Skin drug delivery system hybrid iontopheresis and ultrasonic energy

Abstract

The present invention relates to a skin drug delivery system that fuses iontophoresis and ultrasonic energy. More specifically, by providing a skin drug delivery system that fuses iontophoresis—which transmits ions into tissues within the body using microcurrents—with ultrasonic energy, the invention enables improved drug injection efficiency, such as minimizing the loss of drugs injected into the skin. Furthermore, by measuring the skin condition of a patient and utilizing this measurement data to optimize whether to inject drugs and the method of drug injection based on artificial intelligence, the invention enables the application of the most suitable skin drug delivery method for each patient. Additionally, by allowing real-time monitoring of the drug injection status and process, the invention enables further improvement of not only drug injection efficiency but also safety. Moreover, through the above-mentioned system, data such as the patient's skin data, measurement cycle, drug type, and major treatment method can be accumulated and verified, and by utilizing this data, customized skin care solutions such as acne management, wrinkle removal, and skin tone improvement can be provided.

Description

Technology Field

[0001] The present invention relates to a skin drug delivery system capable of improving drug injection efficiency, such as minimizing drug loss when injected into the skin, by combining and applying iontopheresis, which uses microcurrents to transmit ions into body tissues, with ultrasonic energy. Background Technology

[0002] Lifelong health management is one of the biggest drivers of high growth in the aesthetic medical device market. Demand is high, centered on developed countries such as the United States and Europe, and related needs are expected to continue increasing both domestically and internationally in the future.

[0003] Moreover, the global market for aesthetic medical devices is expected to grow most rapidly in the Asia-Pacific region due to increased consumer spending and the expansion of e-commerce, with the North American market leading the growth of the entire global market as it expands under the leadership of e-commerce companies such as Amazon and Sephora (Global Healthcare Industry Trends, No. 469, 2023).

[0004] Meanwhile, among cosmetic medical devices, there is growing interest in skin cosmetic medical devices capable of effectively delivering transdermal drugs to the skin, and for such devices, technology is required to inject the drug into the skin while minimizing drug loss.

[0005] In this regard, conventional electric needle drug delivery devices such as Patent Document 1 have a problem in that they are not properly injected into the skin when injecting drugs, resulting in an average drug loss of 30%.

[0006] In addition, various technologies that apply microcurrents, ultrasound, etc., to the skin individually or in combination to improve this have been disclosed, but there is a problem in that the drug delivery efficiency does not reach a satisfactory level. Prior art literature

[0007] Patent Document 1: Korean Published Patent Application No. 10-2009-0079714 Patent Document 2: Korean Published Patent Application No. 10-2005-0121277 Patent Document 3: Korean Published Patent Application No. 10-2017-0063829 Patent Document 4: Korean Published Patent Application No. 10-2024-0006756 Patent Document 5: Korean Registered Patent Application No. 10-2280321 Patent Document 6: Korean Registered Patent Application No. 10-2280320 Patent Document 7: Korean Registered Patent Application No. 10-2460637 Patent Document 8: Korean Registered Patent Application No. 10-2460637 The problem to be solved

[0008] The present invention aims to solve the above-mentioned problems by providing a skin drug delivery system that combines ionophoresis, which transmits ions into body tissues using microcurrents, with ultrasonic energy, thereby improving drug injection efficiency, such as minimizing the loss of drugs injected into the skin.

[0009] In addition, the objective is to measure the skin condition of the patient and utilize this measurement data to optimize whether to inject drugs and the method of drug injection based on artificial intelligence, thereby enabling the application of the most suitable skin drug delivery method for each patient, as well as to further improve not only the efficiency of drug injection but also safety by enabling real-time monitoring of the drug injection status and process.

[0010] In addition, the objective is to enable the accumulation and verification of data such as the skin data, measurement cycle, drug type, and main treatment methods of the subject through the aforementioned system, and to utilize this data to provide customized skin care solutions, such as acne management, wrinkle removal, and skin tone improvement.

