Cationic lipids for use in lipid nanoparticles

NZ835066APending Publication Date: 2026-07-31ACUITAS THERAPEUTICS INC
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Patent Information

Application Number
NZ835066
Authority / Receiving Office
NZ · NZ
Patent Type
Applications
Current Assignee / Owner
Priority Date
2021-05-14
Filing Date
2021-07-16
Publication Date
2026-07-31

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Abstract

Compounds are provided having the following structure:, (I) or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein a, b, c, d, G1, G2, L1, L2, R1a, R1b, R2a, R2b, R3a, R3b, R4a, R4b, R5, R6, R7, R8 and X are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, nanoparticles comprising the compounds and methods for their use and preparation are also provided.
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