Pharmaceutical composition for preventing and treating liver cancer as well as preparation method and application thereof

Abstract

The present invention provides a pharmaceutical composition. for* preventing' and 'treating liver cancer as well as a preparation method and an application thereof. The present invention provides a pharmaceutical composition for preventing and treating liver cancer, including: Radix bupleuri, Radix scutellariae, Endothelium corneum gigeriae galli, Radix astragali, Cortex cinnamomi, Poria and isovalerylshikonin. In the pharmaceutical composition, the traditional Chinese medicine composition improves prevention and treatment effects on liver cancer by regulating qi movement, harmonizing the liver and stomach, invigorating the spleen and promoting diuresis, etc.; and. the isovalerylshikonin. with. toxicity' to liver cancer cells induces apoptosis of liver cancer cells, and inhibits proliferation, migration and invasion. of liver cancer cells. The pharmaceutical composition of the present invention can play a role in preventing and treating liver cancer under synergy by combining the traditional Chinese medicine composition with isovalerylshikonin, and the pharmaceutical composition has selective cytotoxicity to tumor cells.