Development of radiopharmaceutical extraction system using automatic control robot and extracting method

Abstract

The present disclosure relates to a system and method for extracting radiopharmaceuticals using an automatic control robot, comprising: an upper plate; a plurality of guide rails on the upper plate; a first drive module movably coupled to the plurality of guide rails in a first direction; a second drive module movably coupled to the first drive module in a second direction; a robot arm movably coupled to the second drive module in a third direction; a storage module disposed on the upper plate and housing a vacuum container; a radioactive material generating module disposed on the upper plate and generating a radioactive isotope; a radiation dose measuring module disposed on the upper plate and measuring the radiation dose of the radioactive isotope; and a labeling module disposed on the upper plate and combining the radioactive isotope and the radiopharmaceutical after the measurement by the radiation dose measuring module is completed.

Description

Technology Field

[0001] The present disclosure relates to a drug extraction system. More specifically, the present disclosure relates to a radiopharmaceutical extraction system and method utilizing an automatic control robot. Background Technology

[0002] Currently, the number of cancer patients in Korea is steadily increasing due to factors such as poor dietary habits, and diagnostic and therapeutic methods using radioisotopes are widely used as useful tests for the differential diagnosis, staging, recurrence evaluation, and assessment of treatment effectiveness for various types of cancer.

[0003] In this way, using imaging methods utilizing radioisotopes (such as SPECT-CT and PET-CT) allows for the early detection of microscopic cancer cells or tumor tissues measuring several millimeters that could not be detected by conventional methods, as well as enables treatment to proceed while verifying the presence of cancer metastasis and recurrence, and the effectiveness of anticancer drugs.

[0004] Meanwhile, since the process of producing radioactive isotope pharmaceuticals is performed directly by workers, there is a risk of radiation exposure to the workers. Prior art literature

[0005] Korean Registered Patent No. 10-1257764 (Registered April 18, 2013) The problem to be solved

[0006] The purpose of the embodiments disclosed in this disclosure is to provide a system and method for extracting radiopharmaceuticals using an automatic control robot.

[0007] The problems that this disclosure aims to solve are not limited to those mentioned above, and other unmentioned problems will be clearly understood by a person skilled in the art from the description below. means of solving the problem

[0008] A radiopharmaceutical extraction system utilizing an automatic control robot according to the present disclosure for achieving the aforementioned technical problem may include: an upper plate; a plurality of guide rails on the upper plate; a first driving module movably coupled to the plurality of guide rails in a first direction; a second driving module movably coupled to the first driving module in a second direction; a robot arm movably coupled to the second driving module in a third direction; a storage module disposed on the upper plate and housing a vacuum container; a radioactive material generating module disposed on the upper plate and generating a radioactive isotope; a radiation dose measuring module disposed on the upper plate and measuring the radiation dose of the radioactive isotope; and a labeling module disposed on the upper plate and combining the radioactive isotope and the radiopharmaceutical after the measurement from the radiation dose measuring module is completed.

[0009] Additionally, it may further include a lower plate positioned below the upper plate so as to face the upper plate.

[0010] In addition, it may further include a plurality of support columns disposed between the lower plate and the upper plate.

[0011] In addition, the first driving module may include a guide bar to which the second driving module is movably coupled.

[0012] In addition, the second drive module may include a guide bar to which the robot arm is movably coupled.

[0013] In addition, the plurality of guide rails may be arranged on the upper plate so as to face each other in the second direction.

[0014] In addition, the storage module, the radioactive material generation module, the radiation dose measurement module, and the label module may be positioned between the plurality of guide rails.

[0015] In addition, the robot arm can grasp the vacuum container by suction.

[0016] In addition, when the radiation dose of the radioactive isotope measured by the radiation dose measurement module is greater than or equal to a preset reference value, the radioactive isotope and the radiopharmaceutical can be combined by the labeling module.

