Inhibitors of APOL1 and methods of using same

PH12023550304B1Active Publication Date: 2026-08-05VERTEX PHARMACEUTICALS INC
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Patent Information

Application Number
PH12023550304
Authority / Receiving Office
PH · PH
Patent Type
Patents
Current Assignee / Owner
Filing Date
2023-02-02
Publication Date
2026-08-05
Estimated Expiration
2043-02-02
Patent Text Reader

Abstract

The disclosure provides at least one entity chosen from compounds of Formula I, a tautomer thereof, a deuterated derivative of that compound or tautomer, and a pharmaceutically acceptable salt of any of the foregoing, compositions comprising the same, and methods of using the same, including uses in treating APOL1-mediated diseases, including pancreatic cancer, focal segmental glomerulosclerosis (FSGS), and / or non-diabetic kidney disease (NDKD).
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