Cutting guide wire and thrombus aspiration system

Abstract

In the cutting guide wire and thrombus suction system provided in the present application, the cutting guide wire comprises a guide wire body and a thrombus cutting member, the end portion of the guide wire body is suitable for being installed through the suction catheter, the thrombus cutting member is connected to the end portion of the guide wire body, the thrombus cutting member is suitable for being placed within the suction catheter, and the thrombus cutting member has a cutting state that cuts a thrombus within the suction catheter while moving within the suction catheter under the driving of the guide wire body, wherein the thrombus cutting member includes a cutting portion, and the cross-sectional area of ​​the cutting portion gradually increases along the direction from the end portion to the apex. A thrombus cutting member is connected to the lower end of the guide wire body, and the thrombus cutting member includes a cutting section. As the cross-sectional area of ​​the cutting section gradually increases along the direction from the lower end to the apex, when cutting a thrombus in the suction catheter by placing and moving the thrombus cutting member through the guide wire body, the cutting section forming a tip shape can cut and fragment the clogged thrombus in the suction catheter, and prevent the inside of the suction catheter from becoming clogged.

Description

Technology Field

[0001] The present application relates to the field of medical device technology, specifically to a cutting guide wire and a thrombus suction system.

[0002] <Cross-reference to related applications>

[0003] This application was filed with the Chinese Intellectual Property Office on November 17, 2022, and claims priority to a Chinese patent application with application number 202211439559.5 and title of invention “Cutting guide wire and thrombus suction system”, and incorporates all of its contents by reference into this application. Background Technology

[0004] Thrombus aspiration is an effective method recently used clinically that rapidly extracts the thrombus occluding the lesioned blood vessel through mechanical action, thereby reducing the thrombotic burden and microvascular embolism, altering coronary blood flow, and aiming to reduce the probability of "slow flow" or "no-reflow" occurring after surgery.

[0005] In the prior art, a thrombus suction catheter system comprises a negative pressure suction pump, a thrombus suction catheter, an inner tube, a Y-type connector, and a guide wire. When in use, the guide wire is first sent to the lesion site in the human body, the thrombus suction catheter and the inner tube are inserted into the lesion site along the tail end of a super smooth guide wire, the negative pressure suction pump and the thrombus suction catheter are connected through the Y-type connector, the guide wire and the inner tube are withdrawn, and then negative pressure is applied to the thrombus suction catheter through a negative pressure suction device, thereby aiming the catheter end at the thrombus and realizing the effect of extracting the thrombus from the blood vessel to the outside of the body through the thrombus suction catheter.

[0006] However, while the above-described thrombus suction catheter system can suction newly formed, flexible emboluses and acute thrombus masses, in the case of subacute thrombi, the tube is prone to blockage during suction, which may affect thrombus extraction by the thrombus suction catheter. Prior art literature

[65535] 1. Japanese Utility Model Publication No. Hei 02-071509 (19900531) 2. Japanese Patent Publication No. JP 2019-022755 (20190214) The problem to be solved

[0007] Accordingly, the present application aims to solve the technical problem of the prior art, which can aspirate newly formed, flexible embolus and acute thrombus mass, but in the case of subacute thrombus, the tube is prone to blockage during aspiration, which can affect thrombus extraction by the thrombus aspiration catheter. means of solving the problem

[0008] Accordingly, the present application provides a cutting guide wire, and

[0009] A guide wire body suitable for penetrating and installing the fabric inside a suction catheter;

[0010] A thrombus cutting member that is connected to the fabric of the guide wire body, is suitable for placement within the suction catheter, and has a cutting state that cuts a thrombus within the suction catheter while moving within the suction catheter under the driving of the guide wire body;

[0011] Here, the thrombus cutting member includes a cutting portion, and the cross-sectional area of ​​the cutting portion gradually increases along the direction from the distal end to the apical end.

[0012] Optionally, the side wall surface of the cutting portion is a truncated cone or a parabolic surface.

[0013] Optionally, a plurality of protrusions and / or a plurality of depressions are provided on the peripheral surface of the cutting portion.

[0014] Optionally, the thrombus cutting member further includes a connecting portion, and the connecting portion is connected between the guide wire body and the cutting portion.

[0015] Optionally, the cross-sectional area of ​​the above connection is gradually increased along the direction from the root end to the root end.

[0016] Optionally, the connection is a truncated cone structure or a parabolic structure.

[0017] Optionally, the thrombus cutting member further includes a spiral portion, the spiral portion is connected to the connecting portion, and the guide wire body is installed through the spiral portion.

[0018] Optionally, a knob unit is further included and connected to the near end of the guide wire body to drive the guide wire body to rotate.

