Microrna induction of cardiac regeneration

MA39990AUndetermined Publication Date: 2015-11-19THE TRUSTEES OF THE UNIV OF PENNSYLVANIA

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Patent Information

Application Number: MA39990
Authority / Receiving Office: MA · MA
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2014-05-16
Filing Date: 2015-05-15
Publication Date: 2015-11-19

Application Information

Patent Timeline

16 May 2014

Priority

15 May 2015

Application

MA39990

19 Nov 2015

Publication

MA39990A

IPC: C12N15/00; C12N5/00; C12N5/02

CPC: C12N5/0657; C12N2501/65; C12N2510/00; C12N15/113; A01K2227/105; A01K2267/0375; C12N2740/15043; A61K31/19

Inventors: MORRISEY Edward E.

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Abstract

The invention relates to compostions and methods for promoting cellular proliferation and de-differentiation of cells into stem cells to foster tissue regeneration. Specifically, the invention relates to transiently administering a microrna (mir) or its mimic for promoting cardiomyocyte proliferation and cardiac regeneration.

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