Antiviral industrial deodorant composition comprising pomegranate extract and turmeric extract and method for producing the same

Abstract

The present invention relates to an antiviral industrial deodorizer composition comprising pomegranate extract and turmeric extract and a method for manufacturing the same. More specifically, the invention relates to an antiviral industrial deodorizer composition and a method for manufacturing the same that not only maintains excellent deodorizing effects and persistence when applied to industrial sites, but also has excellent dispersibility, prevents secondary environmental pollution, and has excellent antiviral activity.

Description

Technology Field

[0001] The present invention relates to an antiviral industrial deodorizer composition comprising pomegranate extract and turmeric extract and a method for manufacturing the same. More specifically, the invention relates to an eco-friendly antiviral industrial deodorizer composition based on natural ingredients that exhibits excellent deodorizing effects against various malodorous substances generated in industrial sites and simultaneously possesses antiviral activity, and a method for manufacturing the same. Background Technology

[0002] With the recent rapid progress of industrialization, environmental pollution and civil complaints caused by odorous substances generated in various industrial sectors, such as the livestock industry, food processing industry, chemical industry, and waste treatment industry, are emerging as serious social issues. In particular, odorous substances such as ammonia (NH3), trimethylamine (N(CH3)3), methyl mercaptan (CH3SH), and hydrogen sulfide (H2S) cause strong discomfort even in minute quantities, and continuous exposure leads to headaches, vomiting, and respiratory diseases, posing a serious threat to the health of workers and the living environment of residents in surrounding areas.

[0003] Deodorization technologies currently used in industrial settings can be broadly classified into physical, chemical, and biological methods. Physical methods include activated carbon adsorption, zeolite adsorption, and membrane separation; however, these are difficult to apply to large-scale industrial facilities due to high adsorbent replacement costs and limited treatment capacity. Biological methods, such as biofilters and bioscrubbers, offer low operating costs but have the disadvantage of requiring strict management of operating conditions to maintain microbial activity, while their treatment efficiency is heavily dependent on environmental conditions.

[0004] The most widely used chemical deodorization method involves decomposing or deodorizing odorous substances through mechanisms such as acid-base neutralization, oxidation, and chlorination reactions using aqueous ammonia solutions (15-25%), sodium hydroxide, sodium hypochlorite, hydrogen peroxide, and ozone. While these chemical deodorizers provide rapid initial treatment effects and high removal rates, they have fundamental limitations, such as secondary environmental pollution caused by residual chemicals after the reaction, worker safety issues due to corrosiveness and toxicity, and the need for frequent reprocessing due to a lack of sustained effect.

[0005] Moreover, with the recent outbreaks of infectious diseases such as COVID-19, MERS, and SARS, social interest and demands for regulations regarding the prevention of the spread of viruses and pathogenic microorganisms within industrial facilities have increased significantly. However, existing chemical deodorizers focus only on simple odor removal, resulting in very limited antiviral effects against influenza viruses, coronaviruses, and noroviruses. Furthermore, there are concerns regarding the inconvenience of having to use additional disinfectants and the side effects caused by the excessive use of chemicals.

[0006] Meanwhile, as social demand for environmentally friendly and sustainable industrial development increases, interest in developing eco-friendly deodorizers based on natural ingredients is growing. Although research results have reported that bioactive substances such as polyphenol compounds, flavonoids, and terpenes contained in natural plant extracts, such as pomegranates, turmeric, green tea, and citrus fruits, exhibit antioxidant, antibacterial, and antiviral activities, technical challenges such as composition optimization, ensuring stability, and enhancing the duration of effectiveness to commercialize these natural ingredients as industrial deodorizers remain unresolved.

[0007] In particular, natural extracts exhibit relatively lower deodorizing efficiency compared to chemical deodorizers when used alone, and their commercial application has been limited due to issues such as insufficient stability in aqueous solutions, rapid decomposition of active ingredients, and difficulties in standardizing raw materials. Furthermore, there is a lack of research on methods to maximize synergistic effects through the elucidation of interaction mechanisms among various natural ingredients, the derivation of optimal blending ratios, and the development of pretreatment technologies utilizing herbal ingredients.

[0008] Therefore, there is an urgent need to develop an innovative industrial deodorizer composition that can simultaneously achieve excellent deodorizing effects and antiviral activity based on natural ingredients, while ensuring persistence and stability comparable to chemical deodorizers. Prior art literature

[0009] Republic of Korea Published Patent No. 10-2024-0040367 (March 28, 2024) The problem to be solved

[0010] The present invention has been devised in consideration of the above points, and aims to provide an eco-friendly and safe industrial deodorizer composition based on natural ingredients that exhibits excellent deodorizing effects against various malodorous substances generated in industrial sites, has excellent persistence of deodorizing effects, and simultaneously possesses antiviral activity, as well as a method for manufacturing the same. means of solving the problem

[0011] To solve the above-mentioned problem, the industrial deodorizer composition of the present invention comprises 3 to 10 weight% of pomegranate extract, 5 to 8 weight% of turmeric extract, 0.5 to 15 weight% of water-soluble polymer, 0.1 to 5 weight% of emulsifier, and 60 to 90 weight% of excipient.