[0019] A thrombus suction system includes the cutting guide wire described above.

[0020] Optionally, the device further comprises a negative pressure member, a connector, a cutting guide wire, a suction catheter, and a catheter handle, wherein the connector is connected between the negative pressure member and the suction catheter, the catheter handle is connected to the proximal end of the suction catheter, the cutting guide wire is suitable for placement within the suction catheter, and a plurality of side holes are provided in the fabric sidewall of the suction catheter. Effects of the invention

[0021] The cutting guide wire and thrombus suction system provided in this application have the following advantages.

[0022] 1. The cutting guide wire provided in the present application comprises a guide wire body and a thrombus cutting member, wherein the end portion of the guide wire body is suitable for being installed through a suction catheter, and the thrombus cutting member is connected to the end portion of the guide wire body, and the thrombus cutting member is suitable for being placed within the suction catheter, and the thrombus cutting member has a cutting state that cuts a thrombus within the suction catheter while moving within the suction catheter under the driving of the guide wire body; wherein the thrombus cutting member includes a cutting portion, and the cross-sectional area of ​​the cutting portion gradually increases along the direction from the end portion to the apex.

[0023] 2. In the cutting guide wire provided in the present application, the thrombus cutting member further comprises a spiral portion, the spiral portion is connected to the connecting portion, and the guide wire body is installed through the spiral portion.

[0024] In a cutting guide wire of this structure, by providing a spiral portion at the connection, when removing a blood clot, the entire spiral portion is inserted into the blood clot to cut and crush the blood clot, and then when extracting and separating the spiral portion from the blood clot, the spiral portion pulls out the crushed blood clot from the blood clot mass, thereby improving the blood clot removal effect.

[0025] 3. The thrombus suction system provided in the present application further comprises a negative pressure member, a connector, a cutting guide wire, a suction catheter, and a catheter handle, wherein the connector is connected between the negative pressure member and the suction catheter, the catheter handle is connected to the proximal end of the suction catheter, the cutting guide wire is suitable for placement within the suction catheter, and a plurality of side holes are provided in the outer side wall of the suction catheter.

[0026] In a thrombus suction system of this structure, by providing multiple side holes in the front side wall of the suction catheter, it is possible to remove thrombi from the inner wall of the blood vessel using a thrombus suction catheter that is much smaller than the inner diameter of the blood vessel. Furthermore, even if either the head end opening or the side hole of the suction catheter is blocked by a thrombus, the other opening can continue to suction the thrombus, allowing for rapid and comprehensive suction of the thrombus without the need to replace the catheter, thereby reducing the amount of bleeding. Brief explanation of the drawing

[0027] In order to more clearly explain the specific embodiments of the present application or the technical methods of the prior art, the attached drawings necessary for explaining the specific embodiments or prior art will be briefly described below. The attached drawings described below are merely some embodiments of the present application, and it is obvious to those skilled in the art that other attached drawings can be obtained based on these attached drawings without requiring creative labor. FIG. 1 is a schematic diagram of the overall structure of the cutting guide wire and thrombus suction system provided in an embodiment of the present application. FIG. 2 is a schematic diagram of the structure of a catheter handle among the cutting guide wire and thrombus suction system provided in an embodiment of the present application. FIG. 3 is a schematic diagram of the disassembled structure of a catheter handle among the cutting guide wire and thrombus suction system provided in an embodiment of the present application. FIG. 4 is a schematic diagram of the structure of the cutting guide wire and thrombus suction system provided in an embodiment of the present application. FIG. 5 is a schematic diagram showing the exploded structure of the cutting guide wire and thrombus suction system provided in an embodiment of the present application. FIG. 6 is a schematic diagram of the structure of a thrombus cutting member among the cutting guide wire and thrombus suction system provided in an embodiment of the present application. FIG. 7 is a schematic diagram of another structure of a thrombus cutting member among the cutting guide wire and thrombus suction system provided in an embodiment of the present application. Specific details for implementing the invention

[0028] The technical solution of the present application will be explained clearly and completely in conjunction with the attached drawings below. It is obvious that the described embodiments are merely some embodiments of the present application and not all embodiments. All other embodiments that can be obtained by a person skilled in the art without requiring creative labor based on the embodiments of the present application fall within the scope of protection of the present invention.

[0029] In the description of this application, the orientations or positional relationships indicated by terms such as "center," "top," "bottom," "left," "right," "vertical," "horizontal," "inside," "outside," etc., are those illustrated in the attached drawings and are merely intended to facilitate the description and simplified explanation of this application; they do not indicate or imply that the device or element indicated must possess a specific orientation, be configured in a specific orientation, or be operated in a specific orientation, and therefore should not be understood as a limitation to this application. Furthermore, the terms "first," "second," and "third" are used solely for illustrative purposes and should not be understood as indicating or implying relative importance. Additionally, the technical features mentioned in the various embodiments of this application described below may be combined with one another insofar as they do not contradict each other.

