CHARACTERISTICS FOR ANGIOGRAPHY SYRINGE

Abstract

A syringe including a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a tapered distal end wall and a liquid nozzle at a distal end of the tapered distal end wall; a cylindrical load-bearing wall extending axially from the cylindrical side wall beyond a proximal end of the tapered distal end wall; and a plurality of radial ribs positioned around a periphery of the tapered distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the liquid nozzle over at least a portion of the tapered distal end wall.

Description

This application claims the benefit of U.S. Provisional Patent Application No. 62 / 706,340, filed on August 11, 2020, and U.S. Provisional Patent Application No. 63 / 073,519, filed on September 2, 2020, the descriptions of which are incorporated by reference in their entirety. BACKGROUND Field of Technology This description refers generally to the characteristics associated with an angiography syringe. These characteristics provide resistance at the distal end, help prevent fluid leakage from the tip, improve ease of use, and enhance visualization procedures. Background. Syringe injection systems have been among the medical devices used in medical imaging procedures for many years. Many such syringes are manually operated by advancing a plunger extension in operative connection with an internal plunger to pressurize the fluid within the syringe. However, in numerous medical injection procedures, precise control and / or high pressures may be required that cannot be achieved by manually operating the syringe. Therefore, a number of motorized syringes and injectors have been developed for use with such procedures, including medical procedures such as angiography (CV), computed tomography (CT), and magnetic resonance imaging (MRI). For example, U.S. Patent No. 5,383.858 describes a front-loading syringe and a motorized injector, in both pressure-jacketed and non-jacketed configurations, the description of which is incorporated herein for reference. In certain liquid injectors, such as high-pressure liquid injectors that include pressure sleeves to surround the syringe body and prevent syringe expansion and / or failure under high injection pressures, mounting the syringe to the liquid injector may involve several steps to properly align the syringe with the liquid injector and the pressure sleeve. For example, some pressure sleeves cover large portions of the syringe's distal end to prevent distal end failure under high injection pressures. This can complicate loading the syringe into the pressure sleeve and subsequently coupling it with the liquid injector.Similarly, the presence of the pressure sleeve around the cylinder and distal end of the syringe can make it difficult to visualize the syringe and its contents, for example, to ensure that a liquid has been loaded into the syringe and that there are no air bubbles present in the liquid. Once the syringe is attached to the fluid injector, to load the syringes with contrast medium or saline solution, the user typically connects a filling tube or nozzle to the syringe's front nozzle or discharge port and places the other end of the tube / nozzle in fluid communication with a bottle or bag of contrast medium, saline solution, or other fluid. The syringe plunger is retracted (usually by means of an injector piston) to draw the fluid into the syringe until the desired amount is loaded. After filling the syringe, the filling tube is removed from the syringe tip. Often, small amounts of contrast medium or other fluid, such as saline solution, contained in the filling tube may drip from it onto the floor or the injector.Fluid leaks can also occur in multi-patient settings, where a first batch of syringes and tubing may be used for multiple injection procedures, and a second batch may be discarded after a single use and replaced with a new single-use batch before a subsequent injection procedure. Such fluid leaks can contaminate and soil various components of the injector, drip onto the floor in a way that creates a hazard for the technician and patient, and / or contaminate various surfaces within the fluid injection set, and should be minimized and avoided. After filling the syringe with fluid, a connector or priming tube is attached to the syringe's discharge port, and the syringe and connector are primed (typically by advancing the plunger in the syringe) to expel air from the syringe and connector (i.e., to prevent air from being injected into the patient). While this technique can be effective in purging air from the tubing connected to the syringe, dispensing fluids from the end of the tubing is undesirable. Fluids dispensed from the end of the tubing frequently soil the outer surface of the tubing, syringe, and / or injector, drip or leak from the various connections, and fall to the floor. When dealing with contrast media, this is particularly undesirable, as the media is very sticky and tends to migrate onto any surface the operator touches after priming the tubing. Additionally, in some applications, a direct vent tip is attached to the top of a syringe. The vent tip is used to pierce a bottle of contrast medium or saline solution for administration to the patient. In such applications, when the bottle and tip are removed from the syringe, the fluid remaining in the tip may drip onto the syringe tip. Syringes are desired for use in contrast-enhanced imaging procedures, which easily attach to the injector, allow easy visualization and characterization of the syringe's fill status, reduce the effects of contrast contamination and fluid dripping, and have improved characteristics. SYNTHESIS The present description provides a syringe suitable for use in motorized liquid injections, in contrast-enhanced imaging procedures such as computed tomography (CT), angiography (CV), and magnetic resonance imaging (MRI), which includes features that reduce the impact of liquid droplets and also includes other features that improve the capabilities of the syringe, as described in this document. According to one exemplary and non-limiting embodiment, a syringe may include a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a liquid nozzle at a distal end of the conical distal end wall; a cylindrical load-bearing wall extending axially from the cylindrical side wall beyond a proximal end of the conical distal end wall; and a plurality of radial ribs positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the liquid nozzle over at least a portion of the conical distal end wall. According to one exemplary and non-limiting embodiment, the plurality of radial ribs may define a plurality of fluid retention channels between each pair of adjacent radial ribs, wherein the plurality of fluid retention channels is configured to retain a volume of fluid by capillary adhesion when the syringe is rotated from a first upward-facing position to a second downward-facing position. The plurality of fluid retention channels may be configured to retain a volume of fluid ranging from 0.1 to 0.8 milliliters.The volume of fluid contained within the plurality of fluid-retaining channels can be determined, at least partially, from the distance between each adjacent pair of the plurality of radial ribs, the height of each adjacent pair of the plurality of radial ribs, and the distance each pair of radial ribs extends radially inward from the conical distal end wall. The plurality of radial ribs may increase the load-bearing capacity of the conical distal end wall. The plurality of radial ribs may also increase the load-bearing capacity of the cylindrical load-bearing wall. At least one of the plurality of radial ribs may extend a different radial distance inward from the cylindrical load-bearing wall onto the conical distal end wall compared to the remaining radial ribs of the plurality.The cylindrical load-bearing wall can be configured to do so. ML / a / zuzj / uu 1 stop with a retaining surface of a retaining arm of a liquid injector, for retaining the syringe within a pressure sleeve during a pressurized injection procedure. The cylindrical load-bearing wall may extend axially from the cylindrical side wall of the syringe at an angle of 1 degree to 30 degrees with respect to a longitudinal axis of the syringe. A distal surface of the cylindrical load-bearing wall may be radially inclined from a nearer inner portion to a more distal outer portion with respect to the longitudinal axis of the syringe. The angle of the distal surface of the cylindrical load-bearing wall may be configured to prevent the entry of liquid between the cylindrical side wall of the syringe and a pressure sleeve in which the syringe is placed.The angle of the distal surface of the cylindrical load-bearing wall can be configured to increase a radially inward force on the retaining arm of the liquid injector. At least one of the cylindrical load-bearing wall and the plurality of radial ribs can enhance a halo refraction effect on a distal portion of the tapered distal end wall of electromagnetic radiation emitted from at least one electromagnetic radiation source in a piston or plunger head of a liquid injector. A neck can be associated with the liquid nozzle at the distal end of the syringe, wherein the neck includes a liquid passage having a plurality of liquid-diverting ribs extending radially inward at least partially into the liquid passage from an internal surface of the neck.The plurality of fluid diversion ribs can be configured to divert fluid flowing through the neck into the syringe, so that the fluid flows along an inner surface of the tapered distal end wall and the cylindrical side wall of the syringe. The plurality of fluid diversion ribs can be configured to minimize the amount of air bubbles in the fluid within the syringe. The amount of air bubbles in the fluid within the syringe can be minimized by the fluid flowing along the inner surface of the distal end wall and the cylindrical side wall of the syringe. At least a portion of the plurality of fluid diversion ribs can have different profiles. At least a portion of the plurality of fluid diversion ribs can extend from the inner surface to different distances into the fluid passage.The plurality of radial ribs can extend along the conical