Method for manufacturing the extract powder

Abstract

The purpose of this disclosure is to provide an extract powder that can improve the disintegration properties of a solid dosage form when formulated as such. [Solution] By subjecting plant and / or animal extracts to pressure shearing treatment as raw material liquids, and then spray-drying treatment, the resulting extract powder can be improved in terms of its ability to disintegrate when formulated as a solid dosage form.

Claims

1. A method for producing an extract powder, comprising: step 1, subjecting a plant and / or animal extract as a raw material to a pressure shearing treatment to obtain a pressure sheared extract; and step 2, subjecting the pressure sheared extract to a spray drying treatment to obtain an extract powder.

2. The manufacturing method according to claim 1, wherein the plant and / or animal is a Chinese medicine and / or crude drug.

3. The manufacturing method according to claim 1, wherein the Brix value of the raw material liquid is 15 to 35.

4. The manufacturing method according to claim 1, wherein the pressure conditions in step 1 are 100 to 200 MPa.

5. The manufacturing method according to claim 1, wherein in step 1, the number of times the pressurized shearing treatment is performed is 1 to 5 times.

6. The manufacturing method according to claim 1, wherein the value obtained by dividing the average particle diameter of the particles in the pressurized sheared extract by the average particle diameter of the particles in the raw material liquid is 0.05 to 0.

8.

7. The manufacturing method according to claim 1, wherein the average particle size of the particles in the pressurized sheared extract is 1 to 50 μm.

8. A step of preparing a composition for a solid dosage form using an extract powder obtained by the manufacturing method described in any one of claims 1 to 7, A method for producing a solid dosage form, comprising the step of forming the aforementioned composition for solid dosage forms into a solid dosage form.

9. A method for improving the disintegration properties of a solid dosage form containing an extract powder, A method for incorporating an extract powder obtained by a manufacturing method described in any one of claims 1 to 7 into a composition for a solid dosage form.

10. A method for improving the disintegration and hardness of tablets containing extract powder, A method for incorporating an extract powder obtained by a manufacturing method described in any one of claims 1 to 7 into a tablet composition.

11. An extract powder obtained by the manufacturing method described in any one of claims 1 to 7.

12. A solid preparation comprising the extract powder described in claim 11.

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