Water-dispersed components

Abstract

To provide a water dispersion composition obtained by dispersing a poorly soluble component represented by ceramide in water, which can be prepared by a simple method without requiring complicated operations and has high transparency and excellent dispersion stability.SOLUTION: There is provided a water dispersion composition which comprises the following components (A) to (C) in a specific ratio. (A) a lipid composition comprising the following components (A1) to (A3), (A1) a mannosylerythritol lipid represented by the following general formula (1), (A2) a phospholipid, (A3) one or two or more poorly soluble components selected from ceramides, sterols, carotenoids, tocopherols, lipoic acid and coenzyme Q10 (wherein, R1 and R2 represent a hydrogen atom or an aliphatic acyl group having 2 to 24 carbon atoms (provided that R1 and R2 do not represent a hydrogen atom at the same time), R3 and R4 represent a hydrogen atom or an acetyl group and R5 represents a hydrogen atom or an aliphatic acyl group having 2 to 24 carbon atoms.) (B) a polyhydric alcohol. (C) water.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to an aqueous dispersion composition in which a lipid composition comprising a mannosylerythritol lipid, a phospholipid and a poorly soluble component is dispersed in water.

Background Art

[0002] Poorly soluble components typified by ceramides are not soluble in water, have poor solubility in oils, and have high crystallinity. Therefore, it is generally known that it is difficult to disperse such components in water. As a method of dispersing such a poorly soluble component in water, a method of once dissolving it in an oil at a high temperature and then dispersing it in water using a surfactant is used. However, in order to obtain a highly transparent and stable aqueous dispersion composition by such a method, a large amount of surfactant is required, so there is a concern about skin irritation, and it is difficult to disperse at a high concentration. On the other hand, Patent Document 1 describes a method of dispersing a lipid dispersion composition containing a phospholipid, a ceramide and a polyhydric alcohol in an aqueous medium as a method of dispersing a large amount of ceramide stably in water. However, although the aqueous dispersion composition obtained by the method of Cited Document 1 has excellent dispersion stability, complicated operations such as high-pressure treatment using a microfluidizer or size adjustment using an extruder are required to obtain a highly transparent aqueous dispersion composition. Therefore, a method for more easily obtaining an aqueous dispersion composition having high transparency and excellent dispersion stability has been desired.

[0003] Mannosylerythritol lipid (MEL) is known as a representative glycolipid biosurfactant. It is highly biodegradable, low in toxicity, and environmentally friendly. Furthermore, it possesses physiologically active effects such as improving rough skin, anti-inflammatory and anti-allergic properties, and promoting hair growth, making it extremely useful as an active ingredient in cosmetics and topical skin preparations (see, for example, Patent Documents 2-4). Patent Document 5 describes how a composition consisting of mannosylerythritol lipid, phospholipids, and polyhydric alcohols, containing these components in specific ratios, can form MEL-containing vesicles with a particle size of 100 nm or less by a simple operation of dispersing them in water with low stirring force. However, Patent Document 5 does not describe how to disperse poorly soluble components in water. [Prior art documents] [Patent Documents]

[0004] [Patent Document 1] Japanese Patent Application Publication No. 11-130651 [Patent Document 2] International Publication No. 2007-060956 [Patent Document 3] Japanese Patent Publication No. 2005-068015 [Patent Document 4] Japanese Patent Publication No. 2003-261424 [Patent Document 5] Japanese Patent Publication No. 2018-024639 [Overview of the Initiative] [Problems that the invention aims to solve]

[0005] The object of the present invention is to provide an aqueous dispersion composition in which poorly soluble components, such as ceramides, are dispersed in water, which can be prepared by a simple method that does not require complicated operations, and which has high transparency and excellent dispersion stability. [Means for solving the problem]

[0006] The inventors of this invention conducted extensive research to solve the above problems and, as a result, discovered that an aqueous dispersion composition containing the following components (A) to (C) in specific ratios can solve the above problems, thus completing the present invention. (A) Lipid composition consisting of the following components (A1) to (A3) (A1) Mannosylerythritol lipid represented by the following general formula (1) [ka] (In the formula, R1 and R2 represent hydrogen or an aliphatic acyl group having 2 to 24 carbon atoms (but not both containing hydrogen). Also, R3 and R4 represent hydrogen or an acetyl group, and R5 represents hydrogen or an aliphatic acyl group having 2 to 24 carbon atoms.) (A2) Phospholipids (A3) One or more poorly soluble components selected from ceramides, sterols, carotenoids, tocopherols, lipoic acid, and coenzyme Q10. (B) Polyhydric alcohols (C)Water [Effects of the Invention]

[0007] The aqueous dispersion composition of the present invention can be prepared by a simple method, and the resulting aqueous dispersion composition has high transparency and excellent dispersion stability. [Modes for carrying out the invention]

[0008] The aqueous dispersion composition of the present invention is characterized by containing the following components (A) to (C). (A) Lipid composition consisting of the following components (A1) to (A3) (A1) Mannosylerythritol lipid represented by the following general formula (1) [ka] (In the formula, R1 and R2 represent hydrogen or an aliphatic acyl group having 2 to 24 carbon atoms (but not both containing hydrogen). Also, R3 and R4 represent hydrogen or an acetyl group, and R5 represents hydrogen or an aliphatic acyl group having 2 to 24 carbon atoms.) (A2) Phospholipids (A3) One or more poorly soluble components selected from ceramides, sterols, carotenoids, tocopherols, lipoic acid, and coenzyme Q10. (B) Polyhydric alcohols (C)Water

[0009] The mannosylerythritol lipid (A1) used in the present invention is a compound represented by the general formula (1) above. However, the mannosylerythritol lipid of general formula (1) encompasses various compounds depending on the bonding position of the acyl and acetyl groups, and four types, MEL-A, MEL-B, MEL-C, and MEL-D, are generally widely known. MEL-A is a compound in which R1 and R2 of general formula (1) are acyl groups, R3 and R4 are acetyl groups, and R5 is hydrogen. MEL-B is a compound in which R1 and R2 of general formula (1) are acyl groups, R3 is hydrogen, R4 is an acetyl group, and R5 is hydrogen. MEL-C is a compound in which R1 and R2 of general formula (1) are acyl groups, R3 is an acetyl group, R4 is hydrogen, and R5 is hydrogen. MEL-D is a compound in which R1 and R2 of general formula (1) are acyl groups, R3 and R4 are hydrogen, and R5 is hydrogen. Any of these can be used in the present invention, but MEL-B or MEL-C are preferred in terms of availability and better demonstrating the effects of the invention, with MEL-B being the most preferred. Furthermore, R1, R2, and R5 of general formula (1) are preferably saturated or unsaturated acyl groups having 6 to 20 carbon atoms. There are no particular restrictions on the method for producing mannosylerythritol lipid, and it can be produced by known methods. Generally, fermentation methods using microorganisms are known, and for example, it can be produced by the method described in Japanese Patent Application Publication No. 2009-275017.

[0010] Examples of phospholipids used in the present invention as component (A2) include diacylglycerophospholipids having polar groups such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, and phosphatidic acid; natural lecithin obtained from plants such as soybeans, rapeseed, sunflower, safflower, peanuts, cottonseed, corn, rice, and barley, as well as egg yolks, and their hydrogenated derivatives. Furthermore, these may also be derivatives modified with polyoxyalkylene groups such as polyethylene glycol. These phospholipids may be used individually or in mixtures of two or more types. Of these, natural lecithin and its hydrogenated derivatives are preferred from the viewpoint of availability and better demonstrating the effects of the present invention. As for natural lecithin, commercially available types have varying phosphatidylcholine (hereinafter referred to as PC) content depending on the degree of purification, but for the present invention, it is preferable to use one with a PC content of 30% by mass or more, more preferably 40% by mass or more, and most preferably 50% by mass or more.

[0011] Component (A3) used in the present invention is one or more poorly soluble components selected from ceramides, sterols, carotenoids, tocopherols, lipoic acid, and coenzyme Q10. All of these are components known to exhibit excellent effects on the skin or hair. More specifically, examples of ceramides include ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6, ceramide 7, sphingosine, phytosphingosine, etc. Among these, ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6, and ceramide 7 are more preferable. Examples of sterols include cholesterol, dihydrocholesterol, lanosterol, dihydrolanosterol, desmosterol, stigmasterol, sitosterol, campesterol, brassicasterol, phytosterol, ergosterol, oryzanol, etc. Among these, cholesterol, phytosterol, and oryzanol are more preferable. Examples of carotenoids include carotene, lycopene, cryptoxanthin, lutein, zeaxanthin, astaxanthin, crocetin, fucoxanthin, etc. Among these, lutein and astaxanthin are more preferable. Examples of tocopherols include α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, α-tocotrienol, β-tocotrienol, γ-tocotrienol, δ-tocotrienol, tocopherol acetate, tocopherol nicotinate, etc. Among these, α-tocopherol, β-tocopherol, γ-tocopherol, and δ-tocopherol are more preferable.

[0012] In the present invention, the mass ratio of components (A1) and (A2) is 8:2 to 1:9. When the mass ratio of components (A1) and (A2) is outside this range, the effects of the present invention, such as high transparency and excellent dispersion stability, are not fully achieved. From the perspective of more effectively exerting the effects of the present invention, the mass ratio of components (A1) and (A2) is more preferably 6.5:3.5 to 1:9, further preferably 5.5:4.5 to 1.5:8.5, and most preferably 5:5 to 2:8.

[0013] In the present invention, the content of component (A3) in component (A) is 1 to 36% by mass. Even if the content of component (A3) is less than 1% by mass, the effects of the present invention can still be achieved, but the concentration of component (A3) in the aqueous dispersion composition will be low, which is undesirable in that it will not fully exert the efficacy and effects of component (A3). From this viewpoint, the content of component (A3) is more preferably 5% by mass or more, and even more preferably 10% by mass or more. Furthermore, if the content of component (A3) is more than 36% by mass, the effects of the present invention, such as high transparency and excellent dispersion stability, will not be fully achieved. From the viewpoint of further exerting the effects of the present invention, the content of component (A3) is more preferably 34% by mass or less, and even more preferably 32% by mass or less.

[0014] In the present invention, component (A) can be included in the aqueous dispersion composition to the extent that the effects of the present invention are not impaired, and there are no particular restrictions on its content, but it is usually 0.1 to 15% by mass. From the viewpoint of further exhibiting the efficacy and effects of component (A), 0.5% by mass or more is more preferable, and 1% by mass or more is even more preferable. Furthermore, from the viewpoint of further exhibiting the effects of the present invention, 12% by mass or less is more preferable, and 10% by mass or less is even more preferable.

[0015] Examples of the polyhydric alcohol as the component (B) used in the present invention include dihydric alcohols such as ethylene glycol, propylene glycol, 1,3 - propanediol, 1,2 - butylene glycol, 1,3 - butylene glycol, 2,3 - butylene glycol, tetramethylene glycol, hexylene glycol, octylene glycol, 1,2 - pentanediol, 1,2 - hexanediol, 1,2 - heptanediol, 1,2 - octanediol, 1,2 - decanediol, etc.; trihydric alcohols such as glycerin, trimethylolpropane, 1,2,6 - hexanetriol, etc.; sugar alcohols such as sorbitol, xylitol, erythritol, maltitol, mannitol, etc.; glyceryl ethers such as ethyl glycerin, butyl glycerin, hexyl glycerin, ethylhexyl glycerin, etc.; polyhydric alcohol polymers such as diethylene glycol, triethylene glycol, tetraethylene glycol, polyethylene glycol, dipropylene glycol, tripropylene glycol, polypropylene glycol, diglycerin, triglycerin, tetraglycerin, polyglycerin, etc. These may be used alone or in combination of two or more. Among these, glycerin, propylene glycol, 1,3 - propanediol, dipropylene glycol, 1,3 - butylene glycol, 1,2 - pentanediol, 1,2 - hexanediol, 1,2 - heptanediol, 1,2 - octanediol are preferred, and 1,3 - butylene glycol, glycerin, 1,2 - pentanediol, 1,2 - hexanediol are most preferred.

[0016] The water as the component (C) used in the present invention is not particularly limited as long as it can be used in ordinary cosmetics, and purified water, ion - exchanged water, distilled water, natural water, deep - sea water, hydrogen water, etc. can be used. Further, it may be one whose pH is adjusted with an acid, an alkali, a buffer, a chelating agent, etc., or one to which water - soluble components such as a preservative are added.

[0017] The aqueous dispersion composition of the present invention is a dispersion of component (A) in water, and it is preferable that component (A) forms a lipid membrane structure. A lipid membrane structure refers to vesicles, bicelles, etc. It is believed that by forming such a structure, the precipitation of highly crystalline, poorly soluble components is suppressed, and the effects of the present invention, such as excellent dispersion stability, are achieved.

[0018] The aqueous dispersion composition of the present invention is a dispersion of component (A) in water. However, each component constituting component (A) is in solid form, making it difficult to disperse component (A) directly in water. Therefore, in the present invention, the polyhydric alcohol component (B) is used for the purpose of dispersing component (A) in water. That is, the aqueous dispersion composition of the present invention can be prepared by first preparing a polyhydric alcohol solution by stirring and mixing component (A) and component (B) while heating, and then adding water to the obtained polyhydric alcohol solution while stirring, or by adding the polyhydric alcohol solution to water while stirring. Surprisingly, the aqueous dispersion composition of the present invention, prepared by such a simple method, can be obtained as a highly transparent product without the need for complicated operations such as high-pressure treatment with a microfluidizer or particle sizing with an extruder. In preparing the aqueous dispersion composition of the present invention, component (B) should be used in an amount of 2 times or more by mass relative to component (A), and more preferably 2.5 times or more by mass. If the content of component (B) is less than this, component (A) cannot be sufficiently dispersed in component (B), and the effects of the present invention will not be fully realized.

[0019] In the aqueous dispersion composition of the present invention, high transparency means that when the sample is placed in a 3.5 cm diameter glass bottle and observed from the side, the liquid is transparent enough that the area behind it can be seen through. When measuring turbidity with a spectrophotometer, the transmittance is 60% or higher when the sample is placed in a 1 cm thick cell and measured at a wavelength of 600 nm.

[0020] The aqueous dispersion composition of the present invention can be used as is as a cosmetic, or it can be used as a cosmetic ingredient by being incorporated during the manufacture of cosmetics. When the aqueous dispersion composition of the present invention is used as a cosmetic ingredient, there are no particular restrictions on the amount to be incorporated, but it is generally 0.01 to 99% by mass, preferably 0.05 to 90% by mass.

[0021] The cosmetic composition of the present invention may optionally contain water and additives commonly used in cosmetics, such as oily bases, moisturizers / texture enhancers, surfactants, polymers / thickeners / gelling agents, antioxidants, reducing agents, oxidizing agents, antioxidants, whitening agents, vitamins and their derivatives, plant / animal / microbial extracts, UV absorbers, antibacterial / preservatives, chelating agents, pH adjusters / acids / alkalis, solvents / propellants, antipruritics, exfoliating / dissolving agents, antiperspirants, cooling agents, astringents, enzymes, nucleic acids, anti-inflammatory agents, hair growth agents / blood circulation promoters / stimulants, hormones, anti-wrinkle / anti-aging agents, irritation relievers, cooling agents, warming agents, powders, pigments / colorants / dyes / pigments, fragrances, etc., in amounts that do not impair the effects of the present invention.