[0030] In the description of the present application, it is to be explained that the original part described in the present application is one end approaching the thrombus cutting member, and the proximal end is one end approaching the catheter handle.

[0031] Example 1

[0032] The present embodiment provides a cutting guide wire, comprising a guide wire body (1) and a thrombus cutting member (2) as shown in FIGS. 1 to 7, wherein the thrombus cutting member (2) is connected to the end of the guide wire body (1), and the end of the guide wire body (1) and the thrombus cutting member (2) are used to be installed through the suction catheter (3), and the thrombus cutting member (2) is driven to reciprocate within the suction catheter (3) by holding the end of the guide wire body (1) with one's hand, thereby cutting the thrombus within the suction catheter (3), so as to prevent the suction catheter (3) from becoming blocked and affecting the extraction of the thrombus from the thrombus suction catheter (3).

[0033] As illustrated in FIGS. 6 and 7, the thrombus cutting member (2) includes a cutting portion (21) and a connecting portion (22), and the connecting portion (22) is connected between the guide wire body (1) and the cutting portion (21). Here, along the direction from the root end to the root end, the cross-sectional area of ​​the cutting portion (21) gradually increases, that is to say, the shape of the cutting portion (21) is a truncated cone structure, a conical structure, or a parabolic structure.

[0034] In some other embodiments, the cutting portion (21) may have a different structure having a tip shape, and it can be understood that the tip-forming structure here allows the cutting portion (21) to be more easily inserted into the blood clot when it comes into contact with the blood clot, thereby cutting and crushing the blood clot.

[0035] In some other embodiments, it can be understood that a plurality of protrusions are provided on the surface of the cutting portion (21), and the protrusions can improve the cutting effect against blood clots, and a plurality of depressions may also be provided.

[0036] As shown in FIG. 6, the connecting part (22) is columnar, and the columnar structure allows the thrombus cutting member (2) to move easily within the thrombus.

[0037] In some other embodiments, the cross-sectional area of ​​the connecting portion (22) gradually increases along the direction from the root end to the root end, that is, the connecting portion (22) is a truncated cone structure or a parabolic structure.

[0038] In some other embodiments, the thrombus cutting member (2) further includes a spiral portion (23), the spiral portion (23) is fixedly connected to a connecting portion (22), and a guide wire body (1) is installed through the spiral portion (23). When removing a thrombus, the spiral portion (23) is inserted into the thrombus to cut and crush the thrombus, and then when extracting and separating the spiral portion (23) from the thrombus, the spiral portion (23) pulls out the crushed thrombus from the thrombus mass, thereby improving the effect of removing the thrombus.

[0039] In some other embodiments, a knob unit is connected to the end of the guide wire body (1), so that an operator can control the guide wire body (1) to rotate through the knob unit.

[0040] Here, the guide wire body (1) uses a nitinol material, has excellent shape memory, and includes a hydrophilic coating on the surface of the guide wire body (1), so that the operability of the guide wire body (1) is even better.

[0041] In some other embodiments, the connection position between the guide wire body (1) and the thrombus cutting member (2) can form a narrow angle, that is, a narrow angle exists between the axis of the guide wire body (1) and the axis of the thrombus cutting member (2), so that the curved thrombus cutting member (2) can crush the thrombus and at the same time detach the thrombus from the blood vessel wall, which is more advantageous for thrombus absorption.

[0042] Example 2

[0043] The present embodiment provides a thrombus suction system and, as shown in FIGS. 1 to 7, includes a suction catheter (3), a catheter handle (4), a bushing (5), a protective sleeve (6), and a cutting guide wire, wherein the cutting guide wire is the cutting guide wire of Example 1.

[0044] As shown in FIGS. 2 and 3, the catheter handle (4) is inserted and connected to the protective sleeve (6), the protective sleeve (6) is inserted and connected to the suction catheter (3) through the bushing (5), the cutting guide wire material is inserted and installed inside the suction catheter (3), and the catheter handle (4) is used to control the catheter.

[0045] Here, as shown in FIGS. 4 and 5, a plurality of side holes (31) are provided in the base of the suction catheter (3), and by providing side holes (31) in the side wall of the base of the suction catheter (3), it is possible to remove blood clots from the inner wall of the blood vessel using a blood clot suction catheter (3) that is much smaller than the inner diameter of the blood vessel. In addition, even if either the head end opening or the side hole (31) of the suction catheter (3) is blocked by a blood clot, the other opening can continue to suction the blood clot, so that blood clots can be sucked quickly and completely without the need to replace the catheter, and the amount of bleeding can be reduced.