[0017] In addition, a method for extracting a radiopharmaceutical using an automatic control robot according to the present disclosure for achieving the aforementioned technical objectives comprises the steps of: a robot arm grasping a vacuum container of a storage module and the robot arm grasping the vacuum container moving to a radioactive material generation module; the radioactive material generation module extracting a radioactive material and injecting the extracted radioactive material into the vacuum container; the robot arm moving the vacuum container containing the radioactive material to a radiation dose measurement module; the radiation dose measurement module measuring the radiation dose of the radioactive material injected into the vacuum container; when the measured radiation dose of the radioactive material is greater than or equal to a preset reference value, the robot arm moving the vacuum container containing the radioactive material to a labeling module; the labeling module combining the radioactive material and the radiopharmaceutical; and mixing the radioactive material and the radiopharmaceutical using a rotating plate, wherein when the measured radiation dose of the radioactive material is less than the reference value, the radioactive material generation module additionally generates radioactive material until the radiation dose of the radioactive material becomes greater than or equal to the reference value. Effects of the invention

[0018] According to the means for solving the problem described above in the present disclosure, the synthesis process of radiopharmaceuticals for labeling by accumulation mechanism on radioisotopes (e.g., technetium-99m) is automated, so the productivity and versatility of the radiopharmaceuticals are excellent.

[0019] In addition, according to one embodiment, quantitative production is possible during the production of radioactive isotopes and the synthesis of labeled pharmaceuticals.

[0020] In addition, according to one embodiment, a safe working environment can be provided because the worker is not exposed to a hazardous environment. For example, the problem of radiation exposure can be overcome by utilizing a robot-based automatic control system in a radioactive environment, such as the production environment of radiopharmaceuticals. Therefore, the radiation dose can be drastically reduced during the process of producing radioisotopes.

[0021] According to one embodiment, the production of radioisotopes, measurement of radiation dose, and the pre-processing of labeling and syringe formulation of radiopharmaceuticals can be carried out in an all-in-one manner.

[0022] The effects of the present disclosure are not limited to those mentioned above, and other unmentioned effects will be clearly understood by a person skilled in the art from the description below. Brief explanation of the drawing

[0023] FIG. 1 is a perspective view of a radiopharmaceutical extraction system utilizing an automatic control robot according to one embodiment. FIG. 2 is a perspective view of a radiopharmaceutical extraction system utilizing an automatic control robot from another viewpoint of FIG. 1. FIG. 3 is a top view of a radiopharmaceutical extraction system utilizing an automatic control robot of FIG. 1. FIG. 4 is a front view of a radiopharmaceutical extraction system utilizing an automatic control robot of FIG. 1. FIG. 5 is a side view of a radiopharmaceutical extraction system utilizing an automatic control robot of FIG. 1. FIG. 6, FIG. 7, FIG. 8, and FIG. 9 are drawings for explaining the movement of the robot arm of FIG. 1. FIG. 10 is a drawing for explaining the method of gripping a vacuum vessel by the robot arm of FIG. 1. FIG. 11 is a drawing for explaining the process of mixing the radioactive material generated from the radioactive material generation module of FIG. 1 with the radiopharmaceutical. FIG. 12 is a drawing for explaining the process of mixing the radioactive material and the radiopharmaceutical. FIG. 13 is a flowchart for explaining a radiopharmaceutical extraction method according to one embodiment. Specific details for implementing the invention

[0024] Throughout this disclosure, the same reference numerals denote the same components. This disclosure does not describe all elements of the embodiments, and general content in the art to which this disclosure pertains or content that overlaps between embodiments is omitted. The terms “part, module, component, block” as used in the specification may be implemented in software or hardware, and depending on the embodiments, a plurality of “parts, modules, components, blocks” may be implemented as a single component, or a single “part, module, component, block” may include a plurality of components. Throughout the specification, when a part is described as being “connected” to another part, this includes not only direct connection but also indirect connection, and indirect connection includes connection via a wireless communication network.

[0025] Furthermore, when it is stated that a part "includes" a certain component, this means that, unless specifically stated otherwise, it does not exclude other components but may include additional components.