distal end wall at an angle to a longitudinal axis of the syringe, such that the distance between each adjacent pair of the plurality of radial ribs narrows from the cylindrical load-bearing wall to the liquid nozzle. According to an exemplary and non-limiting embodiment, a syringe may include a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a liquid nozzle at a distal end of the conical distal end wall; a plurality of liquid deflection ribs extending inward from an internal surface of the liquid nozzle; and a plurality of radial ribs positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the liquid nozzle over at least a portion of the conical distal end wall. According to one exemplary, non-limiting embodiment, a cylindrical load-bearing wall may extend axially from the cylindrical side wall beyond a proximal end of the conical distal end wall. The plurality of radial ribs may define a plurality of fluid retention channels between each pair of adjacent radial ribs, wherein the plurality of fluid retention channels is configured to retain a volume of fluid by capillary adhesion when the syringe is rotated from a first upward-facing position to a second downward-facing position. The plurality of fluid retention channels may be configured to retain a volume of fluid ranging from 0.1 to 0.8 milliliters.The volume of fluid contained by the plurality of fluid retention channels can be determined, at least partially, from the distance between each adjacent pair of the plurality of radial ribs, the height of each adjacent pair of the plurality of radial ribs, and the distance that each pair of radial ribs extends distally radially inward from the tapered distal end wall. According to one exemplary and non-limiting embodiment, a syringe may include a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a liquid nozzle at a distal end of the conical wall of the distal end; and a plurality of liquid-diverting ribs extending inwardly from an inner surface of the liquid nozzle, wherein the plurality of liquid-diverting ribs enhance a halo effect of refraction in a distal portion of the conical distal end wall, of electromagnetic radiation emitted by at least one electromagnetic radiation source in a piston or plunger head of a liquid injector. According to one exemplary, non-limiting embodiment, a cylindrical load-bearing wall may extend axially from the cylindrical side wall beyond a proximal end of the conical distal end wall. A plurality of radial ribs may be positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the fluid nozzle over at least a portion of the conical distal end wall. The plurality of radial ribs may MA / a / ZUZJ / UUl l define a plurality of fluid retention channels between each pair of adjacent radial ribs, wherein the plurality of fluid retention channels is configured to retain a volume of fluid by capillary adhesion when the syringe is rotated from a first upward-facing position to a second downward-facing position. The plurality of fluid retention channels can be configured to retain a volume of fluid ranging from 0.1 to 0.8 milliliters. The volume of fluid contained by the plurality of fluid retention channels can be determined, at least partially, from the distance between each adjacent pair of the plurality of radial ribs, the height of each adjacent pair of the plurality of radial ribs, and the distance that each pair of radial ribs extends distally inward from the tapered distal end wall. In one aspect, a syringe with improved features is provided in accordance with the following clauses. Clause 1: A syringe comprising: a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a liquid nozzle at a distal end of the conical distal end wall; a cylindrical load-bearing wall extending axially from the cylindrical side wall beyond a proximal end of the conical distal end wall; and a plurality of radial ribs positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the liquid nozzle over at least a portion of the conical distal end wall. Clause 2: The syringe of Clause 1, wherein the plurality of radial ribs defines a plurality of fluid retention channels between each pair of adjacent radial ribs, wherein the plurality of fluid retention channels is configured to retain a volume of fluid by capillary adhesion when the syringe is rotated from a first upward-facing position to a second downward-facing position. Clause 3: The syringe of Clause 2, wherein the plurality of fluid retention channels are configured to retain a volume of fluid ranging from 0.1 to 0.8 milliliters. Clause 4: The syringe of Clause 2, wherein the volume of fluid contained by the plurality of fluid-retaining channels is determined at least partially from a distance between each adjacent pair of the plurality of radial ribs, a height of each adjacent pair of the plurality of radial ribs, and a distance that each pair of radial ribs extends distally radially inward from the wall of MA / a / ZUZJ / UU 1 conical distal end. Clause 5: The syringe of any of Clauses 1 to 4, wherein the plurality of radial ribs increases the load-bearing resistance of the tapered distal end wall. Clause 6: The syringe of any of Clauses 1 to 5, wherein the plurality of radial ribs increases the load-bearing resistance of the cylindrical load-bearing wall. Clause 7: The syringe of any of Clauses 1 to 6, wherein at least one of the plurality of radial ribs extends a different radial distance inward from the cylindrical load-bearing wall over the conical distal end wall, compared to the remaining radial ribs of the plurality of radial ribs. Clause 8: The syringe of any of Clauses 1 to 7, wherein the cylindrical load-bearing wall is configured to abut a retaining surface of a retaining arm of a liquid injector to retain the syringe within a pressure sleeve during a pressurized injection procedure. Clause 9: The syringe of any of Clauses 1 to 8, wherein the cylindrical load-bearing wall extends axially from the cylindrical side wall of the syringe at an angle of 1 degree to 30 degrees with respect to a longitudinal axis of the syringe. Clause 10: The syringe of any of Clauses 1 to 9, wherein a distal surface of the cylindrical load-bearing wall is radially inclined from a more proximal inner portion to a more distal outer portion with respect to the longitudinal axis of the syringe. Clause 11: The syringe of Clause 10, wherein the angle of the distal surface of the cylindrical load-bearing wall is configured to prevent the entry of fluid between the cylindrical side wall of the syringe and a pressure sleeve in which the syringe is placed. Clause 12: The syringe of Clause 10 or Clause 11, wherein the angle of the distal surface of the cylindrical load-bearing wall is configured to increase a radially inward force on the retaining arm of the liquid injector. Clause 13: The syringe of any of Clauses 1 to 12, wherein at least one of the cylindrical load-bearing wall and the plurality of radial ribs enhances a halo refraction effect in a distal portion of the tapered distal end wall of electromagnetic radiation emitted from at least one source of electromagnetic radiation in a piston or plunger head of a liquid injector. Clause 14: The syringe of any of Clauses 1 to 13, further comprising a neck associated with the liquid nozzle at the distal end of the syringe, wherein the neck includes a liquid passage having a plurality of liquid deflecting ribs extending radially inward at least partially into the liquid passage from an internal surface of the neck. Clause 15: The syringe of Clause 14, wherein the plurality of liquid diversion ribs are configured to divert a liquid flowing through the neck into the syringe, so that the liquid flows along an inner surface of the conical distal end wall and the cylindrical side wall of the syringe. Clause 16: The syringe of Clause 14 or Clause 15, wherein the plurality of liquid diversion ribs are configured to minimize the amount of air bubbles in the liquid in the syringe. Clause 17: The syringe of Clause 16, wherein the amount of air bubbles in the liquid in the syringe is minimized by the liquid flowing along the inner surface of the distal end wall and the cylindrical side wall of the syringe. Clause 18: The syringe of any of Clauses 14 to 17, wherein at least a portion of the plurality of liquid-diverting ribs have different profiles. Clause 19: The syringe of any of Clauses 14 to 18, wherein at least a portion of the plurality of liquid-diverting ribs extend from the inner surface at different distances into the liquid passage. Clause 20: The syringe of any of Clauses 1 to 19, wherein the plurality of radial ribs extend along the tapered distal end wall at an angle to a longitudinal axis of the syringe, such that the distance between each adjacent pair of the plurality of radial ribs narrows from the cylindrical load-bearing wall to the liquid nozzle. Clause 21: A syringe comprising: a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a liquid nozzle at a distal end of the conical distal end wall; a plurality of liquid-diverting ribs extending inward from an internal surface of the liquid nozzle; and a plurality of radial ribs positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the liquid nozzle over at least a portion of the conical distal end wall. Clause 22: The syringe of Clause 21, further comprising a cylindrical load-bearing wall extending axially from the cylindrical side wall beyond a proximal end of the conical distal end wall. Clause 23: The syringe of Clause 21 or Clause 22, wherein the plurality of radial ribs defines a plurality of fluid retention channels between each pair of adjacent radial ribs, wherein the plurality of fluid retention channels is configured to retain a volume of fluid by capillary adhesion when the syringe is rotated from a first upward-facing position to a second downward-facing position. Clause 24: The syringe of Clause 23, wherein the plurality of fluid retention channels are configured to retain a volume of fluid ranging from 0.1 to 0.8 milliliters. Clause 25: The syringe of Clause 23, wherein a volume of fluid containing the plurality of fluid retention channels is determined at least partially from a distance between each adjacent pair of the plurality of radial ribs, a height of each adjacent pair of the