Methods of treating cardiac disorders and congestive heart failure and administering AAV vectors

NZ835854APending Publication Date: 2026-08-28ASKBIO INC

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Patent Information

Application Number: NZ835854
Authority / Receiving Office: NZ · NZ
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2021-06-23
Filing Date: 2021-08-05
Publication Date: 2026-08-28

Application Information

Patent Timeline

23 Jun 2021

Priority

05 Aug 2021

Application

NZ835854

28 Aug 2026

Publication

NZ835854A

IPC: A61P9/04; A61P9/00; A61K38/16; C12N15/861; A61K48/00

Inventors: COOPER, SINCLAIR; EVRIPIOTI, ANTONIA

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Abstract

The present invention relates to methods of administration of rAAV vectors in a single administration method comprising a series of sub-administrations of sub-doses of rAAV vectors. The present invention also relates to rAAV vectors comprising cardiac-specific promoters, cardiac-cell specific promoters, multi-cell cardiac specific promoters, and elements thereof. The invention also relates to rAAV vectors, pharmaceutical compositions and uses thereof in methods for treating cardiovascular disease, heart diseases and heart failure in subjects in need thereof.

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