[0022] As oily bases, higher alcohols such as cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, arachidodecanol, behenyl alcohol, jojoba alcohol, chymyl alcohol, cerachidodecanol, batyl alcohol, hexyldecanol, isostearyl alcohol, 2-octyldodecanol, dimergol, etc.; aralkyl alcohols and derivatives such as benzyl alcohol; lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, Undecylenic acid, 12-hydroxystearic acid, palmitoleic acid, oleic acid, linoleic acid, linolenic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexadecanoic acid, anteisohenicosanoic acid, long-chain branched fatty acids, long-chain α-hydroxy fatty acids, dimer acids, hydrogenated dimer acids, and other higher fatty acids, as well as metal soaps such as aluminum salts, calcium salts, magnesium salts, zinc salts, potassium salts, and sodium salts thereof, and nitrogen-containing derivatives such as amides; liquid paraffin (mineral oil), heavy liquid isoparaffin, light liquid isoparaffin Hydrocarbons such as α-olefin oligomers, polyisobutene, hydrogenated polyisobutene, polybutene, squalane, olive-derived squalane, squalene, petrolatum, and solid paraffin; waxes such as candelilla wax, carnauba wax, rice wax, wood wax, beeswax, montan wax, ozokerite, ceresin, paraffin wax, microcrystalline wax, petrolatum, Fischer-Tropsch wax, polyethylene wax, and ethylene-propylene copolymer; coconut oil, palm oil, palm kernel oil, safflower oil, and olive oil. Vegetable oils such as castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut oil, hazelnut oil, kukui nut oil, rosehip oil, meadowfoam oil, peach kernel oil, tea tree oil, peppermint oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, rice bran oil, cocoa butter, shea butter, hydrogenated coconut oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil, etc.; animal fats such as beef tallow, milk fat, horse fat, egg yolk oil, mink oil, turtle oil, etc.; animal waxes such as whale wax, lanolin, orange roughy oil, etc.Lanolins such as liquid lanolin, reduced lanolin, adsorbed and purified lanolin, lanolin acetate, liquid lanolin acetate, hydroxylanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol, lanolin acetate alcohol, and (cetyl lanolyl) acetate; lecithin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, and sphingomyelin; Phospholipids such as gophospholipids, phosphatidic acid, cyclic lysophosphatidic acid or its salts, and lysolecithin; phospholipid derivatives such as hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid, hydrogenated egg yolk phospholipid, and partially hydrogenated egg yolk phospholipid; sterols such as cholesterol, dihydrocholesterol, lanosterol, dihydrolanosterol, phytosterol, and cholic acid; sapogenins; saponins; cholesteryl acetate, cholesteryl nonanoate, cholesteryl stearate, Cholesteryl isostearate, cholesteryl oleate, N-lauroyl-L-glutamic acid di(cholesteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamic acid di(cholesteryl / octyldodecyl), N-lauroyl-L-glutamic acid di(phytosteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamic acid di(phytosteryl / octyldodecyl), N-lauroyl sarcosinate isopropyl, etc. Acyl sarcosinate alkyl Sterol esters such as cholesteryl 12-hydroxystearate, cholesteryl macadamia nut oil fatty acid, phytosteryl macadamia nut oil fatty acid, phytosteryl sunflower seed oil fatty acid, phytosteryl isostearate, cholesteryl soft lanolin fatty acid, cholesteryl hard lanolin fatty acid, long-chain branched fatty acid cholesteryl, long-chain α-hydroxy fatty acid cholesteryl; lipid complexes such as phospholipid-cholesterol complexes and phospholipid-phytosterol complexes;Octyldodecyl myristate, hexyldecyl myristate, octyldodecyl isostearate, cetyl palimitate, octyldodecyl palmitate, cetyl octanoate, hexyldecyl octanoate, isotridecyl isononanoate, isononyl isononanoate, octyl isononanoate, isotridecyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, isostearyl neopentanoate, octyldodecyl neodecanoate, oleyl oleate, octyldodecyl oleate, octyldodecyl ricinoleate, octyldodecyl lanolate, dicaprylyl carbonate, hexyldecyl dimethyloctanoate, octyldodecyl erucate, hydrogenated castor oil isostearate, Monoalcoholic carboxylic acid esters such as ethyl oleate, ethyl avocado oil fatty acid, isopropyl myristate, isopropyl palmitate, octyl palmitate, isopropyl isostearate, isopropyl lanolinate, methylheptyl laurate, methylheptyl myristate, methylheptyl palmitate, methylheptyl isostearate, diethyl sebacate, diisopropyl sebacate, dioctyl sebacate, diisopropyl adipate, dibutyloctyl sebacate, diisobutyl adipate, dioctyl succinate, triethyl citrate, etc.; oxyacid esters such as cetyl lactate, hydrogenated castor oil monoisostearate, γ-erucalactone, diisostearyl malate;Glyceryl trioctanoate, glyceryl trioleate, glyceryl triisostearate, glyceryl diisostearate, caprylic / capric triglyceride, caprylic / capric / myristic / stearic triglyceride, hydrogenated rosin triglyceride (hydrogenated ester gum), rosin triglyceride (ester gum), glyceryl eicosanedioate behenate, trimethylolpropane trioctanoate, trimethylolpropane triisostearate, neopentyl glycol dioctanoate, dicaprylic trioctanoate Neopentyl glycol dioctanoate, 2-butyl-2-ethyl-1,3-propanediol dioctanoate, propylene glycol dioleate, pentaerythrityl tetraoctanoate, hydrogenated rosin pentaerythrityl, ditrimethylolpropane triethylhexanoate, ditrimethylolpropane (isostearate / sebacate), pentaerythrityl triethylhexanoate, dipentaerythrityl (hydroxystearate / stearate / rosinate), diglyceryl diisostearate, polyglyceryl tetraisostearate Polyglyceryl-10 nonaisostearate, polyglyceryl-8 deca(erucic acid / isostearate / ricinoleic acid), diglyceryl oligoester (hexyldecanoic acid / sebacic acid), glycol distearate (ethylene glycol distearate), polyhydric alcohol fatty acid esters such as 3-methyl-1,5-pentanediol dieopentanoate and 2,4-diethyl-1,5-pentanediol dieopentanoate; alkyl ethers such as dicaprylyl ether; diisopropyl dimer dilinoleate, dima Dimer acids or dimer ol derivatives such as diisostearyl dilinoleate, di(isostearyl / phytosteryl) dimer dilinoleate, (phytosteryl / behenyl) dimer dilinoleate, (phytosteryl / isostearyl / cetyl / stearyl / behenyl) dimer dilinoleate, dimer dilinoleyl diisostearate, hydrogenated rosin condensate of dimer dilinoleate, hydrogenated castor oil of dimer dilinoleate, and hydroxyalkyl dimer dilinoleyl ether;Fatty acid alkanolamides such as coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (palmitamide MEA), palmitic acid diethanolamide (palmitamide DEA), coconut oil fatty acid methylethanolamide (cocamide methyl MEA); dimethicone (dimethylpolysiloxane), highly polymerized dimethicone (highly polymerized dimethylpolysiloxane), cyclomethicone (cyclic dimethylsiloxane, decamethylcyclopentasiloxane), phenyl trimethicone, diphenyl dimethicone, phenyl dimethicone, (aminoethylaminopropyl methicone / dimethicone) copolymer, dimethiconol, dimethiconol crosspolymer, silicone resin, silicone Silicones such as corn rubber, amino-modified silicones like aminopropyl dimethicone and amodimethicone, cationic-modified silicones, polyether-modified silicones like dimethicone copolyol, polyglycerin-modified silicones, sugar-modified silicones, carboxylic acid-modified silicones, phosphate-modified silicones, sulfuric acid-modified silicones, alkyl-modified silicones, fatty acid-modified silicones, alkyl ether-modified silicones, amino acid-modified silicones, peptide-modified silicones, fluorine-modified silicones, cationic-modified and polyether-modified silicones, amino-modified and polyether-modified silicones, alkyl-modified and polyether-modified silicones, amide-alkyl-modified silicones, amino glycol-modified silicones, aminophenyl-modified silicones, and polysiloxane-oxyalkylene copolymers are preferred; fluorine-based oils such as perfluorodecane, perfluorooctane, and perfluoropolyether are also preferred.

[0023] As moisturizers and texture enhancers, polyols and their polymers such as glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, trimethylolpropane, pentaerythritol, hexylene glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, and ethylene glycol / propylene glycol copolymers; glycol alkyl ethers such as diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, and diethylene glycol dibutyl ether; water-soluble esters such as (eicosanedioic acid / tetradecanedioic acid) polyglyceryl-10, tetradecanedioic acid polyglyceryl-10, and cyclohexanedicarboxylic acid bisethoxydiglycol; and sugars such as sorbitol, xylitol, erythritol, mannitol, and maltitol. Glucolic compounds; glucose, fructose, galactose, mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose, raffinose, gluconic acid, glucuronic acid, cyclodextrins (α-, β-, γ-cyclodextrins, and modified cyclodextrins such as maltosylation and hydroxyalkylation), β-glucan, chitin, chitosan, heparin and derivatives, pectin, arabinogalactan, dextrin, dextran, glycan Sugars and their derivatives such as cogen, ethyl glucoside, glucosylethyl methacrylate polymer or copolymer; hyaluronic acid, sodium hyaluronate; sodium chondroitin sulfate; mucoitin sulfate, caronin sulfate, kerato sulfate, dermatan sulfate; Tremella fuciformis extract, Tremella fuciformis polysaccharide; fructans such as inulin and levan; fucoidan; tuberose polysaccharide, naturally derived polysaccharide; organic acids such as citric acid, tartaric acid, lactic acid and their salts; urea; 2-pyrrolidone-5-carboxylic acid and its sodium salts;Amino acids and their salts such as betaine (trimethylglycine), proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β-alanine, threonine, glutamic acid, glutamine, asparagine, aspartic acid, cysteine, cystine, methionine, leucine, isoleucine, valine, tryptophan, histidine, taurine, γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid, carnitine, carnosine, creatine, collagen, fish collagen, atelocollagen, gelatin, elastin, collagen-degraded peptides, hydrolyzed collagen, hydroxypropylammonium chloride hydrolyzed collagen, elastin-degraded peptides, keratin-degraded peptides, hydrolyzed keratin, conchiolin-degraded peptides, hydrolyzed conchiolin, silk protein-degraded peptides, hydrolyzed silk, sodium lauroyl hydrolyzed silk, soy protein-degraded peptides, small Protein peptides and their derivatives such as wheat proteolytic peptides, hydrolyzed wheat protein, casein proteolytic peptides, and acylated peptides; acylated peptides such as palmitoyl oligopeptides, palmitoyl pentapeptides, and palmitoyl tetrapeptides; silylated peptides; lactic acid bacteria culture solution, yeast extract, eggshell membrane protein, bovine submandibular gland mucin, hypotaurine, sesame lignan glycosides, glutathione, albumin, whey; choline chloride, phosphorylcholine; placental extract, air Preferred ingredients include animal and plant extracts such as rustin, collagen, aloe extract, witch hazel water, loofah water, chamomile extract, licorice extract, comfrey extract, silk extract, rose extract, yarrow extract, eucalyptus extract, and sweet clover extract; and ceramides such as natural ceramides (types 1, 2, 3, 4, 5, and 6), hydroxyceramides, pseudoceramides, sphingoglycolipids, and ceramide and glycoceramide-containing extracts.

[0024] Preferred surfactants include anionic surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants, and polymeric surfactants. There are no particular restrictions on the HLB of surfactants; those with a low HLB of around 1 to a high HLB of around 20 can be used, and combinations of low and high HLB surfactants are also preferred. Examples of preferred surfactants include, among anionic surfactants, fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfate esters such as sodium lauryl sulfate, triethanolamine lauryl sulfate, and ammonium lauryl sulfate; polyoxyethylene alkyl sulfates such as sodium laureth sulfate and triethanolamine laureth sulfate; acyl N-methyl amino acid salts such as sodium cocoyl methyl taurate, potassium cocoyl methyl taurate, sodium lauroyl methyl taurate, sodium myristoyl methyl taurate, sodium lauroyl methylalanine, sodium lauroyl sarcosinate, triethanolamine lauroyl sarcosinate, and sodium lauroyl glutamate methylalanine; and sodium cocoyl glutamate, triethanolamine cocoyl glutamate, and sodium lauroyl glutamate. Acyl amino acid salts such as sodium myristoyl glutamate, sodium stearoyl glutamate, palmitoyl aspartate ditriethanolamine, cocoyl alanine triethanolamine, sodium dilauroyl glutamate lysine; polyoxyethylene alkyl ether acetates such as sodium laureth acetate; succinate esters such as sodium lauroyl monoethanolamide succinate; fatty acid alkanolamide ether carboxylates; acyl lactates; polyoxyethylene fatty acid amine sulfates; fatty acid alkanolamide sulfates; fatty acid glyceride sulfates such as hydrogenated coconut oil fatty acid glycerin sulfate sodium; alkylbenzene polyoxyethylene sulfates; olefin sulfonates such as sodium α-olefin sulfonate; alkyl sulfosuccinates such as disodium lauryl sulfosuccinate and sodium dioctyl sulfosuccinate;Alkyl ether sulfosuccinates such as disodium laureth sulfosuccinate, sodium monolauroyl monoethanolamide polyoxyethylene sulfosuccinate, sodium lauryl polypropylene glycol sulfosuccinate; alkylbenzene sulfonates such as sodium tetradecylbenzenesulfonate, triethanolamine tetradecylbenzenesulfonate; alkylnaphthalene sulfonates; alkane sulfonates; α-sulfo fatty acid methyl ester salts; acyl isethionates; alkyl glycidyl ether sulfonates; alkyl sulfoacetates; alkyl ether phosphate salts such as sodium laureth phosphate, sodium dilaureth phosphate, sodium trilaureth phosphate, sodium monooleth phosphate; alkyl phosphate salts such as potassium lauryl phosphate; sodium caseinate; alkylaryl ether phosphates; fatty acid amide ether phosphates; phospholipids such as phosphatidylglycerol, phosphatidylinositol, phosphatidic acid, cyclic lysophosphatidic acid or their salts; carboxylic acid-modified silicones, phosphate-modified silicones, sulfuric acid-modified silicones, etc. Lycorn-based anionic surfactants, etc.; nonionic surfactants include various polyoxyethylene alkyl ethers with different polyoxyethylene addition numbers, such as laureth (polyoxyethylene lauryl ether), ceteth (polyoxyethylene cetyl ether), steareth (polyoxyethylene stearyl ether), beheneth (polyoxyethylene behenyl ether), isosteareth (polyoxyethylene isostearyl ether), octyldodeceth (polyoxyethylene octyldodecyl ether), etc.; polyoxyethylene alkylphenyl ethers Castor oil and hydrogenated castor oil derivatives such as polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, polyoxyethylene hydrogenated castor oil monopyloglutamic acid monoisostearate diester, polyoxyethylene hydrogenated castor oil maleic acid; polyoxyethylene phytosterol; polyoxyethylene cholesterol; polyoxyethylene cholesterol; polyoxyethylene cholestanol; polyoxyethylene lanolin; polyoxyethylene reduced lanolin;Polyoxyethylene / polyoxypropylene alkyl ethers such as polyoxyethylene / polyoxypropylene cetyl ether, polyoxyethylene / polyoxypropylene 2-decyltetradecyl ether, polyoxyethylene / polyoxypropylene monobutyl ether, polyoxyethylene / polyoxypropylene hydrogenated lanolin, polyoxyethylene / polyoxypropylene glycerin ether; polyoxyethylene / polyoxypropylene glycol; (poly) such as PPG-9 diglyceryl. ) Glycerin polyoxypropylene glycol; glyceryl stearate, glyceryl isostearate, glyceryl palmitate, glyceryl myristate, glyceryl oleate, coconut oil fatty acid glyceryl, monocottonseed oil fatty acid glycerin, monoerucate glycerin, sesquioleate glycerin, α,α'-oleate pyroglutamate glycerin, monostearate glycerin malic acid and other glycerin fatty acid partial esters; polyglyceryl-2, 3, 4, 5, 6, 8 stearate , same 10, polyglyceryl-6 distearate, same 10, polyglyceryl-2 tristearate, polyglyceryl-10 decaisostearate, polyglyceryl-2 isostearate, same 3, same 4, same 5, same 6, same 8, same 10, polyglyceryl-2 diisostearate (diglyceryl diisostearate), same 3, same 10, polyglyceryl-2 triisostearate, polyglyceryl-2 tetraisostearate, polyglyceryl-10 decaisostearate, polyglyceryl-2 oleate, same 3, Polyglycerin fatty acid esters such as Polyglyceryl-6 dioleate, Polyglyceryl-2 trioleate, Polyglyceryl-10 decaoleate; Ethylene glycol monofatty acid esters such as Ethylene glycol monostearate; Propylene glycol monofatty acid esters such as Propylene glycol monostearate; Pentaerythritol partial fatty acid ester; Sorbitol partial fatty acid ester; Maltitol partial fatty acid ester; Maltitol ether;Sorbitan fatty acid esters such as sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, sorbitan penta-2-ethylhexyl diglycerol sorbitan, sorbitan tetra-2-ethylhexyl diglycerol sorbitan; sucrose fatty acid esters such as sucrose laurate, sucrose myristate, sucrose palmitate, sucrose dilaurate, sucrose dimyristate, sucrose dipalmitate. Partial esters of sugar derivatives such as methyl glucoside fatty acid esters and undecylenate trehalose; alkyl glucosides such as caprylyl glucoside; alkyl polyglycosides; glycolipids such as mannosyl erythritol lipid; lanolin alcohol; reduced lanolin; polyoxyethylene fatty acid mono and diesters such as polyoxyethylene distearate, polyethylene glycol diisostearate, polyoxyethylene monooleate, and polyoxyethylene dioleate; polyoxyethylene propylene glycol fatty acid esters; polyoxyethylene glycol Polyoxyethylene glycerin fatty acid esters such as serine monostearate, polyoxyethylene glycerin monoisostearate, polyoxyethylene glycerin triisostearate, and other polyoxyethylene monooleates; polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan tetraoleate; polyoxyethylene sorbitol fatty acid esters such as polyoxyethylene sorbitol monolaurate, polyoxyethylene sorbitol monooleate, polyoxyethylene sorbitol pentaoleate, and polyoxyethylene sorbitol monostearate; polyoxyethylene methyl glucoside fatty acid esters; polyoxyethylene alkyl ether fatty acid esters; polyoxyethylene animal and vegetable oils and fats such as polyoxyethylene sorbitol beeswax; alkyl glyceryl ethers such as isostearyl glyceryl ether, chymyl alcohol, cerakyl alcohol, and batyl alcohol; polyhydric alcohol alkyl ethers;Polyoxyethylene alkylamines; tetrapolyoxyethylene-tetrapolyoxypropylene-ethylenediamine condensates; natural surfactants such as saponins, surfactin, rhamnolipids, and sophorolipids; polyoxyethylene fatty acid amides; coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid Fatty acid alkanolamides such as palmitate monoethanolamide (paltamide MEA), palmitate diethanolamide (paltamide DEA), and coconut oil fatty acid methylethanolamide (cocamide methyl MEA); alkyldimethylamine oxides such as lauramine oxide, cocamine oxide, stearamine oxide, and behenamine oxide; alkylethoxydimethylamine oxide; polyoxyethylene alkyl mercaptan; polyether-modified silicones such as dimethicone copolyol, polysiloxane-oxyalkylene copolymers, and polyglycerin-modified silicones. Silicone-based nonionic surfactants such as silicones and sugar-modified silicones; cationic surfactants include alkyltrimethylammonium chlorides such as behentrimonium chloride, steartrimonium chloride, cetrimonium chloride, and lauryltrimonium chloride; alkyltrimethylammonium bromides such as stearyltrimonium bromide; dialkyldimethylammonium chlorides such as distearyldimonium chloride and dicocodimonium chloride; fatty acid amide amines and their salts such as stearamidopropyldimethylamine and stearamidoethyldiethylamine; alkyl etheramines and their salts or quaternary salts such as stearoxypropyldimethylamine; fatty acid amide-type quaternary ammonium salts such as ethyl sulfate long-chain branched fatty acid (12-31) aminopropylethyldimethylammonium and ethyl sulfate lanolin fatty acid aminopropylethyldimethylammonium; polyoxyethylene alkylamines and their salts or quaternary salts; alkylamine salts; fatty acid amide guanidium salts; alkyl etheramine mononium salts; alkyltrial chloroglycol ammonium salts; benzalkonium salts;Benzethonium salts; pyridinium salts such as cetylpyridinium chloride; imidazolinium salts; alkylisoquinolinium salts; dialkylmolyphonium salts; polyamine fatty acid derivatives; silicone-based cationic surfactants such as aminopropyl dimethicone and amodimethicone (amino-modified silicones), cationic-modified silicones, cationic and polyether-modified silicones, amino-modified and polyether-modified silicones; amphoteric surfactants such as N-alkyl-N,N-dimethylamino acid betaines such as lauryl betaine (lauryldimethylaminoacetic acid betaine); fatty acid amide alkyl-N,N-dimethylamino acid betaines such as cocamidopropyl betaine and lauramidopropyl betaine; imidazoline-type betaines such as sodium cocoamphoacetate and sodium lauroamphoacetate; Preferred surfactants include: alkyl sulfobetaines such as alkyldimethyl taurine; sulfate-type betaines such as alkyldimethylaminoethanol sulfate; phosphate-type betaines such as alkyldimethylaminoethanol phosphate; sphingophospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and sphingomyelin; phospholipids such as lysolecithin, hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid, hydrogenated egg yolk phospholipid, partially hydrogenated egg yolk phospholipid, and hydroxylated lecithin; silicone-based amphoteric surfactants, etc.; polymeric surfactants include polyvinyl alcohol, sodium alginate, starch derivatives, tragacanth gum, acrylic acid / alkyl methacrylate copolymer; and various silicone-based surfactants.