[0026] Throughout the specification, when it is stated that a component is located "on" another component, this includes not only cases where a component is in contact with another component, but also cases where another component exists between the two components.

[0027] Terms such as "first," "second," etc., are used to distinguish one component from another, and the components are not limited by the aforementioned terms.

[0028] Singular expressions include plural expressions unless there is an obvious exception in the context.

[0029] In each step, identification codes are used for convenience of explanation and do not describe the order of the steps; the steps may be performed differently from the specified order unless a specific order is clearly indicated in the context.

[0030] The operating principles and embodiments of the present disclosure will be described below with reference to the attached drawings.

[0031] FIG. 1 is a perspective view of a radioactive drug extraction system (1000) utilizing an automatic control robot according to one embodiment, FIG. 2 is a perspective view of a radioactive drug extraction system (1000) utilizing an automatic control robot from another perspective of FIG. 1, FIG. 3 is a top view of a radioactive drug extraction system (1000) utilizing an automatic control robot of FIG. 1, FIG. 4 is a front view of a radioactive drug extraction system (1000) utilizing an automatic control robot of FIG. 1, and FIG. 5 is a side view of a radioactive drug extraction system (1000) utilizing an automatic control robot of FIG. 1.

[0032] A radioactive drug extraction system (1000) utilizing an automatic control robot according to one embodiment may include, as illustrated in FIGS. 1 to 5, a lower plate (710), an upper plate (720), a plurality of support columns (800), a plurality of guide rails (610), a first driving module (621), a second driving module (622), a robot arm (100), a storage module (200), a vacuum container (222; e.g., a vacuum vial), a radioactive material generating module (300; e.g., a generator), a radiation dose measuring module (400), and a labeling module (500).

[0033] The lower plate (710) may have a rectangular shape.

[0034] The upper plate (720) may be placed on the lower plate (710). For example, the upper plate (720) may be placed on the upper plate (720) facing the lower plate (710). The upper plate (720) may have a rectangular shape.

[0035] Multiple support columns (800) may be placed between the lower plate (710) and the upper plate (720). Multiple support columns (800) may be placed at each of the four corners of the lower plate (710). The lower plate (710) and the upper plate (720) may be spaced apart by the multiple support columns (800).

[0036] A plurality of guide rails (610) may be disposed on the upper plate (720). Each of the plurality of guide rails (610) may extend along a first direction (DR1). The plurality of guide rails (610) may each be disposed on the edges of the upper plate (720) facing each other in a second direction (DR2).

[0037] The first drive module (621) may be positioned on a plurality of guide rails (610). The first drive module (621) may be movably coupled to the plurality of guide rails (610). The first drive module (621) may move along the plurality of guide rails (610) in a first direction (DR1) and / or in the reverse direction of the first direction (DR1) (hereinafter, the first reverse direction). The first drive module (621) may extend along a second direction (DR2).

[0038] A second drive module (622) may be positioned on one side of a first drive module (621). The second drive module (622) may be coupled to a guide bar (621a) positioned on the side of the first drive module (621). For example, the second drive module (622) may be movably coupled to the guide bar (621a) of the first drive module (621). The second drive module (622) may move along the guide bar (621a) of the first drive module (621) along a second direction (DR2) and / or the reverse direction of the second direction (DR2) (hereinafter referred to as the second reverse direction). The second drive module (622) may extend along a third direction (DR3).