[0012] In a preferred embodiment of the present invention, the pomegranate extract and turmeric extract may be pretreated with one or more herbal extracts selected from the group consisting of lavender extract and rosemary extract.

[0013] In a preferred embodiment of the present invention, the weight ratio of the pomegranate extract to the turmeric extract may be 1:1.0 to 1:2.6.

[0014] In a preferred embodiment of the present invention, the pomegranate extract is extracted from pomegranate fruit or pomegranate peel and contains ellagic acid and anthocyanin as active ingredients, and the turmeric extract is extracted from rhizome and may contain curcumin and turmerone as active ingredients.

[0015] In a preferred embodiment of the present invention, the composition may exhibit a deodorizing effect against one or more substances selected from the group consisting of ammonia, trimethylamine, methyl mercaptan, and hydrogen sulfide.

[0016] In a preferred embodiment of the present invention, the water-soluble polymer may be one or more selected from the group consisting of polyvinyl alcohol (PVA), gelatin, carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC), sodium alginate, pectin, chitosan, carrageenan, and xanthan gum.

[0017] In a preferred embodiment of the present invention, the emulsifier may be one or more selected from the group consisting of sodium stearate, sodium oleate, sodium laurate, sorbitan monooleate, sorbitan monostearate, polyethylene glycol monostearate, glycerin monostearate, Tween 20, Tween 60, Tween 80, poloxamer, and lecithin.

[0018] In a preferred embodiment of the present invention, the excipient may include one or more selected from the group consisting of distilled water, ethanol, palm oil, glycerin, propylene glycol, butylene glycol, sorbitol, mannitol, citric acid, sodium citrate, sodium dihydrogen phosphate, disodium hydrogen phosphate, sodium chloride, sodium sulfate, and sodium benzoate.

[0019] In a preferred embodiment of the present invention, the composition has antiviral activity, and the antiviral may have antiviral activity against one or more viruses selected from the group consisting of influenza virus, coronavirus (SARS-CoV-2), norovirus, rotavirus, adenovirus, rhinovirus, enterovirus, RSV (Respiratory Syncytial Virus), and parainfluenza virus.

[0020] Meanwhile, the method for preparing an industrial deodorizer composition of the present invention comprises the following steps: (a) preparing a pomegranate extract by hot water extraction or ethanol extraction from a pomegranate; (b) preparing a turmeric extract by hot water extraction or ethanol extraction from a turmeric; (c) preparing a primary mixture by mixing 3 to 10 weight% of the pomegranate extract and 5 to 8 weight% of the turmeric extract with 0.5 to 15 weight% of a water-soluble polymer; (d) adding 0.1 to 5 weight% of an emulsifier to the primary mixture and stirring and mixing; (e) adding and mixing 60 to 90 weight% of an excipient; and (f) preparing a deodorizer composition by homogenization treatment.

[0021] In a preferred embodiment of the present invention, in steps (a) and (b), the pomegranate extract and turmeric extract may be pretreated with one or more herbal extracts selected from the group consisting of lavender extract and rosemary extract.

[0022] In a preferred embodiment of the present invention, the herb extract pretreatment may be performed by immersing pomegranate extract and turmeric extract, respectively, in an aqueous solution of herb extract at a concentration of 0.05 to 0.2% and aging them at a low temperature of 2°C to 8°C for 4 to 12 hours, and then centrifuging (2,000 rpm to 5,000 rpm, 5 to 20 minutes) to recover the supernatant.

[0023] In a preferred embodiment of the present invention, in step (a), the pomegranate extract is prepared by extracting from pomegranate fruit using 60% to 80% ethanol for 12 to 48 hours and then concentrating, and in step (b), the turmeric extract is prepared by extracting from turmeric rhizomes with hot water at 50°C to 70°C and then freeze-drying. Effects of the invention

[0024] The industrial deodorizing composition of the present invention, comprising pomegranate extract and turmeric extract, exhibits an excellent deodorizing effect of over 90% against various malodorous substances such as ammonia, trimethylamine, methyl mercaptan, and hydrogen sulfide due to the synergistic effect of ellagic acid and anthocyanin in the pomegranate extract and curcumin and turmerone in the turmeric extract. Furthermore, the deodorizing effect is further enhanced through pretreatment using lavender and rosemary herb extracts, and excellent deodorizing performance can be achieved particularly with complex herb pretreatment. Fourth, it exhibits excellent antiviral activity against influenza viruses, etc., thereby contributing to the prevention of virus spread within industrial facilities. Additionally, composed of natural ingredients, it is safe for the human body and environmentally friendly, does not cause secondary environmental pollution, and has the advantage of being easy to apply to various industrial sites by securing excellent dispersibility and stability through the appropriate combination of water-soluble polymers and emulsifiers. Specific details for implementing the invention

[0025] Hereinafter, embodiments of the present invention are described in detail with reference to the attached drawings so that those skilled in the art can easily implement the present invention. The present invention may be embodied in various different forms and is not limited to the embodiments described herein. In the drawings, parts unrelated to the explanation have been omitted to clearly explain the present invention, and the same reference numerals are assigned to identical or similar components throughout the specification.