[0025] Examples of polymers, thickeners, and gelling agents include guar gum, locust bean gum, queen seed gum, carrageenan, galactan, gum arabic, tara gum, tamarind, fercerelan, karaya gum, okra gum, tragacanth gum, pectin, pectic acid and its salts, alginic acid and its salts, mannan; starches from rice, corn, potato, wheat, etc.; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salts, xanthan gum, pullulan, gellan gum, chitin, chitosa Agar, cassia seed extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose and its sodium salts, methylhydroxypropylcellulose, carboxylated cellulose nanofiber, carboxymethylated cellulose nanofiber, phosphate-esterified cellulose nanofiber, sulfonated cellulose nanofiber, sodium cellulose sulfate, dialkyldimethylammonium sulfur Cellulose and its derivatives such as cellulose acid, crystalline cellulose, and cellulose powder; starch-based polymers such as soluble starch, carboxymethyl starch, methylhydroxypropyl starch, and methyl starch; starch derivatives such as hydroxypropyltrimonium chloride starch and aluminum corn starch octenyl succinate; alginate derivatives such as sodium alginate and propylene glycol alginate; polyvinylpyridone (PVP), polyvinyl alcohol (PVA), vinylpyridone-vinyl alcohol copolymer, and polyvinyl methyl ether; polyethylene glycol, polypropylene glycol, and polyoxyethylene-polyoxypropylene copolymer; amphoteric methacrylate ester copolymers such as (methacryloyloxyethyl carboxybetaine / alkyl methacrylate) copolymer and (acrylates / stearyl acrylate / ethylamine oxide methacrylate) copolymer; (dimethicone / vinyl dimethicone) crosspolymer, (alkyl acrylate / diacetone acrylamide) copolymer, and (alkyl acrylate / diacetone acrylamide) copolymer AMP;Polyvinyl acetate partially saponified, maleic acid copolymer; vinylpyrrolidone dialkylaminoalkyl methacrylate copolymer; acrylic resin alkanolamine; polyester, water-dispersible polyester; polyacrylamide; polyacrylic acid ester copolymers such as ethyl polyacrylate, carboxyvinyl polymer, salts such as polyacrylic acid and its sodium salt, acrylic acid / methacrylic acid ester copolymer; acrylic acid / alkyl methacrylate copolymer; cationized cellulose such as polyquaternium-10, diallyldimethylammonium chloride / acrylamide copolymer such as polyquaternium-7, acrylic acid / diallyldimethylammonium chloride copolymer such as polyquaternium-22, acrylic acid / diallyldimethylammonium chloride / acrylamide copolymer such as polyquaternium-39, acrylic acid / cationized methacrylic acid ester copolymer, acrylic acid / cationized methacrylamide copolymer, polyquaternium-47, etc. Copolymers of lylic acid, methyl acrylate, methacrylamidopropyltrimethylammonium chloride, choline methacrylate ester polymer; cationized oligosaccharides, cationized dextran, guar hydroxypropyltrimonium chloride, and other cationized polysaccharides; polyethyleneimine; cationic polymers; polymers of 2-methacryloyloxyethyl phosphorylcholine such as polyquaternium-51 and butyl methacrylate copolymers, etc.; polymer emulsions such as acrylic resin emulsions, ethyl polyacrylate emulsions, polyacrylic alkyl ester emulsions, polyvinyl acetate resin emulsions, natural rubber latex, and synthetic latex; nitrocellulose; polyurethanes and various copolymers; various silicones; various silicone-based copolymers such as acrylic-silicone graft copolymers; various fluorine-based polymers; 12-hydroxystearic acid and its salts; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate;Preferred materials include anhydrous silicic acid, fuzzy silica (ultrafine particle anhydrous silicic acid), aluminum magnesium silicate, sodium magnesium silicate, metal soaps, dialkyl metal phosphates, bentonite, hectorite, organically modified clay minerals, sucrose fatty acid esters, and fructooligosaccharide fatty acid esters.

[0026] Preferred antioxidants include tocopherol (vitamin E), tocopherol derivatives such as tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and / or its derivatives; erythorbic acid and its derivatives; sulfites such as sodium sulfite; bisulfites such as sodium bisulfite; thiosulfates such as sodium thiosulfate; metabisulfites; thiotaurine, hypotaurine; thioglycerol, thiourea, thioglycolic acid, and cysteine ​​hydrochloride. Preferred reducing agents include thioglycolic acid, cysteine, and cysteamine. Preferred oxidizing agents include hydrogen peroxide, ammonium persulfate, sodium bromate, and percarbonate. Antioxidants include ascorbic acid, ascorbic acid phosphate salts such as sodium ascorbic acid phosphate and magnesium ascorbic acid phosphate; ascorbic acid fatty acid esters such as monostearate, monopalmitate, dipalmitate, and tetraisopalmitate; ascorbic acid ethers such as 3-O-ethyl ascorbic acid, 2-O-ethyl ascorbic acid, cetyl ascorbic acid, glyceryl ascorbic acid, and hexylglyceryl ascorbic acid; ascorbic acid glucosides such as ascorbic acid-2-glucoside and their fatty acid esters; and ascorbic acid Preferred materials include ascorbic acid derivatives such as sulfuric acid esters and tocopheryl ascorbyl phosphate; vitamin A compounds such as retinol, retinyl acetate, retinyl palmitate, and hydrogenated retinol; vitamin E compounds such as tocopherol, tocopherol acetate, and tocotrienol; carotenoids such as carotene, lycopene, astaxanthin, and lutein; polyphenols such as phlorotannin, curcumin, anthocyanin, proanthocyanidin, catechin, ellagic acid, quercetin, and apple polyphenols; and coenzyme Q10, lipoic acid, lactoferrin, sesamin, hesperidin, protoanthocyanidin, lignan, chlorogenic acid, rutin, fullerene, and platinum nanocolloids.

[0027] Whitening agents include hydroquinone glycosides and their esters such as arbutin and α-arbutin; ascorbic acid phosphate salts such as ascorbic acid, sodium ascorbic acid phosphate salt and magnesium ascorbic acid phosphate salt; ascorbic acid fatty acid esters such as ascorbic acid monostearate, ascorbic acid monopalmitate, ascorbic acid dipalmitate, and ascorbic acid tetraisopalmitate; and ascorbic acid esters such as 3-O-ethyl ascorbic acid, 2-O-ethyl ascorbic acid, cetyl ascorbic acid, glyceryl ascorbic acid, and hexylglyceryl ascorbic acid. Preferred materials include: ascorbic acid glucosides such as ascorbic acid-2-glucoside and their fatty acid esters; ascorbic acid derivatives such as ascorbic acid sulfate and tocopheryl ascorbyl phosphate; tranexamic acid derivatives such as tranexamic acid, tranexamic acid cetyl, and tranexamic acid amide; licorice extract-related substances such as glabridin, glabrene, liquiritin, and isoliquiritin; kojic acid, ellagic acid, ferulic acid and their derivatives, placenta extract, glutathione, oryzanol, butylresorcinol, oil-soluble chamomile extract, oil-soluble licorice extract, willow extract, and saxifrage extract.

[0028] Vitamins and their derivatives include vitamin A compounds such as retinol, retinyl acetate, and retinyl palmitate; vitamin B compounds such as thiamine hydrochloride, thiamine sulfate, riboflavin, riboflavin acetate, pyridoxine hydrochloride, pyridoxine dioctanoate, pyridoxine dipalmitate, flavin adenine dinucleotide, cyanocobalamin, folic acid compounds, nicotinic acid compounds such as nicotinamide and benzyl nicotinate, and choline compounds; vitamin C compounds such as ascorbic acid and its sodium salts; vitamin D; vitamin E compounds such as α, β, γ, and δ-tocopherols; other vitamins such as pantothenic acid and biotin; and ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt. Preferred materials include ascorbic acid phosphate salts, ascorbic acid fatty acid esters such as tetraisopalmitic ascorbate, ascorbyl stearate, ascorbyl palmitate, and ascorbyl dipalmitate, alkyl ascorbic acid ethers such as ethyl ascorbate, ascorbic acid glucosides such as ascorbic acid-2-glucoside and their fatty acid esters, ascorbic acid derivatives such as tocopheryl ascorbyl phosphate; vitamin derivatives such as tocopherol nicotinate, tocopherol acetate, tocopherol linoleate, tocopherol ferulate, and tocopherol phosphate esters, tocotrienols, and various other vitamin derivatives.

[0029] Plant, animal, and microbial extracts include iris extract, angelica extract, Thujopsis dolabrata extract, asparagus extract, avocado extract, Hydrangea macrophylla extract, almond extract, marshmallow extract, arnica extract, aloe extract, apricot extract, apricot kernel extract, ginkgo extract, fig extract, fennel extract, turmeric extract, oolong tea extract, bearberry extract, rosehip extract, Echinacea leaf extract, Enmeisou extract, scutellaria extract, phellodendron bark extract, Coptis japonica extract, barley extract, ginseng extract, St. John's wort extract, and Lamium album. Grass extract, Ononis extract, Nasturtium extract, Orange extract, Dried seawater, Seaweed extract, Persimmon leaf extract, Arctium extract, Hydrolyzed elastin, Hydrolyzed wheat powder, Hydrolyzed silk, Pueraria lobata extract, Chamomile extract, Oil-soluble chamomile extract, Carrot extract, Artemisia capillaris extract, Oat extract, Chloranthus extract, Licorice extract, Oil-soluble licorice extract, Kiwi extract, Kelp extract, Wood ear mushroom extract, Cinchona extract, Cucumber extract, Paulownia leaf extract, Guanosine, Guava extract, Sophora flavescens extract, Gardenia extract, Sasa veitchii extract, Sophora flavescens extract, walnut extract, chestnut extract, grapefruit extract, clematis extract, black rice extract, brown sugar extract, black vinegar extract, chlorella extract, mulberry extract, gentian extract, Geranium thunbergii extract, black tea extract, yeast extract, Magnolia bark extract, coffee extract, burdock extract, rice extract, rice fermentation extract, rice bran fermentation extract, rice germ oil, comfrey extract, collagen, lingonberry extract, Asarum sieboldii extract, Bupleurum chinense extract, umbilical cord extract, saffron extract, sage extract, soapwort extract, bamboo extract, hawthorn extract, sunflower extract Kiss, Japanese pepper extract, shiitake mushroom extract, rehmannia extract, lithospermum extract, perilla extract, linden extract, meadowsweet extract, jatoba extract, peony extract, ginger extract, calamus root extract, birch extract, white fungus extract, horsetail extract, stevia extract, stevia ferment, iris extract, ivy extract, hawthorn extract, elderberry extract, yarrow extract, peppermint extract, sage extract, mallow extract, chuanxiong extract, swertia japonica extract, mulberry bark extract, rhubarb extract,Soybean extract, jujube extract, thyme extract, dandelion extract, lichen extract, tea extract, clove extract, cogongrass extract, citrus peel extract, tea tree oil, sweet tea extract, chili pepper extract, angelica extract, calendula extract, peach kernel extract, spruce extract, Houttuynia cordata extract, tomato extract, natto extract, carrot extract, garlic extract, wild rose extract, hibiscus extract, Ophiopogon extract, lotus extract, parsley extract, birch extract, honey, witch hazel extract, parietaria extract, Isodon japonicus extract, bisabolol, cypress extract, bifidobacteria extract, loquat extract, coltsfoot extract, butterbur extract, Poria cocos extract, butcher's broom extract, grape extract, grape seed extract Preferred extracts include those of kiss, propolis, loofah extract, safflower extract, peppermint extract, linden extract, peony extract, hop extract, cypress extract, pine extract, horse chestnut extract, skunk cabbage extract, soapberry extract, lemon balm extract, seaweed extract, peach extract, cornflower extract, eucalyptus extract, saxifrage extract, yuzu extract, lily extract, coix seed extract, mugwort extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, rooibos tea extract, reishi mushroom extract, lettuce extract, lemon extract, forsythia extract, astragalus extract, rose extract, rosemary extract, Roman chamomile extract, royal jelly extract, and Sanguisorba officinalis extract.