[0039] A robot arm (100) may be positioned on the side of a second drive module (622). The robot arm (100) may be coupled to a guide bar (622a) positioned on the side of the second drive module (622). For example, the robot arm (100) may be movably coupled to the guide bar (622a) of the second drive module (622). The robot arm (100) may move along the guide bar (622a) of the second drive module (622) in a third direction (DR3) and / or in the reverse direction of the third direction (DR3) (hereinafter referred to as the third reverse direction). The robot arm (100) may move along the first direction (DR1), the first reverse direction, the second direction (DR2), the second reverse direction, the third direction (DR3), and the third reverse direction by means of the aforementioned plurality of rails, the first drive module (621), and the second drive module (622). Accordingly, the robot arm (100) may be positioned on the storage module (200), the radioactive material generation module (300), the radiation dose measurement module (400), and the labeling module (500). The robot arm (100) may unload the vacuum container (222) from the storage module (200). For example, the robot arm (100) may grasp the vacuum container (222) by suction and move the grasped vacuum container (222) to the radioactive material generation module (300), the radiation dose measurement module (400), and the labeling module (500). The robot arm (100) may be extended along a third direction (DR3).

[0040] The storage module (200) can be placed on the upper plate (720). For example, the storage module (200) can be placed between the upper plate (720) and the second driving module (622) in the third direction (DR3), and between a plurality of guide rails (610) in the second direction (DR2).

[0041] The vacuum container (222) can be stored in the storage module (200). For example, the vacuum container (222) can be inserted into and supported within the hole of the storage module (200).

[0042] A radioactive material generating module (300) can be placed on a lower plate (710) through a hole penetrating the upper plate (720). At this time, the radioactive material generating module (300) can be placed spaced apart from the lower plate (710). A portion of the radioactive material generating module (300) can protrude further upward in a third direction (DR3) than the upper surface of the upper plate (720) through the hole in the upper plate (720). The protruding portion of the radioactive material generating module (300) can be placed between the storage module (200) and the label module (500) in a second direction (DR2), and between the upper plate (720) and the second driving module (622) in a third direction (DR3). The radioactive material generating module (300) can provide radioactive material (e.g., a radioactive isotope). For example, the radioactive material generating module (300) is a radioactive isotope 99m It can generate Tc (hereinafter referred to as technetium-99m). The radioactive material generating module (300) is absorbed into alumina beads or other suitable exchange medium. 99 It may include a container or shielded container designed to hold a mother nuclide such as Mo (hereinafter, Molybdenum-99), so-called an adsorption column (e.g., an adsorption column for producing radiopharmaceuticals). When physiological saline is introduced into the adsorption column (20) containing the mother nuclide, the daughter nuclide Technetium-99m is dissolved by the physiological saline and discharged to the outside, whereas Molybdenum-99 adheres strongly to the adsorption column, so that the radioactive isotope Technetium-99m can be extracted from Molybdenum-99. Based on this principle, the radioactive material generating module (300) can generate (or extract) a radioactive isotope, such as Technetium-99m. The radioactive material generated from the radioactive material generating module (300) can be stored in a vacuum container (222).

[0043] The radiation dose measuring module (400) can be placed on the lower plate (710) through a hole penetrating the upper plate (720). At this time, the radiation dose measuring module (400) can be in contact with the lower plate (710). A portion of the radiation dose measuring module (400) can protrude further upward in a third direction (DR3) than the upper surface of the upper plate (720) through the hole in the upper plate (720). The protruding portion of the radiation dose measuring module (400) can be placed between the guide rails (610) in a second direction (DR2), and between the upper plate (720) and the second driving module (622) in a third direction (DR3). The radiation dose measuring module (400) can be placed adjacent to the radioactive material generating module (300) in a first direction (DR1) on the upper plate (720). The radiation dose measuring module (400) can have a hollow cylindrical shape. The radiation dose measuring module (400) can measure the radiation dose of a radioactive material. For example, the radiation dose measuring module (400) can measure the radiation dose of a radioactive isotope (e.g., technetium-99m) generated from the radioactive material generating module (300). In other words, the radiation dose measuring module (400) can measure the radiation dose of a radioactive material contained in a vacuum container (222).