[0011] The problems that the present invention aims to solve are not limited to those mentioned above, and other problems that the present invention aims to solve that are not mentioned herein will be clearly understood by those skilled in the art to which the present invention belongs from the description below. means of solving the problem

[0012] The present invention comprises: a skin condition measuring unit (100) that measures the skin condition of a subject and generates skin condition signal information; a skin condition judgment unit (200) that receives the skin condition signal information measured by the skin condition measuring unit (100) and generates drug injection judgment signal information for the subject based on the received skin condition signal information; and a drug injection unit (300) that receives the drug injection judgment signal information determined by the skin condition judgment unit (200), injects a drug into the skin according to the received drug injection judgment signal information, and generates drug injection state signal information as the drug is injected. and a monitoring unit (400) that receives drug injection status signal information generated from the drug injection unit (300), monitors the received drug injection status signal information, and notifies the practitioner; wherein the skin condition measuring unit (100) includes a skin measuring sensor that detects the skin condition by contacting the skin of the subject, and the skin condition judgment unit (200) includes a learning module (210) that stores and learns skin condition signal information measured by the skin condition measuring unit (100) for a certain period of time in a skin condition where drug injection is not required; and a judgment module (220) that generates drug injection judgment signal information including whether to inject drugs and a method of drug injection for a patient by comparing skin condition signal information learned by the learning module (221) and skin condition signal information generated in real time by the skin condition measuring unit (100); wherein the drug injection unit (300) is a means for injecting drugs by adhering to the skin of a patient, and comprises a handpiece unit (310) including an ultrasonic handpiece unit (311) including an ultrasonic element that emits an ultrasonic vibration frequency of 3 MHz or 10 MHz and an iontophoresis handpiece unit (312) including an electrode that emits a frequency of 28 kHz;The skin drug delivery system fused with iontophoresis and ultrasonic energy is provided as a means of solving the problem, characterized by including: skin condition signal information generated by the skin condition measuring unit (100); drug injection judgment signal information including whether to inject drugs and a drug injection method generated by the skin condition judgment unit (200); drug injection status signal information generated by the drug injection unit (300); and a display unit (320) that displays monitoring information of the monitoring unit (400) based on the drug injection status signal information to the operator.

[0013] Here, the judgment module (220) may include: a skin condition signal information storage unit (220-1) in which learned skin condition signal information and real-time generated skin condition signal information are stored; a change value calculation unit (220-2) that calculates a change value by substituting the real-time generated skin condition signal information into the learned skin condition signal information; and a state derivation unit (220-3) that generates drug injection judgment signal information including whether to inject drugs and the method of drug injection for a patient by substituting the change value into previously learned state classification information.

[0014] And the monitoring unit (400) may include: a notification information determining unit (410) that generates notification information determining a character, color, sound, or number to display the drug injection status signal information based on a display classification for each classified status information corresponding to the drug injection status signal information generated in the drug injection unit (300); and a notification unit (420) that provides the notification information to the display unit (320) of the drug injection unit (300). Effects of the invention

[0015] The present invention provides a skin drug delivery system that combines iontophoresis and ultrasonic energy, thereby having the effect of improving drug injection efficiency, such as minimizing the loss of drugs injected into the skin.

[0016] In addition, by measuring the skin condition of the patient and utilizing this measurement data to optimize whether to inject drugs and the method of drug injection based on artificial intelligence, it is possible to apply the most suitable skin drug delivery method for each patient, and by enabling real-time monitoring of the drug injection status and process, it is possible to further improve not only the efficiency of drug injection but also safety.

[0017] In addition, the aforementioned system enables the accumulation and verification of data regarding the subject's skin, measurement cycle, drug type, and main treatment methods, and by utilizing this, it is possible to provide customized skin care solutions such as acne management, wrinkle removal, and skin tone improvement. Brief explanation of the drawing

[0018] FIG. 1 is a block diagram showing the overall configuration of a skin drug delivery system according to the present invention. FIG. 2 is a block diagram illustrating a skin condition determination unit according to the present invention. FIG. 3 is a block diagram illustrating a drug injection unit according to the present invention. FIG. 4 is a block diagram illustrating a monitoring unit according to the present invention. FIG. 5 is a block diagram illustrating the overall configuration of a skin drug delivery system according to the present invention. FIG. 6 is a drawing embodying an ultrasonic handpiece part according to the present invention. FIG. 7 is a drawing illustrating an iontophoresis handpiece portion according to the present invention. Specific details for implementing the invention

[0019] The advantages and features of the embodiments of the present invention, and the methods for achieving them, will become clear by referring to the embodiments described below in detail together with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below but may be implemented in various different forms. These embodiments are provided merely to ensure that the disclosure of the present invention is complete and to fully inform those skilled in the art of the scope of the invention, and the present invention is defined only by the scope of the claims. Throughout the specification, the same reference numerals refer to the same components.

