Antisense oligomers of tau protein and their uses

MA41586AUndetermined Publication Date: 2017-12-13F HOFFMANN LA ROCHE & CO AG

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Patent Information

Application Number: MA41586
Authority / Receiving Office: MA · MA
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2016-01-15
Filing Date: 2016-02-04
Publication Date: 2017-12-13

Application Information

Patent Timeline

15 Jan 2016

Priority

04 Feb 2016

Application

MA41586

13 Dec 2017

Publication

MA41586A

IPC: A61K31/712; A61P25/28

CPC: C12N2310/11; C12N2310/315; C12N2310/3231; C12N2310/341; C12N2310/343; C12N2310/346; C12N15/113; A61P25/28

Inventors: BROWN Jeffrey M.; CACACE Angela M.

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Abstract

The present invention relates to oligomeric compounds (oligomers) that target tau mRNA in a cell, leading to reduced expression of the tau protein. Reduced tau protein expression is beneficial for the treatment of certain medical conditions, such as neurological disorders.

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