PHARMACEUTICAL COMPOSITIONS BASED ON COLLAGEN PEPTIDES AND DEVICES AND METHODS FOR THEIR PRODUCTION AND USE

Abstract

The present invention pertains to the fields of medicinal chemistry, biotechnology, and pharmaceuticals. The invention provides compositions comprising one or more collagen-mimetic peptides, optionally linked to one or more therapeutic compounds or one or more imaging compounds, for use in methods of treating, preventing, improving, curing, and diagnosing certain diseases and physical disorders in humans and veterinary animals, particularly eye diseases and physical disorders of the anterior and posterior segments, para-ocular and extraocular diseases and physical disorders, and nervous or nervous system diseases and physical disorders, as well as methods of manufacturing such compositions. The invention also provides medical devices comprising one or more of such compositions of the invention.The invention also provides methods of using such compositions and devices to treat and diagnose certain diseases and physical disorders in humans and veterinary animals, including anterior and posterior segment eye diseases or disorders, para-ocular and extraocular diseases and physical disorders, and nervous or nervous system diseases or disorders.