[0020] In describing the embodiments of the present invention, specific descriptions of known functions or configurations will be omitted if it is determined that such detailed descriptions could unnecessarily obscure the essence of the invention. Furthermore, the terms described below are defined in consideration of their functions in the embodiments of the present invention, and these definitions may vary depending on the intentions or practices of the user or operator. Therefore, such definitions should be based on the content throughout this specification.

[0021] Hereinafter, preferred embodiments of the present invention will be described with reference to the attached drawings.

[0022] FIG. 1 is a block diagram showing the overall configuration of a skin drug delivery system according to the present invention, FIG. 2 is a block diagram showing a skin condition judgment unit according to the present invention, FIG. 3 is a block diagram showing a drug injection unit according to the present invention, FIG. 4 is a block diagram showing a monitoring unit according to the present invention, FIG. 5 is a block diagram showing the overall configuration of a skin drug delivery system according to the present invention, FIG. 6 is a drawing showing an ultrasonic handpiece unit according to the present invention, and FIG. 7 is a drawing showing an iontophoresis handpiece unit according to the present invention.

[0023] Referring to FIGS. 1 to 7, the skin drug delivery system according to the present invention includes a skin condition measuring unit (100), a skin condition determining unit (200), a drug injection unit (300), and a monitoring unit (400).

[0024] The above skin condition measuring unit (100) measures the skin condition of a subject and generates skin condition signal information, and includes a skin measuring sensor that detects the skin condition by contacting the subject's skin.

[0025] Here, the skin measurement sensor described above can be equipped with various sensors capable of measuring skin moisture, oil, elasticity, temperature, wrinkles, degree of contamination, etc., and numerous such sensors are already publicly known. Furthermore, various publicly known sensors can be selectively applied without being limited to sensors of specific products or structures.

[0026] The skin condition judgment unit (200) receives skin condition signal information measured by the skin condition measurement unit (100) and generates drug injection judgment signal information for the subject based on the received skin condition signal information, and includes a learning module (210) and a judgment module (220).

[0027] More specifically, the skin condition signal information measured by the skin condition measuring unit (100) for a certain period in a skin condition where drug injection is not required is stored and learned through the learning module (210), and the skin condition signal information learned by the learning module (221) is compared with the skin condition signal information generated in real time by the skin condition measuring unit (100) through the judgment module (220) to generate drug injection judgment signal information including whether to inject drugs for the subject and the method of drug injection.

[0028] To this end, the judgment module (220) includes a skin condition signal information storage unit (220-1), a change value calculation unit (220-2), and a state derivation unit (220-3). More specifically, the learned skin condition signal information and the real-time generated skin condition signal information are stored in the skin condition signal information storage unit (220-1). The change value is calculated by substituting the real-time generated skin condition signal information into the learned skin condition signal information through the change value calculation unit (220-2). The change value is then substituted into the previously learned state classification information through the state derivation unit (220-3) to generate drug injection judgment signal information including whether to inject drugs into the subject and the method of drug injection.

[0029] Here, the above state classification information refers to information that is pre-learned to determine the state by classifying it into state A when the range of the change value is A, for example, when the change value is 10 or more, it refers to information classified as 'drug injection required' or 'use of iontophoresis handpiece'.

[0030] Meanwhile, the learning module (210) and the judgment module (220) can use known Artificial Intelligence (AI) modules. That is, it is possible to build an AIoT (Artificial Intelligence of Things) based system through the fusion of the various sensors and the AI ​​modules.

[0031] Here, the artificial intelligence module may be a CNN (Convolutional Neural Networks) model that includes an Inception module in a GAP (Global Average Pooling) layer.

[0032] The artificial intelligence module can produce desired data by learning the weights of multiple inputs through deep learning. In addition, various models such as RNN (Recurrent Neural Network), DNN (Deep Neural Network), and DRNN (Dynamic Recurrent Neural Network) can be utilized as artificial intelligence network models for this learning.

