2-{3-tert-Butylsulfanyl -5(pyridin-2 ylmethylsulfanyl)-1-[4-(5 trifluoromethyl-pyridin-2-yl)-benzyl]-1H indol-2-ylmethyl}-2-ethyl-butyric acid

Abstract

Described herein are compounds and pharmaceutical composition containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene dependent or leukotriene mediated conditions or diseases.