6-Substituted Pyridazine Compounds as SMARCA2 and / or SMARCA4 Degraders

NZ835689APending Publication Date: 2026-07-31AURIGENE ONCOLOGY LIMITED

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Patent Information

Application Number: NZ835689
Authority / Receiving Office: NZ · NZ
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2020-08-04
Filing Date: 2021-08-03
Publication Date: 2026-07-31

Application Information

Patent Timeline

04 Aug 2020

Priority

03 Aug 2021

Application

NZ835689

31 Jul 2026

Publication

NZ835689A

IPC: C07D487/04

Inventors: ABBINENI, CHANDRASEKHAR; KUILA, BILASH

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Abstract

The present invention provides 6-substituted pyridazine compounds of formula (I), which are therapeutically useful as SMARCA2 and / or SMARCA4 degraders. These compounds are useful in the treatment and / or delaying progression of diseases or disorders dependent upon SMARCA2 and / or SMARCA4 in a subject. The present invention also provides preparation of the compounds and pharmaceutical compositions comprising at least one of the compounds of formula (I) or a pharmaceutically acceptable salt, or a stereoisomer or a tautomer or a prodrug thereof.

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