling or preventing the infestation of plants, harvested food crops, seeds or non-living materials by phytopathogenic microorganisms, preferably fungi.WO 2010 / 012793 and WO 2017 / 207362 describe thiazole derivatives as pesticidal agents.According to the present invention, there is provided a compound of formula (1):whereinAis C-Hor N;R1 is C1-CaalkoxyC1-Czalkyl, C1-C6alkylsulfanylC1-C6alkyl, C1-CsalkylsulfinylC+-Cealkyl, Ci-CealkylsulfonylC1-Cealkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5- or 6-memberednon-aromatic monocyclic ring comprising 1, 2 or 3 heteroatoms individually selected from nitrogen,oxygen and sulfur;RZis hydrogen or halogen;R3 is C1-Csalkyl;R4, R5 R6 are each independently hydrogen or C1-C4alkyl;R7 is hydrogen, C1-Caalkyl, C1-CsalkoxycarbonylC1-Caalkyl, C1-Csalkoxycarbonyl, or Ci-Cealkoxy;R3 is hydrogen, C1-C6alkoxyC1-C6alkycarbonyl, C1-C6alkylsulfanylC1-Csalkylcarbonyl, Ci-CealkylsulfinylC1-Csalkycarbonyl, C1-CsalkylsulfonylC1-Csalkycarbonyl, or heterocyclylcarbonyl, whereinthe heterocyclyl moiety is a 4-, 5- or 6-membered non-aromatic monocyclic ring comprising 1, 2 or 3heteroatoms individually selected from nitrogen, oxygen and sulfur;or a salt or an N-oxide thereof.According to a second aspect of the invention, there is provided an agrochemical compasitioncomprising a fungicidally effective amount of a compound of formula (I) according to the presentinvention. Such an agricultural composition may further comprise at least one additional active ingredientand / or an agrochemically-acceptable diluent or carrier.According to a third aspect of the invention, there is provided a method of controlling or preventinginfestation of useful plants by phytopathogenic microorganisms, wherein a fungicidally effective amountof a compound of formula (I), or a composition comprising this compound as active ingredient, is appliedto the plants, to parts thereof or the locus thereof.According to a fourth aspect of the invention, there is provided the use of a compound of formula(I) as a fungicide. According to this particular aspect of the invention, the use may or may not includemethods for the treatment of the human or animal body by surgery or therapy.As used herein, the term "halogen" refers to fluorine (fluoro), chlorine (chloro), bromine (bromo)or iodine (iodo).As used herein, the term "C+-Csalkyl" refers to a straight or branched hydrocarbon chain radicalconsisting solely of carbon and hydrogen atoms, containing no unsaturation, having from one to eightcarbon atoms, and which is attached to the rest of the molecule by a single bond. "C1-Csalkyl", "Ci-Caalkyl" and "Cs-Csalkyl" are to be construed accordingly. Examples of C+-Csalkyl include, but are notlimited to, methyl, ethyl, n-propyl, and the isomers thereof, for example, iso-propyl. A "C+-Cealkylene"group refers to the corresponding definition of C1-Cealkyl, except that such radical is attached to the restof the molecule by two single bonds.As used herein, the term "C1-Csalkoxy" refers to a radical of the formula -ORa where Ra is a Ci-Cealkyl radical as generally defined above. The terms "C1-Cqalkoxy" and "C1-Csalkoxy" are to beconstrued accordingly. Examples of C1-C6alkoxy include, but are not limited to, methoxy, ethoxy, 1-methylethoxy (iso-propoxy), and propoxy.As used herein, the term "C1-CealkoxyC1-Csalkyl" refers to a radical of the formula ReORa- whereinRy is a C1-Csalkyl radical as generally defined above, and Ra. is a C1-Csalkylene radical as generallydefined above. "C1-CsalkoxyC1-Csalkyl", "C1-CasalkoxyC1-Caalkyl", *"C1-CaalkoxyC1-C6alkyl", "Ci-CaalkoxyC1-Czaalkyl", and "Cs-CsalkoxyCq-Czalkyl" are to be construed accordingly. Examples of Ci-CealkoxyC1-Csalkyl include, but are not limited to isopropoxymethyl, tert-butoxymethyl, 1-methoxyethyl,1-isopropoxyethyl, 1-tert-butoxyethyl.As used herein, the term "C+-Csalkoxycarbonyl" refers to a radical of the formula RaOC(O)-,wherein Ra is a C1-Csalkyl radical as generally defined above. "C1-Csalkoxycarbonyl" and "Ci-Caalkoxycarbonyl" are to be construed accordingly.As used herein, the term "C1-CsalkoxycarbonylC1-Caalkyl" refers to a radical of the formulaR.OC(O)Rw-, wherein Ra is a C1-Csalkyl radical as generally defined above, and Re is a C1-Caalkyleneradical as generally defined above.As used herein, the term "C1-CsalkoxyC1-Csalkycarbonyl" refers to a radical of the formulaRaORLC(0)-, wherein Ra is a C1-Csalkyl radical as generally defined above, and Re is a C1-C6alkyleneradical as generally defined above.As used herein, the term "Cy-CsalkylsulfanylCq-Csalkyl" refers to a radical of the formula RaSRp-,wherein Ra is a C1-Csalkyl radical as generally defined above, and Ry is a C1-C6alkylene radical asgenerally defined above.As used herein, the term "C1-CsalkylsulfinylC+-Cealky!" refers to a radical of the formula RaS(O)Rs-, wherein Ra is a C1-C6alkyl radical as generally defined above, and Rs is a C1-Csalkylene radical asgenerally defined above.As used herein, the term "C1-CsalkylsulfanylC1-Csalkylcarbonyl" refers to a radical of the formulaRaSReC(O)-, wherein Ra is a C+-Cealkyl radical as generally defined above, and Rp is a C1-C6alkyleneradical as generally defined above.As used herein, the term "C1-CsalkylsulfinylC1-Csalkylcarbonyl" refers to a radical of the formulaRaS(O)RpC(O)-, wherein Ra is a C1-Csalkyl radical as generally defined above, and Ry is a C1-Csalkyleneradical as generally defined above.As used herein, the term "C1-CsalkylsulfonylC1-Csalkylcarbonyl" refers to a radical of the formulaRaS(0)2RuC(O)-, wherein Ra is a C1-Cealkyl radical as generally defined above, and Ry is a Ci-Cealkylene radical as generally defined above.As used herein, the term "heterocyclyl" refers to a stable 4-, 5- or 6-membered non-aromaticmonocyclic ring which comprises 1, 2 or 3 heteroatoms, wherein the heteroatoms are individuallyselected from nitrogen, oxygen and sulfur. The heterocyclyl radical may be bonded to the rest of themolecule via a carbon atom or heteroatom. Examples of heterocyclyl include, but are not limited to,aziridinyl, azetidinyl, oxetanyl, thietanyl, tetrahydrofuryl, pyrrolidinyl, pyrazolidinyl, imidazolidnyl,piperidinyl, piperazinyl, morpholinyl, dioxolanyl, dithiolanyl and thiazolidinyl.As used herein, the term "heterocyclylcarbonyl" refers to a radical of the formula RaC(O)-, whereinRa is a heterocyclyl moiety as defined above.The presence of one or more possible asymmetric carbon atoms in a compound of formula (I)means that the compounds may occur in optically isomeric forms, i.e., enantiomeric or diastereomericforms. Also, atropisomers may occur as a result of restricted rotation about a single bond. Formula (I) isintended to include all those possible isomeric forms and mixtures thereof. The present inventionincludes all those possible isomeric forms and mixtures thereof for a compound of formula (I). Likewise,formula (1) is intended to include all possible tautomers. The present invention includes all possibletautomeric forms for a compound of formula (1).In each case, the compounds of formula (I) according to the invention are in free form, in oxidizedform as an N-oxide, or in salt form, e.g., an agronomically usable salt form.N-oxides are oxidized forms of tertiary amines or oxidized forms of nitrogen-containingheteroaromatic compounds. They are described for instance in the book "Heterocyclic N-oxides" by A.Albini and S. Pietra, CRC Press, Boca Raton (1991).The following list provides definitions, including preferred definitions, for substituents A, R", R?,R3, R*, R5 RS, R"and R with reference to compounds of Formula (1). For any one of these substituents,any of the definitions given below may be combined with any definition of any other substituent givenbelow or elsewhere in this document.Ais C-H ar N. In one set of embodiments, A is C-H. In another set of embodiments, A is N.R' is C1-CaalkoxyC1-Caalkyl, C1-CsalkylsulfanylC1-Csalkyl, C1-CsalkylsulfinylC1-Csalkyl, Ci-CealkylsulfonylC1-C6alkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5- or 6-memberednon-aromatic monocyclic ring comprising 1, 2 or 3 heteroatoms individually selected from nitrogen,oxygen and sulfur.Preferably, R' is C1-CsalkoxyC1-Czalkyl, C1-CaalkylsulfanylC+-Caalkyl, C1-CaalkylsulfinyICi-Casalkyl, C1-CaalkylsulfonylC+-Casalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5-, or 6-membered non-aromatic monocyclic ring comprising 1 or 2 heteroatoms individually selected fromnitrogen and oxygen.More preferably, R' is C1-CaalkoxyC1-Czalkyl, C1-CaalkylsulfanylC-Caalkyl, C1-Caalkylsulfiny|Ci-Caalkyl, C+-CsalkylsulfonylC+-Caalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5- or 6-membered non-aromatic monocyclic ring comprising a single oxygen atom.More preferably still, R' is Ca-CsalkoxyC1-Czalkyl, C1-CaalkylsulfanylC1-Caalkyl, Ci-CsalkylsulfinylC1-Caalkyl, C1-CsalkylsulfonylC1-C6alkyl, or heterocyclyl, wherein the heterocyclyl moietyis a 4-, 5-, or 6-membered non-aromatic monocyclic ring comprising 1 or 2 heteroatoms individuallyselected from nitrogen and oxygen.Even more preferably still, R' is isopropoxymethyl, tert-butoxymethyl, 1-methoxyethyl, 1-isopropoxyethyl, 1-tert-butoxyethyl, C1-CsalkylsulfanylC1-Csalkyl, Cq-CzalkylsulfinylC1-Csalkyl, Ci-CaalkylsulfonylC1-Csalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5-, or 6-memberednon-aromatic monocyclic ring comprising 1 or 2 heteroatoms individually selected from nitrogen andoxygen.In a further preferable embodiment, R' is isopropoxymethyl, tert-butoxymethyl, 1-methoxyethyl,1-isopropoxyethyl, 1-tert-butoxyethyl, 1-methylsulfonylethyl, oxetane-3-yl, tetrahydrofuran-2-yl,tetrahydrofuran-3-yl, or tetrahydropyran-4-yl.In one embodiment, R' is C1-CsalkoxyC1-C6alkyl, C1-CsalkylsulfanylCs-Cealkyl, Ci-CealkylsulfinylC1-Csalkyl, C1-CsalkylsulfonylC1-Csalkyl, or heterocyclyl, wherein the heterocyclyl moietyis a 4-, 5- or 8-membered non-aromatic monocyclic ring comprising 1, 2 or 3 heteroatoms individuallyselected from nitrogen, oxygen and sulfur.Preferably, R' is C1-CasalkoxyC1-Caalkyl, C1-CaalkylsulfanylC1-Caalkyl, C1-CaalkylsulfinylCi-Caalkyl, C1-CaalkylsulfonylC+-Caalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5- or 6-membered non-aromatic monocyclic ring comprising 1 or 2 heteroatoms individually selected fromnitrogen, oxygen and sulfur.More preferably, R' is C1-CsalkoxyC1-Csalkyl, C1-CsalkylsulfanylC+-Caalkyl, C1-CaalkylsulfinyICi-Caalkyl, C+-CsalkylsulfonylC1-Csalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4- or 5-membered non-aromatic monocyclic ring comprising 1 or 2 heteroatoms individually selected fromnitrogen and oxygen.Even more preferably, R' is C1-CsalkoxyC1-Csalkyl, C1-CsalkylsulfanylC-Caalkyl, Ci-CsalkylsulfinylC1-Caalkyl, C1-CsalkylsulfonylCq-Csalkyl, or heterocyclyl, wherein the heterocyclyl moietyis a 4- or 5-membered non-aromatic monocyclic ring comprising a single oxygen atom.Even more preferably still, R' is isopropoxymethyl, tert-butoxymethyl, 1-methoxyethyl, 1-isopropoxyethyl, 1-tert-butoxyethyl, 1-methylsulfanylethyl, 1-methylsulfinylethyl, 1-methylsulfonylethyl,oxetane-3-yl, tetrahydrofuran-2-yl, or tetrahydrofuran-3-yl.Most preferably, R" is isopropoxymethyl, tert-butoxymethyl, 1-methoxyethyl, 1-isopropoxyethyl,1-methylsulfonylethyl, oxetane-3-yl, tetrahydrofuran-2-yl, or tetrahydrofuran-3-yl.In one set of embodiments, R' is C1-CsalkylsulfanylC1-Csalkyl, C1-CsalkylsulfinylC1-Csalkyl, Ci-CealkylsulfonylC+-Cealkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5- or 6-memberednon-aromatic monocyclic ring comprising 1, 2 or 3 heteroatoms individually selected from nitrogen,oxygen and sulfur.In another set of embodiments, R' is C1-CsalkylsulfanylC1-Csalkyl, C1-CaalkylsulfinylCq-Caalkyl,C1-CaalkylsulfonylC1-Caalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5- ar 6-memberednon-aromatic monocyclic ring comprising 1 or 2 heteroatoms individually selected from nitrogen, oxygenand sulfur.In a further set of embodiments, R' is C1-CaalkylsulfanylC1-Caalkyl, C1-CaalkylsulfinylC1-Caalkyl,C1-CsalkylsulfonylC1-Csalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5-, or 6-memberednon-aromatic monocyclic ring comprising 1 or 2 heteroatoms individually selected from nitrogen andoxygen.In a further set of embodiments, R! is C1-CsalkylsulfanylC1-Csalkyl, C1-Csalkylsulfiny|C1-Csalkyl,C1-CsalkylsulfonylC1-Csalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4- or 5-memberednon-aromatic monocyclic ring comprising 1 or 2 heteroatoms individually selected from nitrogen andoxygen.In a further still set of embodiments, R' is C:-CsalkylsulfanylC+-Caalkyl, Cq-CsalkylsulfinyICs-Csalkyl, C+-CsalkylsulfonylC+-Csalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4- or 5-membered non-aromatic monocyclic ring comprising a single oxygen atom.In a preferable set of embodiments, R' is 1-methylsulfonylethyl, oxetane-3-yl, tetrahydrofuran-2-yl, tetrahydrofuran-3-yl, or tetrahydropyran-4-yl.In a more preferable set of embodiments, R' is 1-methylsulfanylethyl, 1-methylsulfinylethyl, 1-methylsulfonylethyl, oxetane-3-yl, tetrahydrofuran-2-yl, or tetrahydrofuran-3-yl.In a most preferable set of embodiments, R' is 1-methylsulfonylethyl, oxetane-3-yl,tetrahydrofuran-2-yl, or tetrahydrofuran-3-yl.In a further set of preferable embodiments, R' is Cs-CsalkoxyC1-Czalkyl, C1-CsalkylsulfanylCi-Caalkyl, C1-CsalkylsulfinylCq-Caalkyl, C1-CaalkylsulfonylC1-Caalkyl, or heterocyclyl, wherein theheterocyclyl moiety is a 4- or 5--membered non-aromatic monocyclic ring comprising 1 or 2 heteroatomsindividually selected from nitrogen and oxygen.Preferably, R" is isopropoxymethyl, tert-butoxymethyl, 1-isopropoxyethyl, 1-tert-butoxyethyl, 1-methylsulfanylethyl, 1-methylsulfinylethyl, 1-methylsulfonylethyl, oxetane-3-yl, tetrahydrofuran-2-yl, ortetrahydrofuran-3-yl. More preferably, R" is isopropoxymethyl, tert-butoxymethyl, 1-isopropoxyethyl, 1-methylsulfonylethyl, oxetane-3-yl, tetrahydrofuran-2-yl, or tetrahydrofuran-3-yl.R? is hydrogen or halogen. Preferably, R? is hydrogen, chloro, bromo or fluoro. More preferably,R2 is hydrogen or fluoro. In one set of embodiments, R? is hydrogen. In a further set of embodiments,R1 is fluoro.R1 is C1-Cgalkyl. Preferably, R is C1-C6alkyl. More preferably, R is C1-Caalkyl. Even morepreferably, R is methyl, ethyl or isopropyl. Most preferably, R? is methyl.R* R R are each independently hydrogen or C1-Csalkyl. Preferably, R*, R% R are eachindependently hydrogen or C1-Caalkyl. More preferably, R*, R*, R are each independently hydrogen ormethyl.In one set of embodiments, R* is hydrogen, and R and R are both methyl.R" is hydrogen, C1-Caalkyl, C1-CsalkoxycarbonylCq-Caalkyl, C1-Cealkoxycarbonyl, or C1-Csalkoxy.Preferably, R" is hydrogen, C1-Caalkyl, C1-CaalkoxycarbonylC1-Caalkyl, C1-Caalkoxycarbonyl, or Ci-Csalkoxy. More preferably, RY is hydrogen, C1-Csalkyl, C1-CsalkoxycarbonylC1-Coalkyl, Ci-Caalkoxycarbonyl, or C1-Csalkoxy. Even more preferably, R' is hydrogen, methyl,methoxycarbonylmethyl, methoxycarbonyl, or methoxy. More preferably still, R7 is hydrogen or methyl,most preferably, R7 is hydrogen.R is hydrogen, C1-CsalkoxyC1-Csalkycarbonyl, C1-CsalkylsulfanylC1-Csalkylcarbonyl, Ci-CealkylsulfinylC1-Csalkycarbonyl, C1-CsalkylsulfonylC1-Csalkycarbonyl, or heterocyclylcarbonyl, whereinthe heterocyclyl moiety is a 4-, 5- or 6-membered non-aromatic monocyclic ring comprising 1, 2 or 3heteroatoms individually selected from nitrogen, oxygen and sulfur.Preferably, R is hydrogen, C1-CaalkoxyC1-Caalkycarbonyl, C1-CaalkylsulfanylCq-Csalkylcarbonyl,C1-CaalkylsulfinylC1-Caalkycarbonyl, C1-CaalkylsulfonylC1-Casalkycarbonyl, or heterocyclylcarbonyl,wherein the heterocyclyl moiety is a 4-, 5- or 6-membered non-aromatic monocyclic ring comprising 1or 2 heteroatoms individually selected from nitrogen, oxygen and sulfur.More preferably, R is hydrogen, C1-CsalkoxyC1-Csalkycarbonyl, C1-CaalkylsulfanylCi-Csalkylcarbonyl, C4-CsalkylsulfinylC+-Caalkycarbonyl, C1-CsalkylsulfonylCq-Csalkycarbonyl, orheterocyclylcarbonyl, wherein the heterocyclyl moiety is a 4- or 5-membered non-aromatic monocyclicring comprising 1 or 2 heteroatoms individually selected from nitrogen and oxygen.Even more preferably, R is hydrogen, or heterocyclylcarbonyl, wherein the heterocyclyl moietyis a 4- or 5-membered non-aromatic monocyclic ring comprising a single oxygen atom.Even more preferably still, R is hydrogen or tetrahydrofuran-3-carbonyl. Most preferably, R ishydrogen.In a compound of formula (I) according to the present invention, preferably:Ais C-HorN;R' is Ca-CasalkoxyC1-Caalkyl, C1-CsalkylsulfanylC1-Csalkyl, C1-CaalkylsulfinylC1-Csalkyl, Ci-CaalkylsulfonyIC+-Csalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4- ar 5-memberednon-aromatic monocyclic ring comprising a single oxygen atom;R2 is hydrogen or fluoro;R is methyl;R* RS, and R are each independently hydrogen or methyl;R" is hydrogen; andR is hydrogen or heterocyclylcarbonyl, wherein the heterocyclyl moiety is a 4- or 5-memberednon-aromatic monocyclic ring comprising a single oxygen atom.More preferably, A is N;R' is Ca-CasalkoxyC1-Caalkyl, C1-CsalkylsulfanylC1-Caalkyl, C1-CaalkylsulfinylC1-Caalkyl, Ci-CsalkylsulfonylC+-Csalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4- or 5-memberednon-aromatic monocyclic ring comprising a single oxygen atom,R? is hydrogen or fluoro;R? is methyl;R*, R, and R are each independently hydrogen or methyl;R" is hydrogen; andR? is hydrogen or tetrahydrofuranyl.Even mare preferably, A is N;R! is C1-CaalkylsulfanylCs-Csalkyl, C1-CsalkylsulfinylC1-Csalkyl, C1-CaalkylsulfonylCq-Csalkyl, orheterocyclyl, wherein the heterocyclyl moiety is a 4- or 5-membered non-aromatic monocyclic ringcomprising a single oxygen atom;R? is hydrogen or fluoro;R is methyl;R* is hydrogen;R* and RE? are both methyl;R" is hydrogen; andR? is hydrogen.In a further set of preferable embodiments, in a compound of formula (I) according to the presentinvention, preferably, Ais N;R!' is C1-CaalkoxyC1-Czalkyl, C1-CsalkylsulfanylC1-Csalkyl, C1-CsalkylsulfinylC1-Csalkyl, Ci-CealkylsulfonylC+-Csalkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5- or 6-membered non-aromatic monocyclic ring comprising 1, 2 or 3 heteroatoms individually selectedfrom nitrogen, oxygen and sulfur;R? is hydrogen or fluoro;R3 is methyl;R* is hydrogen;R and R are both methyl;R" is hydrogen; andR is hydrogen.More preferably, Ais N;R! is isopropoxymethyl, tert-butoxymethyl, 1-methoxyethyl, 1-isopropoxyethyl, 1-tert-butoxyethyl.C1-CsalkylsulfanylC+-Czalkyl, C+-CsalkylsulfinylC+-Csalkyl, C1-CsalkylsulfonylCq-Csalkyl, orheterocyclyl, wherein