[0030] UV absorbers include benzoic acid-based UV absorbers such as para-aminobenzoic acid, para-aminobenzoic acid monoglycerol ester, N,N-dipropoxypara-aminobenzoate ethyl ester, N,N-diethoxypara-aminobenzoate ethyl ester, N,N-dimethylpara-aminobenzoate ethyl ester, N,N-dimethylpara-aminobenzoate butyl ester, and N,N-dimethylpara-aminobenzoate ethyl ester; anthranilic acid-based UV absorbers such as homomenthyl-N-acetylanthranilate; salicylic acid-based UV absorbers such as salicylic acid and its sodium salt, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, and p-isopropanolphenyl salicylate; and octyl cinnamate. Cinnamic acid-based UV absorbers such as ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, ethyl-2,4-diisopropyl cinnamate, methyl-2,4-diisopropyl cinnamate, propyl-p-methoxy cinnamate, isopropyl-p-methoxy cinnamate, isoamyl-p-methoxy cinnamate, 2-ethylhexyl-p-methoxy cinnamate (octyl paramethoxycinnamate), 2-ethoxyethyl-p-methoxy cinnamate (cinoxate), cyclohexyl-p-methoxy cinnamate, ethyl-α-cyano-β-phenyl cinnamate, 2-ethylhexyl-α-cyano-β-phenyl cinnamate (octocrine), glyceryl mono-2-ethylhexanoyl-diparamethoxy cinnamate, ferulic acid and its derivatives;Benzophenone-based UV absorbers such as 2,4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone (oxybenzone-3), 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4'-phenylbenzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone; 3-(4'-methylbenzylidene)-d,l-camphor, 3-benzylidene-d,l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5-methylphenylbenzotriazole; 2-(2'-hydro Xy-5'-t-octylphenyl)benzotriazole; 2-(2'-hydroxy-5'-methylphenylbenzotriazole; dibenzarazine; dianisioylmethane; 5-(3,3-dimethyl-2-norbornylidene)-3-pentan-2-one; dibenzoylmethane derivatives such as 4-t-butyl methoxydibenzoylmethane; octyltriazone; urocanic acid derivatives such as urocanic acid and ethyl urocanic acid; 2-(2'-hydroxy-5'-methylphenyl)benzotriazole; Preferred materials include benzotriazole (nyl), 1-(3,4-dimethoxyphenyl)-4,4-dimethyl-1,3-pentanedione, 2-ethylhexyl dimethoxybenzylidene dioxoimidazolidinepropionate, and other hydantoin derivatives, phenylbenzimidazol sulfonic acid, terephthalylidene dicamphor sulfonic acid, drometrizole trisiloxane, methyl anthranilate, rutin and its derivatives, and oryzanol and its derivatives.

[0031] As antibacterial and preservative agents, parabens (hydroxybenzoic acid esters) such as methylparaben, ethylparaben, propylparaben, and butylparaben; phenoxyethanol; 1,2-alkanediols such as 1,2-pentanediol, 1,2-hexanediol, and 1,2-octanediol; alkylglyceryl ethers such as 2-ethylhexylglyceryl ether (ethylhexylglycerin); salicylic acid; lanolin fatty acids and their salts; sodium benzoate; isothiazolinone derivatives such as methylchloroisothiazolinone and methylisothiazolinone; imidazolinium urea; dehydroacetic acid and its salts; phenols; halogenated bisphenols such as triclosan, acid amides, quaternary ammonium salts; trichlorocarbanide, zinc pyrithione, benzalconium chloride Preferred substances include benzethonium chloride, sorbic acid, chlorhexidine, chlorhexidine gluconate, halocarban, hexachlorophene, hinokitiol; phenols, isopropylphenol, cresol, thymol, parachlorophenol, phenylphenol, sodium phenylphenol and other phenols; phenylethyl alcohol, photosensitizers, antimicrobial zeolites, and silver ions. However, when used as an antimicrobial agent or preservative for preservation purposes, from the viewpoint of safety for cosmetics or topical skin preparations, it is more preferable to use phenoxyethanol; 1,2-alkanediols such as 1,2-pentanediol, 1,2-hexanediol, and 1,2-octanediol; and alkylglyceryl ethers such as 2-ethylhexylglyceryl ether.

[0032] Preferred chelating agents include edetates (ethylenediaminetetraacetates) such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na; hydroxyethylethylenediaminetriacetates such as HEDTA3Na; pentetates (diethylenetriaminepentaacetate); phytic acid; phosphonic acids such as etidronic acid and their sodium salts; sodium oxalate; polypolyamino acids such as polyaspartic acid and polyglutamic acid; sodium polyphosphate, sodium metaphosphate, phosphoric acid; sodium citrate, citric acid, alanine, dihydroxyethylglycine, gluconic acid, ascorbic acid, succinic acid, and tartaric acid.

[0033] Preferred pH adjusters, acids, and alkalis include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, monoethanolamine, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol, arginine, sodium hydroxide, potassium hydroxide, aqueous ammonia, guanidine carbonate, and ammonium carbonate.

[0034] Solvents and propellants include lower alcohols such as ethanol, 2-propanol (isopropyl alcohol), butanol, and isobutyl alcohol; glycols such as propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol, and isopentyl diol; diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, and di Preferred propellants include glycol ethers such as propylene glycol monoethyl ether; glycol ether esters such as ethylene glycol monoethyl ether acetate, diethylene glycol monoethyl ether acetate, and propylene glycol monoethyl ether acetate; glycol esters such as diethoxyethyl succinate and ethylene glycol disuccinate; benzyl alcohol, benzyloxyethanol, propylene carbonate, dialkyl carbonate, acetone, ethyl acetate, N-methylpyrrolidone; toluene; fluorocarbons, next-generation chlorofluorocarbons; LPG, dimethyl ether, and carbon dioxide.

[0035] Examples of antipruritic agents include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, and substance-P inhibitors. Examples of exfoliating and dissolving agents include salicylic acid, sulfur, resorcinol, selenium sulfide, pyridoxine, and glycolic acid. Examples of antiperspirants include aluminum chlorohydrate, aluminum chloride, zinc oxide, and zinc paraphenolsulfonate. Examples of cooling agents include menthol and methyl salicylate. Examples of astringent agents include citric acid, tartaric acid, lactic acid, potassium aluminum sulfate, tannic acid, and caffeine. Examples of enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, and protease. Preferred nucleic acids include ribonucleic acid and its salts, deoxyribonucleic acid and its salts, and adenosine triphosphate disodium.

[0036] Preferred anti-inflammatory agents include glycyrrhizic acid and its derivatives, glycyrrhetinic acid derivatives, salicylic acid and its derivatives, azelaic acid and its derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, prednisone, diphedramine hydrochloride, chlorpheniramine maleate; and plant extracts such as peach leaf extract and mugwort leaf extract. Preferred hair growth agents, blood circulation promoters, and stimulants include plant extracts and tinctures such as Swertia japonica extract, Capsicum tincture, Ginger tincture, Ginger extract, and Cantharis tincture; capsaicin, nonylic acid valenylamide, gingerol, ichthammol, tannic acid, borneol, cyclandelate, cinnarizine, trazoline, acetylcholine, verapamil, cepharanthine, γ-oryzanol, cepharanthine, vitamin E and derivatives such as tocopherol nicotinate and tocopherol acetate; γ-oryzanol, nicotinic acid and derivatives such as nicotinamide, benzyl nicotinate, inositol hexanicotinate, and nicotinic alcohol; allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, flavanonol derivatives, stigmasterol or stigmamanol and its glycosides; and minoxidil. Preferred hormones include estradiol, estrone, ethinylestradiol, cortisone, hydrocortisone, and prednisone.

[0037] Anti-wrinkle and anti-aging agents include: ascorbic acid, ascorbic acid phosphate salts such as sodium ascorbic acid phosphate and magnesium ascorbic acid phosphate; ascorbic acid fatty acid esters such as monostearate, monopalmitate, dipalmitate, and tetraisopalmitate; ascorbic acid ethers such as 3-O-ethyl ascorbic acid, 2-O-ethyl ascorbic acid, cetyl ascorbic acid, glyceryl ascorbic acid, and hexylglyceryl ascorbic acid; ascorbic acid glucosides and their fatty acid esters such as ascorbic acid-2-glucoside; and ascorbic acid derivatives such as ascorbic acid sulfate and tocopheryl ascorbyl phosphate. Preferred materials include: Vitamin A compounds such as retinol, retinyl acetate, retinyl palmitate, and hydrogenated retinol; nicotinamide, glutathione, cysteine, crocetin, sericin, geraniol, glycerin glucoside, lactoferrin, proanthocyanidin, pantothenic acid, panthenol, soy saponin, revelastol, isoflavone, coenzyme Q10, chondroitin sulfate, acetylglucosamine, glycerophosphatidylcholine, hydrolyzed hyaluronic acid, collagen peptide, conchiolin hydrolysate, adenosine 5'-monophosphate, phosphatidylinositol, sodium trifluoride isopropyl oxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetate, tranexamic acid and its derivatives.

[0038] Preferred irritation-reducing agents include mannosylerythritol lipid, diethylene glycol dimer dilinoleate oligomer ester, diisostearyl malate, N-acyl-L-glutamic acid, trehalose monofatty acid ester, fatty acid amidoamine oxide, alkyldimethylamine oxide, phenylethyl glucoside, lauryl glucoside, ferulic acid glucoside, salicin, cedrol, polyethylene glycol, and polypropylene glycol. Preferred cooling agents include menthol, camphor, menthyl lactate, monomentyl succinate, menthyl acetate, borneol, cineole, thymol, peppermint oil, and derivatives thereof. Preferred warming agents include vanillin and its derivatives, vanillyl nonanoate, gingerol, capsicum tincture, capsicum extract, benzyl nicotinate, methyl nicotinate, phenyl nicotinate, tocopherol nicotinate and other nicotinic acid derivatives, capsaicin, watercress extract, sansho pepper extract, ginger extract, and canthari extract.

[0039] Powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, red mica, biotite, vermiculite, magnesium carbonate, calcium carbonate, aluminum silicate, barium silicate, calcium silicate, magnesium silicate, strontium silicate, tungstate metal salts, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluorapatite, hydroxyapatite, ceramic powder, bentonite, smectite, clay, mud, metal soaps (e.g., zinc myristate, calcium palmitate, aluminum stearate), calcium carbonate, red iron oxide, yellow iron oxide, black iron oxide, ultramarine, Prussian blue, carbon black, titanium dioxide, fine and ultrafine titanium dioxide, zinc oxide, fine and ultrafine zinc oxide, alumina, silica, fuzzy silica (ultrafine anhydrous silicic acid), and titanium mica. Preferred materials include inorganic powders of various sizes and shapes such as fish scale foil, boron nitride, photochromic pigments, synthetic fluorphlogopite, fine particle composite powders, gold, aluminum, and inorganic powders that have been hydrophobized or hydrophilized by treating them with various surface treatment agents such as hydrogen silicone, cyclic hydrogen silicone, or other silanes or titanium coupling agents; organic powders of various sizes and shapes such as starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, styrene-acrylic acid copolymer resin powder, polyester powder, benzoguanamine resin powder, polyethylene terephthalate-polymethyl methacrylate laminated powder, polyethylene terephthalate-aluminum-epoxy laminated powder, urethane powder, silicone powder, Teflon® powder, and other organic powders and surface-treated powders, as well as organic-inorganic composite powders.Preferred inorganic salts include sodium chloride-containing salts such as table salt, regular salt, rock salt, sea salt, and natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, and ammonium chloride; sodium sulfate, aluminum sulfate, aluminum potassium sulfate (alum), aluminum ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, iron sulfate, and copper sulfate; and sodium phosphates such as 1Na, 2Na, and 3Na phosphates, potassium phosphates, calcium phosphates, and magnesium phosphates.

[0040] As pigments, colorants, dyes, and dyes, these include Brown No. 201, Black No. 401, Purple No. 201, Purple No. 401, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 202, Blue No. 203, Blue No. 204, Blue No. 205, Blue No. 403, Blue No. 404, Green No. 3, Green No. 201, Green No. 202, Green No. 204, Green No. 205, Green No. 3, Green No. 401, Green No. 402 Red No. 102, Red No. 104-1, Red No. 105-1, Red No. 106, Red No. 2, Red No. 3, Red No. 201, Red No. 202, Red No. 203, Red No. 204, Red No. 205, Red No. 206, Red No. 207, Red No. 208, Red No. 213, Red No. 214, Red No. 215, Red No. 218, Red No. 219, Red No. 220, Red No. 221, Red No. 223 , Red No. 225, Red No. 226, Red No. 227, Red No. 228, Red No. 230-1, Red No. 230-2, Red No. 231, Red No. 232, Red No. 3, Red No. 401, Red No. 40 No. 4, Red No. 405, Red No. 501, Red No. 502, Red No. 503, Red No. 504, Red No. 505, Red No. 506, Orange No. 201, Orange No. 203, Orange No. 204, Orange 20 Statutory dyes such as No. 5, Orange No. 206, Orange No. 207, Orange No. 401, Orange No. 402, Orange No. 403, Yellow No. 201, Yellow No. 202-1, Yellow No. 202-2, Yellow No. 203, Yellow No. 204, Yellow No. 205, Yellow No. 4, Yellow No. 401, Yellow No. 402, Yellow No. 403-1, Yellow No. 404, Yellow No. 405, Yellow No. 406, Yellow No. 407, Yellow No. 5, etc.; Acid Other acid dyes such as Red 14; basic dyes such as Arianor Sienna Brown, Arianor Madder Red, Arianor Steel Blue, and Arianor Straw Yellow; nitro dyes such as HC Yellow 2, HC Yellow 5, HC Red 3, 4-hydroxypropylamino-3-nitrophenol, N,N'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine, HC Blue 2, and Basic Blue 26; disperse dyes; inorganic white pigments such as titanium dioxide and zinc oxide; inorganic red pigments such as iron oxide (red iron oxide) and iron titanate; inorganic brown pigments such as γ-iron oxide; inorganic yellow pigments such as yellow iron oxide and ochre; inorganic black pigments such as black iron oxide and lower titanium oxide;Inorganic purple pigments such as mango violet and cobalt violet; inorganic green pigments such as chromium oxide, chromium hydroxide, and cobalt titanate; inorganic blue pigments such as ultramarine and Prussian blue; pearl pigments such as titanium dioxide-coated mica, titanium dioxide-coated bismuth oxychloride, titanium dioxide-coated talc, colored titanium dioxide-coated mica, bismuth oxychloride, and fish scale foil; metal powder pigments such as aluminum powder, copper powder, and gold; anthraquinones such as astaxanthin and alizarin, anthocyanidins, β-carotene, catenal, capsanthin, chalcone, calsamine, quercetin Natural pigments and dyes such as tin, crocin, chlorophyll, curcumin, naphthoquinones such as cochineal and shikonin, bixin, flavones, betacyanidin, henna, hemoglobin, lycopene, riboflavin, and rutin; oxidative dye intermediates and couplers such as p-phenylenediamine, toluene-2,5-diamine, o-,m-, or p-aminophenol, m-phenylenediamine, 5-amino-2-methylphenol, resorcinol, 1-naphthol, 2,6-diaminopyridine, and their salts; auto-oxidative dyes such as indoline; and dihydroxyacetone are preferred.