plurality of radial ribs, and a distance that each pair of radial ribs extends distally radially inward from the tapered distal end wall. Clause 26: A syringe comprising: a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a liquid nozzle at a distal end of the conical distal end wall; and a plurality of liquid-diverting ribs extending inwardly from an inner surface of the liquid nozzle, wherein the plurality of liquid-diverting ribs enhance a refraction halo effect in a distal portion of the conical distal end wall, of electromagnetic radiation emitted from at least one electromagnetic radiation source in a piston or plunger head of a liquid injector. Clause 27: The syringe of Clause 26, further comprising a cylindrical load-bearing wall extending axially from the cylindrical side wall beyond a proximal end of the conical distal end wall. Clause 28: The syringe of Clause 26 or Clause 27, further comprising a plurality of radial ribs positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the liquid nozzle over at least a portion of the conical distal end wall. Clause 29: The syringe of Clause 28, wherein the plurality of radial ribs defines a plurality of fluid retention channels between each pair of adjacent radial ribs, wherein the plurality of fluid retention channels is configured to retain a volume of fluid by capillary adhesion when the syringe is rotated from a first upward-facing position to a second downward-facing position. Clause 30: The syringe of Clause 29, wherein the plurality of fluid retention channels are configured to retain a volume of fluid ranging from 0.1 to 0.8 milliliters. Clause 31: The syringe of Clause 29, wherein a volume of the fluid containing the plurality of fluid retention channels is determined at least partially from a distance between each adjacent pair of the plurality of radial ribs, a height of each adjacent pair of the plurality of radial ribs, and a distance that each pair of radial ribs extends distally radially inward from the tapered distal end wall. The foregoing is a summary and, therefore, may contain simplifications, generalizations, inclusions, and / or omissions of details. Consequently, those skilled in the art will appreciate that the summary is for illustrative purposes only and is not intended to be limiting in any way. Other aspects, features, and advantages of the devices, processes, and / or other subject matter described herein will become apparent in the teachings set forth in this application. In addition to the illustrative aspects and features described above, other aspects and features will be made clear with reference to the drawings and the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS The novel features described herein are set forth in detail in the appended claims. However, these features, both in terms of organization and methods of operation, may be better understood with reference to the following description, taken in conjunction with the accompanying drawings. FIG. 1 is a perspective view of a syringe according to an example in the present description. FIG. 2 is a side view of the syringe in FIG. 1. FIG. 3 is a cross-sectional view of the syringe in FIG. 1 along line AA. FIG. 4 is a top view of the syringe in FIG. 1. FIG. 5 is a perspective view of a syringe according to another example in this disclosure. FIG. 6 is a perspective view of a syringe according to another example in this disclosure. FIG. 7A is a cross-sectional view of a syringe held in a retention arrangement according to an example in the present description. FIG. 7B is a cross-sectional view of the syringe in FIG. 7A being inserted into the retention arrangement. FIG. 8 is a side view of a syringe according to an example in this disclosure. FIG. 9 is a close-up side view of the distal tip of the syringe in FIG. ML / a / zuzj / uu 1 8. DETAILED DESCRIPTION The following detailed description refers to the accompanying drawings, which form an integral part thereof. The illustrative features shown and described in the detailed description, the drawings, and the claims are not intended to be limiting. Other features may be used, and other changes may be made, without departing from the scope of the subject matter presented herein.Before explaining in detail the various aspects of the syringe assembly and its features, it should be noted that the aspects described in this document are not limited in their application or use to the construction details and arrangement of the parts illustrated in the accompanying drawings and description. Instead, the described devices can be positioned or incorporated into other devices, variations, and modifications thereof, and can be implemented or carried out in various ways. Consequently, the aspects and features of the syringe described in this document are illustrative in nature and are not intended to limit its scope or application.Furthermore, unless otherwise stated, the terms and expressions used in this document have been chosen to describe the various aspects and characteristics of the syringe for the reader's convenience and do not limit its scope. It should also be understood that any one or more of the syringe components and characteristics, their expressions, and / or their examples may be combined with any one or more of the other components, their expressions, and / or examples without limitation. Furthermore, in the following description, terms such as frontal, posterior, internal, external, superior, inferior, and the like should be understood as words of convenience and should not be interpreted as limiting terms. As used here, the term proximal, when used to describe a portion of a syringe, generally refers to the portion of the syringe closest to the injector, and the term distal, when used to describe a portion of a syringe, generally refers to the portion of the syringe closest to the patient (i.e., the end of the syringe nozzle). The terminology used herein is not intended to be limiting to the extent that the devices described herein, or portions thereof, may be coupled or used in other orientations. The various aspects and features of the syringe will be described in more detail with reference to the drawings. This description relates to a syringe design for use with a motorized fluid injector used in medical imaging procedures. According to various embodiments, certain medical imaging procedures may involve the injection of a contrast medium or agent that highlights certain features in the medical image. Known as contrast-enhanced medical imaging, the process generally involves injecting a contrast medium with a suitable flushing agent, such as saline solution, before or during the imaging procedure. Motorized fluid injectors have been used to control the injection of fluids and are typically designed with one or more syringes to contain and dispense the contrast medium, flushing fluid, and other medical fluids administered before or during the imaging procedure. For example, U.S. Patents Nos. 5,383,858; 6,652,489; 7,563,249; 8,945.051; 9.173.995; and 10.507.319 describe front-loading syringes and motorized injectors in both sleeved and unsleeved examples; the description is incorporated by this reference. Common contrast-enhanced medical imaging procedures include computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET, SPECT), and angiography (CV). Due to the viscosity and the need to deliver contrast volumes over a short period of time through small-diameter tubing and / or catheter assemblies to provide a tight bolus, certain injection procedures may be performed at high injection pressures, such as pressures up to 2.068 MPa (300 psi) for CT and MRI, and pressures up to 8.27 MPa (1200 psi) for CV procedures.The injector can be configured to inject or dispense the liquid medium contained in the first, second and / or additional syringes in a controlled manner, as can be used in medical procedures such as angiography, CT, PET and MRI. During the injection process, many potential issues can arise that should be avoided, such as slow or difficult loading of the syringe into the pressure sleeve, syringe deformation or failure, or detachment of the syringe from the fluid injector due to high injection pressures, leakage of contrast or saline solution that can contaminate one or more surfaces of the syringe or injector components, air entering the syringe and potentially injecting air into the patient, slow filling rates with bubble formation, and the inability to see the syringe contents, among other problems. The syringe and the features described herein mitigate or prevent one or more of these issues. According to a first embodiment, the present description provides a syringe 2 that may include a proximal end 4, a distal end 6, and a cylindrical sidewall 8 extending between the proximal end 4 and the distal end 6. The distal end 6 may include a liquid nozzle 10 at the distal end 12 of a tapered distal end wall 14, as shown in Figures 1-3. In various embodiments of the present disclosure, the syringe 2 may include a tube or nozzle clamp embodiment 16 as described in PCT International Application No. PCT / US2021 / 018523, which disclosure is incorporated in full by this reference. In other embodiments, the syringe may include a Luer-type connector (not shown) or other connecting mechanism for attaching the syringe to a tube and / or nozzle assembly. According to certain embodiments, the syringe 2 may include a cylindrical load-bearing wall 18 extending distally from the cylindrical side wall 8 beyond a proximal end 20 of the tapered distal wall 14. The cylindrical load-bearing wall 18 may protrude along a longitudinal axis L and provides a distal surface 22 configured to abut an internal proximal surface 100 of one or more retaining elements 102 at a distal end of one or more retaining arms 103 (see FIGS. 7A and 7B) to retain the syringe 2 within the pressure sleeve, keep the syringe 2 coupled with the fluid injector, and support a load associated with a pressurized fluid supply (e.g., a load produced by a fluid injector motor when it pressurizes the fluid using a motorized piston).For example, in a CT injection protocol, the cylindrical load-bearing wall 18 can be configured to withstand a load of at least 2.068 MPa (300 psi). According to other