Process for the purification of tnfr:fc fusion protein

MA40232AUndetermined Publication Date: 2017-04-19LUPIN LTD

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Patent Information

Application Number: MA40232
Authority / Receiving Office: MA · MA
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2014-06-13
Filing Date: 2015-06-13
Publication Date: 2017-04-19

Application Information

Patent Timeline

13 Jun 2014

Priority

13 Jun 2015

Application

MA40232

19 Apr 2017

Publication

MA40232A

IPC: C07K14/715

CPC: C07K14/7151; C07K2319/30; B01D15/12; B01D15/203; B01D15/30; B01D15/363; B01D15/3809; B01D15/3847

Inventors: BANERJEE Abir; GANAPATHY Chandranath

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Abstract

The present invention relates to the purification of tnfr:fc fusion protein. More specifically related to process of purification of tnfr:fc fusion protein wherein the hcp is reduced. The present invention is directed to the use of mixed-mode chromatography and / or affinity chromatography to produce tnfr:fc fusion protein which is substantially free of at least one of the protein degrading enzyme present in hcp.

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