Stable antibody formulation
PH12022551721B1Active Publication Date: 2026-10-02REGENERON PHARMACEUTICALS INC
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Patent Information
- Application Number
- PH12022551721
- Authority / Receiving Office
- PH · PH
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2022-07-11
- Publication Date
- 2026-10-02
- Estimated Expiration
- 2042-07-11
Abstract
The present disclosure provides stable pharmaceutical formulations comprising a human antibody that specifically binds to Ebola Virus (EBOV). In certain embodiments, the formulations contain, in addition to an anti-EBOV antibody, a buffer, an amino acid, a non ionic surfactant, and a stabilizer. The pharmaceutical formulations of the present disclosure exhibit a substantial degree of antibody stability upon stress, for example, agitation during transport, and storage, for example, storage at temperatures greater than 40°C.
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