[0027] The industrial deodorant composition of the present invention comprises pomegranate extract, turmeric extract, a water-soluble polymer, an emulsifier, and an excipient.

[0028] At this time, the pomegranate extract is extracted from pomegranate fruit or pomegranate peel and may contain one or more polyphenol compounds selected from ellagic acid, anthocyanin, gallotannin, punicalagin, anthocyanidin, quercetin, luteolin, and catechin as active ingredients, and preferably may contain ellagic acid and anthocyanin.

[0029] Turmeric extract is extracted from turmeric rhizomes and may contain one or more curcuminoids or essential oil components selected from curcumin, turmerone, demethoxycurcumin, bisdemethoxycurcumin, ar-turmerone, curlone, curcumene, zingiberene, and β-sesquiphellandrene as active ingredients, and preferably may contain curcumin and turmerone.

[0030] In addition, the above pomegranate extract and turmeric extract may be pretreated with one or more herbal extracts selected from the group consisting of lavender extract and rosemary extract.

[0031] Specifically, the lavender extract may contain one or more terpene compounds selected from linalool, linalyl acetate, lavanduol, lavanduyl acetate, borneol, camphor, 1,8-cineole, and tannin, and preferably may contain linalool and linalyl acetate.

[0032] Rosemary extract may contain one or more diterpene or phenolic compounds selected from rosmarinic acid, carnosol, carnosic acid, ursolic acid, betulinic acid, oleanolic acid, 1,8-cineole, camphor, α-pinene, and borneol, and preferably may contain rosmarinic acid and carnosol.

[0033] The water-soluble polymer may include one or more selected from polyvinyl alcohol (PVA), gelatin, carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC), methylcellulose (MC), hydroxypropylmethylcellulose (HPMC), sodium alginate, calcium alginate, pectin, chitosan, chitin, carrageenan, agarose, xanthan gum, guar gum, locust bean gum, and acacia gum, preferably one or more selected from polyvinyl alcohol (PVA), carboxymethylcellulose (CMC), and chitosan, and more preferably polyvinyl alcohol (PVA).

[0034] The emulsifier may include one or more selected from sodium stearate, sodium oleate, sodium palmitate, sodium laurate, sodium myristate, sorbitan monooleate, sorbitan monostearate, sorbitan monolaurate, polyethylene glycol monostearate, polyethylene glycol monooleate, glycerin monostearate, glycerin monooleate, Tween 20, Tween 40, Tween 60, Tween 80, Span 20, Span 40, Span 60, Span 80, poloxamer, lecithin, cetyl alcohol, and cetearyl alcohol, preferably one or more selected from Tween 20, Tween 60, Tween 80, and poloxamer, and more preferably Tween 80.

[0035] The excipient may include one or more selected from distilled water, ethanol, methanol, isopropanol, butanol, palm oil, soybean oil, olive oil, sunflower oil, glycerin, propylene glycol, butylene glycol, dipropylene glycol, sorbitol, mannitol, xylitol, erythritol, maltitol, citric acid, sodium citrate, potassium citrate, sodium dihydrogen phosphate, disodium hydrogen phosphate, trisodium phosphate, potassium dihydrogen phosphate, dipotassium hydrogen phosphate, sodium chloride, potassium chloride, sodium sulfate, magnesium sulfate, sodium benzoate, potassium sorbate, parabens, tocopherol, and ascorbic acid, and preferably may include one or more selected from distilled water, ethanol, glycerin, and propylene glycol, and more preferably may include distilled water.

[0036] Furthermore, the industrial deodorizer composition of the present invention may comprise, based on the total weight%, 3 to 10 weight% of pomegranate extract, 5 to 8 weight% of turmeric extract, 0.5 to 15 weight% of water-soluble polymer, 0.1 to 5 weight% of emulsifier, and 60 to 90 weight% of excipient.

[0037] Specifically, the industrial deodorizer composition of the present invention may comprise, based on the total weight percentage, 3 to 6.5 weight% of pomegranate extract, preferably 3 to 5.6 weight%, 5 to 9.0 weight% of turmeric extract, preferably 5 to 8.0 weight%, 0.5 to 15 weight% of water-soluble polymer, 0.1 to 5 weight% of emulsifier, and 60 to 90 weight% of excipients. If the composition falls outside this weight percentage range, there may be a problem in that it does not satisfy both excellent deodorizing effect and excellent antiviral activity.