[0044] The label module (500) may be placed on the upper plate (720). The label module (500) may be placed adjacent to the radiation dose measurement module (400) in the second direction (DR2) and between the upper plate (720) and the second driving module (622) in the third direction (DR3). The label module (500) may combine a radioisotope (e.g., technetium-99m) generated from the radioactive material generation module (300) with a radiopharmaceutical. For example, when the radiation dose of the radioisotope (e.g., technetium-99m) generated from the radioactive material generation module (300) satisfies a reference value as a result of measurement from the radiation dose measurement module (400), the radioisotope (e.g., technetium-99m) and the radiopharmaceutical may be combined by the label module (500). For example, the labeling module (500) can label radioactive materials and radiopharmaceuticals.

[0045] FIGS. 6, FIGS. 7, FIGS. 8, and FIGS. 9 are drawings for explaining the movement of the robot arm (100) of FIGS. 1.

[0046] As illustrated in FIG. 6, the robot arm (100) can be positioned on the storage module (200) by means of the operation of the first drive module (621), the second drive module (622), and the robot arm (100). The robot arm (100) can unload the vacuum container (222) from the storage module (200). For example, the robot arm (100) can unload the vacuum container (222) from the storage module (200) by rising in a third direction (DR3) while holding the vacuum container (222) by suction.

[0047] As illustrated in FIG. 7, the robot arm (100) can be positioned on the radioactive material generating module (300) by the operation of the first driving module (621), the second driving module (622), and the robot arm (100). For example, the robot arm (100) can move to the radioactive material generating module (300) while holding the aforementioned vacuum vessel (222), and then deliver the vacuum vessel (222) to the radioactive material generating module (300). When the vacuum vessel (222) is mounted on the radioactive material generating module (300), radioactive material (e.g., technetium-99m) generated from the radioactive material generating module (300) can be injected into the vacuum vessel (222).

[0048] As illustrated in FIG. 8, the robot arm (100) can be positioned on the radiation dose measuring module (400) by means of the operation of the first driving module (621), the second driving module (622), and the robot arm (100). For example, when a radioactive material (e.g., technetium-99m) is filled into a vacuum container (222), the robot arm (100) can move to the radiation dose measuring module (400) while holding the vacuum container (222) filled with the radioactive material. The radiation dose measuring module (400) can measure the radiation dose of the radioactive material (e.g., technetium-99m) inside the vacuum container (222).

[0049] As illustrated in FIG. 9, the robot arm (100) can be positioned on the labeling module (500) by the operation of the first driving module (621), the second driving module (622), and the robot arm (100). For example, when the radiation dose of the radioactive material in the vacuum container (222) satisfies a reference value as a result of measurement from the radiation dose measuring module (400), the robot arm (100) can move the vacuum container (222) containing the radioactive material to the labeling module (500). The labeling module (500) can move the radioactive material in the vacuum container (222) to another container (e.g., a container containing a radioactive pharmaceutical). Accordingly, the radioactive material (e.g., technetium-99m) and the radioactive pharmaceutical can be combined with each other.

[0050] FIG. 10 is a drawing for explaining the method of gripping a vacuum container (222) by the robot arm (100) of FIG. 1.

[0051] As illustrated in FIG. 10, the robot arm (100) may include a hydraulic syringe (111). By means of the suction force generated by the hydraulic syringe (111), the robot arm (100) can grasp the vacuum container (222) of the storage module (200).

[0052] FIG. 11 is a diagram illustrating the process of mixing radioactive material generated from the radioactive material generation module (300) of FIG. 1 with radioactive pharmaceutical.

[0053] As illustrated in FIG. 11, radioactive material (e.g., technetium-99m) in a vacuum container (222) can be transferred to a container containing radioactive pharmaceuticals through a label module (500). For example, when the vacuum container (222) is mounted on the holder (510) of the label module (500), the radioactive material in the vacuum container (222) can be transferred to a container containing radioactive pharmaceuticals through a tube (520).

[0054] Figure 12 is a diagram illustrating the process of mixing radioactive materials and radiopharmaceuticals.