the heterocyclyl moiety is a 4-, 5-, or 8-membered non-aromatic monocyclicring comprising 1 or 2 heteroatoms individually selected from nitrogen and oxygen;R? is hydrogen or fluoro;R? is methyl;R* is hydrogen;R and RE are both methyl;R" is hydrogen; andR? is hydrogen.Preferably, the compound of formula (I) is selected from:2-[(2,6-difluoro-4-pyridyl)-(tetrahydrofuran-3-carbonyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-N-(tetrahydrofuran-3-carbonyl)thiazole-4-carboxamide (P-1);2-[(2,6-difluoro-4-pyridyl)-(tetranydrofuran-2-carbonyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-2);2-[(2,6-difluoro-4-pyridyl)-(tetrahydrofuran-3-carbonyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-3);2-[(2,6-difluoro-4-pyridyl)-(oxetane-3-carbonyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-4);2-[2-tert-butoxypropanoyl-(2,6-difluoro-4-pyridyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-5);2-[(2,6-difluoro-4-pyridyl)-(2-isopropoxypropanoyl)aminc]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-6);2-[(2-tert-butoxyacetyl)-(2,6-difluoro-4-pyridyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-7);2-[(2,6-difluoro-4-pyridyl)-(2-isopropoxyacetyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-8);2-[(2,6-difluoro-4-pyridyl)-(2-methoxypropanoyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-9);2-[(2,6-difluoro-4-pyridyl)-(2-methylsulfonylpropanoylyamino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-10); and2-[(2,6-difluoro-4-pyridyl)-(tetrahydropyran-4-carbanyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (P-11).Compounds of the present invention can be made as shown in the following schemes, in which,unless otherwise stated, the definition of each variable is as defined above for a compound of Formula(1).The compounds of formula (1a) according to the invention, wherein R', R?, R, R* R, R and R'are as defined for formula (1), and R is hydrogen, can be obtained by transformation of a compound offormula (Il), wherein A. R?, R, R* R, R and R' are as defined for formula (1), with a compound offormula (111), wherein R'is as defined for formula (I) and Xa is halogen, preferably bromo or chloro, eitherby thermal heating, or with the aid of a base. This is shown in Scheme 1 (below).Scheme 1Those skilled in the art will recognise that the conditions used to prepare compounds of formula(la) will depend on the stoichiometry of the reaction. For example, reacting 1-1.5 equivalents ofcompounds of formula (Ill) with 1 equivalent of compounds of formula (Il) will generate predominantlycompounds of formula (la), whereas reacting 2-2.1 equivalents of compounds of formula (111) with 1equivalent of compounds of formula (Il) will generate compounds of formula (Ib), wherein R is Ci-CealkoxyC1-Csalkycarbonyl, C+-CealkylsulfanylC1-Csalkylcarbonyl, C1-C6alkylsulfinylC1-Csalkycarbonyl,C1-CsalkylsulfonylC1-Csalkycarbonyl, or heterocyclylcarbonyl, wherein the heterocyclyl is a 4-, 5- or 6-membered non-aromatic monocyclic ring comprising 1, 2 or 3 heteroatoms individually selected fromnitrogen, oxygen and sulfur. This is illustrated in Scheme 2 (below).Scheme 2The compounds of formula (II), wherein A, R?, R, R* RS, R, and R' are as defined for formula(1), can be obtained by transformation of a compound of formula (IV), wherein A and R? are as definedfor formula (1), with a compound of formula (V), wherein R, R*, R, R, and R" are as defined for Formula(I) and Xb is halogen, preferably bromo or chloro, either by thermal heating, or with the aid of a base orunder the conditions of the transition metal catalysed Buchwald-Hartwig amination. This is shown inScheme 3 (below). Such compounds of formula (Il) have been described in WO 2019 / 105933.Scheme 3The compounds of formula (V), wherein R, R*, R, R, and R' are as defined for formula (I) andXb is halogen, preferably bromo or chloro, can be obtained by transformation of a compound of formula(VI), wherein R? is as defined for formula (1) and Xb is halogen, preferably bromo, and a compound offormula (VII), wherein R*, R%, R, and R' is as defined for formula (1), either via an intermediate acidchloride or directly with a peptide coupling agent. This is shown in Scheme 4 (below).Scheme 4The compounds of formula (VI), wherein R? is as defined for formula (I) and Xb is halogen,preferably bromo or chloro, can be obtained by transformation of a compound of Formula (VIII), whereinR3 is as defined for formula (I), Xb is halogen, preferably bromo or chloro, and R? is C1-Csalkyl, and abase. This is shown in Scheme 5 (below).Scheme 5Alternatively, the compounds of formula (Il), wherein R? and A are as defined for formula (I), can beobtained by transformation of a compound of formula (IX), wherein R%, R?, and A are as defined forformula (I), with a compound of formula (VII), wherein R4, R5, R6, and R7 are as defined for formula (1),either via an intermediate acid chloride or directly with an peptide coupling agent. This is shown inScheme 6 (below).Scheme 6The compounds of formula (IX), wherein R?, A and R are as defined for formula (1), can beobtained by transformation of a compound of formula (X), wherein R?, Rand A are as defined forformula (I) and R' is C1-Csalkyl, with a base. This is shown in Scheme 7 (below).Scheme 7The compounds of formula (X), wherein R2, A, and R are as defined for formula (I) and R' is Ci-Csalkyl, can be obtained by transformation of a compound of formula (IV), wherein A and R? are asdefined for formula (I), with a compound of formula (VII), wherein R is as defined for formula (I), Xb ishalogen, preferably bromo or chloro, and R' is C1-Csalkyl, either by thermal heating, or with the aid ofa base or under the conditions of the transition metal catalysed Buchwald-Hartwig amination. This isshown in Scheme 8 (below).Scheme 8Alternatively, the compounds of formula (X), wherein R2, A, and R? are as defined for formula (|)and R' is C1-Csalkyl, can be obtained by transformation of a compound of formula (XI), wherein R? andA are as defined for formula (I) and Xc is halogen, preferably bromo or iodo, with a compound of formula(XI), wherein R is as defined for formula (I) and R'is C1-Csalkyl, under the conditions of the transitionmetal catalysed Buchwald-Hartwig amination. This is shown in Scheme 9 (below).Scheme 9Alternatively, the compounds of formula (Il), wherein A, R?, R, R*, R%, R, and R" are as definedfor formula (I), can be obtained by transformation of a compound of formula (XI), wherein A and R? areas defined for formula (I) and Xc is halogen, preferably bromo aor iodo, with a compound of formula (XIII),wherein R¥, R* R RS, and R' are as defined for formula (I), either by thermal heating, or with the aid ofa base or under the conditions of the transition metal catalysed Buchwald-Hartwig amination. This isshown in Scheme 10 (below).Scheme 10Surprisingly, it has now been found that the novel compounds of formula (I) have, for practicalpurposes, a very advantageous level of biological activity for protecting plants against diseases that arecaused by fungi.The compounds of formula (I) can be used in the agricultural sector and related fields of use, e.g..as active ingredients for controlling plant pests or on non-living materials for control of spoilagemicroorganisms or organisms potentially harmful to man. The novel compounds are distinguished byexcellent activity at low rates of application, by being well tolerated by plants and by beingenvironmentally safe. They have very useful curative, preventive and systemic properties and may beused for protecting numerous cultivated plants. The compounds of formula (I) can be used to inhibit ordestroy the pests that occur on plants or parts of plants (fruit, blossoms, leaves, stems, tubers, roots) ofdifferent crops of useful plants, while at the same time protecting also those parts of the plants that growlater, e.g., from phytopathogenic microorganisms.The present invention further relates to a method for controlling or preventing infestation of plantsor plant propagation material and / or harvested food crops susceptible to microbial attack by treatingplants or plant propagation material and / or harvested food crops wherein an effective amount acompound of formula (I) is applied to the plants, to parts thereof or the locus thereof.It is also possible to use the compounds of formula (I) as fungicide. The term "fungicide" as usedherein means a compound that controls, modifies, or prevents the growth of fungi. The term "fungicidallyeffective amount" means the quantity of such a compound or combination of such compounds that iscapable of producing an effect on the growth of fungi. Controlling or modifying effects include alldeviation from natural development, such as killing, retardation and the like, and prevention includesbarrier or other defensive formation in or on a plant to prevent fungal infection.It is also possible to use compounds of formula (I) as dressing agents for the treatment of plantpropagation material, e.g., seed, such as fruits, tubers or grains, or plant cuttings (e.g., rice), for theprotection against fungal infections, as well as against phytopathogenic fungi occurring in the soil. Thepropagation material can be treated with a composition comprising a compound of formula (1) beforeplanting: seed, e.g., can be dressed before being sown.The active ingredients according to the invention can also be applied to grains (coating), eitherby impregnating the seeds in a liquid formulation or by coating them with a solid formulation. Thecomposition can also be applied to the planting site when the propagation material is being planted,e.g., to the seed furrow during sowing. The invention relates also to such methods of treating plantpropagation material and to the plant propagation material so treated.Furthermore, the compounds according to present invention can be used for controlling fungi inrelated areas, for example in the protection of technical materials, including wood and wood relatedtechnical products, in food storage, in hygiene management.In addition, the invention could be used to protect non-living materials from fungal attack, e.g.,lumber, wall boards and paint.The compounds of formula (I) may be, for example, effective against fungi and fungal vectors ofdisease as well as phytopathogenic bacteria) and viruses. These fungi and fungal vectors of disease aswell as phytopathogenic bacteria and viruses are for example:Absidia corymbifera, Alternaria spp, Aphanomyces spp, Ascochyta spp, Aspergillus spp. includingA. flavus, A. fumigatus, A. nidulans, A. niger, A. terrus, Aureobasidium spp. including A. pullulans,Blastomyces dermatitidis, Blumeria graminis, Bremia lactucae, Botryosphaeria spp. including B.dothidea, B. obtusa, Botrytis spp. inclusing B. cinerea, Candida spp. including C. albicans, C. glabrata,C. krusei, C. lusitaniae, C. parapsilosis, C. tropicalis, Cephaloascus fragrans, Ceratocystis spp,Cercospora spp. including C. arachidicola, Cercosporidium personatum, Cladosporium spp, Clavicepspurpurea, Coccidioides immitis, Cochliobolus spp, Colletotrichum spp. including C. musae,Cryptococcus neoformans, Diaporthe spp, Didymella spp, Drechslera spp, Elsinoe spp,Epidermophyton spp, Erwinia amylovora, Erysiphe spp. including E. cichoracearum, Eutypa lata,Fusarium spp. including F. culmorum, F. graminearum, F. langsethiae, F. moniliforme, F. oxysporum,F. proliferatum, F. subglutinans, F. solani, Gaeumannomyces graminis, Gibberella fujikuroi, Gloeodespomigena, Gloeasporium musarum, Glomerella cingulate, Guignardia bidwellii, Gymnosporangiumjuniperi-virginianae, Helminthosporium spp, Hemileia spp, Histoplasma spp. including H. capsulatum,Laetisaria fuciformis, Leptographium lindbergi, Leveillula taurica, Lophodermium seditiosum,Microdochium nivale, Microsporum spp, Monilinia spp, Mucor spp, Mycosphaerella spp. including M.graminicola, M. pomi, Oncobasidium theobromaeon, Ophiostoma piceae, Paracoccidioides spp.Penicillium spp. including P. digitatum, P. italicum, Petriellidium spp, Peronosclerospora spp. IncludingP. maydis, P. philippinensis and P. sorghi, Peronospora spp, Phaeosphaeria nodorum, Phakopsorapachyrhizi, Phellinus igniarus, Phialophora spp, Phoma spp, Phomopsis viticola, Phytophthora spp.including P. infestans, Plasmopara spp. including P. halstedii, P. viticola, Pleospora spp., Podosphaeraspp. including P. leucotricha, Polymyxa graminis, Polymyxa betae, Pseudocercosporellaherpotrichoides, Pseudomonas spp, Pseudoperonospora spp. including P. cubensis, P. humuli,Pseudopeziza tracheiphila, Puccinia Spp. including P. hordei, P. recondita, P. striiformis, P. triticina,Pyrenopeziza spp, Pyrenophora spp, Pyricularia spp. including P. oryzae, Pythium spp. including P.ultimum, Ramularia spp, Rhizoctonia spp, Rhizomucor pusillus, Rhizopus arrhizus, Rhynchosporiumspp, Scedasporium spp. including S. apiospermum and S. prolificans, Schizothyrium pomi,Sclerotinia spp, Sclerotium spp, Septoria spp, including S. nodorum, S. tritici, Sphaerotheca macularis,Sphaerotheca fusca (Sphaerotheca fuliginea), Sporothorix spp, Stagonospara nodorum, Stemphyliumspp., Stereum hirsutum, Thanatephorus cucumeris, Thielaviopsis basicola, Tilletia spp, Trichodermaspp., including T. harzianum, T. pseudokoningii, T. viride, Trichophyton spp, Typhula spp, Uncinulanecator, Urocystis spp, Ustilago spp, Venturia spp. including V. inaequalis, Verticillium spp, andXanthomonas spp.Within the scope of present invention, target crops and / or useful plants to be protected typicallycomprise perennial and annual crops, such as berry plants for example blackberries, blueberries,cranberries, raspberries and strawberries; cereals for example barley, maize (corn), millet, oats, rice,rye, sorghum triticale and wheat; fibre plants for example cotton, flax, hemp, jute and sisal; field cropsfor example sugar and fodder beet, coffee, hops, mustard, oilseed rape (canola), poppy, sugar cane,sunflower, tea and tobacco; fruit trees for example apple, apricot, avocado, banana, cherry, citrus,nectarine, peach, pear and plum; grasses for example Bermuda grass, bluegrass, bentgrass, centipedegrass, fescue, ryegrass, St. Augustine grass and Zoysia grass; herbs such as basil, borage, chives,coriander, lavender, lovage, mint, oregang, parsley, rosemary, sage and thyme; legumes for examplebeans, lentils, peas and soya beans; nuts for example almond, cashew, ground nut, hazelnut, peanut,pecan, pistachio and walnut; palms for example oil palm; ornamentals for example flowers, shrubs andtrees; other trees, for example cacao, coconut, olive and rubber; vegetables for example asparagus,aubergine, broccoli, cabbage, carrot, cucumber, garlic, lettuce, marrow, melon, okra, onion, pepper,potato, pumpkin, rhubarb, spinach and tomato; and vines for example grapes.The term "useful plants" is to be understood as including also useful plants that have beenrendered tolerant to herbicides like bromoxynil or classes of herbicides (such as, for example, HPPDinhibitors, ALS inhibitors, for example primisulfuron, prosulfuron and trifloxysulfuron, EPSPS (5-enol-pyrovyl-shikimate-3-phosphate-synthase) inhibitors, GS (glutamine synthetase) inhibitors or PPO(protoporphyrinogen-oxidase) inhibitors) as a result of conventional methods of breeding or geneticengineering. An example of a crop that has been rendered tolerant to imidazolinones, e.g. imazamox,by conventional methods of breeding (mutagenesis) is Clearfield summer rape (Canola). Examples ofcrops that have been rendered tolerant to herbicides or classes of herbicides by genetic engineeringmethods include glyphosate- and glufosinate-resistant maize varieties commercially available under thetrade names RoundupReady, Herculex I and LibertyLink.The term "useful plants" is to be understood as including also useful plants which have been sotransformed by the use of recombinant DNA techniques that they are capable of synthesising one ormare selectively acting toxins, such as are known, for example, from toxin-producing bacteria, especiallythose of the genus Bacillus.Examples of such plants are: YieldGard (maize variety that expresses a Cry(lA)(b) toxin);YieldGard Rootworm (maize variety that expresses a CryllIB(b1) toxin); YieldGard Plus (maizevariety that expresses a Cry(IA)(b) and a CryllIB(b1) toxin); Starlink (maize variety that expresses aCry9(c) toxin); Herculex I (maize variety that expresses a CrylF(a2) toxin and the enzymephasphinothricine N-acetyltransferase (PAT) to achieve tolerance to the herbicide glufosinateammonium); NuCOTN 33B (cotton variety that expresses a Cry(IA)(c) toxin); Bollgard I (cottonvariety that expresses a Cry(IA)(c) toxin); Bollgard [I (cotton variety that expresses a Cry(IA)(c) and aCryl(IA)(b) toxin); VIPCOT (cotton variety that expresses a VIP toxin); NewLeaf (potato variety thatexpresses a Cryll(lA) toxin); NatureGard Agrisure GT Advantage (GA21 glyphosate-tolerant trait),Agrisure CB Advantage (Bt11 corn borer (CB) trait), Agrisure RW (corn rootworm trait) and Protecta.The term "crops" is to be understood as including also crop plants which have been sotransformed by the use of recombinant DNA techniques that they are capable of synthesising one ormore selectively acting toxins, such as are known, for example, from toxin-producing bacteria, especiallythose of the genus Bacillus.Toxins that can be expressed by such transgenic plants include, for example, insecticidalproteins from Bacillus cereus or Bacillus popilliae; or insecticidal proteins from Bacillus thuringiensis,such as 3-endotoxins, e.g. Cry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1 or Cry9C, orvegetative insecticidal proteins (Vip), e.g. Vip1, Vip2, Vip3 or Vip3A; or insecticidal proteins of bacteriacolonising nematodes, for example Photorhabdus spp. or Xenorhabdus spp., such as Photorhabdusluminescens, Xenorhabdus nematophilus; toxins produced by animals, such as scorpion toxins,arachnid toxins, wasp toxins and other insect-specific neurotoxins; toxins produced by fungi, such asStreptomycetes toxins, plant lectins, such as pea lectins, barley lectins or snowdrop lectins; agglutinins;proteinase inhibitors, such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin, papaininhibitors; ribosome-inactivating proteins (RIP), such as ricin, maize-RIP, abrin, luffin, saporin or bryodin;steroid metabolism enzymes, such as 3-hydroxysteroidoxidase, ecdysteroid-UDP-glycosyl-transferase,cholesterol oxidases, ecdysone inhibitors, HMG-COA-reductase, ion channel blockers, such as blockersof sodium or calcium channels, juvenile