embodiments during a CV injection protocol, the cylindrical load-bearing wall 18 can be configured to withstand a load associated with the high pressures of an angiography injection. For example, in certain angiography injections, the fluid within syringe 2 can be pressurized to up to 8.27 MPa (1200 psi). High pressures may be necessary to deliver the viscous contrast agent or the less viscous saline solution through a small-diameter catheter typically associated with a CV injection procedure.As the cylindrical load-bearing wall 18 rests against the inner wall of the distal end of the pressure sleeve, the load from the syringe 2 is transferred to one or more retaining elements 102 at the distal end of one or more retaining arms 103, and ultimately to frame features of the liquid injector. The cylindrical load-bearing wall 18 may be continuous or discontinuous around the circumference of the distal end 6 of the syringe 2. In certain embodiments, the cylindrical load-bearing wall 18 is continuous around the circumference of the distal end 6 of the syringe 2. In certain embodiments, as shown in FIGS. 2 and 3, the cylindrical load-bearing wall 18 extends and widens from the cylindrical side wall 8 towards the distal end, such that the distal outer diameter of the load-bearing wall 18 is greater than the outer diameter of the cylindrical side wall 8. According to certain embodiments, the cylindrical load-bearing wall 18 can be widened at an angle of 1 to 30° with respect to the longitudinal axis L of the syringe 2. The widened cylindrical load-bearing wall 18 allows for the easy installation of the syringe 2 in the pressure sleeve 104 and the coupling of the syringe 2 and the corresponding plunger with the liquid injector piston. To clarify, the flared surface 19 extends from the outer surface of the cylindrical side wall 8 to the distal surface 22 of the load-bearing wall 18. For example, as illustrated in FIGURES 7A and 7B, as the syringe is lowered into the pressure sleeve past the one or more retaining elements 102, the flared cylindrical load-bearing wall 18 can push the one or more retaining elements 102 and the corresponding retaining arms 103 outward. A user may need to apply a certain amount of downward force (for example, the liquid injector assembly and pressure sleeve may be in a vertical position with the open end of the pressure sleeves pointing vertically upward) to allow the downward force to move the one or more retaining elements 102 outward against a load-restoring force.Once the distal end of the cylindrical load-bearing wall 18 is pushed beyond the inner proximal surface 100 of one or more retaining elements 102, the load-restoring force can push the retaining elements 102 back to an initial position where the inner proximal surface 100 of one or more retaining elements 102 abuts the distal angled surface of the cylindrical load-bearing wall 18 when the syringe 2 and plunger are placed under load by the liquid injector piston. In this way, a technician can install the syringe 2 in the injector simply by applying downward force to the syringe 2 until it clicks into the pressure sleeve assembly. In certain embodiments, an audible indication, such as a click or a snap, can be heard when the retaining elements close to indicate that the syringe has been properly installed.The snap-lock mechanism can also provide a visual indication to the technician that the syringe is correctly installed. Removal of syringe 2 can be facilitated by the outward movement of one or more retaining elements 102 and the corresponding retaining arms 103, either manually by the technician or by an injector motor. Suitable embodiments of the retaining arm mechanism are described in PCT International Application No. PCT / US2020 / 049885, a description of which is incorporated herein by reference. In various embodiments, the outer diameter of the flared cylindrical load-bearing wall 18 can be closely supported against the side wall of the pressure sleeve 104 and / or the one or more retaining elements 102, substantially preventing the entry of any spilled medical fluid, such as contrast medium or saline solution, between the cylindrical side wall 8 of the syringe 2 and the pressure sleeve 104 (see FIG. 7A). In certain embodiments, the pressurization of the syringe 2 and the associated compliance due to the expansion of the side wall 8 and the distal end wall 14 of the syringe 2 under pressurization can further seal the cylindrical side wall 8 of the syringe 2 against the pressure sleeve 104 and / or the one or more retaining elements 102, thereby further enhancing the sealing nature of the interaction.According to various embodiments, a coating or elastomeric material can be placed on the inner proximal surface 100 of one or more retention elements 102 and / or on the distal surface 22 of the cylindrical load-bearing wall 18, to form a liquid-tight seal between them when the syringe rests closely on one or more retention elements 102. With reference to FIGS. 1 to 4, the distal end 6 of the syringe 2 may further include a plurality of radial ribs 24 positioned around a periphery of the conical distal end wall 14. The plurality of radial ribs 24 extend inward from an inner edge of the cylindrical load-bearing wall 18 over at least a portion of the conical distal end wall 14 toward the liquid nozzle 10. In certain embodiments, the radial ribs 24 may be provided at different lengths along the cylindrical load-bearing wall 18. In other embodiments, the plurality of radial ribs may extend only a short distance along the conical distal end wall 14, for example, less than 1.5 cm.In the case of using shorter radial ribs 24, it may be easier for a user to identify one or more air bubbles in the syringe 2, since the radial ribs 24 do not significantly obstruct the user's view into the syringe 2, for example, when the liquid injector is in the upright vertical position and the natural buoyancy of the one or more air bubbles causes them to rise toward the distal end of the tapered end wall 14. According to various embodiments, the plurality of radial ribs 24 define a plurality of liquid retention channels 26 between them. Each liquid retention channel 26 can be located between each pair of adjacent radial ribs 24. The plurality of liquid retention channels 26 can be configured to retain a volume of liquid that has previously dripped from the liquid nozzle 10.For example, the fluid in the fluid retention channels 26 will be retained within the fluid retention channels 26 when the syringe 2 is rotated from a first vertically upward-facing position to a second downward-facing, inclined position. Capillary adhesion (also known as capillary action) and the surface tension of the fluid allow the fluid volume to be retained in the plurality of fluid retention channels 26 against the force of gravity. In addition, the plurality of radial ribs 24 can abut against the inner wall of the cylindrical load-bearing wall 18 to further retain the fluid.For example, in certain embodiments, syringe 2 can be filled with a liquid, such as a contrast agent, saline solution, or other medical fluid, with the injector head and distal end 6 of one or more syringes 2 held upright, for example, to facilitate filling the liquid through a nozzle and / or to monitor and visualize the amount of air entering syringe 2 during a filling process. In certain embodiments, during filling through a nozzle or fluid line, switching between the filling and delivery fluid lines, or purging air, a small amount of fluid may leak or drip from the fluid nozzle 10 of syringe 2, such as when the nozzle or fluid line is removed after filling or purging. During many conventional fluid injection procedures, after filling in the vertical configuration, an injector head may be rotated so that the distal ends 6 of one or more syringes 2 are angled downwards. This ensures buoyancy causes any airflow that may remain in syringe 2 to rise to the proximal end 4 of syringe 2, thereby reducing the possibility of air injection and embolism. With conventional syringe designs, the volume of fluid that drips may flow down an external surface of the syringe, soiling or contaminating various surfaces of the fluid injector. In specific examples, small volumes of fluid may drip from the syringe onto the floor, creating a hazard for the technician and the patient, and / or contaminating various surfaces within the fluid injection assembly.In addition, since many contrast agents are sticky and viscous solutions, this can cause a sticky film to build up on the floor and other surfaces, which can create a safety hazard and may further increase unnecessary contact with the contrast or other medical fluid and require additional cleaning operations. According to various embodiments, the plurality of liquid retention channels 26 can be configured to retain the volume of liquid that has dripped from the liquid nozzle 10, for example, by adhesion or capillary action between adjacent radial ribs 24. As illustrated in Fig. 4, the width of the space between adjacent radial ribs 24 can be designated d1, d2, d3, where, in some respects, the width of the space is constant, so that d1=d2=d3, and in other respects, the width of the space is variable, so that d1 ≤ d2 ≤ d3. With respect to these latter aspects, d1 < d2 < d3, or d1 > d2 > d3, or the appropriate space width can be determined in some other way, without limitation. In various embodiments, since the adjacent radial ribs 24 are arranged radially, the width of the space can be increased with the radial distance from the central longitudinal axis L of the syringe 2.Alternatively, the width of the space can remain constant by increasing the width of the radial ribs 24 with a radial distance from the central axis. According to various embodiments, the distance between two adjacent radial ribs 24 that define the space associated with the fluid retention channels 26 (i.e., d) can vary from 0.0254 cm to 0.635 cm (0.01 to 0.25 in). Further details on capillary action are described in International PCT Publication No. WO 2017 / 091636, a description of which is incorporated herein by reference. According to certain embodiments, the plurality of liquid retention channels 26 can retain a maximum total volume of liquid