[0038] In addition, the weight ratio of the pomegranate extract and the turmeric extract may be in the range of 1:1.0 to 1:2.6, preferably in the range of 1:1.5 to 1:2.5, and most preferably in the range of 1:1.5 to 1:2.0. If the weight ratio falls outside the above range, the synergistic effect between the ellagic acid of the pomegranate extract and the curcumin of the turmeric extract may be reduced, which may result in a decrease in deodorizing performance.

[0039] Meanwhile, the method for manufacturing the industrial deodorizer composition of the present invention is as follows.

[0040] First, the pomegranate fruit is washed and crushed, then extracted using 60% to 80% ethanol for 12 to 48 hours. Subsequently, a pomegranate extract with an ellagic acid content of 10 to 20% is prepared through filtration and concentration processes. Preferably, extraction is performed using 70% ethanol for 24 hours, and more preferably, a pomegranate extract with an ellagic acid content of 15% or more is prepared.

[0041] Next, the turmeric rhizome is washed, dried, and then ground, and hot water extraction is performed at 50°C to 70°C. Subsequently, the turmeric extract is freeze-dried to produce a curcumin content of 20-30%. Preferably, extraction is performed at 60°C for 68 hours, and more preferably, a turmeric extract with a curcumin content of 25% or more is produced.

[0042] If necessary, the prepared pomegranate extract and turmeric extract may be pretreated with herbal extracts. The pomegranate extract and turmeric extract are each immersed in an aqueous solution of lavender extract or rosemary extract at a concentration of 0.05 to 0.2% and aged at a low temperature of 2°C to 8°C for 4 to 12 hours. Afterward, the supernatant is recovered by centrifugation (2,000 rpm to 5,000 rpm, 5 to 20 minutes). Preferably, the extracts are treated in an aqueous solution of herbal extract at a concentration of 0.1% at 4°C for 6 hours, and more preferably, a combined treatment with lavender and rosemary is performed.

[0043] Next, a first mixture is prepared by mixing the pretreated pomegranate extract and turmeric extract with a water-soluble polymer in a set weight ratio. At this time, to ensure homogeneous mixing, the mixture is stirred at 500 to 1,500 rpm for 30 minutes to 2 hours.

[0044] Next, an emulsifier is added to the first mixture and stirred at 1,000 to 3,000 rpm for 1 to 3 hours. During this process, the emulsifier stabilizes the active ingredients of the pomegranate and turmeric extracts and improves dispersibility.

[0045] Then, add excipients and mix at 500 to 1,000 rpm for 2 to 4 hours. At this time, add the excipients in stages to prevent sedimentation or coagulation.

[0046] Finally, a final deodorant composition is prepared by performing a homogenization treatment using a high-pressure homogenizer (5,000 to 15,000 psi) or an ultrasonic homogenizer (20 to 40 kHz). Preferably, the homogenization treatment is performed at least three times at 10,000 psi.

[0047] The manufactured industrial deodorizer composition exhibits a high deodorization rate against malodorous substances such as ammonia, trimethylamine, methyl mercaptan, and hydrogen sulfide, and shows high antiviral activity against influenza viruses, etc. In addition, it has excellent persistence, maintaining its initial deodorization performance even after 24 hours.

[0049] Although the present invention has been described above with reference to embodiments, this is merely illustrative and does not limit the embodiments of the present invention. Those skilled in the art will understand that various modifications and applications not exemplified above are possible within the scope of the essential characteristics of the present invention. For example, each component specifically shown in the embodiments of the present invention may be modified and implemented. Furthermore, differences related to such modifications and applications should be interpreted as being included within the scope of the present invention as defined in the appended claims.

[0051] Example 1: Preparation of an industrial deodorizer composition

[0052] A pomegranate extract containing 15% ellagic acid was obtained by extracting pomegranate fruit with 70% ethanol for 24 hours and then concentrating it. A turmeric extract containing 25% curcumin was prepared by extracting turmeric rhizomes with hot water at 60°C and then freeze-drying them. An industrial deodorizer composition was prepared by mixing 3.7% by weight of pomegranate extract, 7.4% by weight of turmeric extract, 8% by weight of polyvinyl alcohol (PVA), and 2% by weight of Tween 80 so that the pomegranate extract and turmeric extract were blended in a weight ratio of 1:2, and then adding 78.9% by weight of purified water and homogenizing the mixture.

[0054] Example 2: Preparation of an industrial deodorizer composition

[0055] The pomegranate extract and turmeric extract prepared by the method of Example 1 were pretreated as follows. The pomegranate extract and turmeric extract were each immersed in a 0.1% aqueous solution of lavender extract and aged at 4°C for 6 hours, after which the supernatant was recovered by centrifugation (3,000 rpm, 10 min). Through this pretreatment, the linalool and linalyl acetate components of lavender were allowed to bind to the active components of the pomegranate and turmeric extracts to stabilize them.