[0041] The fragrance ingredients include acetylcedrene, amyl cinnamaldehyde, allyl amyl glycolate, β-ionone, iso-esuper, isobutylquinoline, iris oil, ylone, indole, ylang-ylang oil, undecanal, undecenal, γ-undecalactone, estragol, eugenol, oakmoss, opoponax resinoid, orange oil, eugenol, aurantiol, galacsolid, carvacrol, L-carbone, camphor, canone, carrot seed oil, clove oil, methyl cinnamate, geraniol, geranyl nitrile, isobornyl acetate, geranyl acetate, dimethylbenzylcarbinyl acetate, styraryl acetate, cedyl acetate, terepinel acetate, and pt-butylcyclohexyl acetate. Lu, vetiveryl acetate, benzyl acetate, linalyl acetate, isopentyl salicylate, benzyl salicylate, sandalwood oil, santalol, cyclamenaldehyde, cyclopentadecanol, methyl dihydrojasmonate, dihydromyrcenol, jasmine absolute, jasmine lactone, cis-jasmone, citral, citronenol, citronellal, cinnamon bark oil, 1,8-cineole, cinnamaldehyde, styrax resinoid, cedarwood oil, cedrene, cedrol, celery seed oil, thyme oil, damascone, damascenone, thymol, tuberose absolute, decanal, decalactone, terpineol, γ-terpinene, tripral, nerol, nonanal, 2,6-Nonadienol, Nonalactone, Patchouli Alcohol, Vanilla Absolute, Vanillin, Basil Oil, Patchouli Oil, Hydroxycitronellal, α-Pinene, Piperitone, Phenethyl Alcohol, Phenylacetaldehyde, Petitgrain Oil, Hexyl Cinnamaldehyde, cis-3-Hexenol, Peruvian Balsam, Vetiver Oil, Vetiverol, Peppermint Oil, Pepper Oil, Heliotropin, Bergamot Oil, Benzyl Benzoate Preferred examples include synthetic and natural fragrances such as benzoate, borneol, myrrhizinoid, musk ketone, methylnonylacetaldehyde, γ-methylionone, menthol, L-menthol, L-menthone, eucalyptus oil, β-ionone, lime oil, lavender oil, D-limonene, linalool, liral, lilial, lemon oil, rose absolute, rose oxide, rose oil, rosemary oil, various essential oils, and various blended fragrances.

[0042] In addition to tap water and purified water, preferred types of water include hard water, soft water, natural water, deep-sea water, electrolyzed alkaline ionized water, electrolyzed acidic ionized water, ionized water, and clustered water.

[0043] In addition to these, it is possible to include known cosmetic ingredients, pharmaceutical ingredients, food ingredients, etc., in known combinations, formulation ratios, and amounts, such as ingredients listed in the Cosmetic Raw Material Standards, Cosmetic Ingredient Formulation Standards, Japan Cosmetic Industry Association Ingredient Labeling Name List, INCI Dictionary (The International Cosmetic Ingredient Dictionary and Handbook), Quasi-drug Raw Material Standards, Japanese Pharmacopoeia, Pharmaceutical Additives Standards, Food Additives Compendium, etc., as well as ingredients listed in Japanese and foreign patent gazettes and patent publications (including published and republished gazettes) belonging to the International Patent Classification IPC A61K7 and A61K8 classifications.

[0044] Examples of cosmetic compositions of the present invention include hair cosmetics, skin cosmetics, makeup cosmetics, fragrance cosmetics, and body cosmetics. Cosmetics of the present invention can be manufactured according to conventional methods.

[0045] To further describe the types of cosmetics of the present invention, preferred hair cosmetics include shampoos such as oil shampoos, cream shampoos, conditioning shampoos, anti-dandruff shampoos, hair color shampoos, and rinse-integrated shampoos; hair care products such as rinses, conditioners, treatments, hair packs, leave-on treatments, hair mists, and hair oils; hair styling products such as hair foams, hair mousses, hair sprays, hair waxes, hair gels, hair creams, water greases, setting lotions, pomades, and hair sticks; hair dyes such as color lotions, hair color treatments, hair manicures, and oxidative hair dyes; and hair tonics, hair liquids, hair blowers, split end coats, permanent wave agents, straight perm agents, hair bleaches, hair color pre-treatments, hair color after-treatments, perm pre-treatments, perm after-treatments, and hair growth agents.

[0046] Skin cosmetics include toners such as softening toners, astringent toners, cleansing toners, multi-layer toners, and liposome toners; lotions such as emollient lotions, moisturizing lotions, milky lotions, nourishing lotions, nourishing milks, skin moisturizers, moisturizing emulsions, massage lotions, exfoliating smoothers, elbow lotions, hand lotions, and body lotions; emollient creams, nourishing creams, nourishing creams, vanishing creams, moisturizing creams, night creams, massage creams, cleansing creams, makeup creams, base creams, pre-makeup creams, sunscreen creams, suntan creams, hair removal creams, deodorant creams, shaving creams, and exfoliating creams. Preferred products include skincare cosmetics such as creams including softening creams, moisturizing gels, whitening gels, all-in-one gels, moisturizing essences, whitening essences, moisturizing serums, whitening serums, and other beauty serums; sunscreen cosmetics such as sun protectors, sun protectors, UV care milks, and sunscreens; packs and masks such as peel-off packs, powder packs, washing packs, oil packs, and cleansing masks; cleansing cosmetics such as cleansing foams, cleansing creams, cleansing milks, cleansing lotions, cleansing gels, and cleansing oils; and facial cleansers such as paste facial cleansing foams, gel facial cleansing foams, foaming facial cleansing foams, facial cleansing powders, cosmetic soaps, clear soaps, medicated soaps, liquid soaps, and shaving soaps.

[0047] Preferred makeup products include lipstick, lip gloss, foundation, blush, face powder, concealer, eyeliner, mascara, eyeshadow, eyebrow pencil, eyebrow products, nail polish, nail polish remover, and nail treatment.

[0048] Preferred fragranced cosmetics include perfumes, fragrances, parfums, eau de parfums, eau de toilettes, eau de colognes, solid perfumes, fragrance powders, fragranced soaps, body lotions, and bath oils.

[0049] Preferred body cosmetics include body washes such as body shampoos, deodorant lotions, deodorant powders, deodorant sprays, deodorant sticks, deodorizing cosmetics, bleaching agents, hair removal agents, bath additives, and insect repellents such as insect repellent sprays.

[0050] The present invention can be used as a topical skin preparation in the form of an ointment, lotion, cream or gel, patch, liniment, or liquid application. It can also be used as an oral cosmetic such as toothpaste or mouthwash.

[0051] Preferred dosage forms for the cosmetic or topical skin preparation of the present invention include emulsified cosmetics such as oil-in-water (O / W) type, water-in-oil (W / O) type, W / O / W type, and O / W / O type, as well as oily cosmetics, solid cosmetics, liquid cosmetics, paste cosmetics, stick cosmetics, volatile oil-type cosmetics, powder cosmetics, jelly-type cosmetics, gel-type cosmetics, paste-type cosmetics, emulsified polymer-type cosmetics, sheet-type cosmetics, mist-type cosmetics, and spray-type cosmetics.

[0052] The present invention will be further described in detail by the following examples, but the present invention is not limited thereto.

[0053] Aqueous dispersion compositions of the present invention and aqueous dispersion compositions outside the scope of the present invention were prepared with the compositions shown in Tables 1-3. The transparency and dispersion stability of the obtained aqueous dispersion compositions were evaluated using the following method, and the results are shown in the lower section of Tables 1-3. <Method for preparing an aqueous dispersion composition> Components (A) and (B) were pre-mixed by stirring at 80°C to prepare a polyhydric alcohol solution. The resulting polyhydric alcohol solution was added while stirring to an aqueous solution of phenoxyethanol and component (C) that had been heated and dissolved at 80°C, and the mixture was stirred in a homomixer (75°C, 5000 rpm, 15 minutes) and then cooled. <Method for evaluating transparency> The obtained aqueous dispersion composition was placed in a 3.5 cm diameter glass bottle, and its appearance was visually observed from the side. Transparency was evaluated according to the following evaluation criteria. ○...The liquid is clearly visible through it. △...The liquid is slightly transparent behind it. ×...The liquid behind it is not visible. <Method for evaluating dispersion stability> The obtained aqueous dispersion compositions were visually observed after being stored at 50°C for one month, and their dispersion stability was evaluated according to the following criteria. ○...No change in appearance from the initial version. △···The appearance has changed slightly since the initial version. ×...The appearance has changed significantly since the initial stages.

[0054] [Table 1]

[0055] [Table 2]

[0056] [Table 3]

[0057] The results shown in Tables 1-3 indicate that the aqueous dispersion composition of the present invention exhibited high transparency and excellent dispersion stability.

[0058] The following cosmetic products were developed. The skin cosmetic product has excellent moisturizing and penetrating properties and prevents fine lines and rough skin. The hair cosmetic product has excellent moisturizing, penetrating, and damage care effects. The makeup cosmetic product has excellent moisturizing properties, adherence to the skin, and smoothness.

[0059] Example 10: Aqueous dispersion composition Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 5.0 Mannosylerythritol Lipid (MEL-B) 5.0 Ceramide 6 2.0 1,2-Hexanediol 10.0 BG 15.0 Part B Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and while stirring with a homomixer (7000 rpm), part A was added to part B and cooled to room temperature.

[0060] Example 11: Aqueous dispersion composition Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 5.0 Mannosylerythritol Lipid (MEL-B) 5.0 Ceramide 6 2.0 1,2-Hexanediol 10.0 BG 15.0 Part B Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and while stirring with a homomixer (7000 rpm), part A was added to part B and cooled to room temperature.

[0061] Example 12: Aqueous dispersion composition Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 3.5 Mannosylerythritol lipid (MEL-B) 2.5 Ceramide 3 1.5 1,2-Hexanediol 10.0 BG 5.0 Part B Phenoxyethanol 0.4 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and while stirring with a homomixer (7000 rpm), part A was added to part B and cooled to room temperature.

[0062] Example 13: Aqueous dispersion composition Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 3.5 Mannosylerythritol lipid (MEL-B) 2.5 Ceramide 3 1.5 1,2-Hexanediol 10.0 BG 5.0 Part B Phenoxyethanol 0.4 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and while stirring with a homomixer (7000 rpm), part A was added to part B and cooled to room temperature.

[0063] Example 14: Aqueous dispersion composition Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 4.5 Mannosylerythritol lipid (MEL-B) 3.5 Ceramide 1 0.2 Ceramide 2 0.2 Ceramide 3 0.2 Ceramide 4 0.2 Ceramide 5 0.2 Ceramide 6 0.2 1,2-Hexanediol 10.0 BG 10.0 Part B Phenoxyethanol 0.4 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and while stirring with a homomixer (7000 rpm), part A was added to part B and cooled to room temperature.

[0064] Example 15: Aqueous dispersion composition Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 4.5 Mannosylerythritol lipid (MEL-B) 3.5 Ceramide 1 0.2 Ceramide 2 0.2 Ceramide 3 0.2 Ceramide 4 0.2 Ceramide 5 0.2 Ceramide 6 0.2 1,2-Hexanediol 10.0 BG 10.0 Part B Phenoxyethanol 0.4 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and while stirring with a homomixer (7000 rpm), part A was added to part B and cooled to room temperature.

[0065] Example 16: Aqueous Dispersible Composition Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 5.0 Mannosylerythritol lipid (MEL-B) 2.5 Ceramide 2 2.0 1,2-Hexanediol 10.0 BG 10.0 Part B Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and while stirring with a homomixer (7000 rpm), part A was added to part B and cooled to room temperature.

[0066] Example 17: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Aqueous dispersion composition of Example 10 20.0 Neosolue-Aqulio (Nippon Seika) 1.0 Tremoist-TP (Nippon Fine Chemical) 0.1 Nicotinamide 5.0 Tranexamic acid (Nippon Seika) 1.0 EDTA-2Na 0.05 Phenoxyethanol 0.4 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) All ingredients were mixed together to form a homogeneous liquid.

[0067] Example 18: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Mannosylerythritol lipid (MEL-B) 0.3 Ceramide 6 0.2 BG 5.0 1,2-Pentanediol 3.0 Part B Purified water, in an amount that totals 100. C part Neosolue-Aqulio (Nippon Seika) 1.0 Nicotinamide 5.0 Glucosylceramide 0.5 Tremoist-TP (Nippon Fine Chemical) 0.1 EDTA-2Na 0.05 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Parts A and B were heated to approximately 80°C. Part A was added to part B while stirring with a homomixer (7000 rpm), and after cooling, part C was added to create a homogeneous liquid.

[0068] Example 19: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.3 Mannosylerythritol lipid (MEL-B) 0.4 Ceramide 3 0.1 1,2-Pentanediol 5.0 Part B Phenoxyethanol 0.4 Citric acid 0.2 Sodium citrate (appropriate amount) Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to approximately 80°C. Part A was added to part B while stirring with a homomixer (7000 rpm), and after cooling, part C was added to create a homogeneous solution. Sodium citrate was added to achieve a pH of 6.5-7.0.

[0069] Example 20: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 0.5 Mannosylerythritol lipid (MEL-B) 1.5 Ceramide 1 0.15 BG 10.0 Part B Purified water, in an amount that totals 100. C part Carbomer 0.1 Arginine 0.1 Hydroxyethylcellulose 0.2 Phenoxyethanol 0.4 Purified water 20.0 -------------------------------------- (Preparation method) Parts A and B were heated to approximately 80°C. Part C was stirred to make a viscous liquid. Part A was added to part B while stirring with a homomixer (7000 rpm) to make a homogeneous liquid. After cooling, part C was added to make a homogeneous liquid.

[0070] Example 21: Moisturizing lotion Component Amount (% by weight) ------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 0.5 Mannosylerythritol lipid (MEL-B) 0.4 Ceramide 2 0.1 Diglycerin 1.0 Glycerin 8.0 BG 3.0 Plandool-LG2 (Nippon Seika) 0.001 Plandool-ISS (Nippon Fine Chemical) 0.005 Part B Purified water 40.0 C part Maltitol solution 1.0 Betaine 0.5 α-Glucan oligosaccharide 0.1 Pullulan 0.5 Tuberose polysaccharide 0.01 Hydroxypropyl methylcellulose stearoxy ether 0.05 (Acrylates / C10-30 Alkyl Acrylate) Crosspolymer 0.05 Arginine 0.05 Phenoxyethanol 0.2 Methylparaben 0.15 Purified water, in an amount that totals 100. ------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and part A was added to part B while stirring with a homomixer (7000 rpm). Further dispersion was achieved using a high-pressure emulsifier (Mizuho Industries Microfluidizer). After cooling, part C, which had been mixed beforehand, was added to create a homogeneous liquid.

[0071] Example 22: Moisturizing lotion Component Amount (% by weight) ------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Mannosylerythritol Lipid (MEL-B) 1.0 Ceramide 5 0.3 Diglycerin 1.0 BG 3.0 1,2-Pentanediol 3.0 Plandool-LG2 (Nippon Seika) 0.05 Part B Purified water 30.0 C part Betaine 0.5 Nicotinamide 5.0 Tranexamic acid (Nippon Seika) 1.0 Phenoxyethanol 0.2 Purified water, in an amount that totals 100. ------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and part A was added to part B while stirring with a homomixer (7000 rpm). After cooling, part C, which had been mixed beforehand, was added to create a homogeneous liquid.

[0072] Example 23: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 0.5 Mannosylerythritol Lipid (MEL-B) 1.0 Ceramide 6 0.2 Ceramide 3 0.2 Ceramide 2 0.1 BG 2.0 1,2-Hexanediol 3.0 Part B Neosolue-Aqulio (Nippon Seika) 1.0 Tranexamic acid (Nippon Seika) 2.0 Arbutin (Nippon Seika) 2.0 Phenoxyethanol 0.4 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were uniformly mixed at approximately 70°C. Part A was added to part B while stirring with a homomixer (7000 rpm), and then cooled.

