A herbal product consisting of at least 5 herbs: yarrow, thyme, rosemary, and oregano, based on sea salt, effective against 7 species of bacteria and one specific virus.

A herbal mixture of fennel, thyme, rosemary, oregano, and sea salt addresses the limitations of chemical treatments by creating a stable, synergistic compound effective against various bacterial and viral skin infections, ensuring efficacy and safety without chemical solvent drawbacks.

IR112647BUndetermined Publication Date: 2025-05-13ABBAS HOSSEIN POUR FALLAH
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Patent Information

Application Number
IR140250140003008759
Authority / Receiving Office
IR · IR
Patent Type
Patents
Current Assignee / Owner
Filing Date
2024-03-16
Publication Date
2025-05-13
Estimated Expiration
2044-03-16

AI Technical Summary

Technical Problem

Existing skin infection treatments, particularly for bacterial and viral infections, often rely on chemical compounds that are ineffective against multiple pathogens and cause additional health issues due to their solvent-based composition, whereas herbal alternatives are scarce and lack comprehensive efficacy against a range of infectious agents.

Method used

A herbal mixture comprising fennel, thyme, rosemary, oregano, and sea salt, using water as a solvent at 60°C to maintain the efficacy of active ingredients, which are ground and mixed with sea salt to form a stable, synergistic compound effective against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Enterococcus hirae, MRSA, E. coli, Pseudomonas aeruginosa, HSV-1, and fungi like Candida albicans.

Benefits of technology

The herbal product effectively targets multiple bacterial and viral species without harmful side effects, maintaining the integrity and synergistic potency of its components until consumption, offering a cost-effective, organic, and easy-to-use solution for skin infections.

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Abstract

Sea salt-based herbal product made from a combination of at least 5 herbs: \n1.\tArsabaran polka plant (Stachys schtschegleevii) \n2.\tPenirk plant (Malava sylvestris) \n3.\tMountain oregano plant (Mentha pulegium)\n4.\tRosemary plant (Salvia rosmarinus) or (Rosmarinus officinalis) \n5.\tShirazi or Azerbaijani thyme plant (Zataria multiflora) \nWith sea salt with antibacterial properties against 7 species of bacteria:\n1. Staphylococcus aureus ATTC 6538 bacteria\n2. Pseudomonas aeruginosa bacteria ATCC 15442 bacteria\n3. Escherichia coli ATCC 10536 bacteria\n4. Enterococcus hirae ATCC 10541 bacteria\n5. MRSA bacteria\n6. E.coli bacteria ATCC 25922\n7. Pseudomonas aeruginosa bacteria ATCC 27853\n and antiviral against 1 type of virus:\n1. HSV 1 (Herpes simplex virus 1) virus\n According to the results of official tests conducted on the antiviral and antibacterial properties of the product, we have designed and produced a medicine based on sea salt in powder form based on the medicinal properties of these plants, which has all these properties together. The main reason for its salt-based nature is the long-term durability and preservation of the product and the prevention of spoilage and contamination of the composition. Salt itself is also useful in creating a pollution-free environment. It also contributes significantly to the effectiveness of the product's properties and the effectiveness of other antiseptic benefits of this Plants are growing.
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Description