hormone esterase, diuretic hormone receptors, stilbenesynthase, bibenzyl synthase, chitinases and glucanases.In the context of the present invention there are to be understood by 3-endotoxins, for exampleCry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1 or Cry9C, or vegetative insecticidal proteins(Vip), for example Vip1, Vip2, Vip3 or Vip3A, expressly also hybrid toxins, truncated toxins and modifiedtoxins. Hybrid toxins are produced recombinantly by a new combination of different domains of thoseproteins (see, for example, WO 02 / 15701). Truncated toxins, for example a truncated Cry1Ab, areknown. In the case of modified toxins, one or more amino acids of the naturally occurring toxin arereplaced. In such amino acid replacements, preferably non-naturally present protease recognitionsequences are inserted into the toxin, such as, for example, in the case of Cry3A055, a cathepsin-G-recognition sequence is inserted into a Cry3A toxin (see WO 03 / 018810).Examples of such toxins or transgenic plants capable of synthesising such toxins are disclosed,for example, in EP-A-0 374 753, WO 93 / 07278, WO 95 / 34656, EP-A-0 427 529, EP-A-451 878 and WO03 / 052073. The processes for the preparation of such transgenic plants are generally known to theperson skilled in the art and are described, for example, in the publications mentioned above. Cryl-typedeoxyribonucleic acids and their preparation are known, for example, from WO 95 / 34656, EP-A-0 367474, EP-A-0 401 979 and WO 90 / 13651.The toxin contained in the transgenic plants imparts to the plants tolerance to harmful insects.Such insects can occur in any taxonomic group of insects, but are especially commonly found in thebeetles (Coleoptera), two-winged insects (Diptera) and butterflies (Lepidoptera).Transgenic plants containing one or more genes that code for an insecticidal resistance andexpress one or more toxins are known and some of them are commercially available. Examples of suchplants are: YieldGard (maize variety that expresses a Cry1Ab toxin); YieldGard Rootworm (maizevariety that expresses a Cry3Bb1 toxin); YieldGard Plus (maize variety that expresses a Cry1Ab anda Cry3Bb1 toxin); Starlink (maize variety that expresses a Cry9C toxin); Herculex I (maize varietythat expresses a Cry1Fa2 toxin and the enzyme phosphinothricine N-acetyltransferase (PAT) to achievetolerance to the herbicide glufosinate ammonium); NuCOTN 33B (cotton variety that expresses aCry1Ac toxin); Bollgard I (cotton variety that expresses a Cry1Ac toxin); Bollgard |I (cotton varietythat expresses a CrylAc and a Cry2Ab toxin); VipCot (cotton variety that expresses a Vip3A and aCry1Ab toxin); NewlLeaf (potato variety that expresses a Cry3A toxin); NatureGard, Agrisure GTAdvantage (GAZ21 glyphosate-tolerant trait), Agrisure CB Advantage (Bt11 corn borer (CB) trait) andProtecta.Further examples of such transgenic crops are:1. Bt11 Maize from Syngenta Seeds SAS, Chemin de I'Hobit 27, F-31 790 St. Sauveur, France,registration number C / FR / 96 / 05 / 10. Genetically modified Zea mays which has been rendered resistantto attack by the European corn borer (Ostrinia nubilalis and Sesamia nonagrioides) by transgenicexpression of a truncated Cry1Ab toxin. Bt11 maize also transgenically expresses the enzyme PAT toachieve tolerance to the herbicide glufosinate ammonium.2. Bt176 Maize from Syngenta Seeds SAS, Chemin de I'Hobit 27, F-31 790 St. Sauveur, France,registration number C / FR / 96 / 05 / 10. Genetically modified Zea mays which has been rendered resistantto attack by the European corn borer (Ostrinia nubilalis and Sesamia nonagricides) by transgenicexpression of a Cry1Ab toxin. Bt176 maize also transgenically expresses the enzyme PAT to achievetolerance to the herbicide glufosinate ammonium.3. MIR604 Maize from Syngenta Seeds SAS, Chemin de I'Hobit 27, F-31 790 St. Sauveur, France,registration number C / FR / 96 / 05 / 10. Maize which has been rendered insect-resistant by transgenicexpression of a modified Cry3A toxin. This toxin is Cry3A055 modified by insertion of a cathepsin-G-protease recognition sequence. The preparation of such transgenic maize plants is described in WO03 / 018810.4. MON 863 Maize from Monsanto Europe S.A. 270-272 Avenue de Tervuren, B-1150 Brussels,Belgium, registration number C / DE / 02 / 9. MON 863 expresses a Cry3Bb1 toxin and has resistance tocertain Coleoptera insects.5. IPC 531 Cotton from Monsanto Europe S.A. 270-272 Avenue de Tervuren, B-1150 Brussels,Belgium, registration number C / ES / 96 / 02.6. 1507 Maize from Pioneer Overseas Corporation, Avenue Tedesco, 7 B-1160 Brussels, Belgium,registration number C / NL / 00 / 10. Genetically modified maize for the expression of the protein Cry1F forachieving resistance to certain Lepidoptera insects and of the PAT protein for achieving tolerance to theherbicide glufosinate ammonium.7. NK603 x MON 810 Maize from Monsanto Europe S.A. 270-272 Avenue de Tervuren, B-1150Brussels, Belgium, registration number C / GB / 02 / M3 / 03. Consists of conventionally bred hybrid maizevarieties by crossing the genetically modified varieties NK603 and MON 810. NK603 x MON 810 Maizetransgenically expresses the protein CP4 EPSPS, obtained from Agrobacterium sp. strain CP4, whichimparts tolerance to the herbicide Roundup (contains glyphosate), and also a Cry1Ab toxin obtainedfrom Bacillus thuringiensis subsp. kurstaki which brings about tolerance to certain Lepidoptera, includethe European corn borer.Additionally, to date, no cross-resistance has been observed between the compounds of Formula(I) (including any one of compounds described in Table 2 (below)) and any fungicidal solutions used tocontrol phytopathogenic fungi such as Absidia corymbifera, Alternaria spp, Aphanomyces spp,Ascochyta spp, Aspergillus spp. including A. flavus, A. fumigatus, A. nidulans, A. niger, A. terrus,Aureobasidium spp. including A. pullulans, Blastomyces dermatitidis, Blumeria graminis, Bremialactucae, Botryosphaeria spp. including B. dothidea, B. obtusa, Botrytis spp. inclusing B. cinerea,Candida spp. including C. albicans, C. glabrata, C. krusei, C. lusitaniae, C. parapsilosis, C. tropicalis,Cephaloascus fragrans, Ceratocystis spp, Cercospora spp. including C. arachidicola, Cercosporidiumpersonatum, Cladosporium spp, Claviceps purpurea, Coccidioides immitis, Cochliobolus spp,Colletotrichum spp. including C. musae, Cryptococcus neoformans, Diaporthe spp, Didymella spp,Drechslera spp, Elsinoe spp, Epidermophyton spp, Erwinia amylovora, Erysiphe spp. including E.cichoracearum, Eutypa lata, Fusarium spp. including F. culmorum, F. graminearum, F. langsethiae, F.moniliforme, F. oxysporum, F. profiferatum, F. subglufinans, F. solani, Gaeumannomyces graminis,Gibberella fujikuroi, Gloeodes pomigena, Gloeosporium musarum, Glomerella cingulate, Guignardiabidwellii, Gymnosporangium juniperi-virginianae, Helminthosporium spp, Hemileia spp, Histoplasmaspp. including H. capsulatum, Laetisaria fuciformis, Leptographium lindbergi, Leveillula taurica,Lophodermium seditiosum, Microdochium nivale, Microsporum spp, Monilinia spp, Mucor spp,Mycosphaerella spp. including M. graminicola, M. pomi, Oncobasidium theobromaeon, Ophiostomapiceae, Paracoccidioides spp, Penicillium spp. including P. digitatum, P. italicum, Petriellidium spp,Peronosclerospora spp. Including P. maydis, P. philippinensis and P. sorghi, Peronospora spp,Phaeosphaeria nodorum, Phakopsora pachyrhizi, Phelflinus igniarus, Phialophora spp, Phoma spp,Phomopsis viticola, Phytophthora spp. including P. infestans, Plasmopara spp. including P. halstedii, P.viticola, FPleospora spp., Podosphaera spp. including P. leucotricha, Polymyxa graminis, Polymyxabetae, Pseudocercosporella herpotrichoides, Pseudomonas spp, Pseudoperonospora spp. including P.cubensis, P. humuli, Pseudopeziza tracheiphila, Puccinia Spp. including P. hordei, P. recondita, P.striiformis, P. triticina, Pyrenopeziza spp, Pyrenophora spp, Pyricularia spp. including P. oryzae, Pythiumspp. including P. ultimum, Ramularia spp, Rhizoctonia spp, Rhizomucor pusilius, Rhizopus arrhizus,Rhynchosporium spp, Scedosporium spp. including S. apiospermum and S. prolificans, Schizothyriumpom, Sclerotinia spp, Sclerotium spp, Septoria spp, including S. nodorum, S. tritici, Sphaerothecamacularis, Sphaerotheca fusca (Sphaerotheca fuliginea), Sporothorix spp, Stagonospora nodorum,Stemphylium spp., Stereum hirsutum, Thanatephorus cucumeris, Thielaviopsis basicola, Tilletia spp,Trichoderma spp., including T. harzianum, T. pseudokoningii, T. viride, Trichophyton spp, Typhula spp,Uncinula necator, Urocystis spp, Ustilago spp, Venturia spp. including V. inaequalis, Verticillium spp,and Xanthomonas Spp., in particular, Zymoseptoria tritici, Puccinia recondita, Pucciniastriiformis, Erysiphe graminis, Uncinula necator, Sphaerotheca fuliginea, Leveillula taurica, Phakopsorapachyrhizi, Pyricularia oryzae, Alternaria solani, Alternaria alternata, Mycosphaerella fijiensis,Colletotrichum lagenarium, Didymella bryoniae, Ascochyta pisii, Verticillium dahliae, Pyrenophora teres,Cercospora beticola, Ramularia colfo-cygni, Botrytis cinerea, Sclerotinia sclerotiorum, Monilinia laxa,Monographaelia nivalis and Venturia inaequalis.Indeed, fungicidal-resistant strains in any of the species as outlined above have been reported inthe scientific literature, with strains resistant to one or more fungicides from at least one of the followingfungicidal mode of action classes: quinone-outside-inhibitors (Qol), quinone-inside-inhibitors (Qil),succinate dehydrogenase inhibitors (SDHI) and sterol demethylation-inhibitors (DMI). Such fungicidal-resistant strains may contain:» A mutation in the mitochondrial cytochrome b gene conferring resistance to Qo inhibitors, whereinthe mutation is G143A, F129L or G137R. See for example: Gisi et al., Pest Manag Sci 56, 833-841,(2000), Lucas, Pestic Outlook 14(6), 268-70 (2003), Fraaije et al., Phytopathol 95(8), 933-41 (2005),Sierotzki et al., Pest Manag Sci 63(3), 225-233 (2007), Semar et al, Journal of Plant Diseases andProtection (3), 117-119 (2007); and Pasche et al., Crop Protection 27(3-5), 427-435 (2008).» A mutation in the mitochondrial cytochrome b gene conferring resistance to Qi inhibitors, wherein themutation is G37A / C / D / S / V. See for example: Meunier et al., Pest Manag Sci 2019; 75: 2107-2114.» A mutation in the genes encoding the SdhB,C,D subunits conferring resistance to SDHI inhibitorswherein the mutation is in the following major pathogens:o Botrytis cinerea: B-P225H / L / T / YIF, B-N230I, B-H272L / Y / R, C-P80H / L, C-N87S ;o Alternaria solani: B-H278R / Y, C-H134R / Q, D-D123E, D-H133R and C-H134R;o Zymoseptoria tritici: sdhB: N225T, N225I, R265P, T268I, T268A. In sdhC: T79N, T79I,W80S, WB0A, AB4F, N8BS, N86A, P127A, R151M / S / T / G, R151S, R151T, H152R / Y, V166M,T168R. In sdhD: 150F, M114V, D129G, T20P+K186R;o Pyrenophora teres: In sdhB: S66P, N235l, H277Y. In sdhC: K49E, R64K, N75S, G79R,H134R, S135R. In sdhD: D124E, H134R, G138V, D145G;o Ramularia collo-cyagni: In sdhB: N224T, T2671. In sdhC: N87S, G91R, H146R / L, G171D,H153R;o Phakopsora pachyrhizi: C-186F;o Sclerotinia sclerotiorum: In sdhB: H273Y. In sdhC: G91R, H146R. In sdhD: T108K, H132R,G150R.Major source of information is www .frac.info, Sierotzki and Scalliet Phytopathology (2013) 103(9): 880-887 and Simdes et al., J Plant Dis Prof (2018) 125: 21-2.s A mutation or combination of mutations in the CYP31 gene conferring resistance to DMI inhibitorswherein the mutations are: L50S, D134G, V136A / C, Y137F, S188N, A379G, I1381V, deletion 459-480, Y461H / S, N513K, 8524T. Major source of information is www.frac.info, Cools et al., Plant Pathol(2013) 62: 38-42 and Schmitz HK et al., Pest Manag Sci (2014) 70: 378-388.Thus, in a preferred embodiment, the compounds of Formula (I) (including any one of compoundsdescribed in Table 2 (below)), or fungicidal compositions according to the present invention comprisinga compound of Formula (I), are used to control fungal strains which are resistant to one or morefungicides from any of the following fungicidal MoA classes: quinone-outside-inhibitors (Qol), quinone-inside-inhibitors (Qil), succinate dehydrogenase inhibitors (SDHI) and sterol demethylation-inhibitors(DMI).The term "locus" as used herein means fields in or on which plants are growing, or where seedsof cultivated plants are sown, or where seed will be placed into the soil. It includes soil, seeds, andseedlings, as well as established vegetation.The term "plants" refers to all physical parts of a plant, including seeds, seedlings, saplings, roots,tubers, stems, stalks, foliage, and fruits.The term "plant propagation material" is understood to denote generative parts of the plant, suchas seeds, which can be used for the multiplication of the latter, and vegetative material, such as cuttingsor tubers, for example potatoes. There may be mentioned for example seeds (in the strict sense), roots,fruits, tubers, bulbs, rhizomes and parts of plants. Germinated plants and young plants which are to betransplanted after germination or after emergence from the soil, may also be mentioned. These youngplants may be protected before transplantation by a total or partial treatment by immersion. Preferably"plant propagation material" is understood to denote seeds.Pesticidal agents referred to herein using their common name are known, for example, from "ThePesticide Manual", 15th Ed., British Crop Protection Council 2009.The compounds of formula (I) may be used in unmodified form or, preferably, together with theadjuvants conventionally employed in the art of formulation. To this end, they may be convenientlyformulated in known manner to emulsifiable concentrates, coatable pastes, directly sprayable ordilutable solutions or suspensions, dilute emulsions, wettable powders, soluble powders, dusts,granulates, and also encapsulations e.g. in polymeric substances. As with the type of the compositions,the methods of application, such as spraying, atomising, dusting, scattering, coating or pouring, arechosen in accordance with the intended objectives and the prevailing circumstances. The compositionsmay also contain further adjuvants such as stabilizers, antifoams, viscosity regulators, binders ortackifiers as well as fertilizers, micronutrient donors or other formulations for obtaining special effects.Suitable carriers and adjuvants, e.g., for agricultural use, can be solid or liquid and are substancesuseful in formulation technology, e.g. natural ar regenerated mineral substances, solvents, dispersants,wetting agents, tackifiers, thickeners, binders or fertilizers. Such carriers are for example described inWO 97 / 33890.The compounds of formula (I) are normally used in the form of compositions and can be appliedto the crop area or plant to be treated, simultaneously or in succession with further compounds. Thesefurther compounds can be, e.g, fertilizers or micronutrient donors or other preparations, which influencethe growth of plants. They can also be selective herbicides or non-selective herbicides as well asinsecticides, fungicides, bactericides, nematicides, molluscicides ar mixtures of several of thesepreparations, if desired together with further carriers, surfactants or application promoting adjuvantscustomarily employed in the art of formulation.The compounds of formula (I) may be used in the form of (fungicidal) compositions for controllingor protecting against phytopathogenic microorganisms, comprising as active ingredient at least onecompound of formula (I) or of at least one preferred individual compound as above-defined, in free formor in agrochemically usable salt form, and at least one of the above-mentioned adjuvants.The invention provides a composition, preferably a fungicidal composition, comprising at least onecompound formula (I) an agriculturally acceptable carrier and optionally an adjuvant. An agriculturalacceptable carrier is for example a carrier that is suitable for agricultural use. Agricultural carriers arewell known in the art. Preferably, said composition may comprise at least one or more pesticidally activecompounds, for example an additional fungicidal active ingredient in addition to the compound of formula0.The compound of formula (I) may be the sole active ingredient of a composition or it may beadmixed with one or more additional active ingredients such as a pesticide, fungicide, synergist,herbicide or plant growth regulator where appropriate. An additional active ingredient may, in somecases, result in unexpected synergistic activities.Examples of suitable additional active ingredients include the following acycloamino acidfungicides, aliphatic nitrogen fungicides, amide fungicides, anilide fungicides, antibiotic fungicides,aromatic fungicides, arsenical fungicides, aryl phenyl ketone fungicides, benzamide fungicides,benzanilide fungicides, benzimidazole fungicides, benzothiazole fungicides, botanical fungicides,bridged diphenyl fungicides, carbamate fungicides, carbanilate fungicides, conazole fungicides, copperfungicides, dicarboximide fungicides, dinitrophenol fungicides, dithiocarbamate fungicides, dithiolanefungicides, furamide fungicides, furanilide fungicides, hydrazide fungicides, imidazole fungicides,mercury fungicides, morpholine fungicides, organophosphorous fungicides, organotin fungicides,oxathiin fungicides, oxazole fungicides, phenylsulfamide fungicides, polysulfide fungicides, pyrazolefungicides, pyridine fungicides, pyrimidine fungicides, pyrrole fungicides, quaternary ammoniumfungicides, quinoline fungicides, quinone fungicides, quinoxaline fungicides, strobilurin fungicides,sulfonanilide fungicides, thiadiazole fungicides, thiazole fungicides, thiazolidine fungicides,thiocarbamate fungicides, thiophene fungicides, triazine fungicides, triazole fungicides,triazolopyrimidine fungicides, urea fungicides, valinamide fungicides, and zinc fungicides.Examples of suitable additional active ingredients also include the following: petroleum cils, 1,1-bis(4-chlorophenyl)-2-ethoxyesthanol, 2,4-dichlorophenyl benzenesulfonate, 2-fluoro-N-methyl-N-1-naphthylacetamide, 4-chlorophenyl phenyl sulfone, acetoprole, aldoxycarb, amidithion, amidothioate,amiton, amiton hydrogen oxalate, amitraz, aramite, arsenous oxide, azobenzene, azothoate, benomyl,benoxafos, benzyl benzoate, bixafen, brofenvalerate, bromocyclen, bromophos, bromopropylate,buprofezin, butocarboxim, butoxycarboxim, butylpyridaben, calcium