[0033] Here, RNN is a deep learning technique that considers current and past data simultaneously, and a Recurrent Neural Network (RNN) represents a neural network in which the connections between units constituting the artificial neural network form a directed cycle. Furthermore, various methods can be used for structures that can construct a Recurrent Neural Network (RNN); for example, representative examples include the Fully Recurrent Network, Hopfield Network, Elman Network, Echo State Network (ESN), Long Short-Term Memory Network (LSTM), Bi-directional RNN, Continuous-Time RNN (CTRNN), Hierarchical RNN, and Second-Order RNN. Additionally, methods such as Gradient Descent, Hessian Free Optimization, and Global Optimization Method can be used to train the Recurrent Neural Network (RNN).

[0034] Furthermore, conventional CNNs suffer from the problem of high processing speed and computational load. Since the present invention requires iterative computation using immediate additional data, a lighter algorithm is necessary. Therefore, Global Average Pooling (GAP) layers and Inception modules can be applied to the CNN model. Generally, CNNs stack many convolution layers, resulting in a large number of filters. A large number of filters implies that feature maps accumulate accordingly. In other words, it means that the dimensionality of the CNN is very high.

[0035] Handling high dimensions requires a large number of parameters capable of handling them. However, if the number of parameters becomes too large, problems such as overfitting can occur during training. Therefore, a method is needed to reduce dimensionality by decreasing the number of parameters used in the filters. The layer in CNNs that performs this role is the pooling layer.

[0036] In this case, GAP solves this problem by extracting the average from each feature and moving it directly to the classification layer. Consequently, because it directly associates features with categories while preserving the spatial information of the previous feature maps, it can generate a confidence map (= feature map) that indicates which parts of the obtained feature maps played a major role in classifying them into a specific class. Since it does not require separate parameter optimization, it has the advantage of low computational load and the ability to prevent overfitting.

[0037] The Inception architecture is a form in which a small neural network is added inside a neural network, and the small neural network inside is called the Inception module. The Inception module can reduce the feature map through 1x1 convolution, making it effective in terms of processing speed and computational load.

[0038] Accordingly, the above artificial intelligence module may apply a CNN model including an Inception module to the GAP (Global Average Pooling) layer.

[0039] In addition, each communication unit described above or below may utilize Bluetooth, ZigBee, Ultra WideBand (UWB), or Wi-Fi.

[0040] The above drug injection unit (300) receives drug injection judgment signal information determined by the skin condition judgment unit (200), injects a drug into the skin according to the received drug injection judgment signal information, and generates drug injection status signal information as the drug is injected. The above drug injection unit (300) includes a handpiece unit (310) and a display unit (320).

[0041] More specifically, the handpiece part (310) is a means for injecting drugs by adhering to the skin of a patient, and includes an ultrasonic handpiece part (311) including an ultrasonic element that emits an ultrasonic vibration frequency of 3 MHz or 10 MHz, and an iontophoresis handpiece part (312) including an electrode that emits a frequency of 28 kHz.

[0042] Here, the injection of the drug is performed by operating the handpiece by the operator. That is, after the operator confirms the drug injection judgment signal information determined by the skin condition judgment unit (200) through the display unit (320), the operator operates the handpiece to correspond to the information, thereby injecting the drug.

[0043] In addition, the display unit (320) displays to the operator skin condition signal information generated by the skin condition measurement unit (100), drug injection judgment signal information including whether to inject drugs and a drug injection method generated by the skin condition judgment unit (200), drug injection status signal information generated by the drug injection unit (300), and monitoring information of the monitoring unit (400) based on the drug injection status signal information.

[0044] Here, the iontophoresis handpiece (312) is a handpiece that includes an electrode oscillating at a frequency of 28 kHz for the application of iontophoresis, and the iontophoresis method is already known as a means for injecting drugs into the skin, as in Patent Documents 2 and 3, etc., and the application of the already known iontophoresis method is possible without being limited to a specific product or structure, and as an example, the iontophoresis handpiece (312) including an ion force module (312a) such as that in Patent Document 8, which was previously filed by the applicant of the present invention, can be used.

[0045] More specifically, the iontophoresis module (312a) can stimulate the skin using electro-iontophoresis and is equipped with an electrode part (312a-1, terminal part) and an iontophoresis handle part (312a-2) capable of flowing a microcurrent into the skin. The electrode part (312a-1) is coupled to one end of the iontophoresis handle part (312a-2) and is configured such that a direct current is applied through the electrode part (312a-1) to move an ionized positive or negative solvent to the skin tissue according to the skin condition, thereby providing acidic or alkaline effects to the skin and injecting a drug applied to the skin into the skin.

