ANTI-INTEGRIN ALPHA V BETA 8 ANTIBODIES AND PROCEDURES FOR USE

Abstract

The present invention relates to an antibody, or antigen-binding portion thereof, that binds specifically to alpha-beta8. The invention also relates to an isolated nucleic acid encoding the antibody, a vector comprising the nucleic acid, and a host cell comprising either the nucleic acid or the vector. The invention further relates to a process for producing the antibody and to a pharmaceutical composition comprising the antibody or antigen-binding portion thereof. The antibody, or antigen-binding portion thereof, or the pharmaceutical composition enables the treatment of cancer, where the cancer is selected from a list including ovarian cancer, triple-negative breast cancer, and non-small cell lung carcinoma, among other cancer types.