VALBENAZINE DITOSYLATE AND ASSOCIATED POLYMORPHS
MA43116AActive Publication Date: 2018-09-05NEUROCRINE BIOSCIENCES INC
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Patent Information
- Application Number
- MA43116
- Authority / Receiving Office
- MA · MA
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2016-10-28
- Filing Date
- 2016-10-28
- Publication Date
- 2018-09-05
- Estimated Expiration
- 2036-10-28
AI Technical Summary
Technical Problem
However, the drawbacks to such treatment are the fluctuating response, the need for frequent intake do to TBZ rapid metabolism, and side effects.
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Abstract
The present invention relates to salts of the (2r,3r,11br)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,la]isoquinolin-2-yl of (s)-2-amino-3-methylbutyric acid in amorphous and crystalline forms, as well as methods for preparing and pharmaceutical compositions thereof. The invention also relates to methods of using these salts for the treatment, prevention, or alleviation of one or more symptoms of neurological disorders and diseases, including hyperkinetic disorders or diseases.
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