[0046] In addition, the above-mentioned ultrasonic handpiece part (311) can also be any of the various ultrasonic oscillating handpieces that are already known, but as an example, an ultrasonic handpiece including an ultrasonic vibration module (311a) such as that of Patent Document 8, which was previously filed by the applicant of the present invention, can be used.

[0047] More specifically, the ultrasonic vibration module (311a) is equipped with an ultrasonic element (311a-1, frequency vibration source) that generates ultrasonic vibration, a head portion (311a-2), and an ultrasonic handle portion (311a-3). Ultrasonic vibration is generated by the ultrasonic element (311a-1), and the head portion (311a-2) is coupled to one end to transmit the ultrasonic vibration to the head portion (311a-2). The head portion (311a-2) receives the vibration generated from the ultrasonic element (311a-1), vibrates, and comes into contact with the user's skin to transmit the ultrasonic vibration to the user's skin. And the ultrasonic handle portion (311a-3) may have an ultrasonic element (311a-1) inserted inside, and is configured to be combined with the head portion (311a-2) at first, and can transmit ultrasonic vibrations to the skin through the ultrasonic element (311a-1) and the head portion (311a-2) to inject a drug applied to the skin into the skin.

[0048] In addition, the device configuration of the drug injection unit (300) including the handpiece unit (310) and the display unit (320) may be applied such as the device configuration described in Patent Documents 4 to 7, which were previously filed by the applicant of the present invention.

[0049] Meanwhile, the drug injection status signal information resulting from the injection of the drug is information that is displayed as 'good' when the drug injection by the handpiece is performed smoothly in accordance with the preset dose, or 'bad' when it is not performed smoothly. This information may be displayed directly on the display unit (320), or may be displayed on the display unit (320) in the form of notification information through the monitoring unit (400).

[0050] The monitoring unit (400) receives drug injection status signal information generated from the drug injection unit (300), monitors the received drug injection status signal information, and notifies the operator, and includes a notification information determination unit (410) and a notification unit (420).

[0051] More specifically, based on a display classification by pre-classified status information corresponding to the drug injection status signal information generated in the drug injection unit (300), a character, color, sound, or number to display the drug injection status signal information is determined through the notification information determining unit (410) to generate notification information, and the notification information is provided to the display unit (320) of the drug injection unit (300) through the notification unit (420).

[0052] Here, the above-mentioned classification of display information by status information means that, depending on the status information, if it is in state A, A notification information is displayed, for example, when the drug injection status signal information is 'defective', display means such as text (check handpiece), color (blinking red), sound (warning sound), or number (numerical value of the degree of defect).

[0053] Accordingly, the present invention provides a skin drug delivery system that fuses iontophoresis and ultrasonic energy as described above, thereby improving drug injection efficiency by minimizing the loss of drugs injected into the skin. Furthermore, by measuring the skin condition of the patient and utilizing this measurement data to optimize whether to inject drugs and the method of drug injection based on artificial intelligence, the most suitable skin drug delivery method for each patient can be applied. Additionally, by enabling real-time monitoring of the drug injection status and process, not only can drug injection efficiency but also safety can be further improved. Moreover, through such a system, data such as the patient's skin data, measurement cycle, drug type, and main treatment method can be accumulated and verified, and by utilizing this, customized skin care solutions such as acne management, wrinkle removal, and skin tone improvement can be provided.

[0054] Meanwhile, in order to prevent each handpiece from slipping from the user's hand during the procedure, an anti-slip silicone resin-based foam cover may be placed on the outer surface of the iontophoresis handle (312a-2) and the ultrasonic handle (311a-3).

[0055] More specifically, the foam cover may be formed by mixing 100 parts by weight of a resin mixture in which silicone resin and polyurethane resin are mixed in a weight ratio of 1:1 to 2:1 as a base material, 2 to 4 parts by weight of an inorganic filler in which zeolite and calcium carbonate are mixed in a weight ratio of 1:1 to 2:1 as an inorganic filler for anti-slip purposes, 1 to 2 parts by weight of vinyltriethoxysilane as a dispersant to improve the dispersibility of the inorganic filler, 1 to 3 parts by weight of dicumyl peroxide as a crosslinking agent, and 1 to 3 parts by weight of azodicarbonamide as a foaming agent, and then foam molding the mixture into a cover shape.

