Therapeutically administrable high dose non-aqueous curcuminoid solutions

Abstract

A method involves dissolving a curcuminoid in glycerol to make an administrable solution. An alkali salt is added to the glycerol to increase the solubility of the curcuminoid in the glycerol to more than 20 milligrams curcuminoid per millilitre of glycerol (and up to in excess of 200 milligrams curcuminoid per millilitre of glycerol with the addition of sufficient alkali salt in embodiments). The resulting administrable solution can be administered (such as by way of intramuscular injection) as is without the need of an aqueous emulsion and can be stored for more than 24 hours without curcuminoid precipitation.