polysulfide, camphechlor,carbanolate, carbophenothion, cymiazole, chinomethionat, chlorbenside, chlordimeform, chlordimeformhydrochloride, chlorfenethol, chlorfenson, chlorfensulfide, chlorobenzilate, chloromebuform,chloromethiuron, chloropropylate, chlorthiophos, cinerin I, cinerin Il, cinerins, closantel, coumaphos,crotamiton, crotaxyphos, cufraneb, cyanthoate, DCPM, DDT, demephion, demephion-O, demephion-S,demeton-methyl, demeton-O, demeton-O-methyl, demeton-S, demeton-S-methyl, demeton-S-methylsulfon, dichlofluanid, dichlorvos, dicliphos, dienochlor, dimefox, dinex, dinex-diclexine, dinocap-4, dinocap-6, dinocton, dinopenton, dinosulfon, dinoterbon, dioxathion, diphenyl sulfone, disulfiram,DNOC, dofenapyn, doramectin, endothion, eprinomectin, ethoate-methyl, etrimfos, fenazaflor,fenbutatin oxide, fenothiocarb, fenpyrad, fenpyroximate, fenpyrazamine, fenson, fentrifanil,flubenzimine, flucycloxuron, fluenetil, fluorbenside, FMC 1137, formetanate, formetanate hydrochloride,formparanate, gamma-HCH, glyodin, halfenprox, hexadecyl cyclopropanecarboxylate, isocarbophos,jasmolin I, jasmolin Il, jodfenphos, lindane, malonoben, mecarbam, mephosfolan, mesulfen,methacrifos, methyl bromide, metolcarb, mexacarbate, milbemycin oxime, mipafox, monocrotophos,morphothion, moxidectin, naled, 4-chloro-2-(2-chloro-2-methyl-propyl)-5-[(6-iodo-3-pyridyl)methoxy]pyridazin-3-one, nifluridide, nikkomycins, nitrilacarb, nitrilacarb 1:1 zinc chloridecomplex, omethoate, oxydeprofos, oxydisulfoton, pp'-DDT, parathion, permethrin, phenkapton,phasalone, phosfolan, phosphamidan, polychloroterpenes, polynactins, proclonol, promacyl, propoxur,prothidathion, prothoate, pyrethrin 1, pyrethrin Il, pyrethrins, pyridaphenthion, pyrimitate, quinalphos,quintiofos, R-1492, phosglycin, rotenone, schradan, sebufos, selamectin, sophamide, 3SI-121, sulfiram,sulfluramid, sulfotep, sulfur, diflovidazin, tau-fluvalinate, TEPP, terbam, tetradifon, tetrasul, thiafenox,thiocarboxime, thiofanox, thiometon, thioquinox, thuringiensin, triamiphos, triarathene, triazophos,triazuron, trifenofos, trinactin, vamidothion, vaniliprole, bethoxazin, copper dioctanoate, copper sulfate,cybutryne, dichlone, dichlorophen, endothal, fentin, hydrated lime, nabam, quinoclamine, quinonamid,simazine, triphenyltin acetate, triphenyltin hydroxide, crufomate, piperazine, thiophanate, chloralose,fenthion, pyridin-4-amine, strychnine, 1-hydroxy-1H-pyridine-2-thione, 4-(quinoxalin-2-ylamino)benzenesulfonamide, 8-hydroxyquinoline sulfate, bronopol, copper hydroxide, cresal,dipyrithione, dodicin, fenaminosulf, formaldehyde, hydrargaphen, kasugamycin, kasugamycinhydrochloride hydrate, nickel bis(dimethyldithiocarbamate), nitrapyrin, octhilinone, oxolinic acid,oxytetracycline, potassium hydroxyquinoline sulfate, probenazole, streptomycin, streptomycinsesquisulfate, tecloftalam, thiomersal, Adoxophyes orana GV, Agrobacterium radiobacter, Amblyseiusspp., Anagrapha falcifera NPV, Anagrus atomus, Aphelinus abdominalis, Aphidius colemani,Aphidoletes aphidimyza, Autographa californica NPV, Bacillus sphaericus Neide, Beauveria brongniartii,Chrysoperla carnea, Cryptolaemus montrouzieri, Cydia pomonella GV, Dacnusa sibirica, Diglyphusisaea, Encarsia formosa, Eretmocerus eremicus, Heterorhabditis bacteriophora and H. megidis,Hippodamia convergens, Leptomastix dactylopii, Macrolophus caliginosus, Mamestra brassicae NPV,Metaphycus helvolus, Metarhizium anisopliae var. acridum, Metarhizium anisopliae var. anisopliae,Neodiprion sertifer NPV and N. lecontei NPV, Orius spp., Paecilomyces fumosoroseus, Phytoseiuluspersimilis, Steinemema bibionis, Steinernema carpocapsae, Steinernema feltiae, Steinernema glaseri,Steinernema riobrave, Steinernema riobravis, Steinernema scapterisci, Steinernema spp..Trichogramma spp., Typhlodromus occidentalis, Verticillium lecanii, apholate, bisazir, busulfan, dimatif,hemel, hempa, metepa, methiotepa, methyl apholate, morzid, penfluron, tepa, thichempa, thiotepa,tretamine, uredepa, (E)-dec-5-en-1-yl acetate with (E)-dec-5-en-1-ol, (E)-tridec-4-en-1-yl acetate, (E)-6-methylhept-2-en-4-ol, (E,Z)-tetradeca-4,10-dien-1-yl acetate, (Z)-dodec-7-en-1-yl acetate, (Z)-hexadec-11-enal, (Z)-hexadec-11-en-1-yl acetate, (Z)-hexadec-13-en-11-yn-1-yl acetate, (Z)-icos-13-en-10-one,(2)-tetradec-7-en-1-al, (Z)-tetradec-9-en-1-ol, (Z)-letradec-9-en-1-yl acetate, (7E,92)-dodeca-7,9-dien-1-yl acetate, (9Z,11E)-tetradeca-9,11-dien-1-yl acetate, (9Z,12E)-tetradeca-9,12-dien-1-yl acetate, 14-methyloctadec-1-ene, 4-methylnonan-5-ol with 4-methylnonan-5-one, alpha-multistriatin, brevicomin,codlelure, codlemone, cuelure, disparlure, dodec-8-en-1-yl acetate, dodec-9-en-1-yl acetate, dodeca-8,10-dien-1-yl acetate, dominicalure, ethyl 4-methyloctanoate, eugenol, frontalin, grandlure, grandlure |,grandlure Il, grandlure Ill, grandlure 1V, hexalure, ipsdienol, ipsenol, japonilure, lineatin, litlure, looplure,medlure, megatomoic acid, methyl eugenol, muscalure, octadeca-2,13-dien-1-yl acetate, octadeca-3,13-dien-1-yl acetate, orfralure, oryctalure, ostramone, siglure, sordidin, sulcatol, tetradec-11-en-1-ylacetate, trimedlure, trimedlure A, trimedlure Ba, trimedlure Bz, trimedlure C, trunc-call, 2-(octylthio)-ethanol, butopyronoxyl, butoxy(polypropylene glycol), dibutyl adipate, dibutyl phthalate, dibutylsuccinate, diethyltoluamide, dimethyl carbate, dimethyl phthalate, ethyl hexanediol, hexamide,methoquin-butyl, methylneodecanamide, oxamate, picaridin, 1-dichloro-1-nitroethane, 1,1-dichloro-2,2-bis(4-ethylphenyl)ethane, 1,2-dichloropropane with 1.3-dichloropropene, 1-bromo-2-chloroethane,2,2,2-trichloro-1-(3,4-dichlorophenyl)ethyl acetate, 2,2-dichlorovinyl 2-ethylsulfinylethyl methylphosphate, 2-(1,3-dithiolan-2-yl)phenyl dimethylcarbamate, 2-(2-butoxyethoxy)ethyl thiocyanate, 2-(4,5-dimethyl-1,3-dioxolan-2-ylyphenyl methylcarbamate, 2-(4-chloro-3,5-xylyloxy)ethanol, 2-chlorovinyldiethyl phosphate, 2-imidazolidone, 2-isovalerylindan-1,3-dione, 2-methyl(prop-2-ynyl)aminophenylmethylcarbamate, 2-thiocyanatoethyl laurate, 3-bromo-1-chloroprop-1-ene, 3-methyl-1-phenylpyrazol-5-yl dimethylcarbamate, 4-methyl(prop-2-ynyl)amino-3,5-xylyl methylcarbamate, 5,5-dimethyl-3-oxocyclohex-1-enyl dimethylcarbamate, acethion, acrylonitrile, aldrin, allosamidin, allyxycarb, alpha-ecdysone, aluminium phosphide, aminocarb, anabasine, athidathion, azamethiphos, Bacillusthuringiensis delta endotoxins, barium hexafluorosilicate, barium polysulfide, barthrin, Bayer 22 / 190,Bayer 22408, beta-cyfluthrin, beta-cypermethrin, bioethanomethrin, biopermethrin, bis(2-chloroethyl)ether, borax, bromfenvinfos, bromo-DDT, bufencarb, butacarb, butathiofos, butonate, calcium arsenate,calcium cyanide, carbon disulfide, carbon tetrachloride, cartap hydrochloride, cevadine, chlorbicyclen,chlordane, chlordecone, chloroform, chloropicrin, chlorphoxim, chlorprazophos, cis-resmethrin,cismethrin, clocythrin, copper acetoarsenite, copper arsenate, copper oleate, coumithoate, cryolite, CS708, cyanafenphos, cyanophos, cyclethrin, cythicate, d-tetramethrin, DAEP, dazomet, decarbofuran,diamidafos, dicapthon, dichlofenthion, dicresyl, dicyclanil, dieldrin, diethyl 5-methylpyrazol-3-ylphosphate, dilor, dimefluthrin, dimetan, dimethrin, dimethylvinphos, dimetilan, dinoprop, dinosam,dinoseb, diofenalan, dioxabenzofos, dithicrofos, DSP, ecdysterone, El 1642, EMPC, EPBP, etaphos,ethiofencarb, ethyl formate, ethylene dibromide, ethylene dichloride, ethylene oxide, EXD, fenchlorphos,fenethacarb, fenitrothion, fenoxacrim, fenpirithrin, fensulfothion, fenthion-ethyl, flucofuron, fosmethilan,fospirate, fosthietan, furathiocarb, furethrin, guazatine, guazatine acetates, sodium tetrathiocarbonate,halfenprox, HCH, HEOD, heptachlor, heterophos, HHDN, hydrogen cyanide, hyquincarb, IPSP,isazofos, isobenzan, isodrin, isofenphos, isolane, isoprothiolane, isoxathion, juvenile hormone I, juvenilehormone Il, juvenile hormone lll, kelevan, kinoprene, lead arsenate, leptophos, lirimfos, lythidathion, m-cumenyl methylcarbamate, magnesium phosphide, mazidox, mecarphon, menazon, mercurouschloride, mesulfenfos, metam, metam-potassium, metam-sodium, methanesulfonyl fluoride,methocrotophos, methoprene, methothrin, methoxychlor, methyl isothiocyanate, methylchloroform,methylene chloride, metoxadiazone, mirex, naftalofos, naphthalene, NC-170, nicotine, nicotine sulfate,nithiazine, nornicotine, O-5-dichloro-4-iodophenyl O-ethyl ethylphosphaonothioate, O,O-diethyl O-4-methyl-2-oxo-2H-chromen-7-yl ~~ phosphorothioate, O,0-diethyl O-6-methyl-2-propylpyrimidin-4-ylphosphorothioate, ,0,0' O'-tetrapropyl dithiopyrophosphate, oleic acid, para-dichlorobenzene,parathion-methyl, pentachlorophenol, pentachlorophenyl laurate, PH 60-38, phenkapton, phosnichlor,phosphine, phoxim-methyl, pirimetaphos, polychlorodicyclopentadiene isomers, potassium arsenite,potassium thiocyanate, precocene |, precocene Il, precocene lll, primidophos, profluthrin, promecarb,prothiofos, pyrazophos, pyresmethrin, quassia, quinalphos-methyl, quinothion, rafoxanide, resmethrin,rotenone, kadethrin, ryania, ryanodine, sabadilla), schradan, sebufos, SI-0009, thiapronil, sodiumarsenite, sodium cyanide, sodium fluoride, sodium hexafluorosilicate, sodium pentachlorophenoxide,sodium selenate, sodium thiocyanate, sulcofuron, sulcofuron-sodium, sulfuryl fluoride, sulprofos, tar oils,tazimcarb, TDE, tebupirimfos, temephos, terallethrin, tetrachloroethane, thicrofos, thiocyclam,thiocyclam hydrogen oxalate, thionazin, thiosultap, thiosultap-sodium, tralomethrin, transpermethrin,triazamate, trichlormetaphos-3, trichloronat, trimethacarb, tolprocarb, triclopyricarb, triprene, veratridine,veratrine, XMC, zetamethrin, zinc phosphide, zolaprofos,and meperfluthrin, tetramethylfluthrin, bis(tributyltin) oxide, bromoacetamide, ferric phosphate,niclosamide-olamine, tributyltin oxide, pyrimorph, trifenmorph, 1,2-dibromo-3-chloropropane, 1,3-dichloropropene, 3,4-dichlorotetrahydrothiophene 1,1-dioxide, 3-(4-chlorophenyl)-5-methylrhodanine,5-methyl-6-thioxo-1,3,5-thiadiazinan-3-ylacetic acid, 6-isopentenylaminopurine, anisiflupurin, benclothiaz, cytokinins, DCIP, furfural, isamidofos, kinetin,Myrothecium verrucaria composition, tetrachlorothiophene, xylenols, zeatin, potassium ethylxanthate,acibenzolar, acibenzolar-S-methyl, Reynoutria sachalinensis extract, alpha-chlorohydrin, antu, bariumcarbonate, bisthiosemi, brodifacoum, bromadiolone, bromethalin, chlorophacinone, cholecalciferal,coumachlor, coumafuryl, coumatetralyl, crimidine, difenacoum, difethialone, diphacinone, ergocalciferal,flocoumafen, fluoroacetamide, flupropadine, flupropadine hydrochloride, norbormide, phosacetim,phosphorus, pindone, pyrinuron, scilliroside, sodium fluoroacetate, thallium sulfate, warfarin, 2-(2-butoxyethoxy)ethyl piperonylate, 5-(1,3-benzodioxol-5-yl)-3-hexylcyclohex-2-enone, farnesol withnerolidol, verbutin, MGK 264, piperonyl butoxide, piprotal, propyl isomer, S421, sesamex, sesasmolin,sulfoxide, anthraquinone, copper naphthenate, copper oxychloride, dicyclopentadiene, thiram, zincnaphthenate, ziram, imanin, ribavirin, chloreinconazide, mercuric oxide, thiophanate-methyl,azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole,fenbuconazole, fluquinconazole, flusilazole, flutriafol, furametpyr, hexaconazole, imazalil, imibencon-azole, ipconazole, metconazole, myclobutanil, paclobutrazole, pefurazoate, penconazole,prothioconazole, pyrifenox, prochloraz, propiconazole, pyrisoxazole, simeconazole, tebuconazole,tetraconazole, triadimefon, triadimenol, triflumizole, triticonazole, ancymidol, fenarimol, nuarimal,bupirimate, dimethirimol, ethirimol, dodemoarph, fenpropidin, fenpropimorph, spiroxamine, tridemorph,cyprodinil, mepanipyrim, pyrimethanil, fenpiclonil, fludioxonil, benalaxyl, furalaxyl, metalaxyl.R-metalaxyl, ofurace, oxadixyl, carbendazim, debacarb, fuberidazole, thiabendazole, chlozolinate,dichlozoline, myclozoline, procymidone, vinclozoline, boscalid, carboxin, fenfuram, flutolanil, mepronil,oxycarboxin, penthiopyrad, thifluzamide, dodine, iminoctadine, azoxystrobin, dimoxystrobin,enestroburin, fenaminstrobin, flufenoxystrobin, fluoxastrobin, kresoxim-methyl, metominostrobin,trifloxystrobin, orysastrobin, picoxystrobin, pyraclostrobin, pyrametostrobin, pyraoxystrobin, ferbam,mancozeb, maneb, metiram, propineb, zineb, captafol, captan, fluoroimide, folpet, tolylfluanid, bordeauxmixture, copper oxide, mancopper, oxine-copper, nitrothal-isopropyl, edifenphos, iprobenphos,phosdiphen, tolclofos-methyl, anilazine, benthiavalicarb, blasticidin-S, chloroneb, chlorothalonil,cyflufenamid, cymoxanil, cyclobutrifluram, diclocymet, diclomezine, dicloran, diethofencarb, dimetho-morph, flumorph, dithianon, ethaboxam, etridiazole, famoxadone, fenamidone, fenoxanil, ferimzone,fluazinam, flumetylsulforim, fluopicolide, fluoxytioconazole, flusulfamide, fluxapyroxad, fenhexamid,fosetyl-aluminium, hymexazol, iprovalicarb, cyazofamid, methasulfocarb, metrafenone, pencycuron,phthalide, polyoxins, propamocarb, pyribencarb, proquinazid, pyroquilon, pyriofenone, quinoxyfen,quintozene, tiadinil, triazoxide, tricyclazole, triforine, validamycin, valifenalate, zoxamide,mandipropamid, flubeneteram, isopyrazam, sedaxane, benzovindiflupyr, pydiflumetofen, 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (3',4',5'-trifluoro-biphenyl-2-yl)-amide,isoflucypram, isotianil, dipymetitrone, 6-ethyl-5,7-dioxo-pyrrolo[4,5][1,4]dithiino[1,2-clisothiazole-3-carbonitrile, ~~ 2-(difluoromethyl)-N-[3-ethyl-1,1-dimethyl-indan-4-yl]pyridine-3-carboxamide, 4-(2,6-difluorophenyl)-6-methyl-5-phenyl-pyridazine-3-carbonitrile, (R)-3-(difluoromethyl)-1-methyl-N-[1,1,3-trimethylindan-4-yllpyrazole-4-carboxamide, 4-(2-bromo-4-fluoro-phenyl)-N-(2-chloro-8-fluoro-phenyl)-2,5-dimethyl-pyrazol-3-amine, 4- (2- bromo- 4- fluorophenyl) - N- (2- chloro- 6- fluorophenyl) - 1, 3-dimethyl- 1H- pyrazol- 5- amine, fluindapyr, coumethoxystrobin (jiaxiangjunzhi), Ivbenmixianan,dichlobentiazox, mandestrobin, 3-(4,4-diflucro-3,4-dinydro-3,3-dimethylisoquinolin-1-yl)quinolone, 2-[2-fluoro-6-[(8-fluoro-2-methyl-3-quinolyl)oxy]phenyllpropan-2-ol, oxathiapipralin, tert-butyl N-[6-[[[(1-methyltetrazol-5-yl)-phenyl-methylene]amino]oxymethyl]-2-pyridyljcarbamate, pyraziflumid,inpyrfluxam, trolprocarb, mefentrifluconazole, ipfentrifluconazole, 2-(difluoromethyl)-N-[(3R)-3-ethyl-1,1-dimethyl-indan-4-yl]pyridine-3-carboxamide, N'-(2,5-dimethyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine, N'-[4-(4,5-dichlorothiazol-2-yl)oxy-2.5-dimethyl-phenyl]-N-ethyl-N-methyl-formamidine, [2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yllacetyl]-4-piperidylthiazol-4-yl]-4,5-dihydroisoxazol-5-yl]-3-chloro-phenyl] methanesulfonate, but-3-ynyl N-[6-[[(Z)-[(1-methyltetrazol-5-yl)-phenyl-methylene]Jamino]oxymethyl]-2-pyridyljcarbamate, methyl N-[[5-[4-(2,4-dimethylphenyl)triazol-2-yl]-2-methyl-phenyllmethyljcarbamate, 3-chloro-6-methyl-5-phenyl-4-(2,4 6-trifluorophenyl)pyridazine,pyridachlometyl, 3-(difluoromethyl)-1-methyl-N-[1,1,3-trimethylindan-4-yl]pyrazole-4-carboxamide, 1-[2-[[1-(4-chlorophenyl)pyrazol-3-ylJoxymethyl]-3-methyl-phenyl]-4-methyl-tetrazol-5-one, 1-methyl-4-[3-methyl-2-[[2-methyl-4-(3,4,5-trimethylpyrazol-1-yl)phenoxy]methyllphenylltetrazol-5-one,aminopyrifen, ametoctradin, amisulbrom, penflufen, (Z,2E)-5-[1-(4-chlorophenyl)pyrazol-3-yljoxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide, florylpicoxamid, fenpicoxamid, metarylpicoxamid, tebufloquin, ipflufenoquin, quinofumelin, isofetamid, N-[2-[2,4-dichloro-phenoxy]phenyl]-3-(difluoromethyl)-1-methyl-pyrazole-4-carboxamide, N-[2-[2-chloro-4-(trifluoromethyl)phenoxy]phenyl]-3-(difluoromethyl)-1-methyl-pyrazole-4-carboxamide, benzothiostrobin, phenamacril, 5-amino-1,3 4-thiadiazole-2-thiol zinc salt(2:1), fluopyram, flufenoxadiazam, flutianil, fluopimomide, pyrapropoyne, picarbutrazox, 2-(difluoromethyl)-N-(3-ethyl-1,1-dimethyl-indan-4-yl)pyridine-3-carboxamide, 2- (difluoromethyl) - N-((3R) - 1, 1, 3- trimethylindan- 4- yl) pyridine- 3- carboxamide, 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1,2,4-triazol-1-ypropyl]-3-pyridyl]Joxylbenzonitrile, metyltetraprole, 2- (diflucromethyl) - N-{(3R) - 1, 1, 3-irimethylindan- 4- vl) pyridine- 3- carboxamide, o- (1, 1-dimethylethyl) - o [4(triflucromethoxy) [1, 1'- biphenyl] - 4- y1] -5- pyrimidinemethanol, fluoxapiprolin, enoxastrobin, 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1,2 4-triazol-1-yl) propyl]-3-pyridylJoxy] benzonitrile, 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-sulfanyl-1,2 4-triazol-1-yl) propyl]-3- pyridyl oxy]benzonitrile, 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-thioxo-4H-1,2 4-triazol-1-yhpropyl]-3pyridylJoxy]benzonitrile, trinexapac, coumoxystrobin, zhongshengmycin, thiodiazole copper, zincthiazole, amectotractin, iprodione, seboctylamine, N'-[5-bromo-2-methyl-6-[(1S)-1-methyl-2-propoxy-ethoxy]-3-pyridyl]-N-ethyl-N-methyl-formamidine, ~~ N'-[5-bromo-2-methyl-6-[(1R)-1-methyl-2-propoxy-ethoxy]-3-pyridyl]-N-ethyl-N-methyl-formamidine, N'-[5-bromo-2-methyl-6-(1-methyl-2-propoxy-ethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine, N'-[5-chloro-2-methyl-6-(1-methyl-2-propoxy-ethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine, N'-[5-bromo-2-methyl-6-(1-methyl-2-propoxy-ethoxy)-3-pyridyl]-N-isopropyl-N-methyl-formamidine (these compounds may be prepared from the methods described inWO2015 / 155075); N'-[5-bromo-2-methyl-6-(2-propoxypropoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine (this compound may be prepared from the methods described in IPCOM000249876D); N-isopropyl-N'-[5-methoxy-2-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-phenyl-ethyl)phenyl]-N-methyl-formamidine, N'-[4-(1-cyclopropyl-2,2,2-trifluoro-1-hydroxy-ethyl)-5-methoxy-2-methyl-phenyl]-N-isopropyl-N-methyl-formamidine (these compounds may be prepared from the methods described inWO02018 / 228896); N-ethyl-N'-[5-methoxy-2-methyl-4-[(2-trifluoromethyl)oxetan-2-yljphenyl]-N-methyl-formamidine, N-ethyl-N'-[5-methoxy-2-methyl-4-[(2-trifucromethyl)tetrahydrofuran-2-yllphenyl]-N-methyl-formamidine (these compounds may be prepared from the methods described inWO02019 / 110427); N-[(1R)-1-benzyl-3-chloro-1-methyl-but-3-enyl]-8-fluoro-quinoline-3-carboxamide, N-[(18)-1-benzyl-3-chloro-1-methyl-but-3-enyl]-8-fluoro-quinoline-3-carboxamide, N-[(1R)-1-benzyl-3,3,3-trifluoro-1-methyl-propyl]-8-fluoro-quinoline-3-carboxamide, N-[(1S)-1-benzyl-3,3,3-triflucro-1-methyl-propyl]-8-fluoro-quinoline-3-carboxamide, N-[(1R)-1-benzyl-1,3-dimethyl-butyl]-7,8-diflucro-quinoline-3-carboxamide, N-[(1S)-1-benzyl-1,3-dimethyl-butyl]-7,8-diflucro-quinoline-3-carboxamide, 