ranging from 0.1 ml to 0.8 ml when the syringe 2 is rotated from a first upward-facing position to a second downward-facing position at an angle. Other embodiments can adjust the maximum total volume of liquid by changing the heights of the plurality of radial ribs and / or changing the distance between adjacent radial ribs.In particular embodiments, the capillary volume of fluid that can be contained by adjacent radial ribs 24 is determined at least partially from the distance between each adjacent pair of the plurality of radial ribs 24, the height of each adjacent pair of the plurality of radial ribs 24, and a distance that each adjacent pair of radial ribs 24 extends distally inwardly along the conical distal end wall 14. That is, the fluid volume can be determined by one or more of the distance between adjacent pairs of radial ribs 24, the depth of the fluid retention channels 26 between adjacent pairs of radial ribs 24, and the length of adjacent pairs of radial ribs 24 and the related length of the fluid retention channels 26. In certain embodiments, at least a portion of the plurality of radial ribs 24 extends at different distances from the cylindrical load-bearing wall 18 onto the conical distal end wall 14. For example, in FIG. 4, the plurality of radial ribs 24 may extend from the cylindrical load-bearing wall 18 onto a portion of the conical distal end wall 14 of syringe 2. In other embodiments, as illustrated in FIG. 5, the plurality of radial ribs 24 may extend from the cylindrical load-bearing wall 18 to the conical distal end wall 14 of syringe 2 toward the liquid nozzle 10 of syringe 2. As illustrated in FIG. 5, the plurality of radial ribs 24 can extend at different distances from the cylindrical load-bearing wall 18, and some of the radial ribs 24 can have different heights compared to other radial ribs 24 (see FIG. 5). As can be seen in the illustrations, in various embodiments, the plurality of radial ribs 24 abut the cylindrical load-bearing wall 18 of the syringe 2, thereby forming a reservoir at the distal end 6 of the syringe 2 that helps direct the medical fluid into the fluid-retaining channels 26, and also provides additional volume for retaining the fluid in the reservoir that has the cylindrical load-bearing wall 18 as a fluid-retaining wall. In other embodiments, as shown in FIG. 6, the plurality of ribs 24 may be circumferential and arranged concentrically around the conical distal end wall 14. The concentric circumferential ribs 28 may be arranged from the cylindrical load-bearing wall 18 towards the liquid nozzle 10 of the syringe 2. In various embodiments, including the syringes 2 illustrated in FIGS. 1 to 6, the plurality of radial ribs 24 and / or the plurality of circumferential ribs 28 can increase the load-bearing strength of the tapered distal end wall 14. For example, the plurality of radial ribs 24 or circumferential ribs 28 can provide increased thickness to the tapered distal end wall 14 where the radial ribs 24 or circumferential ribs 28 are located, thereby reinforcing the strength of the tapered distal end wall 14. In various embodiments, the increased wall strength can help support and limit compliance expansion of the tapered distal end wall 14 during a pressurized fluid injection procedure.According to various embodiments, the increased thickness of the tapered distal end wall 14 where the radial ribs 24 or circumferential ribs 28 are located can reduce the need to reinforce the pressure sleeve of the tapered distal end wall 14. For example, as illustrated in FIG. 7A, the pressure sleeve 104 can be substantially cylindrical, supported by the retaining elements of the syringe 102, and the tapered distal end wall 14 of syringe 2 can withstand high injection pressures (up to 8.27 MPa (1200 psi)) without any reinforcement of the pressure sleeve 104 and / or the retaining elements of syringe 102. This can allow easy visualization of the tapered distal end wall 14 by the user, for example, to check the liquid filling volume and the presence or absence of one or more air bubbles in syringe 2. In certain embodiments, the plurality of radial ribs 24 can increase the load-bearing capacity of the cylindrical load-bearing wall 18. For example, the plurality of radial ribs 24 are supported by and connected to the cylindrical load-bearing wall 18. This can increase the load-bearing capacity of the cylindrical load-bearing wall 18, for example, by increasing the circumferential strength of the wall. The connection between the plurality of radial ribs 24 and the cylindrical load-bearing wall 18 can also increase the load-bearing capacity of the cylindrical load-bearing wall 18 by preventing inward or outward deformation or torsion of the cylindrical load-bearing wall 18 when the pressure load is applied to the syringe 2. As illustrated in FIGS. 3 and 8, according to one embodiment of the present description, the proximal end 4 of the syringe 2 may have a diameter D1 wider than the diameter D2 of the remaining portion of the cylindrical side wall 8. In this example, the working area 7 of the syringe 2 into which a plunger 106 is pushed through the liquid passage of the cylindrical side wall 8 may have a smaller diameter D2 compared to the diameter D1 of the plunger storage area 5 in the proximal end 4. According to this embodiment, the plunger storage area 5 is a region of the syringe where the plunger is positioned during manufacturing and storage, and the wider diameter D1 prevents compression of the outer circumference of the plunger's rubber cover during shipping and storage.This ensures a liquid-tight seal between the side wall of syringe 8 and the rubber plunger cover when the plunger moves from the wider diameter D1 of the storage zone 5 to the narrower diameter D2 of the working zone 7 of syringe 2. In various embodiments of the present description, a liquid injector in which syringe 2 is held can measure a force on a piston motor associated with pushing a plunger 106 through the liquid passage of syringe 2 and, in particular, the additional force required to move the plunger 106 from the wider diameter D1 of the storage zone 5 to the narrower diameter D2 of the working zone 7 of syringe 2. Based on the forces that the liquid injector applies to the piston, the liquid injector can determine the size of syringe 2 being used in the liquid injector.For example, in a longer syringe 2 containing 200 ml of liquid, the piston can push the plunger through the proximal end 4 of syringe 2 from the plunger storage zone 5, which has a diameter D1, to the working zone 7, which has a diameter D2. Because D1 is larger than D2, less force is required to push the piston through the proximal end 4 of syringe 2 than through the working zone 7 of syringe 2. Therefore, the liquid injector can calibrate the piston position for when the plunger 106 is pushed into the working zone 7 of syringe 2 based on the change in force applied to the piston as it moves from the storage zone 5 at the proximal end 4, with diameter D1, to the working zone 7, with diameter D2.For longer, higher-volume syringes that have a larger working zone 7, the change in force applied to the piston will occur at a predetermined piston position corresponding to the proximity of the proximal end 4 of syringe 2 to the injector head, whereas for shorter, lower-volume syringes that have a smaller working zone 7 (e.g., 100 ml or 50 ml) that will be placed more distally in the pressure sleeve (i.e., when the distal end 6 of syringe 2 abuts the syringe retaining element 102), the change in force applied to the piston will occur at a predetermined piston position where the piston extends further along the piston path, corresponding to the fact that the proximal end 4 and plunger of syringe 2 are further from the injector head in the initial position. The position at which the fluid injector registers the change in force applied to the piston due to the plunger's movement from storage zone 5 to working zone 7 allows the injector to determine the length, and therefore the volume, of the syringe that has been loaded into the pressure sleeve, and to make various adjustments to any programmed injection procedure accordingly. Furthermore, if the fluid injector observes that the piston force change does not occur, or observes a deviation from the expected force change, the fluid injector can stop the fluid injection procedure and notify the technician that an error has occurred.For example, if a syringe is inadvertently reused, the plunger will likely not be in the initial storage zone 5, and the force change position will not be where expected. This allows the fluid injector to notify the technician and prevent the inadvertent reuse of a syringe. Similarly, if the plunger has inadvertently moved to the working zone 7, for example, during shipping, the fluid injector will notice the missing force change and avoid using a potentially damaged syringe (for example, where the fluid seal between the plunger and the syringe sidewall may be compromised). In other embodiments, as shown in FIG. 7A, the cylindrical load-bearing wall 18 may have a distal surface 22 configured to interact with and support a proximal surface 100 of the syringe retaining elements 102 of the syringe retaining arms 103 of the liquid injector. According to specific embodiments, the distal surface 22 of the cylindrical load-bearing wall 18 may have a radial angle such that the inner circumferential edge of the distal surface 22 is proximal along the longitudinal axis relative to the outer circumferential edge of the distal surface 22. According to this embodiment, the corresponding proximal surface 100 of the syringe retaining elements 102 is radially inclined in a direction complementary to the radial angle of the distal surface 22 of the cylindrical load-bearing wall 18.According to various embodiments, the angle of the distal surface 22 can vary from 1aa to 89a, and in particular embodiments, from 1aa to 30a, the angle of the corresponding proximal surface 100 being complementary to it. Thus, when the radially angled distal surface 22 of the cylindrical load-bearing wall 18 interacts with the corresponding radially angled proximal surface 100 of the syringe retaining elements 102 when the syringe 2 is under load