[0056] An industrial deodorizer composition was prepared by mixing 3.7% by weight of pomegranate extract, 7.4% by weight of turmeric extract, 8% by weight of polyvinyl alcohol (PVA), and 2% by weight of Tween 80 so that the pretreated pomegranate extract and turmeric extract were blended in a weight ratio of 1:2, and then adding 78.9% by weight of purified water.

[0058] Example 3: Preparation of an industrial deodorizer composition

[0059] The pomegranate extract and turmeric extract prepared by the method of Example 1 were pretreated as follows. The pomegranate extract and turmeric extract were each immersed in a 0.1% aqueous solution of rosemary extract and aged at 4°C for 6 hours, after which the supernatant was recovered by centrifugation (3,000 rpm, 10 min). Through this pretreatment, the rosmarinic acid and carnosol components of rosemary interacted with the polyphenol compounds of pomegranate and turmeric to enhance antioxidant activity.

[0060] An industrial deodorizer composition was prepared by mixing 3.7% by weight of pomegranate extract, 7.4% by weight of turmeric extract, 8% by weight of polyvinyl alcohol (PVA), and 2% by weight of Tween 80 so that the pretreated pomegranate extract and turmeric extract were blended in a weight ratio of 1:2, and then adding 78.9% by weight of purified water.

[0062] Example 4: Preparation of an industrial deodorizer composition

[0063] The pomegranate extract and turmeric extract prepared by the method of Example 1 were subjected to complex pretreatment as follows. The pomegranate extract and turmeric extract were each immersed in aqueous solutions with concentrations of 0.1% lavender extract and 0.1% rosemary extract, respectively, and aged at low temperature at 4°C for 6 hours. Afterward, the supernatant was recovered by centrifugation (3,000 rpm, 10 minutes). Through this complex pretreatment, the complementary bioactive components of lavender and rosemary were combined optimally with the pomegranate and turmeric extracts to produce a synergistic effect.

[0064] An industrial deodorizer composition was prepared by mixing 3.7% by weight of pomegranate extract, 7.4% by weight of turmeric extract, 8% by weight of polyvinyl alcohol (PVA), and 2% by weight of Tween 80 so that the pretreated pomegranate extract and turmeric extract were blended in a weight ratio of 1:2, and then adding 78.9% by weight of purified water.

[0066] Example 5: Preparation of an industrial deodorizer composition

[0067] An industrial deodorizer composition was prepared by mixing 4.4% by weight of pomegranate extract, 6.7% by weight of turmeric extract, 8% by weight of polyvinyl alcohol (PVA), and 2% by weight of Tween 80 so that the pomegranate extract prepared by the method of Example 1 and the turmeric extract were blended in a weight ratio of 1:1.5, and then adding 78.9% by weight of purified water and homogenizing the mixture.

[0069] Example 6: Preparation of an industrial deodorizer composition

[0070] An industrial deodorizer composition was prepared by mixing 3.2% by weight of pomegranate extract, 7.9% by weight of turmeric extract, 8% by weight of polyvinyl alcohol (PVA), and 2% by weight of Tween 80 so that the pomegranate extract prepared by the method of Example 1 and the turmeric extract were blended in a weight ratio of 1:2.5, and then adding 78.9% by weight of purified water and homogenizing the mixture.

[0072] Example 7: Preparation of an industrial deodorizer composition

[0073] An industrial deodorizer composition was prepared by mixing 5.6% by weight of pomegranate extract, 5.5% by weight of turmeric extract, 8% by weight of polyvinyl alcohol (PVA), and 2% by weight of Tween 80 so that the pomegranate extract and turmeric extract prepared by the method of Example 1 were blended in a weight ratio of 1:1.0, and then adding 78.9% by weight of purified water and homogenizing the mixture.

[0075] Example 8: Preparation of an industrial deodorizer composition

[0076] An industrial deodorizer composition was prepared by mixing 3.1 wt% of pomegranate extract, 8.0 wt% of turmeric extract, 8 wt% of polyvinyl alcohol (PVA), and 2 wt% of Tween 80 so that the pomegranate extract and turmeric extract prepared by the method of Example 1 were blended in a weight ratio of 1:2.6, and then adding 78.9 wt% of purified water and homogenizing the mixture.

[0078] Comparative Example 1: Preparation of an industrial deodorizer composition

[0079] Only the pomegranate extract prepared by the method of Example 1 was used. A deodorant composition was prepared by mixing 11.1 wt% of pomegranate extract, 8 wt% of polyvinyl alcohol (PVA), and 2 wt% of Tween 80, and then adding 78.9 wt% of purified water.