Description of the invention Title of the invention Herbal product consisting of at least 5 herbs: fennel, thyme, rosemary, and oregano, based on sea salt, effective against 7 species of bacteria and 1 specific virus species. Technical background of the relevant invention The manufactured product has medicinal uses. Technical problem and stating the objectives of the invention Various skin infections cause death or serious problems for people every day. Most of the existing methods and medicines cannot be fully effective. Most of the products available on the market for skin diseases, including fungal, viral and bacterial, are made of chemical compounds based on alcohol solvents, the use of which causes other diseases. In fact, not only can the manufactured compounds hardly fight one or two of the factors of these infections, but they themselves cause other problems due to the chemical compounds. While herbal compounds are based on harmless substances and are effective on several pathogenic factors. At the same time, they are free from undesirable effects. The purpose of this invention is to create a mixture that is based on a natural solvent and, while not causing harm, has an effect on several main agents from the bacterial family and a specific species from the viral family, and also has advantages against fungi and microbes. Here, the purpose of our product is to have an effect on several agents from these families as follows: 1. Staphylococcus aureus ATTC 6538 bacteria is one of the strongest causes of hospital infections. 2. Pseudomonas aeruginosa ATCC 15442 bacteria is a cause of hospital-acquired infections, especially in burn wound infections. 3. Escherichia coli bacteria ATCC 10536 4. Enterococcus hirae ATCC 10541 bacteria 5. MRSA bacteria are one of the strongest causes of methicillin-resistant hospital infections. 6. E. coli bacteria ATCC 25922 7. Pseudomonas aeruginosa ATCC 27853 bacteria 8. HSV 1 virus (Herpes simplex virus 1) A description of the state of the prior art and the history of developments related to the claimed invention. Due to the lack of access to the descriptions of previous inventions, we first examined the use of plants mentioned in other inventions as antibacterial and antiviral agents, then we examined other inventions that affect the microorganisms mentioned in the description of the invention. The previous inventions are listed below in order of the plants used and then the factors involved: #x200f1.#x200f#x200f Herbal antibacterial solution using hydroalcoholic extract of active ingredients of medicinal plants rhubarb root, thyme leaves and eucalyptus leaves#x200f#x200f with declaration number #x200f140050140003002653 2. Modern polymeric dressing using Shirazi thyme essential oil nanoparticles, application number 139650140003000210 3. Antibacterial, anti-inflammatory and anti-acne aftershave solution containing natural ingredients of thyme, TTO, propolis and vitamin E, declaration number 139750140003008101 #x200f4. #x200f#x200fFabrication of a drug-delivery fibrous membrane based on poly(vinylidene fluoride) containing Shirazi thyme essential oil for use in wound dressings#x200f#x200f Application No. #x200f139950140003006986 5. A skin-hydrating and repairing herbal combination containing cucumber juice, fenugreek and chicory extracts, declaration number 140050140003008898 6. Preparation and processing of herbal ointment for the treatment of surgical wounds in diabetic patients based on extracts of Panirk and Persian Golnar, application number 390020886 7. Preparation and processing of an effective herbal ointment for the treatment of surgical wounds based on the chloroform extract of Panirk, application number 390020889. #x200f8. #x200f#x200fFormulation of anti-pain, anti-inflammatory and anti-bruising cream (containing cinnamon, arnica, rosemary, lavender)#x200f#x200f with declaration number #x200f390010338 9. Ointment containing two herbal extracts of rosemary and chamomile for treating burns, declaration number 139350140003005090 10. Herbal vaginal cream containing extracts of oregano, thyme, chamomile, tea tree oil, and black seed oil for the treatment of mixed vaginal infections, application number 139850140003011127 11. Antibacterial medicine derived from medicinal plants oregano, mountain tea, bitter sage and yarrow, declaration number 139250140003001670 12. Transparent antibacterial dressings made from various biopolymers and essential oils of medicinal plants (thyme, etc.) with declaration number 13915014000306222 13. Production of recombinant nanophages against methicillin-resistant Staphylococcus aureus, application number 139650140003003619 #x200f14. #x200f#x200fFormulation of white pepper essential oil (#x200f#x200ewhite Pepper#x200e#x200f ) with fennel essential oil (#x200f#x200eFennel#x200e#x200f) and