ANTI-EPHA4 ANTIBODIES
MA56466AActive Publication Date: 2022-05-11EISAI R&D MANAGEMENT CO LTD
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Patent Information
- Application Number
- MA56466
- Authority / Receiving Office
- MA · MA
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2020-06-29
- Filing Date
- 2020-06-29
- Publication Date
- 2022-05-11
- Estimated Expiration
- 2040-06-29
Abstract
Provided is an anti-EphA4 antibody that can bind to EphA4 and enhance the cleavage of EphA4, as well as a pharmaceutical composition comprising the antibody as the active ingredient.A mouse anti-EphA4 antibody that has binding affinity towards EphA4 and can enhance the cleavage of EphA4 was obtained, and the sequence of the complementarity-determining region (CDR) of the mouse anti-EphA4 antibody was identified. Subsequently, the anti-EphA4 antibody of interest was obtained by producing a humanized antibody of the mouse anti-EphA4 antibody.
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