[0073] Example 24: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 0.8 Mannosylerythritol lipid (MEL-B) 0.5 Ceramide 6 0.1 Ceramide 3 0.1 Ceramide 2 0.1 BG 2.0 1,2-Pentanediol 3.0 Part B Purified water, in an amount that totals 100. C part Sodium cyclic lysophosphatidic acid 0.001 Neosolue-AquaS (Nippon Fine Chemical) 1.0 PEG / PPG / Polybutylene Glycol-8 / 5 / 3 Glycerin 0.5 Polyquaternium-51 0.5 Phenoxyethanol 0.2 Methylparaben 0.15 Purified water 20.0 -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and part A was added to part B while stirring with a propeller. After cooling, part C, which had been mixed beforehand, was added to create a homogeneous liquid.

[0074] Example 25: Whitening lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 0.5 Mannosylerythritol lipid (MEL-B) 0.6 Ceramide 5 0.3 Glycerin 8.0 DPG 2.0 1,3-Propanediol 7.0 Part B Purified water 50.0 C part 3-O-ethyl ascorbic acid (Nippon Seika) 1.0 Arbutin (Nippon Seika) 1.0 Ethanol 3.0 Methylgluceth-10 2.0 Dipotassium glycyrrhizate 0.05 Tremoist-TP (Nippon Fine Chemical) 0.01 Xanthan gum 0.05 Phenoxyethanol 0.2 Methylparaben 0.15 Citric acid 0.1 Sodium citrate 0.2 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and part A was added to part B while stirring with a homomixer (7000 rpm). After cooling, part C, which had been mixed beforehand, was added to create a homogeneous liquid.

[0075] Example 26: Whitening lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 3.0 Mannosylerythritol Lipid (MEL-B) 1.0 Ceramide 2 0.3 Glabridin 0.05 BG 10.0 Part B Purified water 40.0 C part Tranexamic acid (Nippon Seika) 2.0 Nicotinamide 5.0 Phytic acid 0.3 Tripropylene glycol 2.0 Sodium hyaluronate 0.01 DPG 2.0 Carbomer 0.01 Phenoxyethanol 0.4 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and part A was added to part B while stirring with a homomixer (7000 rpm). After cooling, part C, which had been mixed beforehand, was added to create a homogeneous liquid.

[0076] Example 27: Gel lotion Component Amount (% by weight) ------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 0.5 Mannosylerythritol Lipid (MEL-B) 1.0 Ceramide 6 0.3 1,2-Pentanediol 3.0 BG 3.0 Part B Polyglyceryl-6 laurate 1.0 Sorbitol solution (70%) 5.0 Purified water 30.0 C part Glycerin 10.0 Glucose 1.0 Pullulan 0.2 Ethylhexylglycerin 0.2 Polymethacryloyl lysine 0.05 Crystalline cellulose powder 0.1 Locust bean gum 0.03 Hydroxyethylcellulose 0.05 Xanthan gum 0.05 Sodium hyaluronate 0.01 Tranexamic acid (Nippon Seika) 2.0 Carbomer 0.06 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were measured into separate containers. Part B was stirred with a paddle at 70°C, and then Part A was added. After cooling, pre-mixed Part C was added to create a homogeneous liquid.

[0077] Example 28: Transparent Gel Component Amount (% by weight) ------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Mannosylerythritol Lipid (MEL-B) 1.0 Ceramide 3 0.4 Catechin 0.02 DPG 5.0 1,2-Pentanediol 3.0 Part B Purified water 50.0 C part PPG-6 Decyltetradeceth-30 0.2 PEG-30 Phytosterol 0.3 PEG-4M 0.2 Methylgluceth-10 1.0 Pyridoxine hydrochloride 0.05 Ethylhexylglycerin 0.2 Phenoxyethanol 0.4 Tranexamic acid (Nippon Seika) 2.0 Tremoist-TP (Nippon Fine Chemical) 0.01 Hydrolyzed collagen 0.01 Purified water, in an amount that totals 100. (Dimethyltaurate Ammonium Acrylate / Vinylpyrrolidone) Copolymer 0.05 (Acrylates / C10-30 Alkyl Acrylate) Crosspolymer 0.15 Arginine 0.25 -------------------------------------- (Preparation method) Parts A and B were measured into separate containers. Part B was stirred with a paddle at 80°C, and then Part A was added. After cooling, pre-mixed Part C was added to create a homogeneous liquid.

[0078] Example 29: Scalp Lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 2.0 Mannosylerythritol Lipid (MEL-B) 1.0 Ceramide 6 0.3 DPG 5.0 BG 5.0 Part B Purified water 40.0 C part Maltitol solution 0.5 PEG-60 Hydrogenated Castor Oil 0.3 Ethanol 10.0 Neosolue-AquaS (Nippon Fine Chemical) 2.0 Betaine 0.2 Hydroxypropyl chitosan solution 0.05 Carrot extract 0.1 Pyridoxine hydrochloride 0.05 Panthenol 0.1 Dipotassium glycyrrhizinate 0.1 Phenoxyethanol 0.3 Purified water, in an amount that totals 100. -------------------------------------- (Preparation method) Parts A and B were measured into separate containers. Part B was stirred with a paddle at 80°C, and then Part A was added. After cooling, pre-mixed Part C was added to create a homogeneous liquid.

[0079] Example 30: Scalp Lotion Component Amount (% by weight) ------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 2.0 Mannosylerythritol Lipid (MEL-B) 2.0 Ceramide 1 0.2 Ellagic acid 0.05 1,2-Hexanediol 5.0 BG 4.0 Part B Purified water 40.0 C part Neosolue-Aqulio (Nippon Seika) 1.0 Tocopherol acetate 0.05 Menthol 0.1 Betaine 0.2 Swertia japonica extract 0.1 Stephania tetrandra root extract 0.003 Hinokitiol 0.1 PCA-Na 0.1 Carbomer 0.01 K hydroxide 0.01 Pentasodium pentetate 0.05 Phenoxyethanol 0.4 Purified water, in an amount that totals 100. ------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and part A was added to part B while stirring with a homomixer (7000 rpm). After cooling, part C, which had been mixed beforehand, was added to create a homogeneous liquid.

[0080] Example 31: Hair growth agent Component Amount (% by weight) ------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 0.5 Mannosylerythritol Lipid (MEL-B) 1.0 Ceramide 3 0.2 1,2-Pentanediol 5.0 Glycerin 2.0 Part B Polyglyceryl-10 myristate 4.0 PEG-60 Hydrogenated Castor Oil 0.3 Purified water 40.0 C part Betaine 0.5 Ethanol 20.0 Menthol 0.1 Neosolue-AquaS (Nippon Fine Chemical) 2.0 Orange oil 0.05 Panthenyl ethyl ether 0.2 Carrot extract 1.0 Sophora angustifolia extract 2.0 Chlorella extract 1.0 Trehalose 0.5 Nicotinamide 1.0 Piroctone olamine 0.1 Dipotassium glycyrrhizinate 0.1 Purified water, in an amount that totals 100. ------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and part A was added to part B while stirring with a homomixer (7000 rpm). After cooling, part C, which had been mixed beforehand, was added to create a homogeneous liquid.

[0081] Example 32: Hair growth agent Component Amount (% by weight) ------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Mannosylerythritol lipid (MEL-B) 0.3 Ceramide 6 0.1 Polyglyceryl-10 palmitate 0.4 Polyglyceryl-10 laurate 0.2 Part B Purified water 45.0 C part Neosolue-Aqulio (Nippon Seika) 0.5 DPG 2.0 Lactic acid 0.1 Tremoist-TP (Nippon Fine Chemical) 0.01 Ethanol 10.0 Menthol 0.1 Menthyl glyceryl ether 0.15 Panthenyl ethyl ether 0.2 Camphor 0.1 Cordyceps sinensis extract 1.0 Swertia japonica extract 1.0 Loquat leaf extract 1.0 Hydrolyzed hyaluronic acid 0.02 Sodium cyclic lysophosphatidic acid 0.001 Chili pepper extract 0.01 Betaine 0.3 Trehalose 0.2 Cymene-5-ol 0.1 Tocopherol acetate 0.05 β-Glycyrrhetinic acid 0.05 Purified water, in an amount that totals 100. ------------------------------------- (Preparation method) Parts A and B were heated to 70°C each, and part A was added to part B while stirring with a homomixer (7000 rpm). After cooling, part C, which had been mixed beforehand, was added to create a homogeneous liquid.

[0082] Example 33: Whitening Emulsion Component Amount (% by weight) -------------------------------------- Part A Plandool-DP (Nippon Fine Chemical) 1.0 Cetyl ethylhexanoate (Nippon Seika) 5.0 Cetanol 1.2 Dimethicone 100cs 1.0 Myristyl alcohol 2.0 Oleyl alcohol 1.0 Part B Stearoxyhydroxypropylmethylcellulose 0.1 Xanthan gum 0.1 Sodium citrate (appropriate amount) 3-O-ethyl ascorbic acid (Nippon Seika) 0.5 Tranexamic acid (Nippon Seika) 2.0 Nicotinamide 5.0 Phenoxyethanol 0.2 Purified water 10.0 C part Phytocompo-PP (Nippon Fine Chemical) 1.0 Glycerin 5.0 D part Methylparaben 0.15 Phytic acid 0.5 Purified water, in an amount that totals 100. Part E Aqueous dispersion composition of Example 4 40.0 -------------------------------------- (Preparation method) Parts A and D were heated to approximately 70°C and dissolved uniformly. Part C was heated to approximately 70°C and dispersed uniformly. Part A was added to Part C while stirring with a homodisperser, and then Part D was added. After cooling, Parts B and E were added at approximately 40°C and stirred to mix uniformly.

[0083] Example 34 Emulsion Component Amount (% by weight) ------------------------------------- Part A Glycerin 3.0 Diglycerin 1.0 BG 5.0 Phytocompo-C (Nippon Fine Chemical) 1.5 Part B Triethylhexanoin (Nippon Seika) 3.0 LUSPLAN SR-DM4 (Nippon Seika) 0.5 Hydrogenated polyisobutene 3.5 Isododecane 1.5 Cetostearyl alcohol 1.0 Alkali alcohol 0.1 Jojoba alcohol 3.0 Kimyl alcohol 0.3 Cerakill alcohol 0.1 Hexyldecanol 0.5 C part (Hydroxyethyl Acrylate / Sodium Acryloyldimethyl Taurate) Copolymer 0.2 Tremoist-TP (Nippon Seika) 0.03 Carbomer 0.1 Potassium hydroxide 0.2 Purified water 30.0 Part D Neosolue-AquaS (Nippon Seika) 0.5 Polyquaternium-51 1.0 Tranexamic acid (Nippon Seika) 2.0 Nicotinamide 5.0 Methylparaben 0.15 Purified water, amount to make a total of 100 Part E Aqueous dispersion composition of Example 2 10.0 ------------------------------------- (Preparation method) Parts A, B, and D were each mixed, heated to about 70 °C, and uniformly dissolved and dispersed. Part C was mixed and stirred to form a viscous liquid. After adding Part B while stirring Part A with a homodisper, Part D was further added and emulsified. After cooling, Parts C and E were added at about 40 °C and stirred.

[0084] [[ID=​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​Cetyl PG hydroxyethyl palmitamide 0.05 Dipentaerythrityl hexahydroxystearate 1.0 C part Carbomer 0.1 K hydroxide 0.07 Xanthan gum 0.1 Purified water 10.0 D part Phenoxyethanol 0.4 Ethylhexylglycerin 0.2 Methylparaben 0.05 Nicotinamide 5.0 Purified water, in an amount that totals 100. Part E Aqueous dispersion composition of Example 6 10.0 ------------------------------------- (Preparation method) Parts A, B, and D were mixed separately and heated to approximately 70°C to uniformly dissolve and disperse. Part C was mixed in and stirred to form a viscous liquid. Part B was added to Part A while stirring in a homodisperser, and then Part D was added and emulsified. After cooling, Parts C and E were added at approximately 40°C and stirred.

[0085] Example 36: Skincare Cream Component Amount (% by weight) ------------------------------------- Part A Squalane 10.0 Stearic acid 1.0 Plandool-ISS (Nippon Fine Chemical) 1.0 Macadamia nut oil 3.0 Hydrogenated rapeseed alcohol 2.0 Cetearyl olivate 1.0 Olive oil fatty acid sorbitan 0.8 Polyglyceryl-10 oleate 1.0 Part B Acrylic acid / alkyl methacrylate copolymer 0.1 Potassium Hydroxide 0.07 (Acryloyldimethyltaurine Ammonium / Behenyl Methacrylate-25) Crosspolymer 0.2 Tremoist-SL (Nippon Seika) 1.0 Purified Water 20.0 Hydrolyzed Poly-γ-Glutamic Acid Potassium 0.1 Sodium Polyglutamate 0.1 Oligopeptide-24 0.05 Part C PrimeLipid-PI (Nippon Seika) 1.0 PEG-8 5.0 PEG-2M 2.0 Glyceryl Caprylate 0.8 Purified Water in an amount to total 100 Part D The aqueous dispersion composition of Example 5 15.0 ------------------------------------- (Preparation Method) Parts A and C were each mixed, heated to about 70°C, and uniformly dissolved and dispersed. Part B was mixed and stirred to form a viscous liquid. While stirring Part C with a homomixer, Part A was added and emulsified. After cooling, Parts B and D were added at about 40°C and stirred. <000098​​​​​​​​​​​​​​​​​​​​​​​​​​​Behenyl alcohol 1.5 Sorbitan stearate 1.0 Polyglyceryl-10 laurate 1.0 PEG-60 Glyceryl Isostearate 1.0 Methyl glucose sesquistearate 1.5 Part B Xanthan gum 0.1 Hydroxyethylcellulose 0.1 Crystalline cellulose powder 0.3 Stearoxyhydroxypropylmethylcellulose 0.1 Tranexamic acid (Nippon Seika) 2.0 Purified water 20.0 C part Glycerin 8.0 DPG 5.0 Sorbitol 2.0 Neosolue-Aqulio (Nippon Seika) 1.0 Methylparaben 0.15 Purified water, in an amount that totals 100. D part Aqueous dispersion composition of Example 9 10.0 ------------------------------------- (Preparation method) Parts A and C were mixed separately and heated to approximately 70°C to dissolve and disperse uniformly. Part B was mixed and stirred to form a viscous liquid. Part C was added to Part A while stirring with a homomixer and emulsified. After cooling, Parts B and D were added at approximately 40°C and stirred.

[0087] Example 38: Skincare Cream Component Amount (% by weight) ------------------------------------- Part A Glycerin 12.0 BG 3.0 Phytocompo-PP (Nippon Fine Chemical) 2.5 Part B Olive fruit oil 3.0 Olive oil 1.5 Shea butter 1.0 Pentaerythrityl tetraethylhexanoate (Nippon Seika) 3.0 Sucrose stearate 0.8 Cetearyl glucoside 1.2 Behenyl alcohol 1.5 Ascorbyl tetrahexyldecanoate 7.0 Isopropyl lauroyl sarcosinate 2.0 Hydrogenated Cocoglycerides 3.0 Cetanol 2.5 Sorbitan stearate 0.8 C part Xanthan gum 0.05 Tremoist-SL (Nippon Seika) 1.0 Tuberose polysaccharide 0.01 Water-soluble collagen 0.05 Hydrolyzed collagen 0.5 Sodium pyrosulfite 0.03 Arbutin (Nippon Seika) 1.0 Tranexamic acid (Nippon Seika) 1.0 Purified water 10.0 D part Neosolue-Aqulio (Nippon Seika) 1.0 Propanediol 3.0 Methylparaben 0.1 Glyceryl caprylate 1.0 Purified water, in an amount that totals 100. Part E Aqueous dispersion composition of Example 11 15.0 ------------------------------------- (Preparation method) Parts A, B, and D were mixed separately and heated to approximately 70°C to dissolve and disperse uniformly. Part C was mixed in and stirred to form a viscous liquid. Part B was added to Part A while stirring in a homodisperser, and then Part D was added and emulsified. After cooling, Parts C and E were added at approximately 50°C and stirred.

