Substituted quinolineins used as improved inhibitors of NF-κB (NIK)-inducing kinase

MA71481B1Active Publication Date: 2026-06-30NIKAIA PHARMACEUTICALS +4
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Patent Information

Application Number
MA71481
Authority / Receiving Office
MA · MA
Patent Type
Patents
Current Assignee / Owner
Priority Date
2022-10-25
Filing Date
2022-10-25
Publication Date
2026-06-30
Estimated Expiration
2042-10-25
Patent Text Reader

Abstract

<pre>The present invention relates to novel compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds of formula (I) can act as NF-κB (NIK)-inducing kinase inhibitors and, in particular, can induce the intracellular degradation of NIK, making these compounds highly advantageous for use in therapy, including for the treatment or prevention of cancer, inflammatory diseases, and autoimmune diseases.< / pre>
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Citation Information

Patent Citations

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    WO2018007648A1

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    WO2019008011A1

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