[0056] In this case, if each of the above compositions and their contents deviate from the above range, there is a concern that the efficiency of improving anti-slip performance may decrease.

[0057] The present invention is not limited to the embodiments described above and has a diverse scope of application. Furthermore, it is understood that anyone with ordinary knowledge in the field to which the present invention pertains can make various modifications without departing from the essence of the invention as claimed in the claims. Explanation of the symbols

[0058] 100 : Skin condition measurement section 200 : Skin condition judgment unit 210 : Learning Module 220 : Judgment Module 220-1 : Skin condition signal information storage unit 220-2 : Change Value Calculation Unit 220-3 : State Derivation Section 300 : Drug infusion port 310: Handpiece section 311: Ultrasonic handpiece 311a : Ultrasonic vibration module 311a-1 : Ultrasonic element 311a-2 : Head section 311a-3 : Ultrasonic handle 312 : Iontophoresis handpiece 312a: Iontophoresis module 312a-1 : Electrode part 312a-2 : Ionophoresis handle 320 : Display section 400 : Monitoring Department 410 : Notification Information Determination Unit 420 : Notification Department

Claims

Claim 1 A skin condition measuring unit (100) that measures the skin condition of a patient and generates skin condition signal information; a skin condition judgment unit (200) that receives the skin condition signal information measured by the skin condition measuring unit (100) and generates drug injection judgment signal information for the patient based on the received skin condition signal information; and a drug injection unit (300) that receives the drug injection judgment signal information determined by the skin condition judgment unit (200), injects a drug into the skin according to the received drug injection judgment signal information, and generates drug injection state signal information as the drug is injected. and a monitoring unit (400) that receives drug injection status signal information generated from the drug injection unit (300), monitors the received drug injection status signal information, and notifies the practitioner; wherein the skin condition measuring unit (100) includes a skin measuring sensor that detects the skin condition by contacting the skin of the subject, and the skin condition judgment unit (200) includes a learning module (210) that stores and learns skin condition signal information measured by the skin condition measuring unit (100) for a certain period of time in a skin condition where drug injection is not required; and a judgment module (220) that generates drug injection judgment signal information including whether to inject drugs and a method of drug injection for a patient by comparing skin condition signal information learned by the learning module (210) and skin condition signal information generated in real time by the skin condition measuring unit (100); wherein the drug injection unit (300) is a means for injecting drugs by adhering to the skin of a patient, and comprises a handpiece unit (310) including an ultrasonic handpiece unit (311) including an ultrasonic element that emits an ultrasonic vibration frequency of 3 MHz or 10 MHz and an iontophoresis handpiece unit (312) including an electrode that emits a frequency of 28 kHz;A skin drug delivery system that fuses iontophoresis and ultrasonic energy, characterized by comprising: a skin condition signal information generated by the skin condition measuring unit (100); a drug injection judgment signal information including whether to inject drugs and a drug injection method generated by the skin condition judgment unit (200); a drug injection status signal information generated by the drug injection unit (300); and a display unit (320) that displays to the operator the monitoring information of the monitoring unit (400) based on the drug injection status signal information. Claim 2 In claim 1, the judgment module (220) comprises: a skin condition signal information storage unit (220-1) in which learned skin condition signal information and real-time generated skin condition signal information are stored; a change value calculation unit (220-2) that calculates a change value by substituting the real-time generated skin condition signal information into the learned skin condition signal information; and a state derivation unit (220-3) that generates drug injection judgment signal information including whether to inject drugs and a drug injection method for a subject by substituting the change value into previously learned state classification information. This characterizes a skin drug delivery system that fuses iontophoresis and ultrasonic energy. Claim 3 A skin drug delivery system that fuses iontophoresis and ultrasonic energy, characterized in that, in the first paragraph, the monitoring unit (400) comprises: a notification information determining unit (410) that generates notification information determining a character, color, sound, or number to display the drug injection status signal information based on a display classification for each classified status information corresponding to the drug injection status signal information generated in the drug injection unit (300); and a notification unit (420) that provides the notification information to the display unit (320) of the drug injection unit (300).

Images