[0088] Example 39: Skincare Cream Component Amount (% by weight) ------------------------------------ Part A Neosolue-DiSM (Nippon Seika) 5.0 Jojoba oil 2.0 Plandool-H (Nippon Fine Chemical) 1.0 Neosolue-MCT (Nippon Seika) 3.0 LUSPLAN DD-DHR (Nippon Seika) 1.0 Plandool-SUN (Nippon Fine Chemical) 1.3 Propylene glycol stearate 0.6 Squalane 3.0 Behenyl alcohol 2.0 Liquid isoparaffin 0.5 Carnauba wax 0.3 Corn oil 0.3 Rapeseed oil 1.0 Sunflower oil 1.0 wheat germ oil 1.0 Flaxseed oil 0.1 Cottonseed oil 0.1 Soybean oil 0.1 Shea butter 0.5 Stigmasterol 1.0 Stigma 1.0 Dihydrocholesterol 0.1 Lanosterol 0.1 Dihydrolanosterol 0.1 Cholesteryl nonanoate 0.1 Cholesteryl stearate 0.1 Cholesteryl isostearate 1.0 Cholesteryl oleate 0.1 12-Cholesteryl hydroxystearate 0.1 Long-chain branched fatty acid cholesteryl 0.3 Octyldodecyl myristate 1.0 Octyldodecyl isostearate 1.0 Dimer dilinoleic acid hydrogenated castor oil 1.0 Hydroxyalkyl dimer dilinoleyl ether 1.0 Tetra(hydroxystearic acid / isostearate)dipentaerythrityl 0.5 Rice bran oil fatty acid phytosteryl 0.5 Phenylentrimethicone 1.0 Diphenyldimethicone 1.0 Methylhydrogenpolysiloxane 1.0 Polyglyceryl-3 polydimethylsiloxyethyl dimethicone 0.5 Dimethicone 50cs 0.3 Polyoxyethylene methylpolysiloxane copolymer 1.0 Tocopherol ferulate 0.1 Tocopherol phosphate 0.1 Tocotrienol 0.1 Tannin 0.01 Sesamin 0.01 Proanthocyanidin 0.01 Glabridin 0.01 Grabren 0.01 Liquiiritin 0.01 Isoliqueritin 0.01 Lactoferrin 0.01 Gingerol 0.01 Gingerol 0.01 Part B (Acryloyldimethyltaurine / Beheneth-25 Methacrylate) Copolymer 0.2 Crystalline cellulose 0.1 Gellan gum 0.1 Carboxyvinyl polymer 0.1 K hydroxide 0.08 Purified water 20.0 C part Phytocompo-PP (Nippon Fine Chemical) 1.0 Polyglyceryl-10 stearate 0.5 Glycerin 7.0 DPG 7.0 D part Citric acid 0.07 Sodium citrate (appropriate amount) EDTA-2Na 0.05 Pentasodium pentetate 0.03 Phenoxyethanol 0.4 Purified water, in an amount that totals 100. Part E Aqueous dispersion composition of Example 12 5.0 -------------------------------------- (Preparation method) Part A was mixed and heated to approximately 70°C to dissolve uniformly. Part B was mixed and stirred to form a viscous liquid. Part C was mixed and heated to approximately 70°C to disperse uniformly. Part D was mixed and heated to approximately 70°C to dissolve uniformly. Part A was added to Part C while stirring in a homogenizer, and then Part D was added to emulsify. After cooling, Parts B and E were added at approximately 50°C and stirred.

[0089] Example 40: Skincare Cream Component Amount (% by weight) -------------------------------------- Part A Plandool-G (Nippon Fine Chemical) 1.0 Neosolue-Aqulio (Nippon Seika) 1.5 Diethylhexyl sebacate (Nippon Seika) 8.0 Diisopropyl sebacate (Nippon Seika) 2.0 Theobroma grandiflorum seed butter 3.0 Batyl isostearate 2.0 Shea butter 3.0 (Dimethicone / Vinyl Dimethicone) Crosspolymer 0.3 (Vinyl dimethicone / Lauryl dimethicone) crosspolymer 0.5 (Dimethicone / PEG-10 / 15) Crosspolymer 0.5 (PEG-15 / Lauryl Dimethicone) Crosspolymer 0.2 (Alkyl acrylate / dimethicone) copolymer 0.1 Isostearyl pivalate 0.1 Pentaerythrityl tetraethylhexanoate (Nippon Seika) 0.1 Stearyl alcohol 3.5 Cetanol 1.3 Coconut fatty acid sucrose 1.0 Polyglyceryl-3 methylglucose distearate 0.8 Triglycerides (C10-18) 3.0 Squalane 3.0 Dimethicone 100cs 1.0 Tocopherol 0.1 Ascorbyl tetrahexyldecanoate 8.0 Tocopheryl ascorbyl phosphate 2.0 Placenta extract 1.0 Oryzanol 0.3 Phytosphingosine 0.0001 Ubiquinone 0.03 Carotene 0.05 Lycopene 0.01 Astaxanthin 0.01 Lutein 0.01 Fullerene 0.001 Peanut oil 0.1 Rice bran oil 1.0 Hydrogenated castor oil 0.3 Jojoba oil 2.0 Orange roughy oil 1.0 Liquid lanolin (Nippon Seika) 1.0 Lanolin (Nippon Seika) 1.0 Polyoxyethylene lanolin 1.0 Lanolin alcohol (Nippon Seika) 0.3 Alcoholic lanolin acetate 0.1 Cholesteryl acetate 0.1 Octocrylene 0.5 Sorbitan sesquistearate 1.2 Part B Tremoist-TP (Nippon Fine Chemical) 0.05 Water-soluble collagen 0.05 Hydrolyzed collagen 0.5 Glutathione 0.3 Arbutin (Nippon Seika) 3.0 Nicotinamide 5.0 C part Propanediol 10.0 PPG-9 Diglyceryl 2.0 Diglycerin 1.0 Sodium pyrosulfite 0.1 Imidazolinium urea 0.1 Polyvinylpyrrolidone 0.1 Pullulan 0.1 Polyvinyl alcohol 0.1 Dehydroacetic acid 0.1 PEG-32 1.0 Polyglycerin-10 1.0 Pentasodium pentetate 0.05 Phenoxyethanol 0.4 1,2-Pentanediol 2.0 Succinic acid 0.05 Sodium succinate (appropriate amount) Purified water, in an amount that totals 100. D part Aqueous dispersion composition of Example 7 5.0 -------------------------------------- (Preparation method) Part A was heated to approximately 70°C and dissolved uniformly. Part B was homogenized using some purified water. Part C was heated to approximately 70°C and dispersed. Part A was gradually added to Part C while stirring with a homomixer at approximately 70°C and emulsified. After cooling to approximately 40°C, Parts B and D were added and mixed uniformly, and the pH was adjusted to 6.5-7.0 with sodium succinate.

[0090] Example 41 Emulsion Component Amount (% by weight) -------------------------------- Part A Phytocompo-SP (Nippon Fine Chemical) 10.0 Lysolecithin (Nippon Seika) 0.1 Part B Squalane 4.0 Neosolue-MCT (Nippon Seika) 4.0 α-olefin oligomer 2.5 Dimethicone 5cs 3.5 Cetanol 1.5 Glyceryl stearate 1.0 C part Hydroxyproline 0.05 Citric acid 0.01 Sodium citrate 0.09 Arbutin (Nippon Seika) 3.0 Phenoxyethanol 0.3 Methylparaben 0.1 Acrylic acid / alkyl methacrylate copolymer 0.1 K hydroxide 0.1 Purified water, in an amount that totals 100. D part Aqueous dispersion composition of Example 12 40.0 ----------------------------------- (Preparation method) Parts A, B, and C were each taken and heated to approximately 70°C, then mixed uniformly. Part B was gradually added to part A while stirring with a homodisperser, and then part C was added and emulsified. After that, it was cooled to approximately 40°C, and part D was added.

[0091] Example 42: Leave-in hair treatment Component Amount (% by weight) ------------------------------------- Part A Polyquaternium-37 2.0 Squalane 2.0 PPG-3 Caprylyl Ether 2.0 Microcrystalline wax 0.1 Lanolin alcohol 0.2 Montan Wax 0.1 Polyethylene wax 0.1 Woodrow 0.2 Ceresin 0.1 PG dicaprate 1.0 Almond oil 0.5 Ethylhexyl ethylhexanoate 1.0 Candelilla wax extract 0.1 Octyldodecyl erucate 4.5 Tocopherol acetate 0.02 Elcalactone MCT (Nippon Seika) 2.0 Dipentaerythrityl tripolyhydroxystearate 1.5 PPG-5 Phytosteryl 0.5 Glycerin 4.0 Sorbitol 2.0 Phenoxyethanol 0.5 Part B Hydrolyzed hyaluronic acid 0.1 Panthenol 0.1 Hydroxypropyltrimonium hyaluronate 0.01 Polyquaternium-11 0.2 Glycosyltrehalose 0.1 Glyceryl glucoside 0.3 Arginine 0.1 C part Purified water, in an amount that totals 100. Hydroxypropyl starch phosphate 1.0 D part Aqueous dispersion composition of Example 4 5.0 -------------------------------------- (Preparation method) Part C was uniformly dispersed and heated to approximately 80°C. Next, Part A was heated to approximately 80°C and dissolved. Part A was added to Part C while stirring, and after uniform mixing, it was cooled to approximately 40°C. Then, Parts B and D were added and uniformly mixed.

[0092] Example 43: Leave-in scalp / hair treatment Component Amount (% by weight) -------------------------------------- Part A Neosolue-Aqulio (Nippon Seika) 1.0 Ethanol 40.0 Glycyrrhetinic acid 0.02 Elcalactone DES (Nippon Seika) 1.5 PEG / PPG-20 / 20 Dimethicone 0.2 PEG-12 Dimethicone 0.4 Hydrogenated retinol 0.1 Pyridoxine trishexyldecanoate 0.05 Bisglyceryl ascorbate 0.3 Hexyl 3-glyceryl ascorbate 0.3 Part B Triethanolamine 0.1 Purified water, in an amount that totals 100. (Acrylates / C10-30 Alkyl Acrylate) Crosspolymer 0.4 Carbomer 0.05 Tremoist-SL (Nippon Seika) 1.0 (Acryloyldimethyltaurate Ammonium / VP) Copolymer 0.05 (Acryloyldimethyltaurate ammonium / Beheneth-25 Methacrylate Crosspolymer 0.1 Hydroxypropyl chitosan 0.1 Methylparaben 0.1 Phenoxyethanol 0.2 C part 3-O-ethyl ascorbic acid (Nippon Seika) 0.3 Nicotinamide 0.3 Pyridoxine hydrochloride 0.1 Caffeine 0.1 Glucosyltrehalose 0.1 Purified water 10.0 D part Hydrogenated lecithin (PC content 50-75%) 0.8 Mannosylerythritol lipid (MEL-B) 0.5 Ceramide 6 0.2 1,2-Pentanediol 3.0 BG 4.0 Part E Polyglyceryl-10 Dimyristate 1.4 Purified water 20.0 -------------------------------------- (Preparation method) Part A was heated to approximately 50°C and dissolved. Next, Part B was uniformly dispersed to form a viscous liquid. Parts D and E were each heated to 70°C, and Part D was added to Part E while stirring with a homomixer (4000 rpm), and then cooled (Part F). Part A was added to Part B while stirring and mixed uniformly. Then Part C was added and mixed uniformly. After cooling, Part F was added and mixed uniformly.

[0093] Example 44: Leave-on hair treatment Component Amount (% by weight) -------------------------------- Part A Neosolue-Aqulio (Nippon Seika) 2.0 Cetanol 3.8 Caprylyl glucoside (50%) 1.5 Glycerin 4.0 Phenoxyethanol 0.5 Part B Ethanol 5.0 C part Polyquaternium-6 0.6 Polyquaternium-7 0.4 Polyquaternium-39 0.5 Purified water, in an amount that totals 100. D part Aqueous dispersion composition of Example 3 10.0 -------------------------------- (Preparation method) Part C was heated to approximately 80°C and dissolved. Next, Part A was heated to approximately 80°C and dissolved. Part A was added to Part C while stirring, and after uniform mixing, it was cooled to approximately 40°C. Then, Parts B and D were added and uniformly mixed.

[0094] Example 45: Liquid Foundation Component Amount (% by weight) --------------------------------- Part A PrimeLipid-PI (Nippon Fine Chemical) 1.0 Octyltriazone 1.5 Ethylhexyl methoxycinnamate 1.0 Quaternium-18 hectorite 0.5 Part B Cyclomethicone 25.0 Polyether-modified silicone mixture 5.0 (Manufactured by Toray Dow Corning Silicone Co., Ltd., BY22-008M) Polyglyceryl-2 isostearate 1.0 Titanium oxide / iron oxide mixture 12.5 Mica 6.0 C part Glycerin 5.0 Neosolue-AquaS (Nippon Fine Chemical) 0.4 Methylparaben 0.2 Tranexamic acid (Nippon Seika) 2.0 Purified water, in an amount that totals 100. D part Aqueous dispersion composition of Example 10 5.0 --------------------------------- (Preparation method) Part A was heated to approximately 80°C and thoroughly dispersed. Part B, also heated to approximately 80°C, was added to this, followed by Part C, which was further heated to approximately 80°C. The mixture was then emulsified using a homogenizer. After cooling to room temperature, Part D was added and the mixture was stirred.

[0095] Example 46 Foundation Component Amount (% by weight) ------------------------------------ Part A Isododecane 10.0 Neosolue-MCT (Nippon Seika) 4.0 Ethylhexyl Methoxycinnamate 3.0 Plandool-SUN (Nippon Fine Chemical) 1.0 Plandool-LG2 (Nippon Seika) 1.0 Plandool-LG4 (Nippon Seika) 1.0 Vaseline 1.0 Isotridecyl isononanoate 2.0 Ascorbyl tetrahexyldecanoate 0.1 Dextrin palmitate 0.3 Sorbitan isostearate 1.5 Tribehenin 0.5 (butyl acrylate / glycol dimethacrylate) crosspolymer, silica, (Methyl methacrylate / glycol dimethacrylate) crosspolymer mixture 2.0 Boron nitride 1.0 Polysorbate 20 2.0 PEG-60 Hydrogenated Castor Oil 1.0 Disteardimonium hectorite (20%) 2.5 Polypropylsilsesquioxane and cyclopentasiloxane mixture 1.0 Mica 15.0 Talc 4.0 Zinc oxide 5.0 Titanium dioxide 10.0 Iron oxide 1.5 Part B Amount of water that totals 100 DPG 4.0 Maltitol (75% solution) 1.0 Neosolue-AquaS (Nippon Fine Chemical) 0.4 Sodium chloride 1.0 BG 1.0 Tremoist-SL (Nippon Seika) 1.0 Ethanol 0.5 Phenoxyethanol 0.3 C part Aqueous dispersion composition of Example 16 4.0 ------------------------------------ (Preparation method) Part A was heated to approximately 70°C and stirred thoroughly to ensure uniform dispersion. Part B was heated to approximately 70°C and made uniform, then Part B was added to Part A, stirred at approximately 70°C to emulsify, and cooled to approximately 40°C. Part C was added and stirred.

[0096] Example 47: Sunscreen Cosmetic Component Amount (% by weight) ----------------------------------- Part A FINEX-33W (Sakai Chemical Industry) 5.0 STR-100W (Sakai Chemical Industry) 5.0 Purified water, in an amount that totals 100. BG 7.0 Disodium edetate 0.05 Triethanolamine 1.0 Part B Oxybenzone 3.0 Octyl paramethoxycinnamate 5.0 t-Butylmethoxybenzoylmethane 3.0 Diethylhexyl sebacate (Nippon Seika) 8.0 Plandool-H (Nippon Fine Chemical) 2.0 Plandool-SUN (Nippon Fine Chemical) 2.0 Plandool-MAS (Nippon Seika) 0.1 Plandool-LG1 (Nippon Seika) 0.1 Plandool-LG2 (Nippon Seika) 0.1 Plandool-LG3 (Nippon Seika) 0.1 Plandool-LG4 (Nippon Seika) 0.1 LUSPLAN PI-DA (Nippon Fine Chemical) 3.0 Cetyl ethylhexanoate (Nippon Seika) 3.0 Diisopropyl sebacate (Nippon Seika) 5.0 Dimethicone 2cs 5.0 Sucrose stearate 1.5 Polyglyceryl-10 stearate 2.0 Stearyl alcohol 3.0 Batyl alcohol 1.0 Stearic acid 3.0 Glyceryl monostearate 3.0 Ethyl polyacrylate 1.0 Phenoxyethanol 0.5 C part Aqueous dispersion composition of Example 14 10.0 ----------------------------------- (Preparation method) Part A was heated to approximately 80°C and thoroughly dispersed. Part B, also heated to approximately 80°C, was added to this and emulsified using a homogenizer. After cooling to room temperature, Part C was added and stirred.

