NEW CHROMONE OXIME DERIVATIVE AND ITS USE AS AN ALLOSTERIC MODULATOR OF GLUTAMATE METABOTROPIC RECEPTORS

MA40530AUndetermined Publication Date: 2017-07-05PREXTON THERAPEUTICS
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Patent Information

Application Number
MA40530
Authority / Receiving Office
MA · MA
Patent Type
Applications
Current Assignee / Owner
Priority Date
2014-08-27
Filing Date
2015-08-27
Publication Date
2017-07-05
Patent Text Reader

Abstract

The present invention relates to a novel chromone oxime derivative of formula (i), which is a modulator of glutamate-sensitive receptors in the nervous system and, furthermore, which advantageously exhibits high penetration into the brain upon oral administration. The invention also relates to a pharmaceutical composition containing this compound and its use for the treatment or prevention of health conditions associated with altered glutamatergic signaling and / or function, or health conditions that can be influenced by changes in glutamate levels or signaling, particularly acute and chronic neurological and / or psychiatric disorders.
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