its bactericidal effect on methicillin-resistant Staphylococcus aureus (#x200f#x200eMRSA#x200e#x200f) with declaration number #x200f139550140003007819 15. Gel for healing burn wounds caused by Pseudomonas aeruginosa bacteria in a mouse model, application number 389120530 16. Combination of the montanide adjuvant ISA206 with FimH and FliC factors of uropathogenic Escherichia coli strain as a vaccine candidate against urinary tract infection in the animal phase, application number 139250140003002187 17. Truncated flagellin (FliC) from enteroaggregative Escherichia coli (EAEC) strain with immunological adjuvant, application number 139250140003009992 18. Application of Ajwain essential oil as a substitute for chemical preservatives along with growth factors on Escherichia coli bacteria, application number 390080405 19. Immunogenicity of FimH.Flic fusion protein as a vaccine candidate against urinary tract infection caused by uropathogenic Escherichia coli bacterial strain, its evaluation in an animal model, application number 13915014000308686 20. Preventive effects of ethanolic extract of Echinacea purpurea on ocular disease caused by herpes simplex type 1, application number 38607047 Providing a solution to an existing technical problem along with an accurate, sufficient, and integrated description of the invention To solve this problem, we must first find natural ingredients that each have effective and powerful ingredients against one of the aforementioned infection-causing agents. We used the following 5 plants: 1. Stachys schtschegleevii is a plant from the mint family, one of the areas where it is cultivated is Azerbaijan. It contains essential oils of alpha-pinene, beta-pinene, ocimene, limonene and myrcene, and has very high antiseptic properties and is used to treat various infectious diseases (Journal of Legal Sciences and Industries, No. 112, Volume 18, June 1402). 2. Malva sylvestris is a herbaceous plant of the Malvacea family, one of the growing areas of which is Azerbaijan. With its enamel substances, tannins, resinous substances, calcium oxalate and the effective substance of its flower, mucilage, it is mostly used in bladder problems and wound healing and anti-inflammatory (Neyshabur Journal of Medical Sciences (No. 1) Spring 2016) 3. Oregano (mentha pulegium) is a plant from the mint family that grows in Fars province and mountainous areas of Iran. With alpha-pinene... to caryophyllene oxide, it has very effective antifungal and antiviral properties, especially against Candida albicans. (Journal of Mashhad University of Dentistry, 2018, Volume 42, Issue 3, Journal of Research and Construction, Issue 82, Spring 2009) 4. Rosemary plant (Salvia rosmarinus) or (Rosmarinus officinalis) from the mint family native to the Mediterranean. It contains carosonic acid...rosmaritic acid which have antioxidant and antibacterial properties and oleanolic acid which has antiviral and antioxidant effects and .. (Iranian Plant and Biotechnology Quarterly - 1400 - Volume 16 - Issue 3 - pp. 26_13) 5. Shirazi thyme or Azerbaijani thyme (Zataria multiflora) is from the mint family. This plant is used in traditional medicine as an antiseptic, anti-inflammatory and antispasmodic. It contains substances such as thymol and caraway carol, and has antimicrobial, antibacterial, and other properties. (Journal of Food Microbiology, JFM, Year 8, Issue 4, Winter 1400, Pages 90 to 80) After selecting the herbs, we must use a preservative or base for the mixture that will prevent the effects of these ingredients on each other before consumption and keep them healthy. Here, sea salt was used for this purpose, as its disinfecting and antibacterial effects have been proven. Finally, to use the effects of the combination locally, an appropriate solvent must be used. To solve the problem of the harmfulness of alcoholic solvents, in this combination we use water at a temperature of 60 degrees, which is the optimal temperature for releasing the active ingredients of these components and has been obtained experimentally and experimentally. To produce the herbal product, first we grind 5 herbs: rosemary, oregano, parsley, thyme, and fennel, each separately with a grinding degree of 0.5 mm. Then we first mix them together, then mix and grind them again in equal proportions with a ratio of 20 to 40 percent of the herbal mixture and 40 to 60 percent sea salt. The resulting mixture is the final product. The dosage is 10 grams in 1 liter of sixty-degree water, and by observing this ratio, the product can be used in different volumes. Such as a pan or bathtub. Although the product claims that this herbal product has an effect on 7 species of bacteria and 1 species of virus, based on the documents provided in traditional medicine documents and references, each