[0055] As illustrated in FIG. 12, a radioactive material (e.g., technetium-99m) and a radiopharmaceutical are mixed in a container (233), and this container (233) can be inserted into a holder (910) of a turntable (900). As the turntable (900) is rotated, the radioactive material (e.g., technetium-99m) and the radiopharmaceutical in the container (233) can be evenly mixed.

[0056] FIG. 13 is a flowchart illustrating a method for extracting radioactive pharmaceuticals according to one embodiment.

[0057] First, a robot arm (100) grasps a vacuum container (222), and the robot arm (100) that has grasped the vacuum container (222) can move to a radioactive material generation module (300) (S100).

[0058] Afterwards, the radioactive material generation module (300) can extract (or generate) radioactive material and inject the extracted radioactive material into a vacuum vessel (222) (S200).

[0059] Next, the robot arm (100) can move the vacuum container (222) containing the radioactive material to the radiation dose measurement module (400). Then, the radiation dose of the radioactive material injected into the vacuum container (222) can be measured by the radiation dose measurement module (400) (S300). When the measured radiation dose of the radioactive material is greater than or equal to a preset reference value, the robot arm (100) can move the vacuum container (222) containing the radioactive material to the labeling module (500).

[0060] Afterwards, the label module (500) can combine radioactive material and radiopharmaceutical (S400).

[0061] Next, radioactive material and radiopharmaceutical can be mixed using a rotating plate (900) (S500).

[0062] Meanwhile, when the measured radiation dose of the radioactive material is less than a preset threshold, the robot arm (100) moves the vacuum container (222) containing the radioactive material to the radioactive material generation module (300). Subsequently, the radioactive material generation module (300) can additionally extract radioactive material and inject it into the vacuum container (222). For example, additional radioactive material can be generated until the radiation dose of the extracted radioactive material is greater than or equal to the threshold.

[0063] According to one embodiment, the synthesis process of a radiopharmaceutical for labeling by mechanism of accumulation on a radioisotope (e.g., technetium-99m) is automated, so the productivity and versatility of the radiopharmaceutical are excellent.

[0064] In addition, according to one embodiment, quantitative production is possible during the production of radioactive isotopes and the synthesis of labeled pharmaceuticals.

[0065] In addition, according to one embodiment, a safe working environment can be provided because the worker is not exposed to a hazardous environment. For example, the problem of radiation exposure can be overcome by utilizing a robot-based automatic control system in a radioactive environment, such as the production environment of radiopharmaceuticals. Therefore, the radiation dose can be drastically reduced during the process of producing radioisotopes.

[0066] According to one embodiment, the production of radioisotopes, measurement of radiation dose, and the pre-processing of labeling and syringe formulation of radiopharmaceuticals can be carried out in an all-in-one manner.

[0067] As described above, the disclosed embodiments have been explained with reference to the attached drawings. Those skilled in the art will understand that the present disclosure may be practiced in forms different from the disclosed embodiments without changing the technical spirit or essential features of the present disclosure. The disclosed embodiments are illustrative and should not be interpreted restrictively. Explanation of the symbols

[0068] 1000: Radiopharmaceutical extraction system using an automated control robot 710: Lower plate 720: Upper plate 800: Support column 100: Robotic Arm 610: Guide rail 621: 1st drive module 622: Second drive module 621a, 622a: Guide bar 200: Storage Module 222: Vacuum container 300: Radioactive Material Generation Module; 400: Radiation dose measurement module 500: Cover Module DR1: First direction DR2: Second Direction DR3: Third Direction

