Substituted 1,2,4,5-tetrahydro-3h benzazepine compound
PK140795AUndetermined Publication Date: 2010-06-09LES LAB SERVIER SA
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Patent Information
- Application Number
- PK200801073
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Publication Date
- 2010-06-09
Abstract
Compound of formula (I):wherein: - R1 represents a hydrogen atom or a group selected from cycloalkyl, benzyl and optionally substituted alkyl, - R3, R4 and R5 each represent a hydrogen atom or a hydroxy, methyl, OSO2R10, -OCOR10 or optionally substituted alkoxy group, or R2 and R3, or R3 and R4, or R4 and R5 together form a group -O-(CH2)q-O-, -O-CH=CH-O- or O-CH=CH-, - R6, R7, R8 and R9 each represent a hydrogen atom or an alkoxy group, or R6 and R7, or R7 and R8, or R8 and R9 together form a group -O-(CH2)q-O-, - R10 represents a group selected from linear or branched C1-C6alkoxy, NR11R11 and optionally substituted alkyl, - R11 and R'11 each represent a hydrogen atom or an alkyl group, or R11 and R11 together with the nitrogen atom carrying them form an optionally substituted, monocyclic or bicyclic, nitrogen-containing heterocycle, X represents 0, NH or CH2, - m and p each represent 0 or 1, n and q each represent 1 or 2, and a pharmaceutically composition comprising thereof.
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