[0081] Comparative Example 2: Preparation of an industrial deodorizer composition

[0082] Only the turmeric extract prepared by the method of Example 1 was used. A deodorant composition was prepared by mixing 11.1 wt% of turmeric extract, 8 wt% of polyvinyl alcohol (PVA), and 2 wt% of Tween 80, and then adding 78.9 wt% of purified water.

[0084] Comparative Example 3: Preparation of an industrial deodorizer composition

[0085] A pomegranate extract and a turmeric extract prepared by the method of Example 1 were mixed in a weight ratio of 1:0.5. A deodorant composition was prepared by mixing 7.4 wt% of pomegranate extract, 3.7 wt% of turmeric extract, 8 wt% of polyvinyl alcohol (PVA), and 2 wt% of Tween 80, and then adding 78.9 wt% of purified water and homogenizing the mixture.

[0087] Comparative Example 4: Preparation of an industrial deodorizer composition

[0088] A pomegranate extract and a turmeric extract prepared by the method of Example 1 were mixed in a weight ratio of 1:3.5. A deodorant composition was prepared by mixing 2.5 wt% of pomegranate extract, 8.6 wt% of turmeric extract, 8 wt% of polyvinyl alcohol (PVA), and 2 wt% of Tween 80, and then adding 78.9 wt% of purified water and homogenizing the mixture.

[0090] Comparative Example 5: Preparation of an industrial deodorizer composition

[0091] A pomegranate extract and a turmeric extract prepared by the method of Example 1 were mixed in a weight ratio of 1:0.1. A deodorant composition was prepared by mixing 10.1 wt% of pomegranate extract, 1.0 wt% of turmeric extract, 8 wt% of polyvinyl alcohol (PVA), and 2 wt% of Tween 80, and then adding 78.9 wt% of purified water and homogenizing the mixture.

[0093] Comparative Example 6: Preparation of an industrial deodorizer composition

[0094] An industrial deodorizer composition was prepared by mixing 2.8% by weight of pomegranate extract, 8.3% by weight of turmeric extract, 8% by weight of polyvinyl alcohol (PVA), and 2% by weight of Tween 80 so that the pomegranate extract prepared by the method of Example 1 and the turmeric extract were blended in a weight ratio of 1:3.0, and then adding 78.9% by weight of purified water and homogenizing the mixture.

[0096] Comparative Example 7: Preparation of a commercially available chemical deodorizer

[0097] A commercially available ammonia-based chemical deodorizer (main components: 15% aqueous ammonia solution, 5% surfactant, 2% preservative, 3% fragrance, 75% purified water) was used as a control group. The above chemical deodorizer operates by an immediate deodorization method through an ammonia neutralization reaction, which is a method widely used in industrial settings.

[0099] Experimental Example 1: Evaluation of Deodorizing Effect

[0100] The deodorizing effect of the compositions of Examples 1 to 8 and Comparative Examples 1 to 7 against ammonia, trimethylamine, methyl mercaptan, and hydrogen sulfide was evaluated. Each malodorous substance was injected into a sealed test chamber (capacity 10 L) at a concentration of 500 ppm, and then 10 ml of each composition was sprayed. After 30 minutes, the residual odor concentration was measured by GC-MS. The deodorization rate was calculated using the following formula: Deodorization rate (%) = (Initial concentration - Residual concentration) / Initial concentration × 100.

[0102] Deodorization rate by odor substance for each composition (Unit: %) division ammonia trimethylamine Methyl mercaptan hydrogen sulfide Average deodorization rate Example 1 92.3 88.7 94.8 91.2 91.8 Example 2 93.8 90.1 96.2 92.7 93.2 Example 3 94.1 90.4 96.5 93.1 93.5 Example 4 97.5 94.2 98.9 96.1 96.7 Example 5 95.2 91.9 97.1 94.4 94.7 Example 6 89.7 86.3 92.4 88.9 89.3 Example 7 87.4 83.8 90.1 86.5 86.9 Example 8 88.9 85.2 91.6 87.8 88.4 Comparative Example 1 71.3 68.9 74.2 69.8 71.1 Comparative Example 2 69.8 66.4 72.5 67.9 69.2 Comparative Example 3 76.2 72.8 78.9 75.1 75.8 Comparative Example 4 83.4 79.6 86.1 82.3 82.9 Comparative Example 5 68.1 64.7 70.3 66.9 67.5 Comparative Example 6 81.9 78.2 84.5 80.7 81.3 Comparative Example 7 85.2 82.1 87.3 84.6 84.8

[0104] As a result, the composition prepared by the method of Example 1 showed a deodorization rate of 92.3% for ammonia, and deodorization rates of 88.7% for trimethylamine, 94.8% for methyl mercaptan, and 91.2% for hydrogen sulfide. Examples 2 and 3 showed superior deodorization rates due to the single herb pretreatment effects of lavender and rosemary, respectively; in particular, the lavender and rosemary complex herb pretreatment composition of Example 4 achieved the highest deodorization rate with an average of 96.7%. Example 5 (1:1.5 weight ratio) showed excellent performance with an average of 94.7%, but exhibited relatively lower performance compared to Example 4. Examples 6 to 8 showed relatively low deodorization rates, and Comparative Examples 1 and 2, which used the extract prepared by the method of Example 1 alone, showed significantly lower deodorization rates of 71.1% and 69.2%, respectively.