[0097] Example 48: Sunscreen Cosmetic Component Amount (% by weight) ----------------------------------- Part A BG 10.0 Glycerin 9.0 Phytocompo-PP (Nippon Fine Chemical) 1.0 Octocrylene 4.0 Octyl salicylate 4.0 Diethylamino hydroxybenzoyl hexyl benzoate 2.25 t-Butyl methoxydibenzoylmethane 1.0 Diethylhexyl sebacate (Nippon Seika) 3.0 Pentaerythrityl tetraethylhexanoate (Nippon Seika) 2.0 Dimethicone 1.5 Diisopropyl sebacate (Nippon Seika) 1.0 Behenyl alcohol 2.0 Cetearyl alcohol 2.0 Plandool-MAS (Nippon Seika) 1.0 Tocopherol 0.05 Part B Neosolue-AquaS (Nippon Fine Chemical) 1.0 Methylparaben (appropriate amount) Amount of water that totals 100 C part Carbomer (2%) 5.0 Tremoist-SL (Nippon Seika) 10.0 DIS-AB-10W (Sakai Chemical Industry) 5.0 D part Aqueous dispersion composition of Example 13 30.0 ----------------------------------- (Preparation method) Parts A and B were heated and dissolved to approximately 70°C. Part B was gradually added to part A while stirring and emulsified. After cooling, parts C and D were mixed at 45°C.

[0098] Example 49: Serum Component Amount (mass%) ------------------------------------- Part A Glycerin 1.0 BG 4.0 Phytocompo-SP (Nippon Fine Chemical) 5.0 PG 3.0 Part B Diethylhexyl succinate (Nippon Seika) 4.0 LUSPLAN PI-DA (Nippon Fine Chemical) 0.1 C part Purified water, in an amount that totals 100. Methylparaben 0.1 Inulin-SC (Nippon Fine Chemical) 1.0 D part Carbomer (2%) KOH neutralized product 5.0 Tremoist-SL (Nippon Seika) 2.5 Ethanol 5.0 Phenoxyethanol 0.2 Part E Aqueous dispersion composition of Example 11 20.0 ------------------------------------- (Preparation method) Part A, which was uniformly dispersed, was mixed with Part B, which was uniformly dissolved at 80°C, while stirring. Then, Part C, which was heated to 80°C, was mixed in while stirring. After cooling, Parts D and E were added while stirring.

[0099] Example 50: Serum Component Amount (mass%) ------------------------------------- Part A Glycerin 1.0 BG 4.0 Phytocompo-SP (Nippon Fine Chemical) 5.0 PG 3.0 Part B Dimethicone (10cs) 2.0 C part Purified water, in an amount that totals 100. Inulin-SC (Nippon Fine Chemical) 5.0 D part Carbomer (2%) KOH neutralized product 5.0 Tremoist-SL (Nippon Seika) 2.5 Ethanol 5.0 Phenoxyethanol 0.2 Part E Aqueous dispersion composition of Example 10 20.0 ------------------------------------- (Preparation method) Part A, which was uniformly dispersed, was mixed with Part B, which was uniformly dissolved at 80°C, while stirring. Then, Part C, which was heated to 80°C, was mixed in while stirring. After cooling, Parts D and E were added while stirring.

[0100] Example 51 Cream Component Amount (mass%) ------------------------------------- Part A Phytocompo-SP (Nippon Fine Chemical) 5.0 Glycerin 10.0 BG 1.0 Pentylene glycol 2.0 Part B Squalane 7.0 Plandool-MAS (Nippon Seika) 5.0 Behenyl alcohol 3.0 Pentaerythrityl tetraethylhexanoate (Nippon Seika) 2.0 Cetearyl alcohol 1.5 Cetyl palmitate 1.5 Dimethicone (10cs) 0.5 Stearic acid 1.0 Tocopherol 0.1 C part Purified water, in an amount that totals 100. Inulin-SC (Nippon Fine Chemical) 1.0 Xanthan gum (2% aqueous solution) 3.0 Phenoxyethanol 0.5 D part Carbomer (2%) KOH neutralized product 7.0 Part E Aqueous dispersion composition of Example 4 20.0 ------------------------------------- (Preparation method) Part A, which was uniformly dispersed while being heated to 70°C, was mixed with Part B, which was uniformly dissolved at 70°C, while stirring. Then, Part C, which was heated to 70°C, was mixed in while stirring. After cooling, Parts D and E were added while stirring.

[0101] Example 52: Lotion Component Amount (mass%) ------------------------------------- Part A Purified water, in an amount that totals 100. Ethanol 9.0 Bis-PEG-18 methyl ether dimethyl silane 5.0 Inulin-SC (Nippon Fine Chemical) 1.0 1,2-Pentanediol 1.0 Phenoxyethanol 0.2 Appropriate amount of citric acid Sodium citrate (appropriate amount) Neosolue-AquaS (Nippon Fine Chemical) 1.0 Part B Acrylates copolymer 0.5 DPG 1.0 Purified water 5.0 Aqueous dispersion composition of Example 15 10.0 ------------------------------------- (Preparation method) Parts A and B were dissolved uniformly. Part B was added to part A and mixed until uniform.

[0102] Example 53: Lotion Component Amount (mass%) ------------------------------------- Part A PEG-40 Hydrogenated Castor Oil 0.30 Neosolue-DiSM (Nippon Seika) 0.20 BG 3.0 Glycerin 2.0 Part B Purified water, in an amount that totals 100. Inulin-SC (Nippon Fine Chemical) 1.0 Phenoxyethanol (appropriate amount) C part Tremoist-SL (Nippon Seika) 1.0 Carboxymethyldextran Na 0.02 (dimethyltaurate ammonium acrylate / vinylpyrrolidone) copolymer 0.05 D part Aqueous dispersion composition of Example 8 10.0 ------------------------------------- (Preparation method) Parts A and B were uniformly dissolved at approximately 80°C. Part B was gradually added to part A and stirred. After cooling, parts C and D were added and mixed until uniform.

[0103] Example 54: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Mannosylerythritol lipid (MEL-B) 0.5 Ubiquinone 0.2 Tocopherol 0.02 BG 10.0 Part B Purified water, in an amount that totals 100. C part Neosolue-Aqulio (Nippon Seika) 1.0 Tremoist-TP (Nippon Fine Chemical) 0.1 EDTA-2Na 0.05 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Parts A and B were heated to approximately 80°C, and then mixed together while stirring. After cooling, part C was added to create a homogeneous liquid.

[0104] Example 55: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 1.0 Mannosylerythritol lipid (MEL-B) 0.5 Oryzanol 0.3 BG 5.0 Part B Purified water, in an amount that totals 100. C part Neosolue-Aqulio (Nippon Seika) 1.0 Tremoist-TP (Nippon Fine Chemical) 0.1 EDTA-2Na 0.05 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Parts A and B were heated to approximately 80°C, and then mixed together while stirring. After cooling, part C was added to create a homogeneous liquid.

[0105] Example 56: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 1.0 Mannosylerythritol Lipid (MEL-B) 1.0 Lutein 0.5 BG 5.0 Part B Purified water, in an amount that totals 100. C part Neosolue-Aqulio (Nippon Seika) 1.0 Tremoist-TP (Nippon Fine Chemical) 0.1 EDTA-2Na 0.05 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Parts A and B were heated to approximately 80°C, and then mixed together while stirring. After cooling, part C was added to create a homogeneous liquid.

[0106] Example 57: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Mannosylerythritol Lipid (MEL-B) 1.0 Astaxanthin 0.2 BG 5.0 1,2-Pentanediol 3.0 Part B Purified water, in an amount that totals 100. C part Neosolue-Aqulio (Nippon Seika) 1.0 Tremoist-TP (Nippon Fine Chemical) 0.1 EDTA-2Na 0.05 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Parts A and B were heated to approximately 80°C, and then mixed together while stirring. After cooling, part C was added to create a homogeneous liquid.

[0107] Example 58: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Mannosylerythritol Lipid (MEL-B) 1.0 Thioctic acid 0.5 BG 5.0 1,2-Pentanediol 3.0 Part B Purified water, in an amount that totals 100. C part Neosolue-Aqulio (Nippon Seika) 1.0 Tremoist-TP (Nippon Fine Chemical) 0.1 EDTA-2Na 0.05 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Parts A and B were heated to approximately 80°C, and then mixed together while stirring. After cooling, part C was added to create a homogeneous liquid.

[0108] Example 59: Moisturizing lotion Component Amount (% by weight) -------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 0.5 Mannosylerythritol Lipid (MEL-B) 1.0 Ferulic acid 0.5 BG 5.0 1,2-Pentanediol 3.0 Part B Purified water, in an amount that totals 100. C part Neosolue-Aqulio (Nippon Seika) 1.0 Tremoist-TP (Nippon Fine Chemical) 0.1 EDTA-2Na 0.05 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Parts A and B were heated to approximately 80°C, and then mixed together while stirring. After cooling, part C was added to create a homogeneous liquid.

[0109] Example 60 Cream Component Amount (mass%) ------------------------------------- Part A Phytocompo-SP (Nippon Fine Chemical) 5.0 Glycerin 10.0 BG 1.0 Pentylene glycol 2.0 Part B Squalane 7.0 Plandool-MAS (Nippon Seika) 5.0 Behenyl alcohol 3.0 Pentaerythrityl tetraethylhexanoate (Nippon Seika) 2.0 Cetearyl alcohol 1.5 Cetyl palmitate 1.5 Dimethicone (10cs) 0.5 Stearic acid 1.0 Tocopherol 0.1 C part Purified water, in an amount that totals 100. Phenoxyethanol 0.5 D part Carbomer (2%) KOH neutralized product 7.0 Part E Hydrogenated lecithin (PC content 76-99%) 1.0 Mannosylerythritol Lipid (MEL-B) 1.0 Ceramide 6 0.5 Curcumin 0.1 Cyanocobalamin 0.001 BG 10.0 F part Purified water 20.0 ------------------------------------- (Preparation method) Sections E and F were heated to 70°C each. Section E was added to Section F while stirring with a homomixer (4000 rpm), and then cooled (Section G). Section A, which was uniformly dispersed while being heated to 70°C, was mixed with Section B, which was uniformly dissolved at 70°C, while stirring. Then, Section C, which was heated to 70°C, was mixed in while stirring. After cooling, Sections D and G were added while stirring.

[0110] Example 61 Cream Component Amount (mass%) ------------------------------------- Part A Phytocompo-SP (Nippon Fine Chemical) 5.0 Glycerin 10.0 BG 1.0 Pentylene glycol 2.0 Part B Squalane 7.0 Plandool-MAS (Nippon Seika) 5.0 Behenyl alcohol 3.0 Pentaerythrityl tetraethylhexanoate (Nippon Seika) 2.0 Cetearyl alcohol 1.5 Cetyl palmitate 1.5 Dimethicone (10cs) 0.5 Stearic acid 1.0 C part Purified water, in an amount that totals 100. Phenoxyethanol 0.5 D part Carbomer (2%) KOH neutralized product 7.0 Part E Hydrogenated lecithin (PC content 50-75%) 1.0 Mannosylerythritol Lipid (MEL-B) 1.0 Ceramide 6 0.5 Proanthocyanidin 0.1 BG 5.0 1,2-Pentanediol 3.0 F part Purified water 20.0 ------------------------------------- (Preparation method) Sections E and F were heated to 70°C each. Section E was added to Section F while stirring with a homomixer (4000 rpm), and then cooled (Section G). Section A, which was uniformly dispersed while being heated to 70°C, was mixed with Section B, which was uniformly dissolved at 70°C, while stirring. Then, Section C, which was heated to 70°C, was mixed in while stirring. After cooling, Sections D and G were added while stirring.

[0111] In the above formulation, the details of the ingredients listed under the product name are as follows: Plandool-H: Dimer dilinoleate (phytosteryl / isostearyl / cetyl / stearyl / behenyl) Plandool-G: Dimer dilinoleyl dimer dilinoleate bis(behenyl / isostearyl / phytosteryl) Plandool-DP: Bis-diglyceryl polyacyladipate-2 Plandool-ISS: Phytosteryl isostearate Plandool-SUN: Phytosteryl sunflower seed oil fatty acids Plandool-MAS: Macadamia nut oil fatty acid phytosteryl Plandool-LG1: Lauroyl glutamate di(phytosteryl / octyldodecyl / behenyl) Plandool-LG2: Lauroyl glutamate di(phytosteryl / octyldodecyl) Plandool-LG3: Lauroyl glutamate di(phytosteryl / octyldodecyl / behenyl) Plandool-LG4: Lauroyl glutamate di(phytosteryl / octyldodecyl / behenyl) 〇LUSPLAN PI-DA: Dimer dilinoleate di(isostearyl / phytosteryl) LUSPLAN DD-DHR: Dimer Dilinoleyl Hydrogenated Rosin Condensate LUSPLAN SR-DM4: Dimer dilinoleyl dimer dilinoleate, Caprylic / Capric triglyceride Neosolue-Aqulio: Bisethoxydiglycol Cyclohexanedicarboxylic Acid 〇Neosolue-AquaS: (Eicosanedioic acid / Tetradecanedioic acid) Polyglyceryl-10, Glycerin 〇Neosolue-DiSM: Diisostearyl malate Neosolue-MCT: ​​Caprylic / Capric Triglyceride 〇Phytocompo-PP: Hydrogenated lecithin, phytosterols Phytocompo-C: Hydrogenated lecithin, phytosterols, ceramide 2, ceramide 3, ceramide 6II 〇Phytocompo-SP: Hydrogenated lecithin, phytosterols, BG, glycerin 〇Elcalactone MCT: γ-Docosalactone, Caprylic / Capric Triglyceride 〇 Elcalactone DES: γ-docosalactone, diethyl sebacate Tremoist-TP: Tremella fuciformis polysaccharide 〇Tremoist-SL: Tremella fuciformis polysaccharide aqueous solution (1%) PrimeLipid-PI: Hydrogenated lecithin, phytosterols, lecithin, tocopherols STR-100W: Titanium dioxide, hydrated silica FINEX-33W: Zinc oxide, hydrated silica 〇DIS-AB-10W: Titanium dioxide, hydrated silica, hydrogen dimethicone, water, BG, PEG-9 dimethicone ○Inulin-SC: Inulin

Claims

1. An aqueous dispersion composition containing the following components (A) to (C), wherein the mass ratio of components (A1) to (A2) is 5:5 to 1:9, the content of component (A3) in component (A) is 1 to 36% by mass, and the content of component (B) is 2 times or more by mass relative to component (A). (A) Lipid composition consisting of the following components (A1) to (A3) (A1) Mannosylerythritol lipid represented by the following general formula (1) 【Chemistry 1】 (In the formula, R1 and R2 represent hydrogen or an aliphatic acyl group having 2 to 24 carbon atoms (however, they do not simultaneously take hydrogen). Also, R3 and R4 represent hydrogen or an acetyl group, and R5 represents hydrogen or an aliphatic acyl group having 2 to 24 carbon atoms.) (A2) Hydrogenated lecithin containing 40% by mass or more phosphatidylcholine (A3) One or more poorly soluble components selected from ceramides, sterols, carotenoids, lipoic acid, and coenzyme Q10. (B) Polyhydric alcohols (C) Water

2. The aqueous dispersion composition according to claim 1, characterized in that component (A3) is a ceramide.

3. The aqueous dispersion composition according to claim 2, characterized in that component (A) forms a lipid membrane structure in the aqueous dispersion composition.

4. A cosmetic composition containing the aqueous dispersion composition according to any one of claims 1 to 3.

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