A substituted tetrahydroisoquinolylsulphonamide compound

Abstract

Compound corresponding to the formula I: in which: n may adopt a value from 1 to 6; -(C)n- represents a –C1-6 alkylidene group, optionally substituted by 1 to 4 substituents; Rl represents a hydrogen atom, a C1-6 alkyl group; R2 represents a hydrogen atom, a C1-6 alkyl or C3-6 cycloalkyl group, each of which is optionally substituted by 1 to 4 substituents; B represents NR3R4, where R3 and R4 represent, independently of one another, a C1-b alkyl group or a hydrogen atom; or R3 and R4 together represent a C1-6 alkylidene group, a C2-8 alkenylidene group, a C1-3 alkylidene-O-C1-3 alkylidene group, or a group C1-3 alkylidene-N(R5)-C1-3 alkylidene in which R5 represents a hydrogen atom or a C1-3 alkyl or C1-6 alkylcarbonyl group, it being possible for these C1-3 alkyl and C1-6 alkyl¬carbonyl groups to be substituted; or a cyclic amino, bonded via a carbon to the group -NRl-(C)n-, such as aziridine, azetidine, pyrrolidine, piperidine or morpholine; the groups R3 and R4 and the cyclic amino being optionally substituted and the nitrogen atom being optionally substituted.