during a dispensing process, the two surfaces 22 and 100 interact when the pressurized syringe 2 is driven in the distal direction along the longitudinal axis L, so that a retaining force is established on the retaining arms 103 which drives the retaining arms 103 radially inwards to maintain the closed configuration.In this way, the forces retaining syringe 2 within the pressure sleeve 104 and the fluid injector's retention mechanism increase during pressurized fluid delivery during a contrast injection procedure. As a non-limiting example, when syringe 2 is inserted into the fluid injector, the cylindrical load-bearing wall 18 can be configured to move the retaining arms 103 outward, opening them and allowing syringe 2 to move into the fluid injector. After syringe 2 has moved past the syringe's retaining elements 102, the retaining arms 103 can be configured to move inward, closing against each other to retain syringe 2 in the fluid injector. As described in U.S. Patent No. 10,420,902, the description of which is incorporated herein by reference, and as shown in FIGS. 8 and 9, the presence of small amounts of air (up to 5% of the total volume of the syringe) in syringe 2 can be visualized by the presence or absence of an illuminated halo 40a at the tapered distal end 6 of syringe 2. For example, electromagnetic radiation may be reflected and refracted from a colored surface, or may be shown through a translucent or transparent plunger cap (from light sources in the piston head). If syringe 2 is completely filled with a liquid, electromagnetic radiation will be refracted / reflected against the side wall of syringe 8 and the conical distal end wall 14 to show a halo refraction effect in the form of an illuminated halo 40a around the circumference of the distal portion of the conical distal end 6 of syringe 2.In the presence of small amounts of air (e.g., up to 5 mL or more), the illuminated halo 40a is not visible. This provides a method for a technician to visually determine whether air is present in syringe 2 and perform a priming / purge operation to remove the air and prevent air injection into the patient. In certain embodiments, the visualization process can also be performed by the injector when equipped with a suitable camera and associated software. According to various embodiments of the present description, at least one of the load-bearing cylindrical wall 18 and the plurality of radial ribs 24 can increase the amount of refracted electromagnetic radiation at the distal end 6 of syringe 2 when syringe 2 is filled with a liquid.For example, the plurality of radial ribs 24 can act similarly to a Fresnel lens and increase the reflection / refraction of electromagnetic radiation so as to create a brighter illuminated halo around the circumference of the distal portion of the conical distal end 6 of the syringe 2. In other embodiments, electromagnetic radiation can also be reflected from the conical distal end and illuminate a halo 40b around at least a portion of the cylindrical load-bearing wall 18, for example, around the plurality of radial ribs 24. In specific embodiments, electromagnetic radiation can be emitted from at least one electromagnetic radiation source in a piston head of a liquid injector. In other embodiments, electromagnetic radiation can be reflected from at least a portion of a plunger surface 106 of a syringe 2. In certain embodiments, the syringes 2 of the present description may include one or more features that improve the flow of fluid into and out of the MA / a / ZUZJ / UUl l syringe 2 during the filling and liquid delivery processes. According to various embodiments, the syringe 2 may include a neck associated with the liquid nozzle 10 at the distal end 6 of the syringe 2. The neck may include a larger diameter than conventional syringes, for example, to include a connecting element as described in PCT International Application No. PCT / US2021 / 018523. The neck of the syringe 2 may include a liquid passage having a plurality of liquid diversion ribs 30 extending radially inward from an inner surface of the neck at least partially into the liquid passage, as illustrated in FIGS. 3 and 4. According to various embodiments, the plurality of liquid diversion ribs 30 can divert a liquid flowing through the liquid nozzle 10 into the syringe 2 during a filling procedure so that the liquid flows along the internal surfaces of the conical distal end wall 14 and the cylindrical side wall 8 of the syringe 2. In certain embodiments, the plurality of liquid diversion ribs 30 can include ribs that extend radially inward at different distances (compare ribs 30 and 31 in FIG. 4) and / or extend to different lengths along the longitudinal axis L of the liquid nozzle 10.Without intending to be limited by any interpretation, it is believed that the redirection of fluid flow through the fluid nozzle of syringe 10 is the result of a Coanda effect, where the fluid-diverting ribs 30 cause the fluid to adhere to the inner side wall of the conical distal end wall 14 and the cylindrical side wall 8 of syringe 2. For example, capillary adhesion of the fluid against the walls of the fluid-diverting ribs 30 may allow surface tension to hold the fluid against the inner side walls of the neck and continue towards the inner side wall of the conical distal end wall 14 and the cylindrical side wall 8.Directing the fluid downwards along the inner sidewalls of the syringe, rather than allowing it to flow into the syringe without contacting the inner sidewalls, results in fewer air bubbles in the fluid during the filling procedure. Conversely, with conventional syringes lacking fluid-diverting ribs 30, the fluid may flow / drip down the middle of the syringe's fluid nozzle 10 and drip towards the plunger 106, leading to the formation of air bubbles in the fluid. These air bubbles can adhere to the plunger 106 and the sidewall surfaces and are typically difficult to remove during priming. The resulting air bubbles can increase the risk of air embolism from the injection of small amounts of air, particularly during angiography procedures.As noted, particularly with high-pressure CV imaging procedures, air bubbles in the syringe and / or fluid line must be avoided to prevent gas embolism. In accordance with these embodiments, fluid diversion ribs 30 minimize the amount of air bubbles. ML / a / zuzj / uu 1 in the liquid of syringe 2. Previous work had shown that a liquid diverter in the middle of the flow path through the nozzle reduces bubble formation during filling; see, for example, PCT International Publication No. WO 2017 / 0914643, a description of which is incorporated herein by reference. The described liquid-diverting ribs 30 provide a similar effect, without the need for a liquid-diverting feature in the flow path, thus simplifying the manufacture and injection molding of syringe 2. The amount of air bubbles in the liquid of the filled syringe 2 can be minimized by the liquid flowing along the inner surfaces of the distal end wall 14 and the cylindrical side wall 8 of syringe 2, rather than dripping / flowing directly from the liquid nozzle of syringe 10 onto the plunger surface.In one embodiment of the present disclosure, the liquid diversion ribs 30 can also enhance the illuminated circumferential halo effect described herein, to identify whether air bubbles are present in syringe 2. As observed with the plurality of radial ribs 24, the liquid diversion ribs 30 can further enhance and reflect / refract the incident electromagnetic radiation, so as to increase the brightness of the illuminated halo observed around the circumference of the distal portion of the tapered distal end 6 of syringe 2. In specific embodiments, at least a portion of the plurality of liquid diversion ribs 30 can have different cross-sectional profiles.In other embodiments, at least a portion of the plurality of liquid-diverting ribs 30 may extend from the inner surface of the liquid nozzle 10 to different distances into the distal portion of the conical distal end 6 of the syringe 2. According to various embodiments, the plurality of liquid-diverting ribs 30 can also allow for higher filling speeds, potentially due to a more laminar flow of the liquid into syringe 2 as it passes through the liquid-diverting ribs 30. Therefore, the time between procedures can be substantially reduced, as the syringes can be filled more quickly than conventional syringes. Furthermore, the filling rate can be increased because bubble formation during filling is reduced, resulting in smaller priming volumes and less residual liquid production associated with larger priming volumes. According to various embodiments, the features described herein can increase the ease of injection molding of a syringe 2. For example, syringes 2 can be formed from medical-grade plastics, such as PET, polycarbonate, polyethylene, and blends thereof, and can be formed into a syringe shape through an injection molding process. During injection molding, these features can cause problems during mold removal, such as indentation. Furthermore, certain features may require specific and costly mold configurations that can still result in high rejection rates.According to various embodiments of syringe 2 and the features described therein, the configuration of the plurality of radial ribs 24, the liquid diversion ribs 30 and the cylindrical load-bearing wall 18 can eliminate the notches of an injection mold for injection molding syringe 2. This disclosure describes multiple beneficial features for a syringe 2. It is noted that various combinations of the described features may be incorporated into a syringe as required by the intended use of the syringe and the characteristics of the fluid injector. For example, a syringe may include at least one of the features and may include several other features described as needed. For example, according to one embodiment, a syringe may include a plurality of radial ribs 24 around the periphery of the tapered distal end wall 14 and a cylindrical load-bearing wall 22 as described herein, but may not include a plurality of fluid-diverting ribs 30.According to another embodiment, a syringe may include a plurality of radial ribs 24 around the periphery of the tapered distal end wall 14, a