8-fluoro-N-[(1R)-1-[(3-fluorophenyl)methyl]-1,3-dimethyl-butyljquinoline-3-carboxamide, 8-fluoro-N-[(1S)-1-[(3-fluorophenyl)methyl]-1,3-dimethyl-butyl]quinoline-3-carboxamide, N-[(1R)-1-benzyl-1,3-dimethyl-butyl]-8-fluoro-quinoline-3-carboxamide, N-[(1S)-1-benzyl-1,3-dimethyl-butyl]-8-fluoro-quinoline-3-carboxamide, N-((1R)-1-benzyl-3-chloro-1-methyl-but-3-enyl)-8-fluoro-quinoline-3-carboxamide, N-((18)-1-benzyl-3-chloro-1-methyl-but-3-enyl)-8-fluoro-quinoline-3-carboxamide (these compounds may be prepared from the methods describedin WO2017 / 153380); 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4,5-trifluoro-3, 3-dimethyl-isoquinoline, 1-(6,7-dimethylpyrazalo[1,5-a]pyridin-3-yl)-4,4 6-trifluoro-3,3-dimethyl-isoquinoline, 4 4-difluoro-3,3-dimethyl-1-(6-methylpyrazolo[1,5-a]pyridin-3-yl)isoquinaoline, 4 4-difluoro-3,3-dimethyl-1-(7-methylpyrazolo[1,5-a]pyridin-3-yl)isoquinoline, 1-(8-chloro-7-methyl-pyrazolo[1,5-a]pyridin-3-yl)-4 ,4-difluoro-3,3-dimethyl-isoquinoline (these compounds may be prepared from the methods describedin WO2017 / 025510); 1-(4,5-dimethylbenzimidazol-1-yl)-4,4,5-trifluorc-3, 3-dimethyl-isoquinoline, 1-(4,5-dimethylbenzimidazol-1-yl)-4,4-difluoro-3,3-dimethyl-isoquinoline, 6-chloro-4,4-difluoro-3,3-dimethyl-1-(4-methylbenzimidazol-1-yl)isoquinoline, 4 4-difluoro-1-(5-fluoro-4-methyl-benzimidazol-1-yl)-3,3-dimethyl-isoquinoline, 3-(4,4-difluoro-3,3-dimethyl-1-isoquinolyl)-7,8-dihydro-6H-cyclopentale]benzimidazole (these compounds may be prepared from the methods describedin WO2016 / 156085); N-methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yllphenyllmethyl]cyclopropanecarboxamide, N,2-dimethoxy-N-[[4-[5-(trifluoromethyl)- 1,2 4-oxadiazol-3-yllphenyllmethyllpropanamide, N-ethyl-2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yllphenyllmethyl]propanamide, 1-methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)- 1,2, 4-oxadiazol-3-yllphenyllmethyljurea, 1,3-dimethoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyljurea,3-ethyl-1-methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenylimethyl]urea, N-[[4-[5-(triffuoromethyl)-1,2,4-oxadiazol-3-yllphenyllmethyl]propanamide, 4 4-dimethyl-2-[[4-[5-(triffuoromethyl)-1,2,4-oxadiazol-3-yllphenylmethyllisoxazolidin-3-one, 5,5-dimethyl-2-[[4-[5-(triffuoromethyl)-1,2,4-oxadiazol-3-yllphenylmethyllisoxazolidin-3-one, ethyl 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyljmethyl]pyrazole-4-carboxylate, N,N-dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-ylphenyllmethyl]-1,2,4-triazol-3-amine (these compounds may be prepared from themethods described in WO 2017 / 055473, WO 2017 / 055469, WO 2017 / 093348 and WO2017 / 118689); 2-[6-(4-chlorophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol(this compound may be prepared from the methods described in WO 2017 / 029179); 2-[6-(4-bromophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (this compound may beprepared from the methods described in WO 2017 / 029179); 3-[2-(1-chlorocyclopropyl)-3-(2-fluorophenyl)-2-hydroxy-propyllimidazole-4-carbonitrile (this compound may be prepared from themethods described in WO 2016 / 156290); 3-[2-(1-chlorocyclopropyl)-3-(3-chloro-2-flucro-phenyl)-2-hydroxy-propyllimidazole-4-carbonitrile (this compound may be prepared from the methods describedin WO 2016 / 156290); (4-phenoxyphenylymethyl 2-amino-6-methyl-pyridine-3-carboxylate (this compound may be prepared from the methods described in WO 2014 / 006945); 2 6-Dimethyl-1H,5H-[1,4]dithiino[2,3-c:5 6-c'|dipyrrole-1,3,5,7(2H,6H)-tetrone (this compound may beprepared from the methods described in WO 2011 / 138281) N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yllbenzenecarbothioamide; N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yllbenzamide; (Z,2E)-5-[1-(2,4-dichlorophenyl)pyrazol-3-ylJoxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide (this compound may be prepared from the methods described in WO 2018 / 153707); N'-(2-chloro-5-methyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine; N'-[2-chloro-4-(2-fluorophenoxy)-5-methyl-phenyl]-N-ethyl-N-methyl-formamidine (this compound may be prepared from the methodsdescribed in WO 2016 / 202742); 2-(difluoromethyl)-N-[(3S)-3-ethyl-1,1-dimethyl-indan-4-yl|pyridine-3-carboxamide (this compound may be prepared from the methods described in WO 2014 / 095675); (5-methyl-2-pyridyl)-[4-[5-(trifluoromethyl)-1,2 4-oxadiazol-3-ylJphenyllmethanone, (3-methylisoxazol-5-yD)-[4-[5-(triflucromethyl)-1,2,4-oxadiazol-3-yllphenyllmethanone (these compounds may be preparedfrom the methods described in WO 2017 / 220485); 2-0xo0-N-propyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-ylJphenyllacetamide (this compound may be prepared from the methods described in WO2018 / 065414); ethyl 1-[[5-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-2-thienyllmethyl]pyrazole-4-carboxylate (this compound may be prepared from the methods described in WO 2018 / 158365); 2,2-difluoro-N-methyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyllacetamide, N-[(E)-methoxyiminomethyl]-4-[5- (trifluoromethyl)-1,2,4-oxadiazol-3-yllbenzamide, N-[(Z)-methoxyiminomethyl]-4-[5- (trifluoromethyl)-1,2 4-oxadiazol-3-yllbenzamide, N-[N-methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yllbenzamide (these compounds may beprepared from the methods described in WO 2018 / 202428).The compounds of the invention may also be used in combination with anthelmintic agents. Suchanthelmintic agents include, compounds selected from the macrocyclic lactone class of compoundssuch as ivermectin, avermectin, abamectin, emamectin, eprinomectin, doramectin, selamectin,moxidectin, nemadectin and milbemycin derivatives as described in EP-357460, EP-444964 and EP-594291. Additional anthelmintic agents include semisynthetic and biosynthetic avermectin / milbemycinderivatives such as those described in US-5015630, W0-9415944 and WO-9522552. Additionalanthelmintic agents include the benzimidazoles such as albendazole, cambendazole, fenbendazole,flubendazole, mebendazole, oxfendazole, oxibendazole, parbendazole, and other members of theclass. Additional anthelmintic agents include imidazothiazoles and tetrahydropyrimidines such astetramisole, levamisole, pyrantel pamoate, oxantel or morantel. Additional anthelmintic agents includeflukicides, such as ftriclabendazole and clorsulon and the cestocides, such as praziquantel andepsiprantel.The compounds of the invention may be used in combination with derivatives and analogues ofthe paraherquamide / marcfortine class of anthelmintic agents, as well as the antiparasitic oxazolinessuch as those disclosed in US-5478855, US- 4639771 and DE-19520936.The compounds of the invention may be used in combination with derivatives and analogues ofthe general class of dioxomorpholine antiparasitic agents as described in WO-9615121 and also withanthelmintic active cyclic depsipeptides such as those described in WO-9611945, WO-9319053, WO-9325543, EP-626375, EP-382173, WO-9419334, EP-382173, and EP-503538.The compounds of the invention may be used in combination with other ectoparasiticides; forexample, fipronil, pyrethroids; organophosphates; insect growth regulators such as lufenuron; ecdysoneagonists such as tebufenozide and the like; neonicotinoids such as imidacloprid and the like.The compounds of the invention may be used in combination with terpene alkaloids, for examplethose described in WO 95 / 19363 or WO 04 / 72086, particularly the compounds disclosed therein.Other examples of such biologically active compounds that the compounds of the invention maybe used in combination with include but are not restricted to the following: Organophosphates: acephate,azamethiphos, azinphos-ethyl, azinphos- methyl, bromophos, bromophos-ethyl, cadusafos,chlorethoxyphos, chlorpyrifos, chlorfenvinphos, chlormephos, demeton, demeton-S-methyl, demeton-S-methyl sulphone, dialifos, diazinon, dichlorvos, dicrotophos, dimethoate, disulfoton, ethion,ethoprophos, etrimfos, famphur, fenamiphos, fenitrothion, fensulfothion, fenthion, flupyrazofos, fonofos,formothion, fosthiazate, heptenophos, isazophos, isothioate, isoxathion, malathion, methacriphos,methamidophos, methidathion, methyl-parathion, mevinphas, manocrotophos, naled, omethoate,oxydemeton-methyl, paraoxon, parathion, parathion-methyl, phenthoate, phosalone, phosfolan,phosphocarb, phosmet, phosphamidon, phorate, phoxim, pirimiphos, pirimiphos-methyl, profenofos,propaphos, proetamphas, prothiofos, pyraclofos, pyridapenthion, quinalphos, sulprophos, temephos,terbufos, tebupirimfos, tetrachlorvinphos, thimeton, triazophos, trichlorfon, vamidothion.Carbamates: alanycarb, aldicarb, 2-sec-butylphenyl methylcarbamate, benfuracarb, carbaryl,carbofuran, carbosulfan, cloethocarb, ethiofencarb, fenoxycarb, fenthiocarb, furathiocarb, HCN-801,isoprocarb, indoxacarb, methiocarb, methamyl, 5-methyl-m-cumenylbutyryl(methyl)carbamate, oxamyl,pirimicarb, propoxur, thiodicarb, thiofanox, triazamate, UC-51717.Pyrethroids: acrinathin, allethrin, alphametrin, 5-benzyl-3-furylmethyl (E)-(1R)-cis-2,2-dimethyl-3-(2-oxothiolan-3-ylidenemethyl)cyclopropanecarboxylate, bifenthrin, beta-cyfluthrin, cyfluthrin, a-cypermethrin, beta -cypermethrin, bioallethrin, bioallethrin((S)-cyclopentylisomer), bioresmethrin,bifenthrin, NCI-85193, cycloprothrin, cyhalothrin, cythithrin, cyphenothrin, deltamethrin, empenthrin,esfenvalerate, ethofenprox, fenfluthrin, fenpropathrin, fenvalerate, flucythrinate, flumethrin, fluvalinate(D isomer), imiprothrin, cyhalothrin, lambda-cyhalothrin, permethrin, phenothrin, prallethrin, pyrethrins(natural products), resmethrin, tetramethrin, transfluthrin, theta-cypermethrin, silafluofen, t-fluvalinate,tefluthrin, tralomethrin, Zeta-cypermethrin.Arthropod growth regulators: a) chitin synthesis inhibitors: benzoylureas: chlorfluazuron,diflubenzuron, fluazuron, flucycloxuron, flufenoxuron, hexaflumuron, Iufenuron, novaluron,teflubenzuron, triflumuron, buprofezin, diofenolan, hexythiazox, etoxazole, chlorfentazine; b) ecdysoneantagonists: halofenozide, methoxyfenozide, tebufenozide; c) juvenoids: pyriproxyfen, methoprene(including S-methoprene), fenoxycarb; d) lipid biosynthesis inhibitors: spirodiclofen.Other antiparasitics: acequinocyl, amitraz, AKD-1022, ANS-118, azadirachtin, Bacillusthuringiensis, bensultap, bifenazate, binapacryl, bromopropylate, BTG-504, BTG-505, camphechlor,cartap, chlorobenzilate, chlordimeform, chlorfenapyr, chromafenozide, clothianidine, cyromazine,diacloden, diafenthiuron, DBI-3204, dinactin, dihydroxymethyldihydroxypyrrolidine, dinobuton, dinocap,endosulfan, ethiprole, ethofenprox, fenazaquin, flumite, MTI-800, fenpyroximate, fluacrypyrim,flubenzimine, flubrocythrinate, flufenzine, flufenprox, fluproxyfen, halofenprox, hydramethylnon, 1KI-220,kanemite, NC-196, neem guard, nidincrterfuran, nitenpyram, SD-35651, WL-108477, pirydaryl,propargite, protrifenbute, pymethrozine, pyridaben, pyrimidifen, NC-1111, R-195,RH-0345, RH-2485,RYI-210, S$-1283, S-1833, SI-8601, silafluofen, silomadine, spinosad, tebufenpyrad, tetradifon,tetranactin, thiacloprid, thiocyclam, thiamethoxam, tolfenpyrad, triazamate, triethoxyspinosyn, trinactin,verbutin, vertalec, YI-5301.Biological agents: Bacillus thuringiensis ssp aizawai, kurstaki, Bacillus thuringiensis deltaendotoxin, baculovirus, entomopathogenic bacteria, virus and fungi.Bactericides: chlortetracycline, oxytetracycline, streptomycin.Other biological agents: enrofloxacin, febantel, penethamate, moloxicam, cefalexin, kanamycin,pimobendan, clenbuterol, omeprazole, tiamulin, benazepril, pyriprole, cefquinome, florfenicol, buserelin,cefovecin, tulathromycin, ceftiour, carprofen, metaflumizone, praziquarantel, triclabendazole.Another aspect of invention is related to the use of a compound of formula (I) or of a preferredindividual compound as above-defined, of a composition comprising at least one compound of formula(I) or at least one preferred individual compound as above-defined, or of a fungicidal or insecticidalmixture comprising at least one compound of formula (I) or at least one preferred individual compoundas above-defined, in admixture with other fungicides or insecticides as described above, for controllingor preventing infestation of plants, e.g. useful plants such as crop plants, propagation material thereof,e.g. seeds, harvested crops, e.g., harvested food crops, or non-living materials by insects or byphytopathogenic microorganisms, preferably fungal organisms.A further aspect of invention is related to a method of controlling or preventing an infestation ofplants, e.g., useful plants such as crop plants, propagation material thereof, e.g. seeds, harvested crops,e.g. harvested food crops, or of non-living materials by insects or by phytopathogenic or spoilagemicroorganisms or organisms potentially harmful to man, especially fungal organisms, which comprisesthe application of a compound of formula (I) or of a preferred individual compound as above-defined asactive ingredient to the plants, to parts of the plants or to the locus thereof, to the propagation materialthereof, or to any part of the non-living materials.Controlling or preventing means reducing infestation by insects or by phytopathogenic or spoilagemicroorganisms or organisms potentially harmful to man, especially fungal organisms, to such a levelthat an improvement is demonstrated.A preferred method of controlling or preventing an infestation of crop plants by phytopathogenicmicroorganisms, especially fungal organisms, or insects which comprises the application of a compoundof formula (I), or an agrochemical composition which contains at least one of said compounds, is foliarapplication. The frequency of application and the rate of application will depend on the risk of infestationby the corresponding pathogen or insect. However, the compounds of formula (I) can also penetrate theplant through the roots via the soil (systemic action) by drenching the locus of the plant with a liquidformulation, or by applying the compounds in solid form to the soil, e.g., in granular form (soilapplication). In crops of water rice such granulates can be applied to the flooded rice field. Thecompounds of formula (I) may also be applied to seeds (coating) by impregnating the seeds or tuberseither with a liquid formulation of the fungicide or coating them with a solid formulation.A formulation, e.g. a composition containing the compound of formula (I), and, if desired, a solidor liquid adjuvant or monomers for encapsulating the compound of formula (I), may be prepared in aknown manner, typically by intimately mixing and / or grinding the compound with extenders, for examplesolvents, solid carriers and, optionally, surface active compounds (surfactants).Advantageous rates of application are normally from 5g to 2kg of active ingredient (a.i.) perhectare (ha), preferably from 10g to 1kg a.i. / ha, most preferably from 20g to 600g a.i. / ha. When usedas seed drenching agent, convenient dosages are from 10mg to 1g of active substance per kg of seeds.When the combinations of the present invention are used for treating seed, rates of 0.001 to 50 ¢gof a compound of formula (I) per kg of seed, preferably from 0.01 to 10g per kg of seed are generallysufficient.The compositions of the invention may be employed in any conventional form, for example in theform of a twin pack, a powder for dry seed treatment (DS), an emulsion for seed treatment (ES), aflowable concentrate for seed treatment (FS), a solution for seed treatment (LS), a water dispersiblepowder for seed treatment (WS), a capsule suspension for seed treatment (CF), a gel for seed treatment(GF), an emulsion concentrate (EC), a suspension concentrate (SC), a suspo-emulsion (SE), a capsulesuspension (CS), a water dispersible granule (WG), an emulsifiable granule (EG), an emulsion, waterin oil (EQ), an emulsion, oil in water (EW), a micro-emulsion (ME), an oil dispersion (OD), an oil miscibleflowable (OF), an oil miscible liquid (OL), a soluble concentrate (SL), an ultra-low volume suspension(SU), an ultra-low volume liquid (UL), a technical concentrate (TK), a dispersible concentrate (DC), awettable powder (WP) or any technically feasible formulation in combination with agriculturallyacceptable adjuvants.Such compositions may be produced in conventional manner, e.g., by mixing the active ingre-dients with appropriate formulation inerts (diluents, solvents, fillers and optionally other formulatingingredients such as surfactants, biocides, anti-freeze, stickers, thickeners and compounds that provideadjuvancy effects). Also conventional slow release formulations may be employed where long lastingefficacy is intended. Particularly formulations to be applied in spraying forms, such as water dispersibleconcentrates (e.g. EC, SC, DC, OD, SE, EW, EC and the like), wettable powders and granules, maycontain surfactants such as wetting and dispersing agents and other compounds that provide adjuvancyeffects, e.g. the condensation product of formaldehyde with naphthalene sulphonate, analkylarylsulphonate, a lignin sulphonate, a fatty alkyl sulphate, and ethoxylated alkylphenol and anethoxylated fatty alcohol.A seed dressing formulation is applied in a manner known per se to the seeds employing thecombination of the invention and a diluent in suitable seed dressing formulation form, e.g., as anaqueous suspension or in a dry powder form having good adherence to the seeds. Such seed dressingformulations are known in the art. Seed dressing formulations may contain the single active ingredientsor the combination of active ingredients in encapsulated form, e.g. as slow release capsules ormicrocapsules.In general, the formulations include from 0.01 to 90% by weight of active agent, from 0 to 20%agriculturally acceptable surfactant and 10 to 99.99% solid or liquid formulation inerts and adjuvant(s),the active agent consisting of at least the compound of formula (I) together with component (B) and (C),and optionally other active agents, particularly microbiocides or conservatives or the like. Concentratedforms of compositions generally contain in between about 2 and 80%, preferably between about 5 and70% by weight of active agent. Application forms of formulation may for example contain from 0.01 to20% by weight, preferably from 0.01 to 5% by weight of active agent. Whereas commercial products willpreferably be formulated as concentrates, the end user will normally employ diluted formulations.Table 1 below illustrates examples of individual compounds of formula (I) according to the invention.Table A-1 provides 48 compounds A-1.001 to A-1.048 of formula (Ib)wherein A is N, R" is hydrogen, R' is tetrahydrofuran-3-yl, R? is hydrogen, and R1, R, R and R areas defined in Table 1.Table 1: Individual compounds of formula (I) according to the inventionTable A-2 provides 48 compounds A-2.001 to A-2.048 of Formula (Ib), wherein A is N, R7 is hydrogen,R! is tetrahydrofuran-3-yl, R? is fluoro, and R1, R%, R and R? are as defined in Table 1.Table A-3 provides 48 compounds A-3.001 to A-3.048 of Formula (Ib), wherein A is N, R? is hydrogen,R'is tetrahydrofuran-2-yl, R? is hydrogen, and R1, R R and R are as defined in Table 1.Table A-4 provides 48 compounds A-4.001 to A-4.048 of Formula (Ib), wherein A is N, R7 is hydrogen,R'is tetrahydrofuran-2-yl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-5 provides 48 compounds A-5.001 to A-5.048 of Formula (Ib), wherein A is N, Ris hydrogen,R'is oxetane-3-yl, R? is hydrogen, and R* R, R and R are as defined in Table 1.Table A-6 provides 48 compounds A-6.001 to A-6.048 of Formula (Ib), wherein A is N, R? is hydrogen,R'is oxetane-3-yl, R? is fluoro, and R* R?