[0046] The number of side holes (31) can be determined according to the size or usage needs of the suction catheter (3), for example, 2, 3, 5, 8, etc., and preferably the side holes (31) are provided on the upper side of the suction catheter (3) to enable a wider range of thrombus suction.

[0047] Here, the suction catheter (3) uses a three-layer composite coating technology, the inner layer is a PTFE layer with low resistance, which is advantageous for the passage of blood clots, the middle layer is a stainless steel knit structure with strong support, excellent push performance, and strong resistance to bending, the outer layer is a Pebax resin with excellent biocompatibility, and development marker points are provided at both ends of the side hole (31) to indicate the position of the side hole (31), and a development segment is provided at the head end of the suction catheter (3) to indicate the position of the head end.

[0048] In some other embodiments, the thrombus suction system further comprises a negative pressure member and a connector, the connector being connected between the negative pressure member and a suction catheter (3), wherein the negative pressure member is a negative pressure suction pump and the connector is a rotary or button-type Y valve, which can effectively prevent blood oozing.

[0049] The operation flow of the thrombus suction system provided in this embodiment is as follows.

[0050] First, a cutting guide wire is inserted into the lesion site of the human body along the relevant device, and a suction catheter (3) is inserted into the lesion site along the tail end of the cutting guide wire. A negative pressure suction pump is connected to the side branch of the Y-type connector and tightened by turning. After withdrawing the cutting guide wire, negative pressure is applied through the negative pressure suction pump to stabilize the pressure. Once the pressure is stabilized, the catheter is rotated while slowly pushing to aim the catheter side hole (31) at the blood clot, and the blood clot is drawn out from inside the blood vessel to outside the body. If the tube is blocked, the blood clot is cut using the assembled cutting guide wire, and the blood clot is absorbed while being cut.

[0051] Of course, the embodiments described above are merely examples for clear explanation and are not intended to limit the embodiments. Those skilled in the art may further implement various forms of changes and variations based on the descriptions above. It is not possible to list all embodiments infinitely, nor is it necessary to do so. Obvious changes or variations derived thereby are still within the scope of the claims of this application. Explanation of the symbols

[0052] 1: Guide wire body 2: Thrombus cutting part 21: Cutting part 22: Connection part 23: Spiral part 3: Suction catheter 31: Sidehole 4: Catheter handle 5: Bushing 6: Protective Sleeve

Claims

Claim 1 A cutting guide wire comprising: a guide wire body (1) suitable for the material to be installed through the suction catheter (3); a thrombus cutting member (2) connected to the material of the guide wire body (1), suitable for being placed within the suction catheter (3), and having a cutting state that cuts a thrombus within the suction catheter (3) while moving within the suction catheter (3) under the driving of the guide wire body (1); wherein the thrombus cutting member (2) includes a cutting portion (21), and the cross-sectional area of ​​the cutting portion (21) gradually increases along the direction from the material to the root end, and the thrombus cutting member (2) further includes a connecting portion (22), the connecting portion (22) is connected between the guide wire body (1) and the cutting portion (21), and the cross-sectional area of ​​the connecting portion (22) gradually increases along the direction from the root end to the material, and the connecting portion (22) is a truncated cone structure or a parabolic structure. Claim 2 A cutting guide wire according to claim 1, characterized in that the side wall surface of the cutting part (21) is a frustum of a cone or a parabolic surface. Claim 3 A cutting guide wire according to claim 1, characterized in that a plurality of protrusions and / or a plurality of depressions are provided on the peripheral surface of the cutting portion (21). Claim 4 delete Claim 5 delete Claim 6 delete Claim 7 A cutting guide wire according to claim 1, wherein the thrombus cutting member (2) further comprises a spiral portion (23), the spiral portion (23) is connected to the connecting portion (22), and the guide wire body (1) is installed through the spiral portion (23). Claim 8 A cutting guide wire according to claim 7, further comprising a knob unit connected to the end of the guide wire body (1) and driven to rotate the guide wire body (1). Claim 9 A thrombus suction system characterized by including a cutting guide wire according to any one of claims 1 to 3, 7, and 8. Claim 10 A thrombus suction system according to claim 9, further comprising a negative pressure member, a connector, a cutting guide wire, a suction catheter (3), and a catheter handle (4), wherein the connector is connected between the negative pressure member and the suction catheter (3), the catheter handle (4) is connected to the proximal end of the suction catheter (3), the cutting guide wire is suitable for placement within the suction catheter (3), and a plurality of side holes (31) are provided in the outer side wall of the suction catheter (3).

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