cylindrical load-bearing wall 22, and a plurality of fluid-diverting ribs 30 as described herein. According to another embodiment, a syringe may include a cylindrical load-bearing wall 22 and a plurality of fluid-diverting ribs 30, but not the plurality of radial ribs 24 as described herein. Therefore, the various embodiments described in detail herein and illustrated in the accompanying figures are for illustrative purposes only and in no way limit the features incorporated in the syringe. While various aspects of the syringe assembly and features have been described in the context of syringes for motorized medical injectors, the syringe assembly and features described herein can also be incorporated into manual syringes for delivering fluids at low injection pressures. For example, in many medical settings where a fluid is to be injected with a manual syringe, the clinician may draw fluid into the syringe from a suitable container, such as a vial, and then prime or purge the syringe to remove any air by holding the syringe upright and pressing the plunger assembly to deliver a small amount of the fluid along with the air contained within the syringe. The expelled fluid may drip down the side of the needle and the syringe body, potentially exposing the clinician to contact with the medical fluid.The syringe assembly and various features described herein can be used in a manual syringe to prevent fluid drips, whether expelled during priming or during injection, from coming into contact with the physician or dripping onto surfaces. Manual syringes comprising various embodiments of the syringe assembly and various features are within the scope of this disclosure. Still other aspects of this disclosure relate to other medical devices comprising the syringe assembly and various features described herein. For example, any medical device that delivers fluids and may leak or drip small amounts of fluid from a fluid opening onto one of its surfaces may benefit from the fluid absorption tabs described herein. Examples of such medical devices include, but are not limited to, catheters (such as the distal end or those portions positioned immediately outside the patient's body), tubing sets, intravenous lines, tubing connectors and clamps, shunts, fluid collectors, valves, suction tubing, surgical instruments, pump fluid outlets, and the like, which may be modified to include the various features described herein. It should be noted that any reference to an aspect means that a particular characteristic, structure, or feature described in relation to that aspect is included in at least one other aspect. Therefore, the appearance of the phrase "in an aspect" in various places throughout the descriptive memory does not necessarily refer to the same aspect. Furthermore, particular characteristics, structures, or features can be combined in any appropriate way within one or more aspects. A person skilled in the art will recognize that the components described herein (e.g., operations), devices, objects, and the accompanying discussion are used as examples for the sake of conceptual clarity, and that various configuration modifications are contemplated. Accordingly, as used here, the specific examples and accompanying discussion are intended to be representative of their more general classes. In general, the use of any specific instance is intended to be representative of its class, and the omission of specific components (e.g., operations), devices, and objects should not be taken as a limitation. With regard to the use of any term in the plural and / or singular in this document, those skilled in the art may translate from plural to singular and / or from singular to plural as appropriate to the context and / or application. The various singular / plural permutations are not expressly stated in this document, for the sake of clarity. The subject matter described herein sometimes illustrates different components contained within it, or connected to other different components. It should be understood that the architectures depicted are merely illustrative, and that, in fact, many other architectures can be implemented to achieve the same functionality. Conceptually, any arrangement of components to achieve the same functionality is effectively "associated" in such a way that the desired functionality is achieved. Therefore, any two components combined here to achieve a particular functionality can be seen as associated with each other, such that the desired functionality is achieved, regardless of the architectures or intermediary components.Similarly, any two components associated in this way can also be viewed as operationally connected or coupled to each other to achieve the desired functionality, and any two components capable of being associated can also be viewed as operationally coupled to each other to achieve the desired functionality. Specific examples of operationally coupled components include, without limitation, physically coupleable and / or physically interacting components, and / or components that interact wirelessly and / or components capable of interacting wirelessly, and / or components that interact logically and / or components capable of interacting logically. Some aspects can be described using the expressions "coupled" and "connected," along with their derivatives. It should be understood that these terms are not intended to be synonymous with each other. For example, some aspects can be described using the term "connected" to indicate that two or more elements are in direct physical or electrical contact with each other. In another example, some aspects can be described using the term "coupled" to indicate that two or more elements are in direct physical or electrical contact. However, the term "coupled" can also mean that two or more elements are not in direct contact with each other, but still cooperate or interact with each other. In some cases, one or more components in this document may be referred to as configured for, operational, adapted, etc. Those skilled in the art will recognize that configured for can generally encompass components in an active state and / or components in an inactive state, and / or components in a wait state, unless the context requires otherwise. Although particular aspects of the subject matter described herein have been shown and described, it will be evident to those skilled in the art that, on the basis of the teachings of this document, changes and modifications may be made without departing from the subject matter described herein and its broader aspects, and therefore the appended claims must encompass within their scope all such changes and modifications that fall within the scope of the subject matter described herein. Those skilled in the art will understand that, in general, the terms used herein, and especially in the appended claims (e.g., the bodies of the appended claims), are generally understood to be open terms (e.g.,(The term "includes" should be interpreted as "including without limitation"; the term "has" should be interpreted as "having at least"; the term "including" should be interpreted as "including without limitation," etc.). Those skilled in the art will further understand that if a specific number of introduced claim mentions is intended, that intention shall be explicitly stated in the claim, and in the absence of such a statement, that intention is not present. For example, as an aid to understanding, the following appended claims may contain the use of the introductory phrases "at least one" and "one or more" to introduce claim mentions.However, the use of such phrases should not be interpreted as meaning that the introduction of a claim statement by the indefinite articles a or an limits any particular claim containing such introduced claim statement to claims containing only one such statement, even when the same claim includes the introductory phrases one or more or at least one and indefinite articles such as a or an (for example, a and / or an should typically be interpreted as at least one or one more); the same applies to the use of definite articles to introduce recitations of claims. Furthermore, even if a specific number of an introduced claim mention is explicitly stated, those skilled in the art will recognize that such mention should typically be interpreted to mean at least the number mentioned (for example, the simple mention of “two mentions,” without any other modifiers, typically means at least two mentions, or two or more mentions). Likewise, in those cases where a convention analogous to “at least one of A, B, and C, etc.” is used, in general, such construction is intended in the sense that a person skilled in the art would understand the convention (for example, a system having at least one of A, B, and C would include, without limitation, systems having A alone, B alone, C alone, A and B together, A and C together, B and C together, and / or A, B, and C together, etc.). In those cases where a convention analogous to “at least one of A, B, or C, etc.” is used,In general, this construction is understood in the sense that a person skilled in the art would understand the convention (for example, a system having at least one of A, B, or C would include, without limitation, systems having A alone, B alone, C alone, A and B together, A and C together, B and C together, and / or A, B, and C together, etc.). Those skilled in the art will further understand that typically a disjunctive word and / or phrase presenting two or more alternative terms, whether in the description, claims, or drawings, should be understood to include the possibilities of including one of the terms, any one of the terms, or both terms, unless the context indicates otherwise. For example, the phrase “A or B” will be understood to include the possibilities “A or “B” or “A and B.” In summary, numerous benefits resulting from the use of the concepts described in this document have been outlined. The foregoing disclosure is for illustrative and descriptive purposes only. It is not intended to be exhaustive nor to limit the precise form disclosed. Modifications or variations are possible in light of the foregoing. The claims presented herein are intended to define the general scope of this disclosure.