%, R and R are as defined in Table 1.Table A-7 provides 48 compounds A-7.001 to A-7.048 of Formula (Ib), wherein A is N, R is hydrogen,R'is 1-methylsulfonylethyl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-8 provides 48 compounds A-8.001 to A-8.048 of Formula (Ib), wherein A is N, R7 is hydrogen,R'is 1-methylsulfonylethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-9 provides 48 compounds A-9.001 to A-9.048 of Formula (Ib), wherein A is N, R7 is hydrogen,R'is 1-methylsulfinylethyl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-10 provides 48 compounds A-10.001 to A-10.048 of Formula (Ib), wherein A is N, R? ishydrogen, R' is 1-methylsulfinylethyl, R? is fluoro, and R* R R and R are as defined in Table 1.Table A-11 provides 48 compounds A-11.001 to A-11.048 of Formula (Ib), wherein A is N, R? ishydrogen, R' is 1-methylsulfanylethyl, R? is hydrogen, and R*, R% R and R are as defined in Table 1.Table A-12 provides 48 compounds A-12.001 to A-12.048 of Formula (Ib), wherein A is N, R? ishydrogen, R' is 1-methylsulfanylethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-13 provides 48 compounds A-13.001 to A-13.048 of Formula (Ib), wherein A is N, R"hydrogen, R' is 1-methaxyethyl, R? is hydrogen, and R* R, R and R are as defined in Table 1.Table A-14 provides 48 compounds A-14.001 to A-14.048 of Formula (Ib), wherein A is N, R"hydrogen, R' is 1-methaxyethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-15 provides 48 compounds A-15.001 to A-15.048 of Formula (Ib), wherein A is N, R?hydrogen, R' is 1-isopropoxyethyl, R? is hydrogen, and R*, R, Rf and R are as defined in Table 1.Table A-16 provides 48 compounds A-16.001 to A-16.048 of Formula (Ib), wherein A is N, R7hydrogen, R' is 1-isopropoxyethyl, R? is fluoro, and R*, R5, R and R are as defined in Table 1.Table A-17 provides 48 compounds A-17.001 to A-17.048 of Formula (Ib), wherein A is N, R"hydrogen, R' is 1-tert-butoxyethyl, R? is hydrogen, and R*, R%, R and R are as defined in Table 1.Table A-18 provides 48 compounds A-18.001 to A-18.048 of Formula (Ib), wherein A is N, R"hydrogen, R' is 1-tert-butoxyethyl, R? is fluoro, and R*, R%, R and R are as defined in Table 1.Table A-19 provides 48 compounds A-19.001 to A-19.048 of Formula (Ib), wherein A is N, R7hydrogen, R' is isopropoxymethyl, R? is hydrogen, and R* R, R and R are as defined in Table 1.Table A-20 provides 48 compounds A-20.001 to A-20.048 of Formula (Ib), wherein A is N, R'hydrogen, R' is isopropoxymethyl, R? is fluoro, and R*, R R and R are as defined in Table 1.Table A-21 provides 48 compounds A-21.001 to A-21.048 of Formula (Ib), wherein A is N, R"hydrogen, R' is tert-butoxymethyl, R? is hydrogen, and R?*, R, R and R are as defined in Table 1.Table A-22 provides 48 compounds A-22.001 to A-22.048 of Formula (Ib), wherein A is N, R"hydrogen, R' is tert-butoxymethyl, R? is fluoro, and R*, R R and R are as defined in Table 1.Table A-23 provides 48 compounds A-22.001 to A-23.048 of Formula (Ib), wherein A is N, R7 is -C(O)2CHs, R' is tetrahydrofuran-3-yl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-24 provides 48 compounds A-24.001 to A-24.048 of Formula (Ib), wherein A is N, R'is -C(0)2CHs, R'is tetrahydrofuran-3-yl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-25 provides 48 compounds A-25.001 to A-25.048 of Formula (Ib), wherein A is N, R7 is -C(O)2CHs, R' is tetrahydrofuran-2-yl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-26 provides 48 compounds A-26.001 to A-26.048 of Formula (Ib), wherein A is N, R7 is -C(0)2CHs, R'is tetrahydrofuran-2-yl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-27 provides 48 compounds A-27.001 to A-27.048 of Formula (Ib), wherein A is N, R7 is -C(O)2CHs, R' is oxetane-3-yl, R? is hydrogen, and R*, R, R and R? are as defined in Table 1.Table A-28 provides 48 compounds A-28.001 to A-28.048 of Formula (Ib), wherein A is N, R" is -C(0)2CHz, R'is oxetane-3-yl, R? is fluoro, and R*, R R and R are as defined in Table 1.Table A-29 provides 48 compounds A-29.001 to A-29.048 of Formula (Ib), wherein A is N, R7 is -C(0)2CHs, R'is 1-methylsulfonylethyl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-30 provides 48 compounds A-30.001 to A-30.048 of Formula (Ib), wherein A is N, R7 is -C(0)2CHs, R'is 1-methylsulfonylethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-31 provides 48 compounds A-31.001 to A-31.048 of Formula (Ib), wherein A is N, R7 is -C(O)2CHs, R' is 1-methylsulfinylethyl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-32 provides 48 compounds A-32.001 to A-32.048 of Formula (Ib), wherein A is N, R" is -C(O)2CHs, R' is 1-methylsulfinylethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-33 provides 48 compounds A-33.001 to A-33.048 of Formula (Ib), wherein A is N, R'is -C(0)2CHs, R'is 1-methylsulfanylethyl, R? is hydrogen, and R*, R5, R and R are as defined in Table 1.Table A-34 provides 48 compounds A-34.001 to A-34.048 of Formula (Ib), wherein A is N, R'is -C(0O)2CHs, R' is 1-methylsulfanylethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-35 provides 48 compounds A-35.001 to A-35.048 of Formula (Ib), wherein A is N, R'is -C(0)2CHs, R'is 1-methoxyethyl, RZ is hydrogen, and R4, R5, R6 and R7 are as defined in Table 1.Table A-36 provides 48 compounds A-36.001 to A-36.048 of Formula (Ib), wherein A is N, R" is -C(0)2CHs, R'is 1-methoxyethyl, R? is fluoro, and R?*, R, R and R are as defined in Table 1.Table A-37 provides 48 compounds A-37.001 to A-37.048 of Formula (Ib), wherein A is N, R" is -C(O)2CHs, R' is 1-isopropoxyethyl, R? is hydrogen, and R*, R R and R are as defined in Table 1.Table A-38 provides 48 compounds A-38.001 to A-38.048 of Formula (Ib), wherein A is N, R7 is -C(O):CHs, R' is 1-isopropoxyethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-39 provides 48 compounds A-39.001 to A-39.048 of Formula (Ib), wherein A is N, R"C(O)2CHs, R' is 1-tert-butoxyethyl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-40 provides 48 compounds A-40.001 to A-40.048 of Formula (Ib), wherein A is N, R"C(0)2CHs, R'is 1-tert-butoxyethyl, R? is fluoro, and R* R, R and R are as defined in Table 1.Table A-41 provides 48 compounds A-41.001 to A-41.048 of Formula (Ib), wherein A is N, R"C(O)2CHs, R'is isopropoxymethyl, R? is hydrogen, and R*, R R and R are as defined in Table 1.Table A-42 provides 48 compounds A-42.001 to A-42.048 of Formula (Ib), wherein A is N, R7 iC(0)2CHs, R' is isopropoxymethyl, R? is fluoro, and R*, R, R and R? are as defined in Table 1.Table A-43 provides 48 compounds A-43.001 to A-43.048 of Formula (Ib), wherein A is N, R7 iC(O)zCHs, R'is tert-butoxymethyl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-44 provides 48 compounds A-44.001 to A-44.048 of Formula (Ib), wherein A is N, R7C(O)2CHs, R' is tert-butoxymethyl, R? is fluoro, and R*, R%, R and R are as defined in Table 1.Table A-45 provides 48 compounds A-45.001 to A-45.048 of Formula (Ib), wherein A is N, R'isC(0)2CH2CHs, R' is tetrahydrofuran-3-yl, R? is hydrogen, and R*, R, R and R are as defined in Table1.Table A-46 provides 48 compounds A-46.001 to A-46.048 of Formula (Ib), wherein A is N, R" is -C(0)2CHzCHs, R' is tetrahydrofuran-3-yl, R? is fluoro, and R*, R%, R and R are as defined in Table 1.Table A-47 provides 48 compounds A-47.001 to A-47.048 of Formula (Ib), wherein A is N, R" is -C(O)2CH2CHs, R'is tetrahydrofuran-2-yl, R? is hydrogen, and R*, R, R and R are as defined in Table1.Table A-48 provides 48 compounds A-48.001 to A-48.048 of Formula (Ib), wherein A is N, R' is -C(0Q)2CH2CHs, R' is tetrahydrofuran-2-yl, R? is fluoro, and R*, R, R and R? are as defined in Table 1.Table A-49 provides 48 compounds A-49.001 to A-49.048 of Formula (Ib), wherein A is N, R" is -C(0O)2CH2CHs, R is oxetane-3-yl, R? is hydrogen, and R*, R R and R? are as defined in Table 1.Table A-50 provides 48 compounds A-50.001 to A-50.048 of Formula (Ib), wherein A is N, R7 is -C(O)2CHzCHs, Ris oxetane-3-yl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-51 provides 48 compounds A-51.001 to A-51.048 of Formula (Ib), wherein A is N, R'is -C(0)2CH2CHs, R' is 1-methylsulfonylethyl, R? is hydrogen, and R*, R%, R and R are as defined in Table1.Table A-52 provides 48 compounds A-52.001 to A-52.048 of Formula (Ib), wherein A is N, R7 is -C(O)2CH2CHs3, R" is 1-methylsulfonylethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-53 provides 48 compounds A-53.001 to A-53.048 of Formula (Ib), wherein A is N, R7 is -C(O)2CHzCHs, R'is 1-methylsulfinylethyl, R? is hydrogen, and R*, R, R and R are as defined in Table1.Table A-54 provides 48 compounds A-54.001 to A-54.048 of Formula (Ib), wherein A is N, R" is -C(0)2CH2CHs, R' is 1-methylsulfinylethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-55 provides 48 compounds A-55.001 to A-55.048 of Formula (Ib), wherein A is N, R7 is -C(0)2CH2CHs, R' is 1-methylsulfanylethyl, R? is hydrogen, and R*, R, R and R are as defined in Table1.Table A-56 provides 48 compounds A-56.001 to A-56.048 of Formula (Ib), wherein A is N, R' is -C(0)2CH2CHs, R' is 1-methylsulfanylethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-57 provides 48 compounds A-57.001 to A-57.048 of Formula (Ib), wherein A is N, R'is -C(0)2CH2CHs, R' is 1-methoxyethyl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-58 provides 48 compounds A-58.001 to A-58.048 of Formula (Ib), wherein A is N, R" is -C(0)2CH2CHs, R' is 1-methoxyethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-59 provides 48 compounds A-59.001 to A-59.048 of Formula (Ib), wherein A is N, R7 is -C(0O)2CH2CH3, R' is 1-isopropoxyethyl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-60 provides 48 compounds A-60.001 to A-60.048 of Formula (Ib), wherein A is N, R" is -C(0)2CH:CHs, R" is 1-isopropoxyethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-61 provides 48 compounds A-61.001 to A-61.048 of Formula (Ib), wherein A is N, R7 is -C(O)2CHzCHs, R' is 1-tert-butoxyethyl, R? is hydrogen, and R*, R, R and R? are as defined in Table 1.Table A-62 provides 48 compounds A-62.001 to A-62.048 of Formula (Ib), wherein A is N, R7 is -C(O)2CH2CHs, R' is 1-tert-butoxyethyl, R? is fluoro, and R*, R, R¢ and R are as defined in Table 1.Table A-63 provides 48 compounds A-63.001 to A-63.048 of Formula (Ib), wherein A is N, R'is -C(0)2CH2CHs, R' is isapropoxymethyl, R? is hydrogen, and R* R5, R and R? are as defined in Table 1.Table A-64 provides 48 compounds A-64.001 to A-64.048 of Formula (Ib), wherein A is N, R7 is -C(0)2CH2CH3, R' is isopropoxymethyl, R? is fluara, and R*, R, R and R are as defined in Table 1.Table A-65 provides 48 compounds A-65.001 to A-65.048 of Formula (Ib), wherein A is N, R7 is -C(0O)2CH2CHs, R' is tert-butoxymethyl, R? is hydrogen, and R*, R, R and R are as defined in Table 1.Table A-66 provides 48 compounds A-66.001 to A-66.048 of Formula (Ib), wherein A is N, R7 is -C(0O)2CHzCHs, R' is tert-butoxymethyl, R? is fluoro, and R*, R, R and R are as defined in Table 1.Table A-87 provides 12 compounds A-67.001 to A-66.012 of Formula (Ib), wherein A is N, R? ishydrogen, R' is tetrahydropyran-4-yl, R? is hydrogen, and R*, R%, R and R are as defined in Table 1.Table A-88 provides 12 compounds A-68.001 to A-68.012 of Formula (Ib), wherein Ais N, R" ishydrogen, R' is tetrahydropyran-4-yl, R? is fluoro, and R*, R Rf and R are as defined in Table 1.Formulation ExamplesWettable powders a) b) c)active ingredient [compound of formula (1)] 25% 50 % 75 %sodium lignosulfonate 5% 5% -sodium lauryl sulfate 3% - 5%sodium diisobutylnaphthalenesulfonate - 6% 10%phenol polyethylene glycol ether - 2% -(7-8 mol of ethylene oxide)highly dispersed silicic acid 59% 10% 10%Kaolin 62 % 27% -The active ingredient is thoroughly mixed with the adjuvants and the mixture is thoroughly ground in asuitable mill, affording wettable powders that can be diluted with water to give suspensions of the desiredconcentration.Powders for dry seed treatment a) b) Cc)active ingredient [compound of formula (1)] 25% 50 % 75 %light mineral oll 5% 5% 5%highly dispersed silicic acid 5% 5% -Kaolin 65 % 40 % -Talocum - 20 %The active ingredient is thoroughly mixed with the adjuvants and the mixture is tharoughly ground in asuitable mill, affording powders that can be used directly for seed treatment.Emulsifiable concentrateactive ingredient [compound of formula (I)] 10 %octylphenol polyethylene glycol ether 3%(4-5 mol of ethylene oxide)calcium dodecylbenzenesulfonate 3%castor oil polyglycol ether (35 mol of ethylene oxide) 4%Cyclohexanone 30 %xylene mixture 50 %Emulsions of any required dilution, which can be used in plant protection, can be obtained from thisconcentrate by dilution with water.Dusts a) b) Active ingredient [compound of formula (I)] 5% 6% 4%talcum 95 % - -Kaolin - 94 % -mineral filler - - 96 %Ready-for-use dusts are obtained by mixing the active ingredient with the carrier and grinding themixture in a suitable mill. Such powders can also be used for dry dressings for seed.Extruder granulesActive ingredient [compound of formula (1)] 15%sodium lignosulfonate 2%carboxymethylcellulose 1%Kaolin 82%The active ingredient is mixed and ground with the adjuvants, and the mixture is moistened with water.The mixture is extruded and then dried in a stream of air.Coated granulesActive ingredient [compound of formula (I)] 8%polyethylene glycol (mol. wt. 200) 3%Kaolin 89 %The finely ground active ingredient is uniformly applied, in a mixer, to the kaolin moistened withpolyethylene glycol. Non-dusty coated granules are obtained in this manner.Suspension concentrateactive ingredient [compound of formula (1)] 40 %propylene glycol 10 %nanylphenol polyethylene glycol ether (15 mol of ethylene oxide) 6%Sodium lignosulfonate 10%carboxymethylcellulose 1%silicone oil (in the form of a 75 % emulsion in water) 1%Water 32%The finely ground active ingredient is intimately mixed with the adjuvants, giving a suspensionconcentrate from which suspensions of any desired dilution can be obtained by dilution with water. Usingsuch dilutions, living plants as well as plant propagation material can be treated and protected againstinfestation by microorganisms, by spraying, pouring or immersion.Flowable concentrate for seed treatmentactive ingredient [compound of formula (1)] 40 %propylene glycol 5%copolymer butanol PO / EO 2%tristyrenephenale with 10-20 moles EO 2%1,2-benzisothiazolin-3-one (in the form of a 20% solution in water) 0.5%monoazo-pigment calcium salt 5%Silicone oil (in the form of a 75 % emulsion in water) 0.2%Water 45.3 %The finely ground active ingredient is intimately mixed with the adjuvants, giving a suspensionconcentrate from which suspensions of any desired dilution can be obtained by dilution with water. Usingsuch dilutions, living plants as well as plant propagation material can be treated and protected againstinfestation by microorganisms, by spraying, pouring or immersion.Slow Release Capsule Suspension28 parts of a combination of the compound of formula (I) are mixed with 2 parts of an aromaticsolvent and 7 parts of toluene diisocyanate / polymethylene-polyphenylisocyanate-mixture (8:1). Thismixture is emulsified in a mixture of 1.2 parts of polyvinyl alcohol, 0.05 parts of a defoamer and 51.6parts of water until the desired particle size is achieved. To this emulsion a mixture of 2.8 parts 1,6-diaminohexane in 5.3 parts of water is added. The mixture is agitated until the polymerization reactionis completed.The obtained capsule suspension is stabilized by adding 0.25 parts of a thickener and 3 parts of adispersing agent. The capsule suspension formulation contains 28% of the active ingredients. Themedium capsule diameter is 8-15 microns.The resulting formulation is applied to seeds as an aqueous suspension in an apparatus suitablefor that purpose.ExamplesThe Examples which fallow serve to illustrate the invention. The compounds of the invention canbe distinguished from known compounds by virtue of greater efficacy at low application rates, which canbe verified by the person skilled in the art using the experimental procedures outlined in the Examples,using lower application rates if necessary, for example 50 ppm, 12.5 ppm, 6 ppm, 3 ppm, 1.5 ppm, 0.8ppm or 0.2 ppm.Compounds of formula (I) may possess any number of benefits including, inter alia, advantageouslevels of biological activity for protecting plants against diseases that are caused by fungi or superiorproperties for use as agrochemical active ingredients (for example, greater biological activity, anadvantageous spectrum of activity, an increased safety profile (including improved crop tolerance),improved physico-chemical properties, or increased biodegradability).List of Abbreviations°C = degrees Celsius, CDCl: = chloroform-d,d = doublet, DCM = dichloromethane, DMF =dimethylformamide, HATU = 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxidhexafluorophosphate, m = multiplet, MHz = megahertz, N = normal, RT = room temperature, s = singletGeneralThroughout this description, temperatures are given in degrees Celsius (°C) and "m.p." means meltingpoint. LC / MS means Liquid Chromatography Mass Spectrometry and the description of the apparatusand the method is:Method A: ACQUITY UPLC from Waters, Waters UPLC HSS T3, 1.8 mm particle size, 30 x 2.1 mmcolumn, 0.85 mL / min., 60 °C, H20 / MeOH 95:5 + 0.05% HCOOH (90%) / CH3CN + 0.05% HCOOH(10%) - 1.2 min. - CH3CN + 0.05% HCOOCH (100%) - 0.30 min., ACQUITY SQD Mass Spectrometerfrom Waters, ionization method: electrospray (ESI), Polarity: positive ions, Capillary (kV) 3.00, Cone (V)30.00, Extractor (V) 2.00, Source Temperature (°C) 150, Desolvation Temperature (°C) 350, Cone GasFlow (L / Hr) 0, Desolvation Gas Flow (L / Hr) 650).Method B: ACQUITY UPLC from Waters, Waters UPLC HSS T3, 1.8 mm particle size, 30 x 2.1 mmcolumn, 0.85 mL / min., 60 °C, H20 / MeOH 95:5 + 0.05% HCOOH (90%) / CH3CN + 0.05% HCOOH(10%) - 2.7 min. = CH3CN + 0.05% HCOOH (100%) - 0.30 min., ACQUITY SQD Mass Spectrometerfrom Waters, ionization method: electrospray (ESI), Polarity: positive ions, Capillary (kV) 3.00, Cone (V)30.00, Extractor (VV) 2.00, Source Temperature (°C) 150, Desolvation Temperature (°C) 350, Cone GasFlow (L / Hr) 0, Desolvation Gas Flow (L / Hr) 650).Method C: ACQUITY Mass Spectrometer from Waters Corporations (SQD or SQDI| Single quadrupolemass spectrometer) equipped with an electrospray source (Polarity: positive or negative ions, Capillary:3.0 kV, Cone: 30V, Extractor. 