of these herbs mentioned alone has disinfectant, antifungal (such as the effect of oregano on Candida), antimicrobial, and anti-infective properties. Due to the way this herbal product is prepared, these substances remain intact until consumption and are released and exert their effect when consumed, which we only mention as advantages of this product. The plants themselves are prone to erosion due to humidity in the air and interstitial water, so coating this compound with salt prevents this from happening, so this property has been used to preserve and stabilize the materials. It was said that each component of the composition has its own active ingredients (such as rosmarinic acid, carnosic acid, tannic acid, etc.), but after dissolving in water, they form a very stable, more effective and synergistic compound together, which is one of the main reasons for choosing these specific plants. If we want to talk about the possible advantage of this product, in principle, a new molecule is not formed, but apart from the active ingredients of each component of the composition, we witness the creation of a large molecule in which tannic acid and salt play the role of high adhesion and create the desired viscosity (in addition to their antioxidant effect). This large molecule or large compound is thought to be based on water and centered on tannic acid. In addition, the predominant volume of the salt compound is, which should be explained by saying that apart from the disinfecting properties of salt, in the imagined map of this large compound, we will have abundant sodium ions at the ends of the branches, which indicates the large compound formed from the active ingredients and showing the phenolic and benzene branches that have the main effect. A clear and precise statement of the advantages of the claimed invention over prior inventions. The mentioned product, according to the technical specifications mentioned in the previous sections, has significant features such as being soluble in water, not causing harm to the consumer, being 100% organic, and easy to use, and that at the time of production, the elements were in the form of powder and separated from each other in the mixture and did not have any interaction until consumption, which improves its performance at the time of consumption, and in addition, the filler used (powdered sea salt) guarantees the shelf life and greater effectiveness of the product. None of the similar manufactured products have these features. In addition to these factors, there is the huge cost of the drugs used to repel and control these microorganisms, which either make them more resistant to antibiotics or only affect one factor or are very expensive. While the cost of producing this herbal product based on sea salt (which can be produced entirely from materials available in the country) is very low, secondly, it uses herbal and natural active ingredients, and thirdly, it affects several infectious and pathogenic agents simultaneously. Description of at least one implementation method for implementing the invention One method is to use the product at a specified dose in warm water in a container such as a bathtub and immerse (sit) the person (patient) in it for a maximum of 20 minutes, 3 times a week with one-day intervals. Explicit mention of the industrial application of the invention The field of use is medicinal use. This herbal product based on natural salt can be used in various topical ways. For example, the method suggested in the previous section is to use it as bath tablets or bath powder. However, due to the ingredients of this product, due to its ease of production and its high shelf life, it can be produced in various forms for topical use such as various creams, or even, with continued research, the product can be standardized for oral consumption. In addition, it does not have the disadvantages of drugs based on sugar preservatives or alcoholic solutions, so this combination can be used in various cases without the concerns that exist for other drugs, and even brought to the level of general use.

Claims

Claims What is claimed: Claim 1) What is claimed is a sea salt-based herbal product consisting of at least 5 specific herbs:

1. Stachys schtschegleevii 2. Malva sylvestris 3. Oregano (mentha pulegium) 4. Rosemary plant (Salvia rosmarinus) or (Rosmarinus officinalis) 5. Shirazi thyme plant (Zataria multiflora) in powder form with natural sea salt in powder form, which has antibacterial properties against 7 species of bacteria:

1. Staphylococcus aureus ATTC 6538 2. Pseudomonas aeruginosa ATCC 15442 3. Escherichia coli ATCC 10536 4. Enterococcus hirae ATCC 10541 5. MRSA 6. E. coli ATCC 25922 7. Pseudomonas aeruginosa ATCC 27853 and has antiviral properties against: HSV 1 (Herpes simplex virus 1).