cAMP RECEPTOR PROTEIN VARIANT AND PROCEDURE FOR PRODUCING L-AMINO ACID USING THE SAME

MX434193BActive Publication Date: 2026-05-19CJ CHEILJEDANG CORP
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Patent Information

Application Number
MX2021004610
Authority / Receiving Office
MX · MX
Patent Type
Patents
Current Assignee / Owner
Priority Date
2018-11-29
Filing Date
2021-04-21
Publication Date
2026-05-19
Estimated Expiration
2039-07-25

AI Technical Summary

Technical Problem

Existing methods for producing L-amino acids in microorganisms do not effectively leverage the regulatory capabilities of cAMP receptor protein (CRP) mutations to enhance productivity, leading to suboptimal yields and increased production costs.

Method used

Development of a cAMP receptor protein variant with specific amino acid substitutions, particularly at position 196, which is introduced into microorganisms to enhance L-amino acid production, using a vector and polynucleotide encoding this variant.

Benefits of technology

The variant CRP increases the yield of L-amino acids, such as L-threonine and L-tryptophan, reducing production costs and improving efficiency in microbial fermentation processes.

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Abstract

A cAMP receptor protein variant, a microorganism containing the same, and a procedure for producing an L-amino acid using the same are provided.
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