3.00 V, Source Temperature: 150°C, Desolvation Temperature: 400°C,Cone Gas Flow: 60 L / hr, Desolvation Gas Flow: 700 L / hr, Mass range: 140 to 800 Da) and an ACQUITYUPLC from Waters Corporations with solvent degasser, binary pump, heated column compartment anddiode-array detector. Column; Waters UPLC HSS T3, 1.8 um, 30 x 2.1 mm, Temp: 60 °C, DADWavelength range (nm): 210 to 400, Solvent Gradient: A = Water / Methanol 9:1 + 0.1% formic acid, B=Acetonitrile + 0.1% formic acid, gradient: 0-100% B in 2.5 min; Flow (ml / min) 0.75.).Example 1: Preparation of 2-[(2,6-difluoro-4-pyridyl)-(tetrahydrofuran-3-carbonyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (Example P-2, Table 2) and 2-[(2,6-difluoro-4-pyridyl)-(tetrahydrofuran-3-carbonyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-N-(tetrahydrofuran-3-carbonylthiazole-4-carboxamide (Example P-1, Table 2)geegs(Compound P-3, Table 2)(Compound P-1, Table 2)A solution of tetrahydrofuran-3-carboxylic acid (0.174 g, 0.143 mL, 1.48 mmol) in DCM (9 mL) underargon was treated with 1 drop of DMF, followed by oxalyl chloride (0.192 g, 0.13 mL, 1.48 mmol). Themixture was stirred for 30 minutes at RT under argon to give tetrahydrofuran-3-carbonyl chloride. Tothis DCM solution were added 2-[(2,6-difluoro-4-pyridylyamino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (0.350 g, 0.993 mmol, prepared as described in WO 2019 / 105933), followed bytriethylamine (0.308 g, 0.42 mL, 2.98 mmol), under argen at RT. The resulting pale-yellow solution wasstirred for 2.5 hours under argon at RT upon which time LCMS analysis showed reaction completion.The reaction mixture was treated with Isolute and concentrated in vacuo. Purification by Flashchromatography eluting with ethyl acetate / cyclohexane gave a mixture of two products which was furtherpurified by reverse phase chromatography to give as the first eluted product 2-[(2,6-difluoro-4-pyridyl)-(tetrahydrofuran-3-carbonyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide(Example P-2, Table 2) as a white powder.TH NMR (400 MHz, CDCl): 5 ppm 0.94 (s, 3H) 1.13 (5, 3 H) 1.49 - 1.59 (m, 2H) 1.65 - 1.78 (Mm, 1 H)1.95-215(m, 1H) 219-230 (m, 1 H) 2.30 - 2.40 (m, 1 H) 2.81 (s, 3 H) 2.99 - 3.14 (m, 1 H) 3.80 -3.88 (m, 1 H) 3.88 - 3.95 (m, 1 H) 3.95 - 4.06 (m, 2 H) 4.10 - 4.26 (quadruplet, 1 H) 6.89 (s, 2 H) 6.95 -7.06 (broad d, 1 Hy:LC-MS (Method A): 451 [M+H], Rt: 1.09 min.Further elution gave the second product, 2-[(2,6-difluoro-4-pyridyl)-(tetrahydrofuran-3-carbonyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-N-(tetrahydrofuran-3-carbonyljthiazole-4-carboxamide(Compound P-1, Table 2) as a white powder.TH NMR (400 MHz, CDCls): & ppm 1.09 (s, 3 H) 1.18 (s, 3H) 1.53 - 1.66 (m, 2 H) 1.77 - 1.81 (m, 1 H)207-222(m,2H)223-234(m,1H)241-251+262-271(2xm,2H)281(s,3H)3.10- 3.26(Mm, 1H) 3.77-4.05(m, 6 H) 4.14 -4.31 + 437-443 (2 xm, 3H) 6.81 -6.92 (2xs, 2H) 7.20 (br d,J=8.44 Hz, 1 H);LC-MS (Method A): 549 [M+H], Rt: 1.15 min.Example 2: Preparation of 2-[(2,6-difluoro-4-pyridyl)-(oxetane-3-carbonylhamino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (Example P-4, Table 2)(Example P-4, Table 2)A solution of 2-[(2,6-difluoro-4-pyridyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (0.050 g, 1.0, 0.14 mmol, prepared as described in WO 2019 / 105933) in DMF (1.4 mL)was treated with oxetane-3-carboxylic acid (0.019 g, 1.2, 0.17 mmol), N,N-diisopropylethylamine (0.048g, 0.064 mL, 0.37 mmol), and HATU (0.082 g, 0.21 mmol). The resulting pale brown solution was stirredfor 4 hours at RT. After this time, the reaction mixture was quenched with saturated aqueous sodiumbicarbonate and diluted with water. It was then extracted twice with ethyl acetate and the combinedorganic layers were washed with brine, dried over anhydrous Naz2S0Oy, filtered and concentrated in vacuoto give a pale brown oil. The crude product was purified by reversed phase chromatography eluting withacetonitrile / water to give the title compound as a beige powder.TH NMR (400 MHz, CDCl) 5 ppm 0.97 (s, 3 H) 1.14 (s, 3 H) 1.50 - 1.65 (m, 2 H) 1.65 - 1.81 (m, 1 H)219-234 (m, 1H) 2.84 (s, 3 H) 3.86 - 4.01 (m, 1 H) 4.13 - 4.26 (m, 1 H) 4.51 - 4.65 (m, 2 H) 4.92 -5.06 (m, 2 H) 6.82 (s, 2 H) 6.91 - 7.08 (br s, 1 H);LC-MS (Method A): 437 [M+H], Rt: 1.05 min.Example 3: Preparation of 2-[(2,6-difluoro-4-pyridyl)-(tetrahydropyran-4-carbonyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (Example P-11, Table 2)A solution of tetrahydro-2h-pyran-4-carboxylic acid (6.282 g, 46.82 mmol) in acetonitrile (86 mL) wastreated with 1-propanephosphonic anhydride (99.32 ¢g, 93.00 mL, 156.1 mmol), N,N-diisopropylethylamine (40.75 g, 54.6 mL, 10.00, 312.1 mmol) and 2-[(2,6-difluoro-4-pyridyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide (11 g, 1.000, 31.21 mmol, prepared asdescribed in WO 2019 / 105933) were added to give a brown solution. The reaction mixture was stirredfor 16 Hr at 50°C under argon. After reaction completion, the reaction mixture was allowed to cool andslowly added to aqueous saturated sodium bicarbonate solution at 0°C. The reaction mixture wa thenextracted with ethyl acetate (x3) and the combined organic axtracts washed once with brine, dried overanhydrous NazSOq, filtered and oncentrated in vacuo to give 15.88 g of a pale brown powder. Flashchromatography eluting with an ethyl acetate / cyclohexane gave the title product as a white powder. 1HNMR (400 MHz, CDCls) & ppm 0.93 (s, 3H) 1.13 (s, 3H) 1.50 - 1.76 (m, 5 H) 1.97 - 2.09 (m, 2 H) 2.25(dtd, J=10.90, 8.08, 8.08, 2.72 Hz, 1 H) 2.60 (it, J=11.26, 3.81 Hz, 1 H) 2.81 (s, 3 H) 3.29 (it, J=11.90,1.91 Hz, 2 H) 4.01 (dt, y=11.63, 2.18 Hz, 2 H) 4.18 (q, J=8.60 Hz, 1 H) 6.89 (s, 2 H) 6.99 (br d, J=9.08Hz, 1 H)LC-MS (Method A): 465 [M+H], Rt: 1.11 min.Table 2 below illustrates exemplified individual compounds of formula (I) according to the invention.Table 2: Melting point and LC / MS data (R: = Retention time) for selected compounds of Table 1.Biological Examples:Example B1: Alternaria solani / tomato / leaf disc (early blight)Tomato leaf disks cv. Baby are placed on agar in multiwell plates (24-well format) and sprayed with theformulated test compound diluted in water. The leaf disks are inoculated with a spore suspension of thefungus 2 days after application. The inoculated leaf disks are incubated at 23 °C / 21°C (day / night) and80% rh under a light regime of 12 / 12 h (light / dark) in a climate cabinet and the activity of a compound isassessed as percent disease control compared to untreated when an appropriate level of diseasedamage appears on untreated check disk leaf disks (5 - 7 days after application). The followingcompounds gave at least 80% control of Alternaria solani at 200 ppm when compared to untreatedcontrol under the same conditions, which showed extensive disease development: P-1, P-2, P-3, P-4,P-5, P-6, P-9, P-10, and P-11.Example B2: Botryotinia fuckeliana (Botrytis cinerea) / liquid culture (Gray mould)Conidia of the fungus from cryogenic storage are directly mixed into nutrient broth (Vogels broth). Afterplacing a (DMSO) solution of test compound into a microtiter plate (96-well format), the nutrient brothcontaining the fungal spores is added. The test plates are incubated at 24 °C and the inhibition of growthis determined photometrically 3-4 days after application. The following compounds gave at least 80%control of Botryotinia fuckeliana at 20 ppm when compared to untreated control under the sameconditions, which showed extensive disease development: P-2, and P-4.Example B3: Glomerella lagenarium (Colletotrichum lagenarium) / liquid culture (Anthracnose)Conidia of the fungus from cryogenic storage are directly mixed into nutrient broth (PDB potato dextrosebroth). After placing a (DMSO) solution of test compound into a microtiter plate (86-well format), thenutrient broth containing the fungal spores is added. The test plates are incubated at 24 °C and theinhibition of growth is measured photometrically 3-4 days after application. The following compoundsgave at least 80% control of Glomerella lagenarium at 20 ppm when compared to untreated controlunder the same conditions, which showed extensive disease development: P-1, P-2, P-3, P-4, P-6, P-9, P-10, and P-11.Example B4: Blumeria graminis f. sp. tritici (Erysiphe graminis f. sp. tritici) / wheat / leaf discpreventative (Powdery mildew on wheat)Wheat leaf segments cv. Kanzler are placed on agar in a multiwell plate (24-well format) and sprayedwith the formulated test compound diluted in water. The leaf disks are inoculated by shaking powderymildew infected plants above the test plates 1 day after application. The inoculated leaf disks areincubated at 20 °C and 80% rh under a light regime of 24 h darkness followed by 12 h light / 12 hdarkness in a climate chamber and the activity of a compound is assessed as percent disease controlcompared to untreated when an appropriate level of disease damage appears on untreated check leafsegments (6 - 8 days after application). The following compounds gave at least 80% control of Blumeriagraminis f. sp. tritici at 200 ppm when compared to untreated control under the same conditions, whichshowed extensive disease development: P-1, P-2, P-3, P-4, P-5, P-6, P-7, P-8, P-9, P-10, and P-11.Example B5: Phaeosphaeria nodorum (Sepforia nodorum) / wheat / leaf disc preventative (Glumeblotch)Wheat leaf segments cv. Kanzler are placed on agar in a multiwell plate (24-well format) and sprayedwith the formulated test compound diluted in water. The leaf disks are inoculated with a sporesuspension of the fungus 2 days after application. The inoculated test leaf disks are incubated at 20 °Cand 75% rh under a light regime of 12 h light / 12 h darkness in a climate cabinet and the activity of acompound is assessed as percent disease control compared to untreated when an appropriate level ofdisease damage appears in untreated check leaf disks (5 - 7 days after application). The followingcompounds gave at least 80% control of Phaeosphaeria nodorum at 200 ppm when compared tountreated control under the same conditions, which showed extensive disease development: P-2, P-3,and P-10.Example B6: Monographella nivalis (Microdochium nivale) / liquid culture (foot rot cereals)Conidia of the fungus from cryogenic storage are directly mixed into nutrient broth (PDB potato dextrosebroth). After placing a (DMSO) solution of test compound into a microtiter plate (86-well format), thenutrient broth containing the fungal spores is added. The test plates are incubated at 24 °C and theinhibition of growth is determined photometrically 4-5 days after application. The following compoundsgave at least 80% control of Monographella nivalis at 20 ppm when compared to untreated control underthe same conditions, which showed extensive disease development: P-1, P-2, P-3, P-4, P-5, P-6, P-9,P-10, and P-11.Example B7: Mycosphaerella arachidis (Cercospora arachidicofa) / liquid culture (early leaf spot)Conidia of the fungus from cryogenic storage are directly mixed into nutrient broth (PDB potato dextrosebroth). After placing a (DMSO) solution of test compound into a microtiter plate (¢6-well format), thenutrient broth containing the fungal spores is added. The test plates are incubated at 24 °C and theinhibition of growth is determined photometrically 4-5 days after application. The following compoundsgave at least 80% control of Mycosphaerella arachidis at 20 ppm when compared to untreated controlunder the same conditions, which showed extensive disease development: P-1, P-2, and P-10.Example B8: Phakopsora pachyrhizi / soybean / preventative (soybean rust)Soybean leaf disks are placed on water agar in multiwell plates (24-well format) and sprayed with theformulated test compound diluted in water. One day after application leaf discs are inoculated byspraying a spore suspension on the lower leaf surface. After an incubation period in a climate cabinetof 24-36 hours in darkness at 20 °C and 75% rh leaf disc are kept at 20 °C with 12 h light / day and 75%rh. The activity of a compound is assessed as percent disease control compared to untreated when anappropriate level of disease damage appears in untreated check leaf disks (12 - 14 days afterapplication). The following compounds gave at least 80% control of Phakopsora pachyrhizi at 200 ppmwhen compared to untreated control under the same conditions, which showed extensive diseasedevelopment: P-2, P-3, P-4, P-6, and P-9.Example B9: Puccinia recondita f. sp. tritici / wheat / leaf disc curative (Brown rust)Wheat leaf segments cv. Kanzler are placed on agar in multiwell plates (24-well format). The leafsegments are inoculated with a spore suspension of the fungus. Plates are stored in darkness at 19 °Cand 75% rh. The formulated test compound diluted in water is applied 1 day after inoculation. The leafsegments are incubated at 19 °C and 75% rh under a light regime of 12 h light / 12 h darkness in aclimate cabinet and the activity of a compound is assessed as percent disease control compared tountreated when an appropriate level of disease damage appears in untreated check leaf segments (6 -8 days after application). The following compounds gave at least 80% control of Puccinia recondita f.sp. tritici at 200 ppm when compared to untreated control under the same conditions, which showedextensive disease development: P-1, P-2, P-3, P-4, P-5, P-6, P-9, and P-11.Example B10: Puccinia recondita f. sp. tritici / wheat / leaf disc preventative (Brown rust)Wheat leaf segments cv. Kanzler are placed on agar in multiwell plates (24-well format) and sprayedwith the formulated test compound diluted in water. The leaf disks are inoculated with a sporesuspension of the fungus 1 day after application. The inoculated leaf segments are incubated at 19 °Cand 75% rh under a light regime of 12 h light / 12 h darkness in a climate cabinet and the activity of acompound is assessed as percent disease control compared to untreated when an appropriate level ofdisease damage appears in untreated check leaf segments (7 - 9 days after application). The followingcompounds gave at least 80% control of Puccinia recondita f. sp. tritici at 200 ppm when compared tountreated control under the same conditions, which showed extensive disease development: P-1, P-2,P-3, P-4, P-5, P-6, P-7, P-9, P-10, and P-11.Example B11: Magnaporthe grisea (Pyricularia oryzae) / rice / leaf disc preventative (Rice Blast)Rice leaf segments cv. Ballila are placed on agar in a multiwell plate (24-well format) and sprayed withthe formulated test compound diluted in water. The leaf segments are inoculated with a sporesuspension of the fungus 2 days after application. The inoculated leaf segments are incubated at 22 °Cand 80% rh under a light regime of 24 h darkness followed by 12 h light / 12 h darkness in a climatecabinet and the activity of a compound is assessed as percent disease control compared to untreatedwhen an appropriate level of disease damage appears in untreated check leaf segments (5 - 7 daysafter application). The following compounds gave at least 80% control of Magnaporthe grisea at 200ppm when compared to untreated control under the same conditions, which showed extensive diseasedevelopment: P-1, P-2, P-3, P-4, P-5, P-6, P-7, P-8, P-9, and P-10.Example B12: Pyrenophora teres / barley / leaf disc preventative (Net blotch)Barley leaf segments cv. Hasso are placed on agar in a multiwell plate (24-well format) and sprayedwith the formulated test compound diluted in water. The leaf segmens are inoculated with a sporesuspension of the fungus 2 days after application. The inoculated leaf segments are incubated at 20 °Cand 65% rh under a light regime of 12 h light / 12 h darkness in a climate cabinet and the aclivity of acompound is assessed as disease control compared to untreated when an appropriate level of diseasedamage appears in untreated check leaf segments (5 - 7 days after application). The followingcompounds gave at least 80% control of Pyrenophora teres at 200 ppm when compared to untreatedcontrol under the same conditions, which showed extensive disease development. P-1, P-2, P-3, P-4,P-5, P-6, P-9, P-10, and P-11.Example B13: Sclerotinia sclerotiorum / liquid culture (cottony rot)Mycelia fragments of a newly grown liquid culture of the fungus are directly mixed into nutrient broth(PDB potato dextrose broth). After placing a (DMSO) solution of test compound into a microtiter plate(96-well format) the nutrient broth containing the fungal material is added. The test plates are incubatedat 24 °C and the inhibition of growth is determined photometrically 3-4 days after application. Thefollowing compounds gave at least 80% control of Sclerotinia sclerotiorum at 20 ppm when comparedto untreated control under the same conditions, which showed extensive disease development: P-10.Example B14 : Mycosphaerella graminicola (Septoria tritici) / liquid culture (Septoria blotch)Conidia of the fungus from cryogenic storage are directly mixed into nutrient broth (PDB potato dextrosebroth). After placing a (DMSO) solution of test compound into a microtiter plate (96-well format), thenutrient broth containing the fungal spores is added. The test plates are incubated at 24 °C and theinhibition of growth is determined photometrically 4-5 days after application. The following compoundsgave at least 80% control of Mycosphaerella graminicola at 20 ppm when compared to untreated cantrolunder the same conditions, which showed extensive disease development: P-1, P-2, P-3, P-4, P-9, P-10, and P-11.