Claims

Claim 1 An upper plate; a lower plate; a plurality of guide rails on the upper plate; a first drive module movably coupled to the plurality of guide rails in a first direction; a second drive module movably coupled to the first drive module in a second direction; a robot arm movably coupled to the second drive module in a third direction; a storage module disposed on the upper plate and housing a vacuum container; a radiation dose measuring module disposed on the upper plate and measuring the radiation dose of a radioactive isotope; a labeling module disposed on the upper plate and positioned adjacent to the radiation dose measuring module in a second direction, and positioned between the upper plate and the second drive module in a third direction, and combining the radioactive isotope and the radiopharmaceutical; A radioactive drug extraction system utilizing an automatic control robot, comprising a radioactive material generating module disposed on the lower plate through a hole penetrating the upper plate, spaced apart from the lower plate, and having a portion of which protrudes further upward in a third direction than the upper surface of the upper plate; wherein the robot arm moves to the radioactive material generating module while gripping the vacuum container and delivers the vacuum container to the radioactive material generating module, and when the radiation dose of the radioactive material inside the vacuum container measured by the radiation dose measuring module is greater than or equal to a preset reference value, the vacuum container is moved to the labeling module. Claim 2 delete Claim 3 A radiopharmaceutical extraction system utilizing an automatic control robot according to claim 1, further comprising a plurality of support pillars disposed between the lower plate and the upper plate. Claim 4 A radioactive drug extraction system utilizing an automatic control robot, wherein the first driving module includes a guide bar to which the second driving module is movably coupled. Claim 5 A radiopharmaceutical extraction system utilizing an automatic control robot, wherein the second driving module comprises a guide bar to which the robot arm is movably coupled. Claim 6 A radiopharmaceutical extraction system utilizing an automatic control robot according to claim 1, wherein the plurality of guide rails are arranged on the upper plate facing each other in the second direction. Claim 7 In claim 6, the storage module, the radioactive material generation module, the radiation dose measurement module, and the labeling module are arranged between the plurality of guide rails, in a radioactive pharmaceutical extraction system utilizing an automatic control robot. Claim 8 A radiopharmaceutical extraction system utilizing an automatic control robot, wherein the robot arm grasps the vacuum vessel by an adsorption method in claim 1. Claim 9 A radiopharmaceutical extraction system utilizing an automatic control robot according to claim 1, wherein when the radiation dose of the radioisotope measured by the radiation dose measurement module is greater than or equal to a preset reference value, the radioisotope and the radiopharmaceutical are combined by the labeling module. Claim 10 An upper plate; a lower plate; a plurality of guide rails on the upper plate; a first drive module movably coupled to the plurality of guide rails in a first direction; a second drive module movably coupled to the first drive module in a second direction; a robot arm movably coupled to the second drive module in a third direction; a storage module disposed on the upper plate and housing a vacuum container; a radiation dose measuring module disposed on the upper plate and measuring the radiation dose of a radioactive isotope; a labeling module disposed on the upper plate, disposed adjacent to the radiation dose measuring module in a second direction, disposed between the upper plate and the second drive module in a third direction, and combining the radioactive isotope and the radiopharmaceutical. A method for extracting a radioactive drug using an automatic control robot utilizing a system comprising a radioactive material generating module disposed on the lower plate through a hole penetrating the upper plate, spaced apart from the lower plate, and having a portion of which protrudes further upward in a third direction than the upper surface of the upper plate, the method comprising: a step in which the robot arm grasps a vacuum container of the storage module; a step in which the robot arm, while grasping the vacuum container, moves to the radioactive material generating module and delivers the vacuum container to the radioactive material generating module; a step in which the radioactive material generating module extracts radioactive material and injects the extracted radioactive material into the vacuum container; a step in which the robot arm moves the vacuum container into which the radioactive material has been injected to the radiation dose measuring module; a step in which the radiation dose measuring module measures the radiation dose of the radioactive material inside the vacuum container; and a step in which, when the measured radiation dose of the radioactive material is greater than or equal to a preset reference value, the robot arm moves the vacuum container to the labeling module.A method for extracting a radiopharmaceutical using an automatic control robot, characterized in that the labeling module includes the step of combining the radioactive material and the radiopharmaceutical, and when the radiation dose of the measured radioactive material is less than the reference value, the robot arm moves the vacuum vessel back to the radioactive material generation module, and the radioactive material generation module additionally generates radioactive material until the radiation dose of the radioactive material is greater than or equal to the reference value.

Images