[0106] Experimental Example 2: Evaluation of Antiviral Activity

[0107] The antiviral activity against influenza virus H1N1 and parainfluenza virus type 3 was evaluated for the compositions of Examples 1 to 8 and Comparative Examples 1 to 7. Virus suspension (10 6Each composition was mixed with (PFU / ml) in a 1:1 ratio and reacted at 37°C for 30 minutes, after which the viral infection value was measured using the Plaque Forming Unit (PFU) method. The viral inactivation rate was calculated using the following formula: Inactivation rate (%) = (Number of viruses in control group - Number of viruses in treatment group) / Number of viruses in control group × 100.

[0109] Inactivation rate of each composition by virus type (Unit: %) division Influenza virus H1N1 Parainfluenza virus type 3 Average inactivation rate Example 1 97.8 95.4 96.6 Example 2 98.2 96.1 97.2 Example 3 98.5 96.4 97.5 Example 4 99.4 98.2 98.8 Example 5 98.9 97.5 98.2 Example 6 95.7 93.2 94.5 Example 7 94.1 91.6 92.9 Example 8 95.3 92.8 94.1 Comparative Example 1 78.4 75.9 77.2 Comparative Example 2 76.8 74.3 75.6 Comparative Example 3 82.7 80.1 81.4 Comparative Example 4 89.4 86.9 88.2 Comparative Example 5 74.2 71.8 73.0 Comparative Example 6 87.9 85.3 86.6 Comparative Example 7 45.2 42.8 44.0

[0111] Experimental Example 3: Evaluation of Deodorizing Effect Duration

[0112] The persistence of the deodorizing effect was evaluated for the compositions of Examples 1 to 8 and Comparative Examples 1 to 7. For the persistence evaluation, the residual deodorizing effect was measured at 6, 12, and 24 hours after the initial spraying.

[0114] Evaluation of Deodorizing Effect Duration (Ammonia Standard, Unit: %) division beginning 6 hours later 12 hours later 24 hours later 24-hour persistence rate* Example 1 92.3 86.4 81.7 78.2 84.7 Example 2 93.8 88.2 84.1 81.3 86.7 Example 3 94.1 88.7 84.8 82.1 87.2 Example 4 97.5 93.1 90.8 89.2 91.5 Example 5 95.2 90.4 87.1 84.8 89.1 Example 6 89.7 82.3 77.8 74.1 82.6 Example 7 87.4 79.8 75.2 71.3 81.6 Example 8 88.9 81.7 77.4 73.9 83.1 Comparative Example 1 71.3 63.2 56.8 49.4 69.3 Comparative Example 2 69.8 61.5 54.9 47.6 68.2 Comparative Example 3 76.2 67.8 61.2 54.7 71.8 Comparative Example 4 83.4 74.9 68.1 61.8 74.1 Comparative Example 5 68.1 59.4 52.6 45.1 66.2 Comparative Example 6 81.9 73.2 66.4 59.8 73.0 Comparative Example 7 85.2 68.4 52.1 38.6 45.3

[0115] * Duration Rate = (Deodorization Rate after 24 hours / Initial Deodorization Rate) × 100

[0117] As a result of the persistence evaluation, the lavender and rosemary complex herb pretreatment composition of Example 4 showed the best persistence, maintaining 91.5% of the initial deodorization rate even after 24 hours. Example 5 (1:1.5 weight ratio) also showed a high persistence rate of 89.1%, but showed relatively lower persistence compared to Example 4. The single herb pretreatment compositions of Examples 2 and 3 also showed excellent persistence rates of 86.7% and 87.2%, respectively. On the other hand, Examples 6 to 8, which fell outside the scope of Claim 3, showed relatively low persistence. The persistence of the comparative examples was significantly low; in particular, Comparative Examples 1 and 2, which used a single extract, showed low persistence rates of 69.3% and 68.2%, respectively. Comparative Example 7, a chemical deodorizer, showed an initial deodorization effect but exhibited a rapid decline in performance to 45.3% after 24 hours, confirming that its persistence was very insufficient.