Claims

1. A compound of Formula (I): wherein Ais C-H ar N; R1 is C1-C3alkoxyC1-C3alkyl, C1-C4alkylsulfanylC1-Csalkyl, C1-CsalkylsulfinylC1-C3alkyl, C1- C3alkylsulfonylC1-C8alkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5- or 6-membered non-aromatic monocyclic ring comprising 1, 2 or 3 heteroatoms individually selected from nitrogen, oxygen and sulfur; R1 is hydrogen or halogen; R3 is C1-Cealkyl; R1 R2, R3are each independently hydrogen or C1-C6alkyl; R7is hydrogen, C1-C6alkyl, C1-CealkoxycarbonylC1-C6alkyl, C1-C6alkoxycarbonyl, or C1-C6alkoxy:; R5 Ci- CealkylsulfinylC1-Csalkycarbonyl, C1-CsalkylsulfonylC1-Csalkycarbonyl, or heterocyclylcarbonyl, wherein is hydrogen, C1-CsalkoxyC1-Csalkycarbonyl, C1-CsalkylsulfanylC1-Csalkylcarbonyl, the heterocyclyl moiety is a 4-, 5- or 6-membered non-aromatic monocyclic ring comprising 1, 2 or 3 heteroatoms individually selected from nitrogen, oxygen and sulfur; or a salt or an N-oxide thereof.

2. The compound according to claim 1, wherein R' is C1-C6alkoxyC1-C5alkyl, C1-C5alkylsulfanylCi- Caalkyl, C1-CsalkylsulfinylC1-C3alkyl, C1-C3alkylsulfonylC4-C3alkyl, heterocyclyl moiety is a 4-, 5-, or 6-membered non-aromatic monocyclic ring comprising 1 or 2 or heterocyclyl, wherein the heteroatoms individually selected from nitrogen and oxygen.

3. The compound according to claim 1 or claim 2, wherein R1 is Cs-CsalkoxyC1-C6alkyl, C1- CsalkylsulfanylC1-C3alkyl, C1-C3alkylsulfinylC1-C6alkyl, C1-C6alkylsulfonylC1-C6alkyl, or heterocyclyl. wherein the heterocyclyl moiety is a 4-, 5-, or 6-membered non-aromatic monocyclic ring comprising 1 or 2 heteroatoms individually selected from nitrogen and oxygen.

4. The compound according to claim 1 or claim 2, wherein R' is isopropoxymethyl, tert- butoxymethyl, 1-methoxyethyl, 1-isapropoxyethyl, 1-tert-butoxyethyl, 1-methylsulfonylethyl, oxetane-3- yl, tetrahydrofuran-2-yl, tetrahydrofuran-3-yl, or tetrahydropyran-4-yl.

5. The compound according to any one of claims 1 to 3, wherein R1 is C1-C3alkylsulfanylC1-C3alkyl, C1-C3alkylsulfinylC1-C3alkyl, C1-C3alkylsulfonylC1-C3alkyl, or heterocyclyl, wherein the heterocyclyl moiety is a 4-, 5-, or 6-membered non-aromatic monocyclic ring comprising 1 or 2 heteroatoms individually selected from nitrogen and oxygen.

6. The compound according to any one of claims 1 to 3, ar claim 5, R1 is 1-methylsulfonylethyl, oxetane-3-yl, tetrahydrofuran-2-yl, tetrahydrofuran-3-yl, or tetrahydropyran-4-yl.

7. The compound according to any one of claims 1 to 6, wherein R2 is hydrogen or fluoro.

8. The compound according to any one of claims 1 to 8, wherein R3 is methyl.

9. The compound according to any one of claims 1 to 7, wherein R4 is hydrogen.

10. The compound according to any one of claims 1 to 9, wherein R5 and R6 are both methyl.

11. The compound according to any one of claims 1 to 10, wherein A is N.

12. An agrochemical composition comprising a fungicidally effective amount of a compound of formula (I) according to any one of claims 1 to 11.

13. The composition according to claim 12, further comprising at least one additional active ingredient and / or an agrochemically-acceptable diluent or carrier.

14. A method of controlling or preventing infestation of useful plants by phytopathogenic microorganisms, wherein a fungicidally effective amount of a compound of formula (I) according to any of claims 1 to 11, or a composition according to claim 12 or claim 13, is applied to the plants, to parts thereof or the locus thereof.

15. Use of a compound of formula (I) according to any one of claims 1 to 11 as a fungicide.