Claims

1. A syringe comprising: a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a liquid nozzle at a distal end of the conical distal end wall; a cylindrical load-bearing wall extending axially from the cylindrical side wall beyond a proximal end of the conical distal end wall; and a plurality of radial ribs positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the liquid nozzle over at least a portion of the conical distal end wall.

2. The syringe of claim 1, wherein the plurality of radial ribs define a plurality of liquid retention channels between each pair of adjacent radial ribs, wherein the plurality of liquid retention channels is configured to retain a volume of liquid by capillary adhesion when the syringe is rotated from a first upward-facing position to a second downward-facing position.

3. The syringe of claim 2, wherein the plurality of liquid retention channels are configured to retain a volume of liquid ranging from 0.1 to 0.8 milliliters.

4. The syringe of claim 2, wherein the volume of the liquid containing the plurality of liquid retention channels is determined at least partially from the distance between each adjacent pair of the plurality of radial ribs, the height of each adjacent pair of the plurality of radial ribs, and a distance that each pair of radial ribs extends distally radially inward from the tapered distal end wall.

5. The syringe of any of claims 1 to 4, wherein the plurality of radial ribs increases the load-bearing strength of the tapered distal end wall.

6. The syringe of any of claims 1 to 5, wherein the plurality of radial ribs increases the load-bearing resistance of the cylindrical load-bearing wall.

7. The syringe of any of claims 1 to 6, wherein at least one of the plurality of radial ribs extends a different radial distance inward from the cylindrical load-bearing wall onto the conical distal end wall, compared to the remaining radial ribs of the plurality of radial ribs.

8. The syringe of any of claims 1 to 7, wherein the cylindrical load-bearing wall is configured to abut a retaining surface of a retaining arm of a liquid injector, to retain the syringe within a pressure jacket during a pressurized injection procedure.

9. The syringe of any of claims 1 to 8, wherein the cylindrical load-bearing wall extends axially from the cylindrical side wall of the syringe at an angle of 1 degree to 30 degrees with respect to a longitudinal axis of the syringe.

10. The syringe of any of claims 1 to 9, wherein a distal surface of the cylindrical load-bearing wall is radially inclined from a more proximal inner portion to a more distal outer portion with respect to the longitudinal axis of the syringe.

11. The syringe of claim 10, wherein the angle of the distal surface of the cylindrical load-bearing wall is configured to prevent the entry of liquid between the cylindrical side wall of the syringe and a pressure sleeve in which the syringe is placed.

12. The syringe of claim 10 or claim 11, wherein the angle of the distal surface of the cylindrical load-bearing wall is configured to increase a radially inward force on the retaining arm of the liquid injector.

13. The syringe of any of claims 1 to 12, wherein at least one of the cylindrical load-bearing wall and the plurality of radial ribs enhance a halo refraction effect in a distal portion of the conical distal end wall, of electromagnetic radiation emitted from at least one electromagnetic radiation source in a piston or plunger head of a liquid injector.

14. The syringe of any of claims 1 to 13, further comprising a neck associated with the liquid nozzle at the distal end of the syringe, wherein the neck includes a liquid passage having a plurality of liquid-diverting ribs extending radially inward at least partially into the liquid passage from an internal surface of the neck. ML / a / zuzj / uu 1 15. The syringe of claim 14, wherein the plurality of liquid diversion ribs are configured to divert a liquid flowing through the neck into the syringe, so that the liquid flows along an inner surface of the conical distal end wall and the cylindrical side wall of the syringe.

16. The syringe of claim 14 or claim 15, wherein the plurality of liquid-diverting ribs are configured to minimize the amount of air bubbles in the liquid in the syringe.

17. The syringe of claim 16, wherein the amount of air bubbles in the syringe fluid is minimized by the fluid flowing along the inner surface of the distal end wall and the cylindrical side wall of the syringe.

18. The syringe of any of claims 14 to 17, wherein at least a portion of the plurality of liquid-diverting ribs have different profiles.

19. The syringe of any of claims 14 to 18, wherein at least a portion of the plurality of liquid-diverting ribs extends from the inner surface at different distances into the liquid passage.

20. The syringe of any of claims 1 to 19, wherein the plurality of radial ribs extend along the tapered distal end wall at an angle to the longitudinal axis of the syringe, such that the distance between each adjacent pair of the plurality of radial ribs narrows from the cylindrical load-bearing wall to the liquid nozzle. 21.A syringe comprising: a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a liquid nozzle at a distal end of the conical distal end wall; a plurality of liquid-diverting ribs extending inward from an internal surface of the liquid nozzle; and a plurality of radial ribs positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the liquid nozzle over at least a portion of the conical distal end wall.

22. The syringe of claim 21, further comprising a cylindrical load-bearing wall extending axially from the cylindrical side wall beyond a proximal end of the conical distal end wall.

23. The syringe of claim 21 or claim 22, wherein the plurality of radial ribs defines a plurality of liquid retention channels between each pair of adjacent radial ribs, wherein the plurality of liquid retention channels is configured to retain a volume of liquid by capillary adhesion when the syringe is rotated from a first upward-facing position to a second downward-facing position.

24. The syringe of claim 23, wherein the plurality of liquid retention channels are configured to retain a volume of liquid ranging from 0.1 to 0.8 milliliters.

25. The syringe of claim 23, wherein the volume of the liquid containing the plurality of liquid retention channels is determined at least partially from the distance between each adjacent pair of the plurality of radial ribs, the height of each adjacent pair of the plurality of radial ribs, and a distance that each pair of radial ribs extends distally radially inward from the tapered distal end wall.

26. A syringe comprising: a proximal end, a distal end, and a cylindrical side wall extending between the proximal end and the distal end, wherein the distal end comprises a conical distal end wall and a liquid nozzle at a distal end of the conical distal end wall; and a plurality of liquid-deflecting ribs extending inwardly from an inner surface of the liquid nozzle, wherein the plurality of liquid-deflecting ribs enhance a halo effect of refraction in a distal portion of the conical distal end wall, of electromagnetic radiation emitted from at least one electromagnetic radiation source in a piston or plunger head of a liquid injector.

27. The syringe of claim 26, further comprising a cylindrical load-bearing wall extending axially from the cylindrical side wall beyond a proximal end of the conical distal end wall.

28. The syringe of claim 26 or claim 27, further comprising a plurality of radial ribs positioned around a periphery of the conical distal end wall, wherein a longitudinal axis of the plurality of radial ribs extends radially inward from the cylindrical load-bearing wall toward the liquid nozzle over at least a portion of the conical distal end wall.

29. The syringe of claim 28, wherein the plurality of radial ribs defines a plurality of liquid retention channels between each pair of adjacent radial ribs, wherein the plurality of liquid retention channels is configured to retain a volume of liquid by capillary adhesion when the syringe is rotated from a first upward-facing position to a second downward-facing position.

30. The syringe of claim 29, wherein the plurality of liquid retention channels are configured to retain a volume of liquid ranging from 0.1 to 0.8 milliliters.

31. The syringe of claim 29, wherein the volume of the liquid containing the plurality of liquid retention channels is determined at least partially from the distance between each adjacent pair of the plurality of radial ribs, the height of each adjacent pair of the plurality of radial ribs, and a distance that each pair of radial ribs extends distally radially inward from the tapered distal end wall.

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