Solid forms of 3-((1r,3r)-1-(2,6-difluoro-4-((1-(3fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9tetrahydro-2h-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol and processes for preparing fused tricyclic compounds comprising a substituted phe

PH12020500676B1Active Publication Date: 2026-08-12F HOFFMANN LA ROCHE & CO AG
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Patent Information

Application Number
PH12020500676
Authority / Receiving Office
PH · PH
Patent Type
Patents
Current Assignee / Owner
Filing Date
2020-12-17
Publication Date
2026-08-12
Estimated Expiration
2040-12-17
Patent Text Reader

Abstract

Provided herein are solid forms, salts such as compound B, and formulations of 3((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol, processes and synthesis thereof, and methods of their use in the treatment of cancer.
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