[0119] Overall, among the compositions using the extract prepared by the standard extraction method of Example 1, Example 4, which applied a complex herbal pretreatment of lavender and rosemary, showed the best performance in all evaluation categories. Example 4 achieved the highest performance with an average deodorization rate of 96.7%, an average antiviral activity of 98.8%, and a persistence rate of 91.5%. On the other hand, Comparative Examples 1 and 2, which used the extract prepared by the method of Example 1 alone, showed significantly lower inactivation rates of 77.2% and 75.6%, respectively. This is attributed to a mechanism in which ellagic acid and anthocyanin from the pomegranate extract prepared by the standard extraction method of Example 1, and curcumin and turmeron from the turmeric extract, effectively bind to viral envelope proteins when combined in appropriate proportions, thereby blocking viral cell invasion and inhibiting replication.

Claims

Claim 1 An industrial deodorizer composition characterized by comprising 3 to 10 weight% of pomegranate extract, 5 to 8 weight% of turmeric extract, 0.5 to 15 weight% of water-soluble polymer, 0.1 to 5 weight% of emulsifier, and 60 to 90 weight% of excipient, wherein the pomegranate extract and turmeric extract are pretreated with one or more herb extracts selected from the group consisting of lavender extract and rosemary extract. Claim 2 delete Claim 3 An industrial deodorizer composition according to claim 1, characterized in that the weight ratio of the pomegranate extract to the turmeric extract is 1:1.0 to 1:2.

6. Claim 4 An industrial deodorizer composition according to claim 1, characterized in that the pomegranate extract is extracted from pomegranate fruit or pomegranate peel and contains ellagic acid and anthocyanin as active ingredients, and the turmeric extract is extracted from rhizome and contains curcumin and turmerone as active ingredients. Claim 5 An industrial deodorizer composition according to claim 1, characterized in that the composition exhibits a deodorizing effect for one or more selected from the group consisting of ammonia, trimethylamine, methyl mercaptan, and hydrogen sulfide. Claim 6 An industrial deodorizer composition according to claim 1, characterized in that the water-soluble polymer is one or more selected from the group consisting of polyvinyl alcohol (PVA), gelatin, carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC), sodium alginate, pectin, chitosan, carrageenan, and xanthan gum. Claim 7 An industrial deodorizer composition according to claim 1, characterized in that the emulsifier is one or more selected from the group consisting of sodium stearate, sodium oleate, sodium laurate, sorbitan monooleate, sorbitan monostearate, polyethylene glycol monostearate, glycerin monostearate, Tween 20, Tween 60, Tween 80, poloxamer, and lecithin. Claim 8 An industrial deodorizer composition according to claim 1, characterized in that the excipient comprises one or more selected from the group consisting of distilled water, ethanol, palm oil, glycerin, propylene glycol, butylene glycol, sorbitol, mannitol, citric acid, sodium citrate, sodium dihydrogen phosphate, disodium hydrogen phosphate, sodium chloride, sodium sulfate, and sodium benzoate. Claim 9 An industrial deodorizer composition according to claim 1, wherein the composition has antiviral activity, and the antiviral has antiviral activity against one or more viruses selected from the group consisting of influenza virus, coronavirus (SARS-CoV-2), norovirus, rotavirus, adenovirus, rhinovirus, enterovirus, RSV (Respiratory Syncytial Virus), and parainfluenza virus. Claim 10 A method for preparing an industrial deodorizer composition according to claim 1, characterized by comprising the following steps, wherein in steps (a) and (b) below, the pomegranate extract and the turmeric extract are pretreated with one or more herbal extracts selected from the group consisting of lavender extract and rosemary extract: (a) a step of preparing a pomegranate extract by hot water extraction or ethanol extraction from a pomegranate; (b) a step of preparing a turmeric extract by hot water extraction or ethanol extraction from a turmeric; (c) a step of preparing a primary mixture by mixing 3 to 10 weight% of the pomegranate extract and 5 to 8 weight% of the turmeric extract with 0.5 to 15 weight% of a water-soluble polymer; (d) a step of adding 0.1 to 5 weight% of an emulsifier to the primary mixture and stirring and mixing; (e) a step of adding 60 to 90 weight% of an excipient and mixing; and (f) a step of preparing a deodorant composition by homogenization treatment. Claim 11 delete Claim 12 A method for manufacturing an industrial deodorizer composition according to claim 10, wherein the herb extract pretreatment is characterized by immersing pomegranate extract and turmeric extract, respectively, in an aqueous solution of herb extract at a concentration of 0.05 to 0.2%, aging them at a low temperature of 2°C to 8°C for 4 to 12 hours, and then centrifuging (2,000 rpm to 5,000 rpm, 5 to 20 minutes) to recover the supernatant. Claim 13 A method for preparing an industrial deodorizer composition according to claim 10, wherein in step (a), the pomegranate extract is prepared by extracting from pomegranate fruit using 60% to 80% ethanol for 12 to 48 hours and then concentrating, and in step (b), the turmeric extract is prepared by extracting from turmeric rhizomes with hot water at 50°C to 70°C and then freeze-drying.