Oral delivery of antisense conjugates targeting PCSK9

NZ835422APending Publication Date: 2026-07-31CIVI BIOPHARMA INC
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Patent Information

Application Number
NZ835422
Authority / Receiving Office
NZ · NZ
Patent Type
Applications
Current Assignee / Owner
Priority Date
2021-09-22
Filing Date
2021-12-10
Publication Date
2026-07-31

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Abstract

The present disclosure provides pharmaceutic compositions for oral delivery comprising an antisense oligonucleotide (e.g., CIVI 008) and an oral delivery agent such as 5-CNAC. In some aspects, the disclosure provides a capsule comprising a dry blend of CIVI 008 and 5-CNAC, and optionally a statin.
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